STRINGSTRING
UNC13C UNC13C ENSMLEP00000017246 ENSMLEP00000017246 CAPN9 CAPN9 ENSMLEP00000017158 ENSMLEP00000017158 WAS WAS PHLDB2 PHLDB2 LANCL3 LANCL3 STIM1 STIM1 PRKCZ PRKCZ CTBP2 CTBP2 CNKSR1 CNKSR1 RASSF4 RASSF4 HCLS1 HCLS1 SEPTIN5 SEPTIN5 SPIRE2 SPIRE2 ENSMLEP00000009668 ENSMLEP00000009668 LLGL1 LLGL1 ERC1 ERC1 CASR CASR KRT19 KRT19 ACTN3 ACTN3 TDO2 TDO2 UNC13A UNC13A SSPN SSPN ENSMLEP00000021441 ENSMLEP00000021441 AKT2 AKT2 CALB1 CALB1 ENSMLEP00000022318 ENSMLEP00000022318 CLTA CLTA UNC13B UNC13B ENSMLEP00000022792 ENSMLEP00000022792 INSC INSC ARV1 ARV1 ANK1 ANK1 SEPTIN10 SEPTIN10 NEDD9 NEDD9 FNBP1 FNBP1 PPFIA3 PPFIA3 NAP1L3 NAP1L3 SPRR4 SPRR4 SPTB SPTB EZR EZR LOC105539461 LOC105539461 JTB JTB SEPTIN11 SEPTIN11 LOC105543987 LOC105543987 PHLDB1 PHLDB1 CLTB CLTB EXOC3L4 EXOC3L4 SPTAN1 SPTAN1 RIMS3 RIMS3 DLG4 DLG4 RIMBP2 RIMBP2 C2CD2L C2CD2L EXOC6B EXOC6B KNCN KNCN MYH9 MYH9 SEPTIN1 SEPTIN1 FNBP1L FNBP1L SPATA3 SPATA3 NIM1K NIM1K CTSZ CTSZ WASL WASL RHOA RHOA HAAO HAAO TRIP10 TRIP10 EPB41L2 EPB41L2 ACTN2 ACTN2 OCM2 OCM2 SEPTIN3 SEPTIN3 GPSM2 GPSM2 ENSMLEP00000025021 ENSMLEP00000025021 RTKN RTKN MKLN1 MKLN1 UTRN UTRN OSBPL8 OSBPL8 TBC1D10B TBC1D10B C2CD5 C2CD5 ENSMLEP00000032851 ENSMLEP00000032851 EXOC5 EXOC5 ACTN1 ACTN1 ACTR1A ACTR1A DLC1 DLC1 PVALB PVALB ENSMLEP00000034218 ENSMLEP00000034218 PLEKHH2 PLEKHH2 KHDC3L KHDC3L CTTN CTTN MYADM MYADM CFL2 CFL2 FGF1 FGF1 GPX3 GPX3 PXN PXN CALD1 CALD1 PFN4 PFN4 CYTIP CYTIP EPB42 EPB42 EXOC7 EXOC7 EXOC1L EXOC1L ENSMLEP00000003309 ENSMLEP00000003309 LOC105542612 LOC105542612 PLS1 PLS1 MELK MELK PHLDB3 PHLDB3 EPB41 EPB41 ARL6IP6 ARL6IP6 SEPTIN12 SEPTIN12 DMD DMD NSMF NSMF CD302 CD302 LOC105532356 LOC105532356 MAPRE1 MAPRE1 ARFIP2 ARFIP2 EXOC8 EXOC8 SPTBN1 SPTBN1 OOEP OOEP LOC105555622 LOC105555622 SEPTIN4 SEPTIN4 EXOC3L1 EXOC3L1 FGFR2 FGFR2 SEPTIN14 SEPTIN14 AKAP13 AKAP13 PPP1R36 PPP1R36 ANLN ANLN SAPCD2 SAPCD2 DBN1 DBN1 ENSMLEP00000015112 ENSMLEP00000015112 ENSMLEP00000014628 ENSMLEP00000014628 SPIRE1 SPIRE1 PTK2B PTK2B FER FER EXOC1 EXOC1 EPS8 EPS8 ECT2 ECT2 EXOC6 EXOC6 FLNB FLNB SEPTIN9 SEPTIN9 EXOC4 EXOC4 SEPTIN6 SEPTIN6 MYO5B MYO5B EXOC3 EXOC3 ERC2 ERC2 TRPC4 TRPC4 GSN GSN NUMA1 NUMA1 FMNL1 FMNL1 SHPK SHPK LANCL2 LANCL2 SPINK5 SPINK5 GIPC1 GIPC1 ANK3 ANK3 CIB2 CIB2 PPP1R9A PPP1R9A MYH10 MYH10 SELE SELE KYNU KYNU EXOC3L2 EXOC3L2 TNFAIP2 TNFAIP2 CLASP1 CLASP1 BFSP1 BFSP1 RIMS1 RIMS1 ENSMLEP00000020342 ENSMLEP00000020342 MYO9B MYO9B SPTA1 SPTA1 SLC4A1 SLC4A1 SLA SLA KMO KMO GYS2 GYS2 EXOC2 EXOC2 NEDD4 NEDD4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
UNC13CUnc-13 homolog C. (2186 aa)
ENSMLEP00000017246Uncharacterized protein. (149 aa)
CAPN9Calpain 9; Belongs to the peptidase C2 family. (701 aa)
ENSMLEP00000017158Uncharacterized protein. (316 aa)
WASWASP actin nucleation promoting factor. (503 aa)
PHLDB2Pleckstrin homology like domain family B member 2. (1254 aa)
LANCL3LanC like 3. (414 aa)
STIM1Stromal interaction molecule 1. (790 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (596 aa)
CTBP2C-terminal binding protein 2. (985 aa)
CNKSR1Connector enhancer of kinase suppressor of Ras 1. (720 aa)
RASSF4Ras association domain family member 4. (321 aa)
HCLS1Hematopoietic cell-specific Lyn substrate 1. (476 aa)
SEPTIN5Septin 5; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (365 aa)
SPIRE2Spire type actin nucleation factor 2. (585 aa)
ENSMLEP00000009668Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (383 aa)
LLGL1LLGL scribble cell polarity complex component 1. (1075 aa)
ERC1ELKS/RAB6-interacting/CAST family member 1. (1120 aa)
CASRCalcium sensing receptor. (1088 aa)
KRT19Keratin 19; Belongs to the intermediate filament family. (397 aa)
ACTN3Actinin alpha 3 (gene/pseudogene). (916 aa)
TDO2Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. (406 aa)
UNC13AUnc-13 homolog A. (1520 aa)
SSPNSarcospan. (243 aa)
ENSMLEP00000021441FERM domain-containing protein. (478 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
CALB1Calbindin 1. (261 aa)
ENSMLEP00000022318PDZ domain-containing protein. (197 aa)
CLTAClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (248 aa)
UNC13BUncharacterized protein. (4338 aa)
ENSMLEP00000022792V-SNARE coiled-coil homology domain-containing protein. (109 aa)
INSCINSC spindle orientation adaptor protein. (579 aa)
ARV1ARV1 homolog, fatty acid homeostasis modulator. (271 aa)
ANK1Ankyrin 1. (1872 aa)
SEPTIN10Septin 10; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (541 aa)
NEDD9Neural precursor cell expressed, developmentally down-regulated 9. (820 aa)
FNBP1Formin binding protein 1. (523 aa)
PPFIA3PTPRF interacting protein alpha 3. (1160 aa)
NAP1L3Nucleosome assembly protein 1 like 3; Belongs to the nucleosome assembly protein (NAP) family. (507 aa)
SPRR4Small proline rich protein 4. (80 aa)
SPTBSpectrin beta chain; Belongs to the spectrin family. (2319 aa)
EZREzrin. (588 aa)
LOC105539461Cytoplasmic linker associated protein 2. (702 aa)
JTBJumping translocation breakpoint. (146 aa)
SEPTIN11Septin 11; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (439 aa)
LOC105543987Uncharacterized protein. (240 aa)
PHLDB1Pleckstrin homology like domain family B member 1. (1387 aa)
CLTBClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (203 aa)
EXOC3L4Exocyst complex component 3 like 4. (722 aa)
SPTAN1Spectrin alpha, non-erythrocytic 1. (2414 aa)
RIMS3Regulating synaptic membrane exocytosis 3. (308 aa)
DLG4Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family. (767 aa)
RIMBP2RIMS binding protein 2. (1052 aa)
C2CD2LC2CD2 like. (707 aa)
EXOC6BExocyst complex component; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. (815 aa)
KNCNKinocilin. (124 aa)
MYH9Myosin heavy chain 9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1942 aa)
SEPTIN1Septin 1; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (380 aa)
FNBP1LFormin binding protein 1 like. (605 aa)
SPATA3Spermatogenesis associated 3. (192 aa)
NIM1KNIM1 serine/threonine protein kinase; Belongs to the protein kinase superfamily. (436 aa)
CTSZCathepsin Z; Belongs to the peptidase C1 family. (367 aa)
WASLWASP like actin nucleation promoting factor. (503 aa)
RHOARas homolog family member A. (193 aa)
HAAO3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate; Belongs to the 3-HAO family. (286 aa)
TRIP10Thyroid hormone receptor interactor 10. (589 aa)
EPB41L2Erythrocyte membrane protein band 4.1 like 2. (998 aa)
ACTN2Actinin alpha 2. (873 aa)
OCM2Uncharacterized protein; Belongs to the parvalbumin family. (109 aa)
SEPTIN3Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (311 aa)
GPSM2G protein signaling modulator 2. (685 aa)
ENSMLEP00000025021Uncharacterized protein. (1217 aa)
RTKNRhotekin. (563 aa)
MKLN1Muskelin 1. (735 aa)
UTRNUtrophin. (2945 aa)
OSBPL8Oxysterol-binding protein; Belongs to the OSBP family. (889 aa)
TBC1D10BTBC1 domain family member 10B. (728 aa)
C2CD5C2 calcium dependent domain containing 5. (1084 aa)
ENSMLEP00000032851FH2 domain-containing protein. (198 aa)
EXOC5Exocyst complex component 5. (711 aa)
ACTN1Actinin alpha 1. (914 aa)
ACTR1AActin related protein 1A. (377 aa)
DLC1DLC1 Rho GTPase activating protein. (1504 aa)
PVALBParvalbumin; Belongs to the parvalbumin family. (110 aa)
ENSMLEP00000034218IF rod domain-containing protein; Belongs to the intermediate filament family. (383 aa)
PLEKHH2Pleckstrin homology, MyTH4 and FERM domain containing H2. (1493 aa)
KHDC3LKH domain containing 3 like, subcortical maternal complex member. (217 aa)
CTTNCortactin. (550 aa)
MYADMMyeloid associated differentiation marker. (322 aa)
CFL2Cofilin 2; Belongs to the actin-binding proteins ADF family. (166 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
GPX3Glutathione peroxidase; Belongs to the glutathione peroxidase family. (225 aa)
PXNPaxillin. (1079 aa)
CALD1Caldesmon 1. (793 aa)
PFN4Profilin; Belongs to the profilin family. (129 aa)
CYTIPCytohesin 1 interacting protein. (359 aa)
EPB42Erythrocyte membrane protein band 4.2. (529 aa)
EXOC7Exocyst complex component 7; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. (690 aa)
EXOC1LExocyst complex component 1 like. (172 aa)
ENSMLEP00000003309PDZ domain-containing protein. (442 aa)
LOC105542612Uncharacterized protein. (316 aa)
PLS1Plastin 1. (629 aa)
MELKNon-specific serine/threonine protein kinase. (651 aa)
PHLDB3Pleckstrin homology like domain family B member 3. (567 aa)
EPB41Erythrocyte membrane protein band 4.1. (848 aa)
ARL6IP6ADP ribosylation factor like GTPase 6 interacting protein 6. (226 aa)
SEPTIN12Septin 12; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (358 aa)
DMDZZ-type domain-containing protein. (635 aa)
NSMFNMDA receptor synaptonuclear signaling and neuronal migration factor. (485 aa)
CD302CD302 molecule. (209 aa)
LOC105532356C2 domain-containing protein. (285 aa)
MAPRE1Microtubule associated protein RP/EB family member 1. (269 aa)
ARFIP2ADP ribosylation factor interacting protein 2. (374 aa)
EXOC8Exocyst complex component 8. (727 aa)
SPTBN1Spectrin beta chain; Belongs to the spectrin family. (2366 aa)
OOEPOocyte expressed protein. (149 aa)
LOC105555622Uncharacterized protein. (3074 aa)
SEPTIN4Septin 4; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (985 aa)
EXOC3L1Exocyst complex component 3 like 1. (746 aa)
FGFR2Fibroblast growth factor receptor. (838 aa)
SEPTIN14Septin 14; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (295 aa)
AKAP13A-kinase anchoring protein 13. (2785 aa)
PPP1R36Protein phosphatase 1 regulatory subunit 36. (296 aa)
ANLNAnillin actin binding protein. (1127 aa)
SAPCD2Suppressor APC domain containing 2. (219 aa)
DBN1Drebrin 1. (688 aa)
ENSMLEP00000015112Uncharacterized protein. (51 aa)
ENSMLEP00000014628Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (430 aa)
SPIRE1Spire type actin nucleation factor 1. (643 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
FERTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa)
EXOC1Exocyst complex component 1. (901 aa)
EPS8Epidermal growth factor receptor pathway substrate 8. (822 aa)
ECT2Epithelial cell transforming 2. (917 aa)
EXOC6Exocyst complex component; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. (804 aa)
FLNBFilamin B. (2572 aa)
SEPTIN9Septin 9; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (612 aa)
EXOC4Uncharacterized protein. (444 aa)
SEPTIN6Septin 6; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (434 aa)
MYO5BUncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1841 aa)
EXOC3Exocyst complex component 3. (757 aa)
ERC2ELKS/RAB6-interacting/CAST family member 2. (957 aa)
TRPC4Transient receptor potential cation channel subfamily C member 4; Belongs to the transient receptor (TC 1.A.4) family. (982 aa)
GSNGelsolin. (787 aa)
NUMA1Nuclear mitotic apparatus protein 1. (2127 aa)
FMNL1Formin like 1. (1085 aa)
SHPKFGGY_N domain-containing protein. (427 aa)
LANCL2LanC like 2. (382 aa)
SPINK5Serine peptidase inhibitor, Kazal type 5. (1086 aa)
GIPC1GIPC PDZ domain containing family member 1. (333 aa)
ANK3Ankyrin 3. (4377 aa)
CIB2Calcium and integrin binding family member 2. (166 aa)
PPP1R9AProtein phosphatase 1 regulatory subunit 9A. (1371 aa)
MYH10Myosin heavy chain 10; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2007 aa)
SELESelectin E. (610 aa)
KYNUKynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. Has a preference for the L-3-hydroxy form. Also has cysteine-conjugate-beta-lyase activity. Belongs to the kynureninase family. (465 aa)
EXOC3L2Exocyst complex component 3 like 2. (704 aa)
TNFAIP2TNF alpha induced protein 2. (533 aa)
CLASP1Cytoplasmic linker associated protein 1. (1533 aa)
BFSP1Beaded filament structural protein 1. (625 aa)
RIMS1Regulating synaptic membrane exocytosis 1. (1692 aa)
ENSMLEP00000020342Uncharacterized protein. (69 aa)
MYO9BMyosin IXB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1906 aa)
SPTA1Spectrin alpha, erythrocytic 1. (2420 aa)
SLC4A1Anion exchange protein. (928 aa)
SLASrc like adaptor. (293 aa)
KMOKynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract. (469 aa)
GYS2Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan. (703 aa)
EXOC2Exocyst complex component 2; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family. (924 aa)
NEDD4NEDD4 E3 ubiquitin protein ligase. (1272 aa)
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
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