STRINGSTRING
CRY2 CRY2 CRHBP CRHBP F2R F2R ENSMLEP00000019778 ENSMLEP00000019778 SYT11 SYT11 ENSMLEP00000020342 ENSMLEP00000020342 NOTCH1 NOTCH1 ACVR1C ACVR1C ENSMLEP00000021360 ENSMLEP00000021360 ADRA2A ADRA2A GABBR1 GABBR1 ENSMLEP00000022792 ENSMLEP00000022792 RSAD2 RSAD2 FMR1 FMR1 ENSMLEP00000024563 ENSMLEP00000024563 VAMP8 VAMP8 FKBP1B FKBP1B ENSMLEP00000025582 ENSMLEP00000025582 FAM3D FAM3D CHGA CHGA ENSMLEP00000026510 ENSMLEP00000026510 CRY1 CRY1 ENSMLEP00000028290 ENSMLEP00000028290 ENSMLEP00000028396 ENSMLEP00000028396 ANXA1 ANXA1 GHRL GHRL MAOB MAOB SMCR8 SMCR8 TACR2 TACR2 ENSMLEP00000029949 ENSMLEP00000029949 SYTL4 SYTL4 STXBP5L STXBP5L ENSMLEP00000031001 ENSMLEP00000031001 WDR41 WDR41 SREBF1 SREBF1 RAB11FIP1 RAB11FIP1 MTNR1B MTNR1B NDUFAF2 NDUFAF2 NPVF NPVF JAGN1 JAGN1 RAB7A RAB7A STXBP3 STXBP3 LEP LEP ACSL4 ACSL4 BRAF BRAF ADRA2C ADRA2C TNFRSF1A TNFRSF1A ENSMLEP00000035415 ENSMLEP00000035415 ENSMLEP00000035626 ENSMLEP00000035626 RAB11FIP3 RAB11FIP3 BCR BCR CARTPT CARTPT SERGEF SERGEF PRKN PRKN SRCIN1 SRCIN1 PNKD PNKD OSM OSM PIM3 PIM3 LOC105542977 LOC105542977 TNFRSF1B TNFRSF1B INHA INHA MIDN MIDN NCKAP1L NCKAP1L SIRT4 SIRT4 DRD2 DRD2 NR1H3 NR1H3 RABGEF1 RABGEF1 NF1 NF1 P2RY1 P2RY1 ENSMLEP00000005644 ENSMLEP00000005644 TSPO TSPO TRH TRH CRH CRH INHBA INHBA FFAR4 FFAR4 NPY5R NPY5R ERP29 ERP29 HTR1B HTR1B ABAT ABAT VSNL1 VSNL1 LOC105554888 LOC105554888 REST REST LOC105541640 LOC105541640 KCNJ11 KCNJ11 ABCC8 ABCC8 KLF7 KLF7 NMB NMB IL13RA2 IL13RA2 ADIPOQ ADIPOQ RAB33B RAB33B RHBDF2 RHBDF2 IL12A IL12A SYT4 SYT4 SFRP1 SFRP1 ENSMLEP00000015404 ENSMLEP00000015404 ENSMLEP00000014987 ENSMLEP00000014987 ATP9A ATP9A CCN3 CCN3 DPH3 DPH3 GHSR GHSR RAB11FIP5 RAB11FIP5 PFKL PFKL ENSMLEP00000012301 ENSMLEP00000012301 ADTRP ADTRP ENSMLEP00000012128 ENSMLEP00000012128 IL1RAPL1 IL1RAPL1 C9orf72 C9orf72 OPRM1 OPRM1 DRD3 DRD3 LIF LIF CBARP CBARP IRS1 IRS1 PPP3CA PPP3CA PSMD9 PSMD9 CD84 CD84 KALRN KALRN LOC105535298 LOC105535298 RAP1A RAP1A LOC105534357 LOC105534357 ASIC1 ASIC1 HADH HADH RHBDF1 RHBDF1 ADRA2B ADRA2B HRH3 HRH3 FGF23 FGF23 PTPN11 PTPN11
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CRY2Cryptochrome circadian regulator 2. (614 aa)
CRHBPCorticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family. (322 aa)
F2RCoagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family. (425 aa)
ENSMLEP00000019778IGc1 domain-containing protein; Belongs to the MHC class I family. (327 aa)
SYT11Synaptotagmin 11. (431 aa)
ENSMLEP00000020342Uncharacterized protein. (69 aa)
NOTCH1Notch receptor 1. (2076 aa)
ACVR1CReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (493 aa)
ENSMLEP00000021360Uncharacterized protein. (128 aa)
ADRA2AAdrenoceptor alpha 2A. (310 aa)
GABBR1Gamma-aminobutyric acid type B receptor subunit 1. (966 aa)
ENSMLEP00000022792V-SNARE coiled-coil homology domain-containing protein. (109 aa)
RSAD2Radical S-adenosyl methionine domain containing 2. (360 aa)
FMR1Fragile X mental retardation 1. (632 aa)
ENSMLEP00000024563A20-type domain-containing protein. (100 aa)
VAMP8Vesicle associated membrane protein 8. (100 aa)
FKBP1BPeptidylprolyl isomerase. (95 aa)
ENSMLEP00000025582Uncharacterized protein. (230 aa)
FAM3DFamily with sequence similarity 3 member D. (224 aa)
CHGAChromogranin A. (457 aa)
ENSMLEP00000026510Ig-like domain-containing protein; Belongs to the MHC class I family. (301 aa)
CRY1Cryptochrome circadian regulator 1. (586 aa)
ENSMLEP00000028290Uncharacterized protein. (441 aa)
ENSMLEP00000028396IGc1 domain-containing protein. (205 aa)
ANXA1Annexin. (346 aa)
GHRLGhrelin and obestatin prepropeptide. (117 aa)
MAOBAmine oxidase. (520 aa)
SMCR8SMCR8-C9orf72 complex subunit. (936 aa)
TACR2Tachykinin receptor 2; Belongs to the G-protein coupled receptor 1 family. (398 aa)
ENSMLEP00000029949Uncharacterized protein. (265 aa)
SYTL4Synaptotagmin like 4. (670 aa)
STXBP5LSyntaxin binding protein 5 like. (1186 aa)
ENSMLEP00000031001Ig-like domain-containing protein; Belongs to the MHC class I family. (333 aa)
WDR41WD repeat domain 41. (459 aa)
SREBF1Sterol regulatory element binding transcription factor 1. (1124 aa)
RAB11FIP1Uncharacterized protein. (649 aa)
MTNR1BMelatonin receptor 1B; Belongs to the G-protein coupled receptor 1 family. (362 aa)
NDUFAF2NADH:ubiquinone oxidoreductase complex assembly factor 2. (169 aa)
NPVFNeuropeptide VF precursor. (196 aa)
JAGN1Jagunal homolog 1. (183 aa)
RAB7ARAB7A, member RAS oncogene family. (207 aa)
STXBP3Syntaxin binding protein 3; Belongs to the STXBP/unc-18/SEC1 family. (592 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
ACSL4Acyl-CoA synthetase long chain family member 4. (670 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (745 aa)
ADRA2CAdrenoceptor alpha 2C. (302 aa)
TNFRSF1ATNF receptor superfamily member 1A. (455 aa)
ENSMLEP00000035415Uncharacterized protein. (519 aa)
ENSMLEP00000035626Ig-like domain-containing protein; Belongs to the MHC class I family. (313 aa)
RAB11FIP3RAB11 family interacting protein 3. (443 aa)
BCRBCR activator of RhoGEF and GTPase. (1075 aa)
CARTPTCART prepropeptide. (116 aa)
SERGEFSecretion regulating guanine nucleotide exchange factor. (458 aa)
PRKNUbiquitin-like domain-containing protein. (368 aa)
SRCIN1SRC kinase signaling inhibitor 1. (1281 aa)
PNKDPNKD metallo-beta-lactamase domain containing. (385 aa)
OSMOncostatin M. (252 aa)
PIM3Pim-3 proto-oncogene, serine/threonine kinase. (208 aa)
LOC105542977Uncharacterized protein. (304 aa)
TNFRSF1BTNF receptor superfamily member 1B. (462 aa)
INHAInhibin alpha chain; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition; Belongs to the TGF-beta family. (366 aa)
MIDNMidnolin. (391 aa)
NCKAP1LNCK associated protein 1 like. (1056 aa)
SIRT4NAD-dependent protein lipoamidase sirtuin-4, mitochondrial; Acts as NAD-dependent protein lipoamidase, ADP-ribosyl transferase and deacetylase. Catalyzes more efficiently removal of lipoyl- and biotinyl- than acetyl-lysine modifications. Inhibits the pyruvate dehydrogenase complex (PDH) activity via the enzymatic hydrolysis of the lipoamide cofactor from the E2 component, DLAT, in a phosphorylation-independent manner. Catalyzes the transfer of ADP- ribosyl groups onto target proteins, including mitochondrial GLUD1, inhibiting GLUD1 enzyme activity. Acts as a negative regulator of mitoc [...] (314 aa)
DRD2Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (443 aa)
NR1H3Nuclear receptor subfamily 1 group H member 3. (428 aa)
RABGEF1Uncharacterized protein. (337 aa)
NF1Neurofibromin 1. (2839 aa)
P2RY1Purinergic receptor P2Y1; Belongs to the G-protein coupled receptor 1 family. (373 aa)
ENSMLEP00000005644Ig-like domain-containing protein; Belongs to the MHC class I family. (216 aa)
TSPOTranslocator protein. (169 aa)
TRHPro-thyrotropin-releasing hormone; Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems. (241 aa)
CRHCorticotropin releasing hormone. (196 aa)
INHBAInhibin subunit beta A. (426 aa)
FFAR4Free fatty acid receptor 4. (376 aa)
NPY5RNeuropeptide Y receptor Y5. (445 aa)
ERP29Endoplasmic reticulum resident protein 29; Does not seem to be a disulfide isomerase. (261 aa)
HTR1B5-hydroxytryptamine receptor 1B. (390 aa)
ABAT4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (516 aa)
VSNL1Visinin like 1. (191 aa)
LOC105554888Endoplasmic reticulum resident protein 29; Does not seem to be a disulfide isomerase. (261 aa)
RESTRE1 silencing transcription factor. (1095 aa)
LOC105541640Uncharacterized protein. (526 aa)
KCNJ11Potassium voltage-gated channel subfamily J member 11. (390 aa)
ABCC8ATP binding cassette subfamily C member 8. (1582 aa)
KLF7Kruppel like factor 7. (302 aa)
NMBNeuromedin B. (153 aa)
IL13RA2Interleukin 13 receptor subunit alpha 2. (380 aa)
ADIPOQAdiponectin, C1Q and collagen domain containing. (249 aa)
RAB33BRAB33B, member RAS oncogene family. (229 aa)
RHBDF2Rhomboid 5 homolog 2. (856 aa)
IL12AInterleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (253 aa)
SYT4Synaptotagmin 4. (425 aa)
SFRP1Secreted frizzled related protein 1. (206 aa)
ENSMLEP00000015404Fork-head domain-containing protein. (531 aa)
ENSMLEP00000014987IGc1 domain-containing protein; Belongs to the MHC class I family. (327 aa)
ATP9APhospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1025 aa)
CCN3Cellular communication network factor 3. (366 aa)
DPH3Diphthamide biosynthesis 3. (82 aa)
GHSRGrowth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family. (366 aa)
RAB11FIP5FIP-RBD domain-containing protein. (1218 aa)
PFKLATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (779 aa)
ENSMLEP00000012301Protein kinase domain-containing protein. (294 aa)
ADTRPAndrogen dependent TFPI regulating protein. (248 aa)
ENSMLEP00000012128Uncharacterized protein. (234 aa)
IL1RAPL1Interleukin 1 receptor accessory protein like 1. (437 aa)
C9orf72C9orf72-SMCR8 complex subunit. (481 aa)
OPRM1Opioid receptor mu 1; Belongs to the G-protein coupled receptor 1 family. (485 aa)
DRD3Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family. (400 aa)
LIFLIF interleukin 6 family cytokine. (202 aa)
CBARPCACN subunit beta associated regulatory protein. (444 aa)
IRS1Insulin receptor substrate 1. (1242 aa)
PPP3CASerine/threonine-protein phosphatase. (501 aa)
PSMD9PDZ domain-containing protein. (223 aa)
CD84CD84 molecule. (339 aa)
KALRNKalirin RhoGEF kinase. (2954 aa)
LOC105535298Ig-like domain-containing protein; Belongs to the MHC class I family. (345 aa)
RAP1ARAP1A, member of RAS oncogene family. (184 aa)
LOC105534357RBR-type E3 ubiquitin transferase. (77 aa)
ASIC1Acid sensing ion channel subunit 1; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (574 aa)
HADHHydroxyacyl-CoA dehydrogenase. (331 aa)
RHBDF1Rhomboid 5 homolog 1. (859 aa)
ADRA2BAdrenoceptor alpha 2B. (447 aa)
HRH3Histamine receptor H3; Belongs to the G-protein coupled receptor 1 family. (361 aa)
FGF23Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (251 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (656 aa)
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
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