STRINGSTRING
ZAP70 ZAP70 PGBD4 PGBD4 RPS27A RPS27A ENSMLEP00000000931 ENSMLEP00000000931 PIK3R2 PIK3R2 UBE2NL UBE2NL PSMD13 PSMD13 PSMB9 PSMB9 TRAF6 TRAF6 HLA-DRA HLA-DRA LOC105537709 LOC105537709 PSME3 PSME3 PSMB11 PSMB11 LOC105537163 LOC105537163 CD3G CD3G PSMA4 PSMA4 PSMB4 PSMB4 LOC105541098 LOC105541098 PSMB6 PSMB6 LOC105537710 LOC105537710 ENSMLEP00000005424 ENSMLEP00000005424 PSMC5 PSMC5 ENSMLEP00000005586 ENSMLEP00000005586 PSMB3 PSMB3 ENSMLEP00000006240 ENSMLEP00000006240 ENSMLEP00000006413 ENSMLEP00000006413 PAK2 PAK2 LOC105540228 LOC105540228 EVL EVL LOC105540679 LOC105540679 SKP1 SKP1 LOC105536598 LOC105536598 ENSMLEP00000008311 ENSMLEP00000008311 PSMB1 PSMB1 PSMB8 PSMB8 NCK1 NCK1 PSMD9 PSMD9 LOC105540229 LOC105540229 ENSMLEP00000011388 ENSMLEP00000011388 PDPK1 PDPK1 PSMD5 PSMD5 NFKB1 NFKB1 PSMA1 PSMA1 PSMA2 PSMA2 CD3D CD3D PTPRC PTPRC LCK LCK PRKCQ PRKCQ PTPRJ PTPRJ PSMD10 PSMD10 ENSMLEP00000016378 ENSMLEP00000016378 ENSMLEP00000016528 ENSMLEP00000016528 PAG1 PAG1 ENSMLEP00000016698 ENSMLEP00000016698 WAS WAS PSMD4 PSMD4 CD4 CD4 IKBKB IKBKB PSMC3 PSMC3 ENSMLEP00000018394 ENSMLEP00000018394 PSMA5 PSMA5 PAK1 PAK1 PSMA7 PSMA7 PSMF1 PSMF1 LOC105537711 LOC105537711 LOC105545975 LOC105545975 PIK3CA PIK3CA ENSMLEP00000019789 ENSMLEP00000019789 PSMD11 PSMD11 PSMB7 PSMB7 LOC105537712 LOC105537712 SPNS3 SPNS3 PSMD12 PSMD12 CSK CSK LOC105536463 LOC105536463 FBXW11 FBXW11 SPNS1 SPNS1 MAP3K20 MAP3K20 PSMD1 PSMD1 PSMD2 PSMD2 PTPN22 PTPN22 CHUK CHUK UBE2D1 UBE2D1 LOC105531108 LOC105531108 BCL10 BCL10 ENSMLEP00000024034 ENSMLEP00000024034 PLCG2 PLCG2 RIPK2 RIPK2 ENSMLEP00000024603 ENSMLEP00000024603 PSMD8 PSMD8 LCP2 LCP2 ENSMLEP00000025123 ENSMLEP00000025123 FYB1 FYB1 PTEN PTEN PSME4 PSME4 BTRC BTRC NFKBIA NFKBIA PSME1 PSME1 INPP5D INPP5D PSMC1 PSMC1 PSMC4 PSMC4 GRAP2 GRAP2 PIK3CB PIK3CB TRAV29DV5 TRAV29DV5 PSMA6 PSMA6 PLCG1 PLCG1 UBA52 UBA52 CD101 CD101 ENAH ENAH MAP3K7 MAP3K7 TAB2 TAB2 PSMC6 PSMC6 PSMD3 PSMD3 TRAC TRAC PSMB10 PSMB10 CDC34 CDC34 PAK3 PAK3 PSMC2 PSMC2 LOC105536146 LOC105536146 PIK3R1 PIK3R1 PSMB2 PSMB2 ENSMLEP00000034242 ENSMLEP00000034242 PSME2 PSME2 VASP VASP ITK ITK LAT LAT RELA RELA PSMA3 PSMA3 TRAT1 TRAT1 LOC105540670 LOC105540670 PSMA8 PSMA8 CD3E CD3E MALT1 MALT1 PSMB5 PSMB5 PSMD7 PSMD7 ENSMLEP00000038111 ENSMLEP00000038111 ENSMLEP00000038532 ENSMLEP00000038532 ENSMLEP00000038668 ENSMLEP00000038668 PSMD14 PSMD14 CARD11 CARD11 PSMD6 PSMD6 CD247 CD247 CUL1 CUL1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ZAP70Tyrosine-protein kinase. (507 aa)
PGBD4PiggyBac transposable element derived 4. (585 aa)
RPS27AUbiquitin-like domain-containing protein. (138 aa)
ENSMLEP00000000931MPN domain-containing protein. (299 aa)
PIK3R2Uncharacterized protein. (587 aa)
UBE2NLUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (89 aa)
PSMD13Proteasome 26S subunit, non-ATPase 13. (351 aa)
PSMB9Proteasome subunit beta. (196 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (522 aa)
HLA-DRAMajor histocompatibility complex, class II, DR alpha; Belongs to the MHC class II family. (254 aa)
LOC105537709Ig-like domain-containing protein; Belongs to the MHC class II family. (256 aa)
PSME3Proteasome activator subunit 3. (267 aa)
PSMB11Proteasome subunit beta. (300 aa)
LOC105537163Ig-like domain-containing protein. (264 aa)
CD3GCD3g molecule. (166 aa)
PSMA4Proteasome subunit alpha type. (261 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (274 aa)
LOC105541098Ubiquitin-like domain-containing protein. (156 aa)
PSMB6Proteasome subunit beta. (242 aa)
LOC105537710Ig-like domain-containing protein. (228 aa)
ENSMLEP00000005424UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (142 aa)
PSMC5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa)
ENSMLEP00000005586ATPase_AAA_core domain-containing protein; Belongs to the AAA ATPase family. (179 aa)
PSMB3Proteasome subunit beta. (205 aa)
ENSMLEP00000006240Ubiquitin-like domain-containing protein. (127 aa)
ENSMLEP00000006413AAA domain-containing protein; Belongs to the AAA ATPase family. (423 aa)
PAK2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (477 aa)
LOC105540228Ig-like domain-containing protein. (258 aa)
EVLEnah/Vasp-like; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. Belongs to the Ena/VASP family. (418 aa)
LOC105540679UBIQUITIN_CONJUGAT_2 domain-containing protein. (147 aa)
SKP1S-phase kinase associated protein 1; Belongs to the SKP1 family. (165 aa)
LOC105536598Ubiquitin-like domain-containing protein. (156 aa)
ENSMLEP00000008311Uncharacterized protein; Belongs to the SKP1 family. (142 aa)
PSMB1Proteasome subunit beta. (241 aa)
PSMB8Proteasome subunit beta. (276 aa)
NCK1Cytoplasmic protein. (377 aa)
PSMD9PDZ domain-containing protein. (223 aa)
LOC105540229Ig-like domain-containing protein; Belongs to the MHC class II family. (269 aa)
ENSMLEP00000011388Ubiquitin-like domain-containing protein. (120 aa)
PDPK13-phosphoinositide dependent protein kinase 1. (529 aa)
PSMD5Proteasome 26S subunit, non-ATPase 5. (508 aa)
NFKB1Nuclear factor kappa B subunit 1. (969 aa)
PSMA1Proteasome subunit alpha type. (269 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
CD3DCD3d molecule. (171 aa)
PTPRCProtein tyrosine phosphatase receptor type C. (1241 aa)
LCKTyrosine-protein kinase. (536 aa)
PRKCQProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (706 aa)
PTPRJProtein tyrosine phosphatase receptor type J. (1306 aa)
PSMD10Proteasome 26S subunit, non-ATPase 10. (226 aa)
ENSMLEP00000016378AAA domain-containing protein. (201 aa)
ENSMLEP00000016528Uncharacterized protein. (191 aa)
PAG1Phosphoprotein membrane anchor with glycosphingolipid microdomains 1. (432 aa)
ENSMLEP00000016698AAA domain-containing protein; Belongs to the AAA ATPase family. (390 aa)
WASWASP actin nucleation promoting factor. (503 aa)
PSMD4Proteasome 26S subunit, non-ATPase 4. (378 aa)
CD4CD4 molecule. (458 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (706 aa)
PSMC3AAA domain-containing protein; Belongs to the AAA ATPase family. (446 aa)
ENSMLEP00000018394UBIQUITIN_CONJUGAT_2 domain-containing protein. (129 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
PAK1Non-specific serine/threonine protein kinase. (545 aa)
PSMA7Proteasome endopeptidase complex. (178 aa)
PSMF1Proteasome inhibitor subunit 1. (271 aa)
LOC105537711Ig-like domain-containing protein. (266 aa)
LOC105545975Uncharacterized protein. (448 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
ENSMLEP00000019789ANK_REP_REGION domain-containing protein. (165 aa)
PSMD11Proteasome 26S subunit, non-ATPase 11. (357 aa)
PSMB7Proteasome subunit beta. (302 aa)
LOC105537712Ig-like domain-containing protein. (239 aa)
SPNS3Sphingolipid transporter 3 (putative). (512 aa)
PSMD12Proteasome 26S subunit, non-ATPase 12. (456 aa)
CSKTyrosine-protein kinase. (450 aa)
LOC105536463AAA domain-containing protein; Belongs to the AAA ATPase family. (366 aa)
FBXW11F-box and WD repeat domain containing 11. (546 aa)
SPNS1Sphingolipid transporter 1 (putative). (476 aa)
MAP3K20Mitogen-activated protein kinase kinase kinase 20. (800 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (888 aa)
PTPN22Protein tyrosine phosphatase non-receptor type 22. (813 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (745 aa)
UBE2D1Ubiquitin conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family. (148 aa)
LOC105531108Ig-like domain-containing protein; Belongs to the MHC class II family. (269 aa)
BCL10BCL10 immune signaling adaptor. (312 aa)
ENSMLEP00000024034UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (142 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1221 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (540 aa)
ENSMLEP00000024603UBIQUITIN_CONJUGAT_2 domain-containing protein. (102 aa)
PSMD8Proteasome 26S subunit, non-ATPase 8. (350 aa)
LCP2Lymphocyte cytosolic protein 2. (533 aa)
ENSMLEP00000025123CSN8_PSD8_EIF3K domain-containing protein. (254 aa)
FYB1FYN binding protein 1. (839 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
PSME4Proteasome activator subunit 4. (1795 aa)
BTRCBeta-transducin repeat containing E3 ubiquitin protein ligase. (605 aa)
NFKBIAANK_REP_REGION domain-containing protein. (305 aa)
PSME1Proteasome activator subunit 1. (284 aa)
INPP5DInositol polyphosphate-5-phosphatase D. (1180 aa)
PSMC1Proteasome 26S subunit, ATPase 1; Belongs to the AAA ATPase family. (440 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa)
GRAP2GRB2 related adaptor protein 2. (330 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1073 aa)
TRAV29DV5T cell receptor alpha variable 29/delta variable 5 (gene/pseudogene). (156 aa)
PSMA6Proteasome subunit alpha type. (252 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1276 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
CD101CD101 molecule. (1021 aa)
ENAHENAH actin regulator. (790 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
TAB2TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (693 aa)
PSMC6AAA domain-containing protein; Belongs to the AAA ATPase family. (403 aa)
PSMD3Proteasome 26S subunit, non-ATPase 3. (534 aa)
TRACT cell receptor alpha constant. (110 aa)
PSMB10Proteasome subunit beta. (273 aa)
CDC34Cell division cycle 34; Belongs to the ubiquitin-conjugating enzyme family. (226 aa)
PAK3P21 (RAC1) activated kinase 3. (580 aa)
PSMC2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (467 aa)
LOC105536146Ig-like domain-containing protein. (327 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
PSMB2Proteasome subunit beta. (201 aa)
ENSMLEP00000034242Uncharacterized protein. (173 aa)
PSME2Proteasome activator subunit 2. (239 aa)
VASPVasodilator stimulated phosphoprotein. (432 aa)
ITKTyrosine-protein kinase. (620 aa)
LATLinker for activation of T cells. (235 aa)
RELARELA proto-oncogene, NF-kB subunit. (550 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
TRAT1T cell receptor associated transmembrane adaptor 1. (187 aa)
LOC105540670Ig-like domain-containing protein. (261 aa)
PSMA8Proteasome subunit alpha type. (250 aa)
CD3ECD3e molecule. (198 aa)
MALT1MALT1 paracaspase. (778 aa)
PSMB5Proteasome subunit beta. (263 aa)
PSMD7Proteasome 26S subunit, non-ATPase 7. (324 aa)
ENSMLEP00000038111Proteasome endopeptidase complex. (222 aa)
ENSMLEP00000038532Uncharacterized protein. (260 aa)
ENSMLEP00000038668Prot_ATP_ID_OB domain-containing protein. (166 aa)
PSMD14Proteasome 26S subunit, non-ATPase 14. (315 aa)
CARD11Caspase recruitment domain family member 11. (1154 aa)
PSMD6Proteasome 26S subunit, non-ATPase 6. (442 aa)
CD247CD247 molecule. (164 aa)
CUL1Cullin 1; Belongs to the cullin family. (776 aa)
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
Server load: low (24%) [HD]