40 items (Mandrillus leucophaeus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSMLEP00000002280	Biotin carboxylation domain-containing protein. (205 aa)
	NR4A3	Nuclear receptor subfamily 4 group A member 3. (637 aa)
	TSKU	Tsukushi, small leucine rich proteoglycan. (353 aa)
	CRTC1	CREB regulated transcription coactivator 1. (570 aa)
	EDN2	Endothelin 2. (178 aa)
	ALK	Tyrosine-protein kinase receptor. (1620 aa)
	PASK	PAS domain containing serine/threonine kinase. (1321 aa)
	PRKAA1	Non-specific serine/threonine protein kinase. (559 aa)
	SLC35D3	Solute carrier family 35 member D3. (416 aa)
	PM20D1	Peptidase M20 domain containing 1. (502 aa)
	MFSD2A	Major facilitator superfamily domain containing 2A. (543 aa)
	MEX3C	Mex-3 RNA binding family member C. (526 aa)
	OMA1	OMA1 zinc metallopeptidase. (524 aa)
	FMO4	Dimethylaniline monooxygenase [N-oxide-forming]. (558 aa)
	MLXIPL	MLX interacting protein like. (784 aa)
	AMPD2	AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (879 aa)
	TRPV4	Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (871 aa)
	EIF4G1	Eukaryotic translation initiation factor 4 gamma 1. (1598 aa)
	RRP8	Ribosomal RNA-processing protein 8; Essential component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone- modifying enzymes. The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys-9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus. In the complex, RRP8 binds to H3K9me2 and pr [...] (456 aa)
	PPARGC1A	PPARG coactivator 1 alpha. (798 aa)
	PIK3CA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	MRAP2	Melanocortin 2 receptor accessory protein 2. (205 aa)
	DLL1	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (606 aa)
	CRTC3	CREB regulated transcription coactivator 3. (596 aa)
	LEPR	Leptin receptor. (1163 aa)
	PRKAA2	Non-specific serine/threonine protein kinase. (542 aa)
	METRNL	Meteorin like, glial cell differentiation regulator. (254 aa)
	SIRT1	Sirtuin 1. (661 aa)
	IRX3	Homeobox domain-containing protein. (284 aa)
	NMU	Neuromedin U. (165 aa)
	FLCN	Folliculin. (515 aa)
	ENSMLEP00000015404	Fork-head domain-containing protein. (531 aa)
	NR1D2	Nuclear receptor subfamily 1 group D member 2. (569 aa)
	FMO2	Dimethylaniline monooxygenase [N-oxide-forming]. (535 aa)
	ENSMLEP00000014201	Uncharacterized protein. (478 aa)
	CD36	CD36 molecule; Belongs to the CD36 family. (472 aa)
	STAT3	Signal transducer and activator of transcription. (693 aa)
	ENSMLEP00000008990	Uncharacterized protein. (858 aa)
	FMO1	Dimethylaniline monooxygenase [N-oxide-forming]. (532 aa)
	SGIP1	SH3 domain GRB2 like endophilin interacting protein 1. (859 aa)

Your Current Organism:

Mandrillus leucophaeus

NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALK	PIK3CA	ENSMLEP00000036999	ENSMLEP00000019594	Tyrosine-protein kinase receptor.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.931
ALK	STAT3	ENSMLEP00000036999	ENSMLEP00000012622	Tyrosine-protein kinase receptor.	Signal transducer and activator of transcription.	0.673
CRTC1	CRTC3	ENSMLEP00000040581	ENSMLEP00000004839	CREB regulated transcription coactivator 1.	CREB regulated transcription coactivator 3.	0.865
CRTC3	CRTC1	ENSMLEP00000004839	ENSMLEP00000040581	CREB regulated transcription coactivator 3.	CREB regulated transcription coactivator 1.	0.865
CRTC3	ENSMLEP00000014201	ENSMLEP00000004839	ENSMLEP00000014201	CREB regulated transcription coactivator 3.	Uncharacterized protein.	0.865
CRTC3	PPARGC1A	ENSMLEP00000004839	ENSMLEP00000020141	CREB regulated transcription coactivator 3.	PPARG coactivator 1 alpha.	0.431
CRTC3	PRKAA1	ENSMLEP00000004839	ENSMLEP00000034493	CREB regulated transcription coactivator 3.	Non-specific serine/threonine protein kinase.	0.414
CRTC3	PRKAA2	ENSMLEP00000004839	ENSMLEP00000003668	CREB regulated transcription coactivator 3.	Non-specific serine/threonine protein kinase.	0.414
ENSMLEP00000002280	ENSMLEP00000008990	ENSMLEP00000002280	ENSMLEP00000008990	Biotin carboxylation domain-containing protein.	Uncharacterized protein.	0.900
ENSMLEP00000002280	PRKAA1	ENSMLEP00000002280	ENSMLEP00000034493	Biotin carboxylation domain-containing protein.	Non-specific serine/threonine protein kinase.	0.654
ENSMLEP00000002280	PRKAA2	ENSMLEP00000002280	ENSMLEP00000003668	Biotin carboxylation domain-containing protein.	Non-specific serine/threonine protein kinase.	0.654
ENSMLEP00000008990	ENSMLEP00000002280	ENSMLEP00000008990	ENSMLEP00000002280	Uncharacterized protein.	Biotin carboxylation domain-containing protein.	0.900
ENSMLEP00000008990	PRKAA1	ENSMLEP00000008990	ENSMLEP00000034493	Uncharacterized protein.	Non-specific serine/threonine protein kinase.	0.912
ENSMLEP00000008990	PRKAA2	ENSMLEP00000008990	ENSMLEP00000003668	Uncharacterized protein.	Non-specific serine/threonine protein kinase.	0.918
ENSMLEP00000014201	CRTC3	ENSMLEP00000014201	ENSMLEP00000004839	Uncharacterized protein.	CREB regulated transcription coactivator 3.	0.865
ENSMLEP00000015404	PIK3CA	ENSMLEP00000015404	ENSMLEP00000019594	Fork-head domain-containing protein.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.411
ENSMLEP00000015404	PPARGC1A	ENSMLEP00000015404	ENSMLEP00000020141	Fork-head domain-containing protein.	PPARG coactivator 1 alpha.	0.946
ENSMLEP00000015404	PRKAA1	ENSMLEP00000015404	ENSMLEP00000034493	Fork-head domain-containing protein.	Non-specific serine/threonine protein kinase.	0.918
ENSMLEP00000015404	PRKAA2	ENSMLEP00000015404	ENSMLEP00000003668	Fork-head domain-containing protein.	Non-specific serine/threonine protein kinase.	0.918
ENSMLEP00000015404	SIRT1	ENSMLEP00000015404	ENSMLEP00000005263	Fork-head domain-containing protein.	Sirtuin 1.	0.983