STRINGSTRING
CARD16 CARD16 NLRP11 NLRP11 UNC5CL UNC5CL EDARADD EDARADD CARD11 CARD11 PIDD1 PIDD1 ANK3 ANK3 MALT1 MALT1 MAVS MAVS CASP9 CASP9 EDAR EDAR BIRC3 BIRC3 CARD10 CARD10 TNFRSF1A TNFRSF1A UNC5C UNC5C NLRP10 NLRP10 NLRP12 NLRP12 FAS FAS NLRP4 NLRP4 FADD FADD TNFRSF11B TNFRSF11B CRADD CRADD UNC5B UNC5B CARD14 CARD14 UNC5A UNC5A NOD2 NOD2 NLRP8 NLRP8 NLRP9 NLRP9 IRAK2 IRAK2 RIPK2 RIPK2 APAF1 APAF1 AIM2 AIM2 BCL10 BCL10 CASP10 CASP10 CASP1 CASP1 CARD19 CARD19 ANK1 ANK1 BIRC2 BIRC2 NLRP14 NLRP14 NOD1 NOD1 TRADD TRADD NLRP3 NLRP3 IFI16 IFI16 THOC1 THOC1 IRAK3 IRAK3 CASP2 CASP2 DAPK1 DAPK1 PYHIN1 PYHIN1 ANK2 ANK2 CASP12 CASP12 NLRP7 NLRP7 CASP8 CASP8 MYD88 MYD88 CARD6 CARD6 LOC105534152 LOC105534152 IRAK4 IRAK4 MEFV MEFV LRRD1 LRRD1 DTHD1 DTHD1 ENSMLEP00000013258 ENSMLEP00000013258 NFKB1 NFKB1 LOC105534146 LOC105534146 NLRP6 NLRP6 UNC5D UNC5D NLRC4 NLRC4 DEDD2 DEDD2 DDX58 DDX58 ANKDD1B ANKDD1B CFLAR CFLAR CASP5 CASP5 CARD9 CARD9 NLRP1 NLRP1 PYDC1 PYDC1 CASP4 CASP4 IGFLR1 IGFLR1 MNDA MNDA TNFRSF25 TNFRSF25 ANKDD1A ANKDD1A DEDD DEDD NLRP5 NLRP5 TNFRSF21 TNFRSF21 RIPK1 RIPK1 NFKB2 NFKB2 PYCARD PYCARD TNFRSF10A TNFRSF10A CARD18 CARD18 PYDC2 PYDC2 NGFR NGFR TNFRSF10B TNFRSF10B PEA15 PEA15 IFIH1 IFIH1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CARD16Caspase recruitment domain family member 16. (196 aa)
NLRP11NLR family pyrin domain containing 11. (1034 aa)
UNC5CLUnc-5 family C-terminal like. (518 aa)
EDARADDEDAR associated death domain. (195 aa)
CARD11Caspase recruitment domain family member 11. (1154 aa)
PIDD1P53-induced death domain protein 1. (910 aa)
ANK3Ankyrin 3. (4377 aa)
MALT1MALT1 paracaspase. (778 aa)
MAVSMitochondrial antiviral signaling protein. (541 aa)
CASP9Caspase 9; Belongs to the peptidase C14A family. (400 aa)
EDAREctodysplasin A receptor. (437 aa)
BIRC3Baculoviral IAP repeat containing 3. (604 aa)
CARD10Caspase recruitment domain family member 10. (1019 aa)
TNFRSF1ATNF receptor superfamily member 1A. (455 aa)
UNC5CUnc-5 netrin receptor C. (931 aa)
NLRP10NLR family pyrin domain containing 10. (656 aa)
NLRP12NLR family pyrin domain containing 12. (1031 aa)
FASFas cell surface death receptor. (331 aa)
NLRP4NLR family pyrin domain containing 4. (937 aa)
FADDFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa)
TNFRSF11BTNF receptor superfamily member 11b. (428 aa)
CRADDCASP2 and RIPK1 domain containing adaptor with death domain. (199 aa)
UNC5BUnc-5 netrin receptor B. (945 aa)
CARD14Caspase recruitment domain family member 14. (989 aa)
UNC5AUnc-5 netrin receptor A. (896 aa)
NOD2Nucleotide binding oligomerization domain containing 2. (1012 aa)
NLRP8NLR family pyrin domain containing 8. (1052 aa)
NLRP9NLR family pyrin domain containing 9. (873 aa)
IRAK2Interleukin 1 receptor associated kinase 2. (625 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (540 aa)
APAF1Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1248 aa)
AIM2Absent in melanoma 2. (343 aa)
BCL10BCL10 immune signaling adaptor. (312 aa)
CASP10Caspase 10; Belongs to the peptidase C14A family. (519 aa)
CASP1Caspase 1; Belongs to the peptidase C14A family. (404 aa)
CARD19Caspase recruitment domain family member 19. (307 aa)
ANK1Ankyrin 1. (1872 aa)
BIRC2Baculoviral IAP repeat containing 2. (618 aa)
NLRP14NLR family pyrin domain containing 14. (1092 aa)
NOD1Nucleotide binding oligomerization domain containing 1. (961 aa)
TRADDTNFRSF1A associated via death domain. (308 aa)
NLRP3NLR family pyrin domain containing 3. (1035 aa)
IFI16Interferon gamma inducible protein 16. (729 aa)
THOC1THO complex 1. (660 aa)
IRAK3Interleukin 1 receptor associated kinase 3. (582 aa)
CASP2Caspase 2; Belongs to the peptidase C14A family. (452 aa)
DAPK1Death associated protein kinase 1. (1430 aa)
PYHIN1Pyrin and HIN domain family member 1. (492 aa)
ANK2Ankyrin 2. (3938 aa)
CASP12Caspase 12 (gene/pseudogene); Belongs to the peptidase C14A family. (421 aa)
NLRP7NLR family pyrin domain containing 7. (955 aa)
CASP8Caspase 8; Belongs to the peptidase C14A family. (479 aa)
MYD88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (317 aa)
CARD6Caspase recruitment domain family member 6. (1037 aa)
LOC105534152Uncharacterized protein; Belongs to the peptidase C14A family. (352 aa)
IRAK4Interleukin 1 receptor associated kinase 4. (460 aa)
MEFVMEFV innate immuity regulator, pyrin. (759 aa)
LRRD1Leucine rich repeats and death domain containing 1. (867 aa)
DTHD1Death domain containing 1. (910 aa)
ENSMLEP00000013258Uncharacterized protein. (107 aa)
NFKB1Nuclear factor kappa B subunit 1. (969 aa)
LOC105534146Uncharacterized protein; Belongs to the peptidase C14A family. (410 aa)
NLRP6NLR family pyrin domain containing 6. (1044 aa)
UNC5DUnc-5 netrin receptor D. (944 aa)
NLRC4NLR family CARD domain containing 4. (1024 aa)
DEDD2Death effector domain containing 2. (326 aa)
DDX58DExD/H-box helicase 58. (925 aa)
ANKDD1BAnkyrin repeat and death domain containing 1B. (528 aa)
CFLARCASP8 and FADD like apoptosis regulator; Belongs to the peptidase C14A family. (480 aa)
CASP5Caspase 5; Belongs to the peptidase C14A family. (446 aa)
CARD9Caspase recruitment domain family member 9. (992 aa)
NLRP1NLR family pyrin domain containing 1. (1480 aa)
PYDC1Pyrin domain containing 1. (92 aa)
CASP4Caspase 4; Belongs to the peptidase C14A family. (377 aa)
IGFLR1IGF like family receptor 1. (353 aa)
MNDAMyeloid cell nuclear differentiation antigen. (407 aa)
TNFRSF25TNF receptor superfamily member 25. (429 aa)
ANKDD1AAnkyrin repeat and death domain containing 1A. (513 aa)
DEDDDeath effector domain containing. (347 aa)
NLRP5NLR family pyrin domain containing 5. (1192 aa)
TNFRSF21TNF receptor superfamily member 21. (657 aa)
RIPK1Receptor interacting serine/threonine kinase 1. (620 aa)
NFKB2Nuclear factor kappa B subunit 2. (900 aa)
PYCARDPYD and CARD domain containing. (195 aa)
TNFRSF10ATNF receptor superfamily member 10a. (433 aa)
CARD18Caspase recruitment domain family member 18. (91 aa)
PYDC2Pyrin domain containing 2. (139 aa)
NGFRNerve growth factor receptor. (423 aa)
TNFRSF10BTNF receptor superfamily member 10b. (445 aa)
PEA15Proliferation and apoptosis adaptor protein 15. (151 aa)
IFIH1Interferon induced with helicase C domain 1. (1025 aa)
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
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