STRINGSTRING
NRXN1 NRXN1 DOC2B DOC2B DDC DDC NLGN1 NLGN1 STON1 STON1 SYT8 SYT8 SYNPR SYNPR SNCG SNCG DOC2A DOC2A DNM3 DNM3 STX11 STX11 ENSMLEP00000003309 ENSMLEP00000003309 PACSIN1 PACSIN1 ARF6 ARF6 SYT5 SYT5 SH3GL1 SH3GL1 SYNJ2 SYNJ2 SH3GL3 SH3GL3 SV2A SV2A OTOF OTOF SNAP47 SNAP47 SYT12 SYT12 SYT2 SYT2 RAP1A RAP1A CTNNB1 CTNNB1 ENSMLEP00000009668 ENSMLEP00000009668 AP3D1 AP3D1 SYT9 SYT9 CADPS CADPS BIN1 BIN1 SNCB SNCB SYT1 SYT1 OPHN1 OPHN1 SYN3 SYN3 DNAJC6 DNAJC6 SNAPIN SNAPIN ENSMLEP00000012301 ENSMLEP00000012301 ERC2 ERC2 SYNDIG1 SYNDIG1 SYN2 SYN2 ENSMLEP00000013488 ENSMLEP00000013488 CPLX4 CPLX4 NOSTRIN NOSTRIN ENSMLEP00000014628 ENSMLEP00000014628 PIP5K1C PIP5K1C DNM2 DNM2 RAB27B RAB27B AP3S1 AP3S1 AP3B1 AP3B1 DNM1 DNM1 SYT7 SYT7 UNC13C UNC13C NLGN3 NLGN3 AP3B2 AP3B2 SLC18A2 SLC18A2 ITSN2 ITSN2 SLC17A7 SLC17A7 ITSN1 ITSN1 PSEN1 PSEN1 CDK5 CDK5 WNT3A WNT3A SH3GL2 SH3GL2 TH TH UNC13A UNC13A GIT1 GIT1 ENSMLEP00000020744 ENSMLEP00000020744 CPLX3 CPLX3 UNC13B UNC13B STX1B STX1B AP3M2 AP3M2 SLC17A6 SLC17A6 PPFIA3 PPFIA3 NLGN2 NLGN2 BTBD8 BTBD8 ENSMLEP00000025021 ENSMLEP00000025021 ENSMLEP00000025432 ENSMLEP00000025432 AMPH AMPH SYNJ1 SYNJ1 CPLX2 CPLX2 PLD2 PLD2 PRRT2 PRRT2 ENSMLEP00000026939 ENSMLEP00000026939 PICALM PICALM BRSK1 BRSK1 SLC18A1 SLC18A1 ACTB ACTB SNAP91 SNAP91 STX2 STX2 STX4 STX4 SLC17A8 SLC17A8 LRRC1 LRRC1 SNAP23 SNAP23 STX3 STX3 RIMS1 RIMS1 SNAP25 SNAP25 STON2 STON2 CANX CANX GIT2 GIT2 BLOC1S6 BLOC1S6 STX1A STX1A SYP SYP BRAF BRAF DNAJC5 DNAJC5 SYN1 SYN1 VAMP1 VAMP1 KIAA1109 KIAA1109 AP2B1 AP2B1 FCHO2 FCHO2 RIMS3 RIMS3 SCRIB SCRIB P2RX7 P2RX7 DENND1A DENND1A CADPS2 CADPS2 GAK GAK NAPA NAPA CTBP2 CTBP2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NRXN1Neurexin 1. (1182 aa)
DOC2BDouble C2 domain beta. (357 aa)
DDCDopa decarboxylase. (480 aa)
NLGN1Neuroligin 1. (823 aa)
STON1Stonin-1; May be involved in the endocytic machinery. (735 aa)
SYT8Synaptotagmin 8. (387 aa)
SYNPRSynaptoporin. (245 aa)
SNCGUncharacterized protein; Belongs to the synuclein family. (124 aa)
DOC2ADouble C2-like domain-containing protein. (400 aa)
DNM3Dynamin 3; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (864 aa)
STX11Syntaxin 11; Belongs to the syntaxin family. (287 aa)
ENSMLEP00000003309PDZ domain-containing protein. (442 aa)
PACSIN1Protein kinase C and casein kinase substrate in neurons 1. (444 aa)
ARF6ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (175 aa)
SYT5Synaptotagmin 5. (386 aa)
SH3GL1SH3 domain containing GRB2 like 1, endophilin A2. (367 aa)
SYNJ2Synaptojanin 2. (1456 aa)
SH3GL3SH3 domain containing GRB2 like 3, endophilin A3. (306 aa)
SV2ASynaptic vesicle glycoprotein 2A. (742 aa)
OTOFOtoferlin. (1848 aa)
SNAP47Synaptosome associated protein 47. (419 aa)
SYT12Synaptotagmin 12. (421 aa)
SYT2Synaptotagmin 2. (419 aa)
RAP1ARAP1A, member of RAS oncogene family. (184 aa)
CTNNB1Catenin beta 1. (781 aa)
ENSMLEP00000009668Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (383 aa)
AP3D1AP-3 complex subunit delta; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane. (1181 aa)
SYT9Synaptotagmin 9. (491 aa)
CADPSCalcium dependent secretion activator. (1242 aa)
BIN1Bridging integrator 1. (593 aa)
SNCBBeta-synuclein; Belongs to the synuclein family. (134 aa)
SYT1Synaptotagmin 1. (422 aa)
OPHN1Oligophrenin 1. (775 aa)
SYN3Synapsin III. (580 aa)
DNAJC6DnaJ heat shock protein family (Hsp40) member C6. (942 aa)
SNAPINSNARE-associated protein Snapin; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling; Belongs to t [...] (136 aa)
ENSMLEP00000012301Protein kinase domain-containing protein. (294 aa)
ERC2ELKS/RAB6-interacting/CAST family member 2. (957 aa)
SYNDIG1Synapse differentiation inducing 1. (258 aa)
SYN2Synapsin II. (479 aa)
ENSMLEP00000013488C2 domain-containing protein. (356 aa)
CPLX4Complexin 4. (160 aa)
NOSTRINNitric oxide synthase trafficking. (536 aa)
ENSMLEP00000014628Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (430 aa)
PIP5K1CPhosphatidylinositol-4-phosphate 5-kinase type 1 gamma. (669 aa)
DNM2Dynamin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (810 aa)
RAB27BRAB27B, member RAS oncogene family. (218 aa)
AP3S1AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (170 aa)
AP3B1AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1087 aa)
DNM1Dynamin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (797 aa)
SYT7Synaptotagmin 7. (684 aa)
UNC13CUnc-13 homolog C. (2186 aa)
NLGN3Neuroligin 3. (848 aa)
AP3B2AP-3 complex subunit beta. (1065 aa)
SLC18A2Solute carrier family 18 member A2. (517 aa)
ITSN2Intersectin 2. (1697 aa)
SLC17A7Solute carrier family 17 member 7. (560 aa)
ITSN1Intersectin 1. (1719 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa)
CDK5Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (302 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (391 aa)
SH3GL2SH3 domain containing GRB2 like 2, endophilin A1. (357 aa)
THTyrosine hydroxylase. (549 aa)
UNC13AUnc-13 homolog A. (1520 aa)
GIT1GIT ArfGAP 1. (754 aa)
ENSMLEP00000020744Uncharacterized protein. (107 aa)
CPLX3Complexin 3. (158 aa)
UNC13BUncharacterized protein. (4338 aa)
STX1BSyntaxin 1B; Belongs to the syntaxin family. (245 aa)
AP3M2AP-3 complex subunit mu-2. (418 aa)
SLC17A6Solute carrier family 17 member 6. (582 aa)
PPFIA3PTPRF interacting protein alpha 3. (1160 aa)
NLGN2Neuroligin 2. (834 aa)
BTBD8BTB domain containing 8. (1411 aa)
ENSMLEP00000025021Uncharacterized protein. (1217 aa)
ENSMLEP00000025432B2-adapt-app_C domain-containing protein. (224 aa)
AMPHAmphiphysin. (677 aa)
SYNJ1Synaptojanin 1. (1614 aa)
CPLX2Complexin 2. (134 aa)
PLD2Phospholipase. (933 aa)
PRRT2Proline rich transmembrane protein 2. (347 aa)
ENSMLEP00000026939J domain-containing protein. (135 aa)
PICALMPhosphatidylinositol binding clathrin assembly protein. (674 aa)
BRSK1BR serine/threonine kinase 1. (763 aa)
SLC18A1Solute carrier family 18 member A1. (525 aa)
ACTBActin beta. (375 aa)
SNAP91Synaptosome associated protein 91. (872 aa)
STX2Syntaxin 2; Belongs to the syntaxin family. (278 aa)
STX4Syntaxin 4; Belongs to the syntaxin family. (297 aa)
SLC17A8Solute carrier family 17 member 8. (589 aa)
LRRC1Leucine rich repeat containing 1. (507 aa)
SNAP23Synaptosomal-associated protein; Belongs to the SNAP-25 family. (211 aa)
STX3Syntaxin 3; Belongs to the syntaxin family. (290 aa)
RIMS1Regulating synaptic membrane exocytosis 1. (1692 aa)
SNAP25Synaptosomal-associated protein; Belongs to the SNAP-25 family. (206 aa)
STON2Stonin-2; Adapter protein involved in endocytic machinery. Involved in the synaptic vesicle recycling. May facilitate clathrin-coated vesicle uncoating; Belongs to the Stoned B family. (920 aa)
CANXCalnexin. (592 aa)
GIT2GIT ArfGAP 2. (744 aa)
BLOC1S6Biogenesis of lysosome-related organelles complex 1 subunit 6; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. May play a role in intracellular vesicle trafficking, particular [...] (172 aa)
STX1ASyntaxin 1A; Belongs to the syntaxin family. (288 aa)
SYPSynaptophysin. (313 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (745 aa)
DNAJC5J domain-containing protein. (219 aa)
SYN1Synapsin I. (563 aa)
VAMP1Vesicle associated membrane protein 1. (118 aa)
KIAA1109KIAA1109. (5005 aa)
AP2B1AP complex subunit beta. (942 aa)
FCHO2FCH domain only 2. (815 aa)
RIMS3Regulating synaptic membrane exocytosis 3. (308 aa)
SCRIBScribble planar cell polarity protein. (1445 aa)
P2RX7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (595 aa)
DENND1ADENN domain containing 1A. (1007 aa)
CADPS2Calcium dependent secretion activator 2. (1242 aa)
GAKCyclin G associated kinase. (1311 aa)
NAPANSF attachment protein alpha. (295 aa)
CTBP2C-terminal binding protein 2. (985 aa)
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
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