STRINGSTRING
NELFB NELFB POLR2E POLR2E ENSMLEP00000002991 ENSMLEP00000002991 NELFCD NELFCD CDK9 CDK9 RTF1 RTF1 SUPT4H1 SUPT4H1 GTF2F2 GTF2F2 MLLT3 MLLT3 ELL ELL CTR9 CTR9 EAF1 EAF1 GTF2F1 GTF2F1 ELOA2 ELOA2 LOC105553920 LOC105553920 AFF4 AFF4 TCEA1 TCEA1 IWS1 IWS1 LOC105537007 LOC105537007 NELFE NELFE SUPT6H SUPT6H NCBP1 NCBP1 POLR2A POLR2A NELFA NELFA CCNH CCNH ENSMLEP00000014641 ENSMLEP00000014641 ENSMLEP00000015363 ENSMLEP00000015363 POLR2C POLR2C POLR2G POLR2G GTF2H5 GTF2H5 POLR2F POLR2F POLR2J POLR2J LOC105548148 LOC105548148 CDK7 CDK7 MLLT1 MLLT1 CTDP1 CTDP1 MNAT1 MNAT1 CDC73 CDC73 WDR61 WDR61 POLR2D POLR2D SUPT5H SUPT5H GTF2H3 GTF2H3 POLR2K POLR2K POLR2B POLR2B AFF1 AFF1 EAF2 EAF2 POLR2I POLR2I POLR2H POLR2H NCBP2 NCBP2 ENSMLEP00000031878 ENSMLEP00000031878 ELOC ELOC SSRP1 SSRP1 ENSMLEP00000035771 ENSMLEP00000035771 ERCC3 ERCC3 GTF2H1 GTF2H1 PAF1 PAF1 CCNK CCNK GTF2H4 GTF2H4 ELOA ELOA LEO1 LEO1 ERCC2 ERCC2 SUPT16H SUPT16H CCNT1 CCNT1 CCNT2 CCNT2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NELFBNegative elongation factor complex member B. (607 aa)
POLR2ERNA polymerase II subunit E. (176 aa)
ENSMLEP00000002991Uncharacterized protein. (68 aa)
NELFCDNegative elongation factor complex member C/D. (617 aa)
CDK9Cyclin dependent kinase 9; Belongs to the protein kinase superfamily. (372 aa)
RTF1RTF1 homolog, Paf1/RNA polymerase II complex component. (575 aa)
SUPT4H1Transcription elongation factor SPT4; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II; Belongs to the SPT4 family. (117 aa)
GTF2F2General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (249 aa)
MLLT3MLLT3 super elongation complex subunit. (504 aa)
ELLElongation factor for RNA polymerase II. (488 aa)
CTR9CTR9 homolog, Paf1/RNA polymerase II complex component. (1173 aa)
EAF1ELL associated factor 1. (268 aa)
GTF2F1Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (545 aa)
ELOA2TFIIS N-terminal domain-containing protein. (546 aa)
LOC105553920BSD domain-containing protein. (430 aa)
AFF4AF4/FMR2 family member 4. (1122 aa)
TCEA1Transcription elongation factor A1. (301 aa)
IWS1Interacts with SUPT6H, CTD assembly factor 1. (817 aa)
LOC105537007Ubiquitin-like domain-containing protein. (103 aa)
NELFENegative elongation factor complex member E. (393 aa)
SUPT6HTranscription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family. (1708 aa)
NCBP1Nuclear cap binding protein subunit 1. (790 aa)
POLR2ADNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1936 aa)
NELFANegative elongation factor complex member A. (466 aa)
CCNHCyclin H; Belongs to the cyclin family. (325 aa)
ENSMLEP00000014641Spt4 domain-containing protein. (94 aa)
ENSMLEP00000015363Uncharacterized protein. (66 aa)
POLR2CRNA polymerase II subunit C. (275 aa)
POLR2GRNA polymerase II subunit G. (172 aa)
GTF2H5General transcription factor IIH subunit 5. (71 aa)
POLR2FRNA polymerase II subunit F. (158 aa)
POLR2JRNA_pol_L_2 domain-containing protein. (159 aa)
LOC105548148Protein kinase domain-containing protein. (312 aa)
CDK7Cyclin dependent kinase 7; Belongs to the protein kinase superfamily. (346 aa)
MLLT1MLLT1 super elongation complex subunit. (458 aa)
CTDP1RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (861 aa)
MNAT1MNAT1 component of CDK activating kinase. (234 aa)
CDC73Cell division cycle 73. (531 aa)
WDR61WD repeat domain 61. (305 aa)
POLR2DRNA polymerase II subunit D. (142 aa)
SUPT5HTranscription elongation factor SPT5. (1087 aa)
GTF2H3General transcription factor IIH subunit 3. (308 aa)
POLR2KRNA polymerase II subunit K. (58 aa)
POLR2BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1167 aa)
AFF1AF4/FMR2 family member 1. (1221 aa)
EAF2ELL associated factor 2. (263 aa)
POLR2IDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (125 aa)
POLR2HDNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (150 aa)
NCBP2Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (89 aa)
ENSMLEP00000031878Spt4 domain-containing protein. (99 aa)
ELOCElongin C; Belongs to the SKP1 family. (96 aa)
SSRP1FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (709 aa)
ENSMLEP00000035771Uncharacterized protein. (68 aa)
ERCC3ERCC excision repair 3, TFIIH core complex helicase subunit. (782 aa)
GTF2H1General transcription factor IIH subunit 1. (548 aa)
PAF1PAF1 homolog, Paf1/RNA polymerase II complex component. (531 aa)
CCNKCyclin K; Belongs to the cyclin family. (580 aa)
GTF2H4General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (462 aa)
ELOAElongin A. (749 aa)
LEO1LEO1 homolog, Paf1/RNA polymerase II complex component. (666 aa)
ERCC2ERCC excision repair 2, TFIIH core complex helicase subunit. (760 aa)
SUPT16HSPT16 homolog, facilitates chromatin remodeling subunit. (1003 aa)
CCNT1Cyclin T1; Belongs to the cyclin family. (728 aa)
CCNT2Cyclin T2; Belongs to the cyclin family. (730 aa)
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
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