29 items (Mandrillus leucophaeus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RPS27A	Ubiquitin-like domain-containing protein. (138 aa)
	TGFB1	Transforming growth factor beta 1. (226 aa)
	SMURF2	SMAD specific E3 ubiquitin protein ligase 2. (624 aa)
	LOC105541098	Ubiquitin-like domain-containing protein. (156 aa)
	ENSMLEP00000006240	Ubiquitin-like domain-containing protein. (127 aa)
	LOC105536598	Ubiquitin-like domain-containing protein. (156 aa)
	PPP1CA	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (355 aa)
	ENSMLEP00000011388	Ubiquitin-like domain-containing protein. (120 aa)
	BAMBI	BMP and activin membrane bound inhibitor. (345 aa)
	ZFYVE9	Zinc finger FYVE domain-containing protein. (1425 aa)
	PPP1CB	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (322 aa)
	LDLRAD4	Low density lipoprotein receptor class A domain containing 4. (306 aa)
	MTMR4	Myotubularin related protein 4. (1199 aa)
	XPO1	Exportin 1. (1070 aa)
	SMAD3	Mothers against decapentaplegic homolog. (425 aa)
	TGFBR1	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (502 aa)
	USP15	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (981 aa)
	STUB1	STIP1 homology and U-box containing protein 1. (250 aa)
	PMEPA1	Prostate transmembrane protein, androgen induced 1. (259 aa)
	SMAD2	Mothers against decapentaplegic homolog. (457 aa)
	PPP1CC	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (355 aa)
	UBA52	Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
	SMAD7	MH2 domain-containing protein. (211 aa)
	ENSMLEP00000034242	Uncharacterized protein. (173 aa)
	SMURF1	E3 ubiquitin-protein ligase. (748 aa)
	TGFBR2	TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (560 aa)
	STRAP	Serine/threonine kinase receptor associated protein. (363 aa)
	NEDD4L	NEDD4 like E3 ubiquitin protein ligase. (1257 aa)
	PPP1R15A	Protein phosphatase 1 regulatory subunit 15A. (672 aa)

Your Current Organism:

Mandrillus leucophaeus

NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BAMBI	SMAD2	ENSMLEP00000012217	ENSMLEP00000027206	BMP and activin membrane bound inhibitor.	Mothers against decapentaplegic homolog.	0.516
BAMBI	SMAD3	ENSMLEP00000012217	ENSMLEP00000016851	BMP and activin membrane bound inhibitor.	Mothers against decapentaplegic homolog.	0.512
BAMBI	SMAD7	ENSMLEP00000012217	ENSMLEP00000029308	BMP and activin membrane bound inhibitor.	MH2 domain-containing protein.	0.919
BAMBI	TGFB1	ENSMLEP00000012217	ENSMLEP00000002550	BMP and activin membrane bound inhibitor.	Transforming growth factor beta 1.	0.686
BAMBI	TGFBR1	ENSMLEP00000012217	ENSMLEP00000021611	BMP and activin membrane bound inhibitor.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.942
BAMBI	TGFBR2	ENSMLEP00000012217	ENSMLEP00000036460	BMP and activin membrane bound inhibitor.	TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...]	0.717
ENSMLEP00000006240	ENSMLEP00000034242	ENSMLEP00000006240	ENSMLEP00000034242	Ubiquitin-like domain-containing protein.	Uncharacterized protein.	0.952
ENSMLEP00000006240	LOC105536598	ENSMLEP00000006240	ENSMLEP00000008278	Ubiquitin-like domain-containing protein.	Ubiquitin-like domain-containing protein.	0.980
ENSMLEP00000006240	LOC105541098	ENSMLEP00000006240	ENSMLEP00000004673	Ubiquitin-like domain-containing protein.	Ubiquitin-like domain-containing protein.	0.980
ENSMLEP00000006240	NEDD4L	ENSMLEP00000006240	ENSMLEP00000037227	Ubiquitin-like domain-containing protein.	NEDD4 like E3 ubiquitin protein ligase.	0.768
ENSMLEP00000006240	RPS27A	ENSMLEP00000006240	ENSMLEP00000000914	Ubiquitin-like domain-containing protein.	Ubiquitin-like domain-containing protein.	0.980
ENSMLEP00000006240	SMURF1	ENSMLEP00000006240	ENSMLEP00000034436	Ubiquitin-like domain-containing protein.	E3 ubiquitin-protein ligase.	0.749
ENSMLEP00000006240	SMURF2	ENSMLEP00000006240	ENSMLEP00000003476	Ubiquitin-like domain-containing protein.	SMAD specific E3 ubiquitin protein ligase 2.	0.833
ENSMLEP00000006240	STUB1	ENSMLEP00000006240	ENSMLEP00000026385	Ubiquitin-like domain-containing protein.	STIP1 homology and U-box containing protein 1.	0.557
ENSMLEP00000006240	UBA52	ENSMLEP00000006240	ENSMLEP00000029249	Ubiquitin-like domain-containing protein.	Ubiquitin A-52 residue ribosomal protein fusion product 1.	0.876
ENSMLEP00000006240	USP15	ENSMLEP00000006240	ENSMLEP00000023243	Ubiquitin-like domain-containing protein.	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family.	0.579
ENSMLEP00000011388	ENSMLEP00000034242	ENSMLEP00000011388	ENSMLEP00000034242	Ubiquitin-like domain-containing protein.	Uncharacterized protein.	0.952
ENSMLEP00000011388	LOC105536598	ENSMLEP00000011388	ENSMLEP00000008278	Ubiquitin-like domain-containing protein.	Ubiquitin-like domain-containing protein.	0.953
ENSMLEP00000011388	LOC105541098	ENSMLEP00000011388	ENSMLEP00000004673	Ubiquitin-like domain-containing protein.	Ubiquitin-like domain-containing protein.	0.953
ENSMLEP00000011388	NEDD4L	ENSMLEP00000011388	ENSMLEP00000037227	Ubiquitin-like domain-containing protein.	NEDD4 like E3 ubiquitin protein ligase.	0.768