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| | PLCL2 | Phosphoinositide phospholipase C. (1043 aa) |
| | OXTR | Oxytocin receptor; Receptor for oxytocin. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (389 aa) |
| | KDM1A | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (832 aa) |
| | IRF4 | Interferon regulatory factor 4. (379 aa) |
| | PER2 | Period circadian regulator 2. (1254 aa) |
| | LRRN4CL | LRRN4 C-terminal like. (238 aa) |
| | HSF1 | Heat shock transcription factor 1. (490 aa) |
| | DIO2 | Iodothyronine deiodinase; Responsible for the deiodination of T4 (3,5,3',5'- tetraiodothyronine). (145 aa) |
| | UCP2 | Uncoupling protein 2; Belongs to the mitochondrial carrier (TC 2.A.29) family. (309 aa) |
| | ACHE | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (631 aa) |
| | ACOT13 | Acyl-CoA thioesterase 13. (140 aa) |
| | ADRB2 | Adrenoceptor beta 2. (415 aa) |
| | GNAS | GNAS complex locus. (998 aa) |
| | LEPR | Leptin receptor. (1163 aa) |
| | SLC25A44 | Solute carrier family 25 member 44; Belongs to the mitochondrial carrier (TC 2.A.29) family. (322 aa) |
| | FFAR4 | Free fatty acid receptor 4. (376 aa) |
| | G0S2 | G0/G1 switch protein 2; Promotes apoptosis by binding to BCL2, hence preventing the formation of protective BCL2-BAX heterodimers. (103 aa) |
| | TRPM8 | Transient receptor potential cation channel subfamily M member 8. (1104 aa) |
| | IL13 | Interleukin 13. (146 aa) |
| | WNT10B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa) |
| | SLN | Uncharacterized protein. (31 aa) |
| | PRKAB1 | Protein kinase AMP-activated non-catalytic subunit beta 1. (270 aa) |
| | ATF4 | Activating transcription factor 4. (351 aa) |
| | PCTP | Phosphatidylcholine transfer protein. (219 aa) |
| | EHMT1 | Euchromatic histone lysine methyltransferase 1. (1255 aa) |
| | NR1H2 | Nuclear receptor subfamily 1 group H member 2. (463 aa) |
| | ZNF516 | Zinc finger protein 516. (1163 aa) |
| | GPR3 | G protein-coupled receptor 3; Belongs to the G-protein coupled receptor 1 family. (330 aa) |
| | HADH | Hydroxyacyl-CoA dehydrogenase. (331 aa) |
| | LNPEP | Leucyl and cystinyl aminopeptidase. (1027 aa) |
| | ACTN3 | Actinin alpha 3 (gene/pseudogene). (916 aa) |
| | PEMT | Phosphatidylethanolamine N-methyltransferase; Catalyzes the three sequential steps of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylethanolamine (PE) to phosphatidylmonomethylethanolamine (PMME), PMME to phosphatidyldimethylethanolamine (PDME), and PDME to phosphatidylcholine (PC); Belongs to the class VI-like SAM-binding methyltransferase superfamily. PEMT/PEM2 methyltransferase family. (236 aa) |
| | IL18R1 | Interleukin 18 receptor 1. (540 aa) |
| | DECR1 | 2,4-dienoyl-CoA reductase 1. (335 aa) |
| | ALPL | Alkaline phosphatase. (425 aa) |
| | RHEB | Ras homolog, mTORC1 binding. (181 aa) |
| | MFAP2 | Microfibril associated protein 2. (183 aa) |
| | CAV1 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (147 aa) |
| | ENSMLEP00000010153 | CSP domain-containing protein. (293 aa) |
| | NPR3 | Natriuretic peptide receptor 3. (541 aa) |
| | ACVR2B | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (521 aa) |
| | DHRS7B | Dehydrogenase/reductase 7B; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (325 aa) |
| | OGT | O-linked N-acetylglucosamine (GlcNAc) transferase. (1046 aa) |
| | APPL2 | Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2. (670 aa) |
| | UCP1 | Uncoupling protein 1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (307 aa) |
| | NOVA2 | NOVA alternative splicing regulator 2. (337 aa) |
| | DOCK7 | Dedicator of cytokinesis 7; Belongs to the DOCK family. (2048 aa) |
| | ARRDC3 | Arrestin domain containing 3. (414 aa) |
| | ELOVL6 | Elongation of very long chain fatty acids protein 6; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degre [...] (265 aa) |
| | JAK2 | Tyrosine-protein kinase. (1139 aa) |
| | TLR4 | Toll like receptor 4; Belongs to the Toll-like receptor family. (843 aa) |
| | CD36 | CD36 molecule; Belongs to the CD36 family. (472 aa) |
| | SIRT6 | Sirtuin 6. (355 aa) |
| | ALMS1 | ALMS1 centrosome and basal body associated protein. (4174 aa) |
| | MAP2K6 | Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (335 aa) |
| | GADD45G | Growth arrest and DNA damage inducible gamma. (159 aa) |
| | FLCN | Folliculin. (515 aa) |
| | IL4R | Interleukin 4 receptor. (819 aa) |
| | PGAM5 | Uncharacterized protein. (140 aa) |
| | ADIPOR2 | Adiponectin receptor 2. (386 aa) |
| | ACOT11 | Acyl-CoA thioesterase 11. (595 aa) |
| | FABP5 | FABP domain-containing protein; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (135 aa) |
| | FH | Fumarate hydratase. (510 aa) |
| | IL18 | Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (193 aa) |
| | ADIPOQ | Adiponectin, C1Q and collagen domain containing. (249 aa) |
| | TLE3 | TLE family member 3, transcriptional corepressor. (782 aa) |
| | PRDM16 | PR/SET domain 16. (1148 aa) |
| | DBH | Dopamine beta-hydroxylase. (620 aa) |
| | PPARGC1A | PPARG coactivator 1 alpha. (798 aa) |
| | DDIT3 | DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (169 aa) |
| | ABHD6 | Abhydrolase domain containing 6. (337 aa) |
| | NOTCH1 | Notch receptor 1. (2076 aa) |
| | ENSMLEP00000020563 | Uncharacterized protein; Belongs to the fatty acid desaturase type 1 family. (346 aa) |
| | IP6K1 | Kinase; Belongs to the inositol phosphokinase (IPK) family. (441 aa) |
| | RB1 | RB transcriptional corepressor 1. (891 aa) |
| | LCN2 | Lipocalin 2; Belongs to the calycin superfamily. Lipocalin family. (200 aa) |
| | EBF2 | EBF transcription factor 2. (575 aa) |
| | TRPV2 | Transient receptor potential cation channel subfamily V member 2; Belongs to the transient receptor (TC 1.A.4) family. (764 aa) |
| | THRA | Thyroid hormone receptor alpha. (607 aa) |
| | LOC105548340 | Uncharacterized protein. (246 aa) |
| | IGF1R | Tyrosine-protein kinase receptor. (1281 aa) |
| | FOXC2 | Forkhead box C2. (254 aa) |
| | NR1D1 | Nuclear receptor subfamily 1 group D member 1. (613 aa) |
| | CNOT3 | CCR4-NOT transcription complex subunit 3. (735 aa) |
| | ENSMLEP00000025294 | Uncharacterized protein. (109 aa) |
| | KDM3A | Lysine demethylase 3A. (1321 aa) |
| | LPIN1 | Lipin 1. (974 aa) |
| | TFE3 | Transcription factor binding to IGHM enhancer 3. (575 aa) |
| | BSCL2 | BSCL2 lipid droplet biogenesis associated, seipin. (466 aa) |
| | MFN2 | Mitofusin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (746 aa) |
| | PTH2R | Parathyroid hormone 2 receptor; Belongs to the G-protein coupled receptor 2 family. (550 aa) |
| | STK11 | Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (433 aa) |
| | OXT | Oxytocin/neurophysin I prepropeptide; Belongs to the vasopressin/oxytocin family. (125 aa) |
| | PDGFC | Platelet derived growth factor C; Belongs to the PDGF/VEGF growth factor family. (345 aa) |
| | EPAS1 | Endothelial PAS domain protein 1. (869 aa) |
| | KDM6B | Lysine demethylase 6B. (1669 aa) |
| | STAT6 | Signal transducer and activator of transcription. (847 aa) |
| | ADAMTS5 | ADAM metallopeptidase with thrombospondin type 1 motif 5. (761 aa) |
| | SCD | Uncharacterized protein; Belongs to the fatty acid desaturase type 1 family. (359 aa) |
| | GHRL | Ghrelin and obestatin prepropeptide. (117 aa) |
| | LGR4 | Leucine rich repeat containing G protein-coupled receptor 4. (940 aa) |
| | FGF21 | Fibroblast growth factor 21; Belongs to the heparin-binding growth factors family. (174 aa) |
| | YBX2 | Y-box binding protein 2. (323 aa) |
| | OMA1 | OMA1 zinc metallopeptidase. (524 aa) |
| | LAMA4 | Laminin subunit alpha 4. (1823 aa) |
| | ARNTL | Aryl hydrocarbon receptor nuclear translocator like. (628 aa) |
| | PRLR | Prolactin receptor; This is a receptor for the anterior pituitary hormone prolactin. (619 aa) |
| | DYNC1H1 | Dynein cytoplasmic 1 heavy chain 1. (4513 aa) |
| | SYK | Tyrosine-protein kinase. (618 aa) |
| | IL15 | Interleukin; Belongs to the IL-15/IL-21 family. (162 aa) |
| | ADIPOR1 | Adiponectin receptor 1. (375 aa) |
| | ZBTB7B | Zinc finger and BTB domain containing 7B. (573 aa) |
| | APC | APC regulator of WNT signaling pathway. (2806 aa) |
| | PPARGC1B | PPARG coactivator 1 beta. (997 aa) |
| | ADCYAP1 | Adenylate cyclase activating polypeptide 1. (176 aa) |
| | PRKAB2 | Protein kinase AMP-activated non-catalytic subunit beta 2. (272 aa) |
| | ACSL1 | Acyl-CoA synthetase long chain family member 1. (698 aa) |
| | ENSMLEP00000034447 | Homeobox domain-containing protein. (167 aa) |
| | PWWP2B | Uncharacterized protein. (281 aa) |
| | ZNF423 | Zinc finger protein 423. (1308 aa) |
| | CIDEA | Cell death inducing DFFA like effector a. (222 aa) |
| | LEP | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa) |
| | HOXC10 | Homeobox C10. (342 aa) |
| | GRB10 | Growth factor receptor bound protein 10. (593 aa) |
| | ADAM17 | ADAM metallopeptidase domain 17. (824 aa) |
| | PLCL1 | Phosphoinositide phospholipase C. (1018 aa) |
| | ELOVL3 | Elongation of very long chain fatty acids protein 3; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precurs [...] (270 aa) |
| | ID1 | Inhibitor of DNA binding 1, HLH protein. (154 aa) |
| | PLAC8 | Placenta associated 8. (113 aa) |
| | KSR2 | Kinase suppressor of ras 2. (950 aa) |
| | FABP4 | Fatty acid binding protein 4; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (132 aa) |
| | TSHR | Thyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (764 aa) |
| | NR1H3 | Nuclear receptor subfamily 1 group H member 3. (428 aa) |
