node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AP2A2 | AP2M1 | ENSMLEP00000011708 | ENSMLEP00000026079 | AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] | AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...] | 0.996 |
AP2A2 | CLTC | ENSMLEP00000011708 | ENSMLEP00000013187 | AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] | Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. | 0.948 |
AP2M1 | AP2A2 | ENSMLEP00000026079 | ENSMLEP00000011708 | AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...] | AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] | 0.996 |
AP2M1 | CLTC | ENSMLEP00000026079 | ENSMLEP00000013187 | AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...] | Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. | 0.959 |
CLTC | AP2A2 | ENSMLEP00000013187 | ENSMLEP00000011708 | Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. | AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] | 0.948 |
CLTC | AP2M1 | ENSMLEP00000013187 | ENSMLEP00000026079 | Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. | AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...] | 0.959 |
CLTC | HSPA2 | ENSMLEP00000013187 | ENSMLEP00000029810 | Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. | Heat shock protein family A (Hsp70) member 2; Belongs to the heat shock protein 70 family. | 0.437 |
CTNNB1 | FYN | ENSMLEP00000009207 | ENSMLEP00000015574 | Catenin beta 1. | Tyrosine-protein kinase. | 0.995 |
CTNNB1 | GAPDH | ENSMLEP00000009207 | ENSMLEP00000003862 | Catenin beta 1. | Glyceraldehyde-3-phosphate dehydrogenase. | 0.620 |
CTNNB1 | RRM1 | ENSMLEP00000009207 | ENSMLEP00000037579 | Catenin beta 1. | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.562 |
CTNNB1 | SMAD2 | ENSMLEP00000009207 | ENSMLEP00000027206 | Catenin beta 1. | Mothers against decapentaplegic homolog. | 0.752 |
CTNNB1 | TP53 | ENSMLEP00000009207 | ENSMLEP00000037099 | Catenin beta 1. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.486 |
FYN | CTNNB1 | ENSMLEP00000015574 | ENSMLEP00000009207 | Tyrosine-protein kinase. | Catenin beta 1. | 0.995 |
GAPDH | CTNNB1 | ENSMLEP00000003862 | ENSMLEP00000009207 | Glyceraldehyde-3-phosphate dehydrogenase. | Catenin beta 1. | 0.620 |
GAPDH | HSPA2 | ENSMLEP00000003862 | ENSMLEP00000029810 | Glyceraldehyde-3-phosphate dehydrogenase. | Heat shock protein family A (Hsp70) member 2; Belongs to the heat shock protein 70 family. | 0.621 |
GAPDH | TP53 | ENSMLEP00000003862 | ENSMLEP00000037099 | Glyceraldehyde-3-phosphate dehydrogenase. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.580 |
HSPA2 | CLTC | ENSMLEP00000029810 | ENSMLEP00000013187 | Heat shock protein family A (Hsp70) member 2; Belongs to the heat shock protein 70 family. | Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. | 0.437 |
HSPA2 | GAPDH | ENSMLEP00000029810 | ENSMLEP00000003862 | Heat shock protein family A (Hsp70) member 2; Belongs to the heat shock protein 70 family. | Glyceraldehyde-3-phosphate dehydrogenase. | 0.621 |
HSPA2 | TP53 | ENSMLEP00000029810 | ENSMLEP00000037099 | Heat shock protein family A (Hsp70) member 2; Belongs to the heat shock protein 70 family. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.417 |
KEAP1 | TP53 | ENSMLEP00000025129 | ENSMLEP00000037099 | Kelch like ECH associated protein 1. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.407 |