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SNX12 SNX12 SNAP47 SNAP47 GOLPH3 GOLPH3 VPS35 VPS35 HGS HGS VPS35L VPS35L LLGL1 LLGL1 ACAP2 ACAP2 VPS26A VPS26A PTPN23 PTPN23 ARFGEF2 ARFGEF2 GRIP2 GRIP2 TTC17 TTC17 GOLGA4 GOLGA4 CCDC93 CCDC93 C16orf70 C16orf70 GOLGA7 GOLGA7 RAB11B RAB11B EXOC4 EXOC4 ANKRD50 ANKRD50 EXOC6 EXOC6 CHIC1 CHIC1 SNX4 SNX4 DNM2 DNM2 RAB14 RAB14 EHD1 EHD1 SNX17 SNX17 VPS52 VPS52 SNX30 SNX30 CLSTN1 CLSTN1 LMTK2 LMTK2 EXOC2 EXOC2 SEC16A SEC16A EPG5 EPG5 CCDC22 CCDC22 RAB11FIP4 RAB11FIP4 RAB8B RAB8B RABEP1 RABEP1 ARFRP1 ARFRP1 RAB34 RAB34 GGA2 GGA2 ENSMLEP00000020342 ENSMLEP00000020342 VPS51 VPS51 MICALL1 MICALL1 LOC105544932 LOC105544932 MICALL2 MICALL2 EIPR1 EIPR1 ENSMLEP00000022792 ENSMLEP00000022792 STX1B STX1B ENTR1 ENTR1 ANKRD27 ANKRD27 OSBPL5 OSBPL5 VPS50 VPS50 ENSMLEP00000024580 ENSMLEP00000024580 SNX27 SNX27 EHD4 EHD4 STX6 STX6 ARL3 ARL3 VPS39 VPS39 SNF8 SNF8 GGA1 GGA1 ENSMLEP00000026929 ENSMLEP00000026929 VPS26C VPS26C WASHC1 WASHC1 BBS1 BBS1 BBS2 BBS2 ENSMLEP00000028984 ENSMLEP00000028984 RAB10 RAB10 ENSMLEP00000030691 ENSMLEP00000030691 KIF13A KIF13A EXOC6B EXOC6B LRRC1 LRRC1 DENND1C DENND1C RAB31 RAB31 RAB35 RAB35 STX3 STX3 NSG1 NSG1 SNAP25 SNAP25 RAB7A RAB7A EXOC5 EXOC5 GGA3 GGA3 RAB17 RAB17 RAB11FIP3 RAB11FIP3 SLC1A1 SLC1A1 RAB13 RAB13 KIAA1109 KIAA1109 ENSMLEP00000036399 ENSMLEP00000036399 BLZF1 BLZF1 ARHGAP44 ARHGAP44 COMMD1 COMMD1 GOLPH3L GOLPH3L CMTM6 CMTM6 ANK3 ANK3 DENND1B DENND1B RAB3IP RAB3IP GRIPAP1 GRIPAP1 SCRIB SCRIB TRARG1 TRARG1 DENND1A DENND1A CHIC2 CHIC2 AMN AMN PREPL PREPL STEAP2 STEAP2 ENSMLEP00000040190 ENSMLEP00000040190 EHD2 EHD2 MACF1 MACF1 LOC105538037 LOC105538037 ENSMLEP00000000526 ENSMLEP00000000526 EXOC1 EXOC1 VPS53 VPS53 EXOC1L EXOC1L LOC105550866 LOC105550866 ARF6 ARF6 GRIP1 GRIP1 VPS29 VPS29 ENSMLEP00000004908 ENSMLEP00000004908 EHD3 EHD3 EPS15 EPS15 EXOC8 EXOC8 RAB26 RAB26 ATP6AP1 ATP6AP1 SPTBN1 SPTBN1 ARL4C ARL4C
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SNX12Sorting nexin 12. (174 aa)
SNAP47Synaptosome associated protein 47. (419 aa)
GOLPH3Golgi phosphoprotein 3. (232 aa)
VPS35Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. (664 aa)
HGSHepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] (815 aa)
VPS35LVPS35 endosomal protein sorting factor like. (1006 aa)
LLGL1LLGL scribble cell polarity complex component 1. (1075 aa)
ACAP2ArfGAP with coiled-coil, ankyrin repeat and PH domains 2. (768 aa)
VPS26AVPS26, retromer complex component A. (334 aa)
PTPN23Protein tyrosine phosphatase non-receptor type 23. (1634 aa)
ARFGEF2ADP ribosylation factor guanine nucleotide exchange factor 2. (1713 aa)
GRIP2Glutamate receptor interacting protein 2. (1143 aa)
TTC17Tetratricopeptide repeat domain 17. (1198 aa)
GOLGA4Golgin A4. (2242 aa)
CCDC93Coiled-coil domain containing 93. (631 aa)
C16orf70Chromosome 16 open reading frame 70. (363 aa)
GOLGA7Golgin A7. (146 aa)
RAB11BUncharacterized protein. (448 aa)
EXOC4Uncharacterized protein. (444 aa)
ANKRD50Ankyrin repeat domain 50. (1429 aa)
EXOC6Exocyst complex component; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. (804 aa)
CHIC1Cysteine rich hydrophobic domain 1. (224 aa)
SNX4Sorting nexin 4. (369 aa)
DNM2Dynamin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (810 aa)
RAB14RAB14, member RAS oncogene family. (215 aa)
EHD1EH domain containing 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (548 aa)
SNX17Sorting nexin 17. (475 aa)
VPS52VPS52 subunit of GARP complex. (723 aa)
SNX30Sorting nexin family member 30. (505 aa)
CLSTN1Calsyntenin 1. (975 aa)
LMTK2Lemur tyrosine kinase 2. (1467 aa)
EXOC2Exocyst complex component 2; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family. (924 aa)
SEC16AProtein transport protein sec16; Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus. (2330 aa)
EPG5Ectopic P-granules autophagy protein 5 homolog. (2557 aa)
CCDC22Coiled-coil domain containing 22. (627 aa)
RAB11FIP4RAB11 family interacting protein 4. (584 aa)
RAB8BRAB8B, member RAS oncogene family. (207 aa)
RABEP1Rabaptin, RAB GTPase binding effector protein 1. (859 aa)
ARFRP1ADP ribosylation factor related protein 1. (201 aa)
RAB34RAB34, member RAS oncogene family. (225 aa)
GGA2Golgi associated, gamma adaptin ear containing, ARF binding protein 2. (589 aa)
ENSMLEP00000020342Uncharacterized protein. (69 aa)
VPS51VPS51 subunit of GARP complex. (727 aa)
MICALL1MICAL like 1. (795 aa)
LOC105544932Uncharacterized protein. (164 aa)
MICALL2MICAL like 2. (834 aa)
EIPR1EARP complex and GARP complex interacting protein 1. (384 aa)
ENSMLEP00000022792V-SNARE coiled-coil homology domain-containing protein. (109 aa)
STX1BSyntaxin 1B; Belongs to the syntaxin family. (245 aa)
ENTR1Endosome associated trafficking regulator 1. (388 aa)
ANKRD27Ankyrin repeat domain 27. (1033 aa)
OSBPL5Oxysterol-binding protein; Belongs to the OSBP family. (879 aa)
VPS50VPS50 subunit of EARP/GARPII complex. (964 aa)
ENSMLEP00000024580Uncharacterized protein. (51 aa)
SNX27Sorting nexin 27. (435 aa)
EHD4EH domain containing 4; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (462 aa)
STX6Syntaxin 6; Belongs to the syntaxin family. (255 aa)
ARL3ADP ribosylation factor like GTPase 3; Belongs to the small GTPase superfamily. Arf family. (103 aa)
VPS39VPS39 subunit of HOPS complex. (895 aa)
SNF8Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family. (258 aa)
GGA1Golgi associated, gamma adaptin ear containing, ARF binding protein 1. (639 aa)
ENSMLEP00000026929IF rod domain-containing protein; Belongs to the intermediate filament family. (200 aa)
VPS26CVPS26 endosomal protein sorting factor C. (297 aa)
WASHC1WASH complex subunit 1. (467 aa)
BBS1BBS1 domain-containing protein. (593 aa)
BBS2Bardet-Biedl syndrome 2 protein homolog. (721 aa)
ENSMLEP00000028984Uncharacterized protein. (196 aa)
RAB10RAB10, member RAS oncogene family. (200 aa)
ENSMLEP00000030691Uncharacterized protein. (160 aa)
KIF13AKinesin family member 13A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1713 aa)
EXOC6BExocyst complex component; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. (815 aa)
LRRC1Leucine rich repeat containing 1. (507 aa)
DENND1CDENN domain containing 1C. (801 aa)
RAB31RAB31, member RAS oncogene family. (259 aa)
RAB35RAB35, member RAS oncogene family. (319 aa)
STX3Syntaxin 3; Belongs to the syntaxin family. (290 aa)
NSG1Neuronal vesicle trafficking associated 1. (185 aa)
SNAP25Synaptosomal-associated protein; Belongs to the SNAP-25 family. (206 aa)
RAB7ARAB7A, member RAS oncogene family. (207 aa)
EXOC5Exocyst complex component 5. (711 aa)
GGA3Golgi associated, gamma adaptin ear containing, ARF binding protein 3. (723 aa)
RAB17RAB17, member RAS oncogene family. (212 aa)
RAB11FIP3RAB11 family interacting protein 3. (443 aa)
SLC1A1Solute carrier family 1 member 1. (524 aa)
RAB13Uncharacterized protein. (203 aa)
KIAA1109KIAA1109. (5005 aa)
ENSMLEP00000036399Uncharacterized protein. (95 aa)
BLZF1Basic leucine zipper nuclear factor 1. (404 aa)
ARHGAP44Rho GTPase activating protein 44. (818 aa)
COMMD1Copper metabolism domain containing 1. (190 aa)
GOLPH3LGolgi phosphoprotein 3 like. (285 aa)
CMTM6MARVEL domain-containing protein. (183 aa)
ANK3Ankyrin 3. (4377 aa)
DENND1BDENN domain containing 1B. (733 aa)
RAB3IPRAB3A interacting protein. (481 aa)
GRIPAP1GRIP1 associated protein 1. (841 aa)
SCRIBScribble planar cell polarity protein. (1445 aa)
TRARG1Trafficking regulator of GLUT4 (SLC2A4) 1. (177 aa)
DENND1ADENN domain containing 1A. (1007 aa)
CHIC2Cysteine rich hydrophobic domain 2. (165 aa)
AMNAmnion associated transmembrane protein. (296 aa)
PREPLProlyl endopeptidase like. (727 aa)
STEAP2STEAP2 metalloreductase. (490 aa)
ENSMLEP00000040190IF rod domain-containing protein; Belongs to the intermediate filament family. (407 aa)
EHD2EH domain containing 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (529 aa)
MACF1Microtubule actin crosslinking factor 1. (7541 aa)
LOC105538037IF rod domain-containing protein; Belongs to the intermediate filament family. (398 aa)
ENSMLEP00000000526Uncharacterized protein. (64 aa)
EXOC1Exocyst complex component 1. (901 aa)
VPS53VPS53 subunit of GARP complex. (830 aa)
EXOC1LExocyst complex component 1 like. (172 aa)
LOC105550866IF rod domain-containing protein; Belongs to the intermediate filament family. (420 aa)
ARF6ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (175 aa)
GRIP1Glutamate receptor interacting protein 1. (1128 aa)
VPS29Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. (214 aa)
ENSMLEP00000004908Uncharacterized protein. (525 aa)
EHD3EH domain containing 3; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (535 aa)
EPS15Epidermal growth factor receptor pathway substrate 15. (859 aa)
EXOC8Exocyst complex component 8. (727 aa)
RAB26RAB26, member RAS oncogene family. (190 aa)
ATP6AP1ATPase H+ transporting accessory protein 1. (470 aa)
SPTBN1Spectrin beta chain; Belongs to the spectrin family. (2366 aa)
ARL4CADP ribosylation factor like GTPase 4C; Belongs to the small GTPase superfamily. Arf family. (202 aa)
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
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