STRINGSTRING
MLST8 MLST8 CYFIP1 CYFIP1 TENM1 TENM1 VEGFC VEGFC TGFB1I1 TGFB1I1 MAPKAP1 MAPKAP1 NCKAP1L NCKAP1L VEGFD VEGFD TENM2 TENM2 CTNNA1 CTNNA1 NRP1 NRP1 NCK2 NCK2 MAPK14 MAPK14 AHCYL1 AHCYL1 SH2D2A SH2D2A ROCK1 ROCK1 AKT3 AKT3 SHC2 SHC2 ACTG1 ACTG1 CTNND1 CTNND1 SHE SHE HRAS HRAS NCKAP1 NCKAP1 CDC42 CDC42 THEM4 THEM4 SRC SRC WASF2 WASF2 TRIB3 TRIB3 LOC105542528 LOC105542528 NCF2 NCF2 PRKCD PRKCD PIK3R1 PIK3R1 BCAR1 BCAR1 ABI2 ABI2 HSP90AA1 HSP90AA1 PRKACB PRKACB MAPK13 MAPK13 PAK3 PAK3 WASF3 WASF3 VEGFB VEGFB PRR5 PRR5 NRAS NRAS HSH2D HSH2D MAPKAPK3 MAPKAPK3 KDR KDR ACTB ACTB CSDE1 CSDE1 VEGFA VEGFA PLCG1 PLCG1 STX12 STX12 RHOA RHOA PIK3CB PIK3CB AKT1 AKT1 MAPK12 MAPK12 ENSMLEP00000027131 ENSMLEP00000027131 CASS4 CASS4 STX7 STX7 AXL AXL SPHK1 SPHK1 RICTOR RICTOR PRKCB PRKCB NCF1 NCF1 ABI1 ABI1 NEDD9 NEDD9 MAPK11 MAPK11 NRP2 NRP2 EFS EFS ITPR3 ITPR3 AKT2 AKT2 ELMO3 ELMO3 ELMO1 ELMO1 PRKCA PRKCA TENM4 TENM4 PRKACA PRKACA ARVCF ARVCF RASA1 RASA1 FLT1 FLT1 LOC105540399 LOC105540399 PIK3CA PIK3CA SHB SHB ELMO2 ELMO2 PAK1 PAK1 ENSMLEP00000018677 ENSMLEP00000018677 TENM3 TENM3 ENSMLEP00000018399 ENSMLEP00000018399 FNDC3A FNDC3A PRKCZ PRKCZ FNDC3B FNDC3B AAMP AAMP FYN FYN CYFIP2 CYFIP2 ITGB3 ITGB3 PTK2 PTK2 LOC105532771 LOC105532771 CYBA CYBA NOS3 NOS3 JUP JUP PTK2B PTK2B PDPK1 PDPK1 LOC105553882 LOC105553882 SHF SHF ENSMLEP00000011086 ENSMLEP00000011086 VAV1 VAV1 VAV2 VAV2 CAV1 CAV1 LPXN LPXN ROCK2 ROCK2 BRK1 BRK1 ITPR1 ITPR1 BAIAP2 BAIAP2 PGF PGF NCK1 NCK1 VAV3 VAV3 FLT4 FLT4 CTNNB1 CTNNB1 KRAS KRAS LOC105530991 LOC105530991 CDH5 CDH5 NCF4 NCF4 PAK2 PAK2 ERAS ERAS SZRD1 SZRD1 ACTL7A ACTL7A RNF222 RNF222 ITPR2 ITPR2 ACTRT1 ACTRT1 MAPKAPK2 MAPKAPK2 MTOR MTOR CRK CRK ITGAV ITGAV WASF1 WASF1 ACTRT2 ACTRT2 ACTL7B ACTL7B PXN PXN PIK3R2 PIK3R2 DOCK1 DOCK1 ENSMLEP00000001389 ENSMLEP00000001389 ACTL8 ACTL8 CYBB CYBB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MLST8MTOR associated protein, LST8 homolog. (335 aa)
CYFIP1Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1233 aa)
TENM1Teneurin transmembrane protein 1. (2342 aa)
VEGFCVascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (402 aa)
TGFB1I1Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways. (461 aa)
MAPKAP1MAPK associated protein 1. (522 aa)
NCKAP1LNCK associated protein 1 like. (1056 aa)
VEGFDVascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. (354 aa)
TENM2Teneurin transmembrane protein 2. (2774 aa)
CTNNA1Catenin alpha 1. (906 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (924 aa)
NCK2Cytoplasmic protein. (380 aa)
MAPK14Mitogen-activated protein kinase. (350 aa)
AHCYL1Adenosylhomocysteinase like 1; Belongs to the adenosylhomocysteinase family. (509 aa)
SH2D2ASH2 domain containing 2A. (399 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1368 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
SHC2Uncharacterized protein. (483 aa)
ACTG1Actin gamma 1. (376 aa)
CTNND1Catenin delta 1. (968 aa)
SHESrc homology 2 domain containing E. (398 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
NCKAP1NCK associated protein 1. (1115 aa)
CDC42Uncharacterized protein. (191 aa)
THEM4Thioesterase superfamily member 4. (240 aa)
SRCTyrosine-protein kinase. (542 aa)
WASF2WASP family member 2. (498 aa)
TRIB3Tribbles pseudokinase 3. (385 aa)
LOC105542528Uncharacterized protein. (173 aa)
NCF2Neutrophil cytosolic factor 2. (526 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
BCAR1BCAR1 scaffold protein, Cas family member. (916 aa)
ABI2Abl interactor 2. (485 aa)
HSP90AA1Heat shock protein 90 alpha family class A member 1. (823 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
MAPK13Mitogen-activated protein kinase. (397 aa)
PAK3P21 (RAC1) activated kinase 3. (580 aa)
WASF3WASP family member 3. (502 aa)
VEGFBVascular endothelial growth factor B; Belongs to the PDGF/VEGF growth factor family. (168 aa)
PRR5Proline rich 5. (384 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
HSH2DHematopoietic SH2 domain containing. (310 aa)
MAPKAPK3MAPK activated protein kinase 3; Belongs to the protein kinase superfamily. (382 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
ACTBActin beta. (375 aa)
CSDE1Cold shock domain containing E1. (844 aa)
VEGFAVascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (210 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1276 aa)
STX12Syntaxin 12; Belongs to the syntaxin family. (276 aa)
RHOARas homolog family member A. (193 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1073 aa)
AKT1Non-specific serine/threonine protein kinase. (432 aa)
MAPK12Mitogen-activated protein kinase. (292 aa)
ENSMLEP00000027131Uncharacterized protein. (130 aa)
CASS4Cas scaffold protein family member 4. (786 aa)
STX7Syntaxin 7; Belongs to the syntaxin family. (261 aa)
AXLAXL receptor tyrosine kinase. (874 aa)
SPHK1Sphingosine kinase 1. (470 aa)
RICTORRPTOR independent companion of MTOR complex 2. (1699 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (582 aa)
NCF1Neutrophil cytosolic factor 1. (390 aa)
ABI1Abl interactor 1. (469 aa)
NEDD9Neural precursor cell expressed, developmentally down-regulated 9. (820 aa)
MAPK11Mitogen-activated protein kinase. (224 aa)
NRP2Neuropilin; Belongs to the neuropilin family. (930 aa)
EFSEmbryonal Fyn-associated substrate. (561 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2675 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
ELMO3Engulfment and cell motility 3. (738 aa)
ELMO1Engulfment and cell motility 1. (727 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (614 aa)
TENM4Teneurin transmembrane protein 4. (2769 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (352 aa)
ARVCFARVCF delta catenin family member. (962 aa)
RASA1RAS p21 protein activator 1. (1051 aa)
FLT1Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1316 aa)
LOC105540399Uncharacterized protein; Belongs to the actin family. (362 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
SHBSH2 domain containing adaptor protein B. (297 aa)
ELMO2Engulfment and cell motility 2. (726 aa)
PAK1Non-specific serine/threonine protein kinase. (545 aa)
ENSMLEP00000018677Uncharacterized protein. (185 aa)
TENM3Teneurin transmembrane protein 3. (2699 aa)
ENSMLEP00000018399Uncharacterized protein. (153 aa)
FNDC3AFibronectin type III domain containing 3A. (1198 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (596 aa)
FNDC3BFibronectin type III domain containing 3B. (1206 aa)
AAMPAngio associated migratory cell protein. (453 aa)
FYNTyrosine-protein kinase. (537 aa)
CYFIP2Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1278 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (788 aa)
PTK2Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1096 aa)
LOC105532771Uncharacterized protein. (665 aa)
CYBACytochrome b-245 alpha chain. (194 aa)
NOS3Nitric oxide synthase; Produces nitric oxide (NO). (1155 aa)
JUPJunction plakoglobin. (745 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
PDPK13-phosphoinositide dependent protein kinase 1. (529 aa)
LOC105553882Uncharacterized protein. (356 aa)
SHFSrc homology 2 domain containing F. (424 aa)
ENSMLEP00000011086Ig-like domain-containing protein. (174 aa)
VAV1Vav guanine nucleotide exchange factor 1. (766 aa)
VAV2Vav guanine nucleotide exchange factor 2. (787 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (147 aa)
LPXNLeupaxin; Transcriptional coactivator for androgen receptor (AR) and serum response factor (SRF). Contributes to the regulation of cell adhesion, spreading and cell migration and acts as a negative regulator in integrin-mediated cell adhesion events. Suppresses the integrin- induced tyrosine phosphorylation of paxillin (PXN). (400 aa)
ROCK2Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1375 aa)
BRK1BRICK1 subunit of SCAR/WAVE actin nucleating complex. (75 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2731 aa)
BAIAP2BAI1 associated protein 2. (490 aa)
PGFPlacental growth factor; Belongs to the PDGF/VEGF growth factor family. (170 aa)
NCK1Cytoplasmic protein. (377 aa)
VAV3Vav guanine nucleotide exchange factor 3. (875 aa)
FLT4Fms related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1169 aa)
CTNNB1Catenin beta 1. (781 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
LOC105530991Uncharacterized protein. (185 aa)
CDH5Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. (705 aa)
NCF4Neutrophil cytosolic factor 4. (366 aa)
PAK2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (477 aa)
ERASES cell expressed Ras. (233 aa)
SZRD1SUZ RNA binding domain containing 1. (152 aa)
ACTL7AActin like 7A; Belongs to the actin family. (435 aa)
RNF222Ring finger protein 222. (220 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2663 aa)
ACTRT1Actin related protein T1; Belongs to the actin family. (375 aa)
MAPKAPK2MAPK activated protein kinase 2. (362 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa)
CRKCRK proto-oncogene, adaptor protein. (245 aa)
ITGAVIntegrin subunit alpha V; Belongs to the integrin alpha chain family. (1048 aa)
WASF1WASP family member 1. (559 aa)
ACTRT2Actin related protein T2; Belongs to the actin family. (377 aa)
ACTL7BActin like 7B; Belongs to the actin family. (415 aa)
PXNPaxillin. (1079 aa)
PIK3R2Uncharacterized protein. (587 aa)
DOCK1Dedicator of cytokinesis 1; Belongs to the DOCK family. (1824 aa)
ENSMLEP00000001389Uncharacterized protein. (61 aa)
ACTL8Actin like 8; Belongs to the actin family. (366 aa)
CYBBCytochrome b-245 beta chain. (486 aa)
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
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