STRINGSTRING
PDCD1 PDCD1 PGBD4 PGBD4 LYN LYN PIK3R2 PIK3R2 PPP2R5E PPP2R5E ICOS ICOS HLA-DRA HLA-DRA LOC105537709 LOC105537709 LOC105537163 LOC105537163 CD3G CD3G PDCD1LG2 PDCD1LG2 LOC105537710 LOC105537710 PPP2R5C PPP2R5C MTOR MTOR PTPN11 PTPN11 LOC105551588 LOC105551588 PAK2 PAK2 LOC105540228 LOC105540228 PPP2R5A PPP2R5A LOC105530991 LOC105530991 PPP4R4 PPP4R4 VAV1 VAV1 LOC105540229 LOC105540229 PPP2R1A PPP2R1A PDPK1 PDPK1 ENSMLEP00000012128 ENSMLEP00000012128 BTLA BTLA PPP4R1 PPP4R1 CD80 CD80 CD3D CD3D CD274 CD274 PPP2CA PPP2CA PTPN6 PTPN6 LCK LCK FYN FYN FNDC3B FNDC3B FNDC3A FNDC3A MAP3K14 MAP3K14 CD4 CD4 ENSMLEP00000017623 ENSMLEP00000017623 GRB2 GRB2 YES1 YES1 ENSMLEP00000018038 ENSMLEP00000018038 ENSMLEP00000018399 ENSMLEP00000018399 ENSMLEP00000018677 ENSMLEP00000018677 PAK1 PAK1 CD276 CD276 LOC105537711 LOC105537711 PIK3CA PIK3CA LOC105537712 LOC105537712 CSK CSK PPP2CB PPP2CB AKT2 AKT2 PPP2R5D PPP2R5D RELCH RELCH LOC105531108 LOC105531108 RICTOR RICTOR CD28 CD28 CTLA4 CTLA4 GRAP2 GRAP2 AKT1 AKT1 ENSMLEP00000028290 ENSMLEP00000028290 TRAV29DV5 TRAV29DV5 LOC105538326 LOC105538326 MLST8 MLST8 PRR5 PRR5 PIK3R3 PIK3R3 TRAC TRAC CD86 CD86 PAK3 PAK3 LOC105536146 LOC105536146 PIK3R1 PIK3R1 LOC105542528 LOC105542528 PPP2R5B PPP2R5B TRIB3 TRIB3 FNBP4 FNBP4 ENSMLEP00000035415 ENSMLEP00000035415 SRC SRC THEM4 THEM4 CDC42 CDC42 LOC105540670 LOC105540670 CD3E CD3E AKT3 AKT3 TNFRSF14 TNFRSF14 MAP3K8 MAP3K8 ENSMLEP00000038532 ENSMLEP00000038532 PPP2R1B PPP2R1B ICOSLG ICOSLG MAPKAP1 MAPKAP1 CD247 CD247
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PDCD1Programmed cell death 1. (288 aa)
PGBD4PiggyBac transposable element derived 4. (585 aa)
LYNTyrosine-protein kinase. (470 aa)
PIK3R2Uncharacterized protein. (587 aa)
PPP2R5ESerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (468 aa)
ICOSInducible T cell costimulator. (199 aa)
HLA-DRAMajor histocompatibility complex, class II, DR alpha; Belongs to the MHC class II family. (254 aa)
LOC105537709Ig-like domain-containing protein; Belongs to the MHC class II family. (256 aa)
LOC105537163Ig-like domain-containing protein. (264 aa)
CD3GCD3g molecule. (166 aa)
PDCD1LG2Programmed cell death 1 ligand 2. (273 aa)
LOC105537710Ig-like domain-containing protein. (228 aa)
PPP2R5CSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (580 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (656 aa)
LOC105551588Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (455 aa)
PAK2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (477 aa)
LOC105540228Ig-like domain-containing protein. (258 aa)
PPP2R5ASerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (525 aa)
LOC105530991Uncharacterized protein. (185 aa)
PPP4R4Protein phosphatase 4 regulatory subunit 4. (843 aa)
VAV1Vav guanine nucleotide exchange factor 1. (766 aa)
LOC105540229Ig-like domain-containing protein; Belongs to the MHC class II family. (269 aa)
PPP2R1AProtein phosphatase 2 scaffold subunit Aalpha. (589 aa)
PDPK13-phosphoinositide dependent protein kinase 1. (529 aa)
ENSMLEP00000012128Uncharacterized protein. (234 aa)
BTLAB and T lymphocyte associated. (289 aa)
PPP4R1Protein phosphatase 4 regulatory subunit 1. (919 aa)
CD80CD80 molecule. (288 aa)
CD3DCD3d molecule. (171 aa)
CD274CD274 molecule. (290 aa)
PPP2CASerine/threonine-protein phosphatase. (275 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (623 aa)
LCKTyrosine-protein kinase. (536 aa)
FYNTyrosine-protein kinase. (537 aa)
FNDC3BFibronectin type III domain containing 3B. (1206 aa)
FNDC3AFibronectin type III domain containing 3A. (1198 aa)
MAP3K14Mitogen-activated protein kinase kinase kinase 14. (947 aa)
CD4CD4 molecule. (458 aa)
ENSMLEP00000017623Tyrosine-protein kinase. (397 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
YES1Tyrosine-protein kinase. (543 aa)
ENSMLEP00000018038Uncharacterized protein. (427 aa)
ENSMLEP00000018399Uncharacterized protein. (153 aa)
ENSMLEP00000018677Uncharacterized protein. (185 aa)
PAK1Non-specific serine/threonine protein kinase. (545 aa)
CD276CD276 molecule. (534 aa)
LOC105537711Ig-like domain-containing protein. (266 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
LOC105537712Ig-like domain-containing protein. (239 aa)
CSKTyrosine-protein kinase. (450 aa)
PPP2CBSerine/threonine-protein phosphatase. (275 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
PPP2R5DSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (605 aa)
RELCHRAB11 binding and LisH domain, coiled-coil and HEAT repeat containing. (1195 aa)
LOC105531108Ig-like domain-containing protein; Belongs to the MHC class II family. (269 aa)
RICTORRPTOR independent companion of MTOR complex 2. (1699 aa)
CD28CD28 molecule. (220 aa)
CTLA4Cytotoxic T-lymphocyte associated protein 4. (223 aa)
GRAP2GRB2 related adaptor protein 2. (330 aa)
AKT1Non-specific serine/threonine protein kinase. (432 aa)
ENSMLEP00000028290Uncharacterized protein. (441 aa)
TRAV29DV5T cell receptor alpha variable 29/delta variable 5 (gene/pseudogene). (156 aa)
LOC105538326WRNPLPNID domain-containing protein. (953 aa)
MLST8MTOR associated protein, LST8 homolog. (335 aa)
PRR5Proline rich 5. (384 aa)
PIK3R3Phosphoinositide-3-kinase regulatory subunit 3. (461 aa)
TRACT cell receptor alpha constant. (110 aa)
CD86CD86 molecule. (329 aa)
PAK3P21 (RAC1) activated kinase 3. (580 aa)
LOC105536146Ig-like domain-containing protein. (327 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
LOC105542528Uncharacterized protein. (173 aa)
PPP2R5BSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (502 aa)
TRIB3Tribbles pseudokinase 3. (385 aa)
FNBP4Formin binding protein 4. (1017 aa)
ENSMLEP00000035415Uncharacterized protein. (519 aa)
SRCTyrosine-protein kinase. (542 aa)
THEM4Thioesterase superfamily member 4. (240 aa)
CDC42Uncharacterized protein. (191 aa)
LOC105540670Ig-like domain-containing protein. (261 aa)
CD3ECD3e molecule. (198 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
TNFRSF14TNF receptor superfamily member 14. (282 aa)
MAP3K8Mitogen-activated protein kinase kinase kinase 8. (467 aa)
ENSMLEP00000038532Uncharacterized protein. (260 aa)
PPP2R1BProtein phosphatase 2 scaffold subunit Abeta. (637 aa)
ICOSLGUncharacterized protein. (297 aa)
MAPKAP1MAPK associated protein 1. (522 aa)
CD247CD247 molecule. (164 aa)
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
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