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SCN2A SCN2A KCNQ1 KCNQ1 KCND1 KCND1 KCNH7 KCNH7 RYR3 RYR3 HCN3 HCN3 KCND3 KCND3 TPCN2 TPCN2 KCNH5 KCNH5 KCNA7 KCNA7 CACNA1S CACNA1S HVCN1 HVCN1 CATSPER4 CATSPER4 KCNH6 KCNH6 KCNG1 KCNG1 TRPM3 TRPM3 CACNA1B CACNA1B TRPC1 TRPC1 CACNA1A CACNA1A KCNS1 KCNS1 CNGA1 CNGA1 KCNV1 KCNV1 SCN7A SCN7A KCNH3 KCNH3 RYR1 RYR1 SCN4A SCN4A KCNQ2 KCNQ2 CACNA1I CACNA1I KCNG4 KCNG4 SCN11A SCN11A TRPC6 TRPC6 KCNA6 KCNA6 TRPV5 TRPV5 TRPM1 TRPM1 CACNA1C CACNA1C SCN5A SCN5A KCNMA1 KCNMA1 TRPA1 TRPA1 KCNB2 KCNB2 TRPV4 TRPV4 TRPM6 TRPM6 NALCN NALCN ITPR3 ITPR3 KCNQ5 KCNQ5 TRPV2 TRPV2 CACNA1G CACNA1G CACNA1F CACNA1F KCNH1 KCNH1 HCN1 HCN1 CACNA1E CACNA1E TPCN1 TPCN1 CACNA1D CACNA1D TRPM7 TRPM7 TRPV3 TRPV3 KCNC1 KCNC1 TRPV1 TRPV1 KCNC4 KCNC4 HCN4 HCN4 SCN8A SCN8A TRPC3 TRPC3 TRPC7 TRPC7 KCNV2 KCNV2 KCNQ4 KCNQ4 KCND2 KCND2 KCNU1 KCNU1 TRPC4 TRPC4 TRPM5 TRPM5 SCN1A SCN1A TRPC5 TRPC5 ENSMLEP00000010338 ENSMLEP00000010338 KCNH8 KCNH8 SCN10A SCN10A CATSPER3 CATSPER3 RYR2 RYR2 ITPR1 ITPR1 LOC105537369 LOC105537369 KCNA3 KCNA3 KCNA5 KCNA5 SCN9A SCN9A CATSPER1 CATSPER1 ITPR2 ITPR2 KCNA10 KCNA10 KCNS3 KCNS3 TRPV6 TRPV6 CACNA1H CACNA1H TRPM8 TRPM8 CNGA4 CNGA4 KCNG3 KCNG3 KCNH4 KCNH4 CNGA3 CNGA3 KCNQ3 KCNQ3 TRPM2 TRPM2 KCNS2 KCNS2 SCN3A SCN3A KCNA1 KCNA1 KCNH2 KCNH2 CNGA2 CNGA2 KCNC2 KCNC2 KCNA2 KCNA2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SCN2ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2005 aa)
KCNQ1Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (592 aa)
KCND1Potassium voltage-gated channel subfamily D member 1; Belongs to the potassium channel family. (647 aa)
KCNH7Potassium voltage-gated channel subfamily H member 7. (1195 aa)
RYR3Ryanodine receptor 3. (4804 aa)
HCN3Hyperpolarization activated cyclic nucleotide gated potassium channel 3. (763 aa)
KCND3Potassium voltage-gated channel subfamily D member 3; Belongs to the potassium channel family. (655 aa)
TPCN2Two pore segment channel 2. (752 aa)
KCNH5Potassium voltage-gated channel subfamily H member 5. (988 aa)
KCNA7Potassium voltage-gated channel subfamily A member 7; Belongs to the potassium channel family. (401 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1846 aa)
HVCN1Hydrogen voltage gated channel 1. (273 aa)
CATSPER4Cation channel sperm associated 4. (484 aa)
KCNH6Potassium voltage-gated channel subfamily H member 6. (994 aa)
KCNG1Potassium voltage-gated channel modifier subfamily G member 1; Belongs to the potassium channel family. (491 aa)
TRPM3Transient receptor potential cation channel subfamily M member 3. (1711 aa)
CACNA1BCalcium voltage-gated channel subunit alpha1 B. (2001 aa)
TRPC1Transient receptor potential cation channel subfamily C member 1; Belongs to the transient receptor (TC 1.A.4) family. (809 aa)
CACNA1ACalcium voltage-gated channel subunit alpha1 A. (1985 aa)
KCNS1Potassium voltage-gated channel modifier subfamily S member 1; Belongs to the potassium channel family. (529 aa)
CNGA1Cyclic nucleotide gated channel subunit alpha 1. (759 aa)
KCNV1Potassium voltage-gated channel modifier subfamily V member 1; Belongs to the potassium channel family. (503 aa)
SCN7ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1681 aa)
KCNH3Potassium voltage-gated channel subfamily H member 3. (1210 aa)
RYR1Ryanodine receptor 1. (4628 aa)
SCN4ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1836 aa)
KCNQ2Potassium voltage-gated channel subfamily Q member 2; Belongs to the potassium channel family. (932 aa)
CACNA1IVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2080 aa)
KCNG4Potassium voltage-gated channel modifier subfamily G member 4; Belongs to the potassium channel family. (519 aa)
SCN11ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1796 aa)
TRPC6Transient receptor potential cation channel subfamily C member 6; Belongs to the transient receptor (TC 1.A.4) family. (931 aa)
KCNA6Potassium voltage-gated channel subfamily A member 6; Belongs to the potassium channel family. (531 aa)
TRPV5Transient receptor potential cation channel subfamily V member 5; Belongs to the transient receptor (TC 1.A.4) family. (729 aa)
TRPM1Transient receptor potential cation channel subfamily M member 1. (1642 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2169 aa)
SCN5ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1987 aa)
KCNMA1Potassium calcium-activated channel subfamily M alpha 1. (1264 aa)
TRPA1Transient receptor potential cation channel subfamily A member 1; Belongs to the transient receptor (TC 1.A.4) family. (1119 aa)
KCNB2Potassium voltage-gated channel subfamily B member 2; Belongs to the potassium channel family. (910 aa)
TRPV4Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (871 aa)
TRPM6Transient receptor potential cation channel subfamily M member 6. (2032 aa)
NALCNSodium leak channel, non-selective. (1759 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2675 aa)
KCNQ5Potassium voltage-gated channel subfamily Q member 5. (878 aa)
TRPV2Transient receptor potential cation channel subfamily V member 2; Belongs to the transient receptor (TC 1.A.4) family. (764 aa)
CACNA1GVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2360 aa)
CACNA1FVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1960 aa)
KCNH1Potassium voltage-gated channel subfamily H member 1. (989 aa)
HCN1Hyperpolarization activated cyclic nucleotide gated potassium channel 1. (748 aa)
CACNA1EVoltage-dependent R-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents. (2315 aa)
TPCN1Two pore segment channel 1. (888 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2181 aa)
TRPM7Transient receptor potential cation channel subfamily M member 7. (1846 aa)
TRPV3Transient receptor potential cation channel subfamily V member 3; Belongs to the transient receptor (TC 1.A.4) family. (794 aa)
KCNC1Potassium voltage-gated channel subfamily C member 1; Belongs to the potassium channel family. (585 aa)
TRPV1Transient receptor potential cation channel subfamily V member 1; Belongs to the transient receptor (TC 1.A.4) family. (850 aa)
KCNC4Potassium voltage-gated channel subfamily C member 4; Belongs to the potassium channel family. (632 aa)
HCN4Hyperpolarization activated cyclic nucleotide gated potassium channel 4. (1035 aa)
SCN8ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1980 aa)
TRPC3Transient receptor potential cation channel subfamily C member 3; Belongs to the transient receptor (TC 1.A.4) family. (849 aa)
TRPC7Transient receptor potential cation channel subfamily C member 7; Belongs to the transient receptor (TC 1.A.4) family. (863 aa)
KCNV2Potassium voltage-gated channel modifier subfamily V member 2; Belongs to the potassium channel family. (545 aa)
KCNQ4Potassium voltage-gated channel subfamily Q member 4; Belongs to the potassium channel family. (608 aa)
KCND2Potassium voltage-gated channel subfamily D member 2; Belongs to the potassium channel family. (630 aa)
KCNU1Potassium calcium-activated channel subfamily U member 1. (1153 aa)
TRPC4Transient receptor potential cation channel subfamily C member 4; Belongs to the transient receptor (TC 1.A.4) family. (982 aa)
TRPM5Transient receptor potential cation channel subfamily M member 5. (1081 aa)
SCN1ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1912 aa)
TRPC5Transient receptor potential cation channel subfamily C member 5; Belongs to the transient receptor (TC 1.A.4) family. (974 aa)
ENSMLEP00000010338Ion_trans domain-containing protein. (257 aa)
KCNH8Potassium voltage-gated channel subfamily H member 8. (959 aa)
SCN10ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1959 aa)
CATSPER3Cation channel sperm associated 3. (398 aa)
RYR2Ryanodine receptor 2. (4862 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2731 aa)
LOC105537369Ion_trans domain-containing protein. (472 aa)
KCNA3Potassium voltage-gated channel subfamily A member 3; Belongs to the potassium channel family. (575 aa)
KCNA5Potassium voltage-gated channel subfamily A member 5; Belongs to the potassium channel family. (605 aa)
SCN9ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1977 aa)
CATSPER1Cation channel sperm associated 1. (768 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2663 aa)
KCNA10Potassium voltage-gated channel subfamily A member 10; Belongs to the potassium channel family. (511 aa)
KCNS3Potassium voltage-gated channel modifier subfamily S member 3; Belongs to the potassium channel family. (491 aa)
TRPV6Transient receptor potential cation channel subfamily V member 6; Belongs to the transient receptor (TC 1.A.4) family. (770 aa)
CACNA1HCalcium voltage-gated channel subunit alpha1 H. (2170 aa)
TRPM8Transient receptor potential cation channel subfamily M member 8. (1104 aa)
CNGA4Cyclic nucleotide gated channel subunit alpha 4. (575 aa)
KCNG3Potassium voltage-gated channel modifier subfamily G member 3; Belongs to the potassium channel family. (288 aa)
KCNH4Potassium voltage-gated channel subfamily H member 4. (1006 aa)
CNGA3Cyclic nucleotide gated channel subunit alpha 3. (694 aa)
KCNQ3Potassium voltage-gated channel subfamily Q member 3; Belongs to the potassium channel family. (752 aa)
TRPM2Transient receptor potential cation channel subfamily M member 2. (1552 aa)
KCNS2Potassium voltage-gated channel modifier subfamily S member 2; Belongs to the potassium channel family. (477 aa)
SCN3ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2000 aa)
KCNA1Potassium voltage-gated channel subfamily A member 1; Belongs to the potassium channel family. (495 aa)
KCNH2Potassium voltage-gated channel subfamily H member 2. (991 aa)
CNGA2Cyclic nucleotide gated channel subunit alpha 2. (664 aa)
KCNC2Potassium voltage-gated channel subfamily C member 2; Belongs to the potassium channel family. (638 aa)
KCNA2Potassium voltage-gated channel subfamily A member 2; Belongs to the potassium channel family. (356 aa)
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
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