STRINGSTRING
GNA14 GNA14 CCNE2 CCNE2 FKBP9 FKBP9 ENSMLEP00000012920 ENSMLEP00000012920 RGS9 RGS9 SKIV2L SKIV2L STAT3 STAT3 SPHK1 SPHK1 PDCL PDCL TUBA4A TUBA4A ARFGEF2 ARFGEF2 GNAQ GNAQ LOC105550079 LOC105550079 GNG2 GNG2 USP11 USP11 DCAF7 DCAF7 ENSMLEP00000007417 ENSMLEP00000007417 TBCC TBCC CSNK2A2 CSNK2A2 ENSMLEP00000006361 ENSMLEP00000006361 LOC105544901 LOC105544901 GNB3 GNB3 ERMARD ERMARD VBP1 VBP1 CCT7 CCT7 TBCA TBCA NOP56 NOP56 WRAP53 WRAP53 RGS11 RGS11 GNB4 GNB4 TCP1 TCP1 TUBB4B TUBB4B ENSMLEP00000001951 ENSMLEP00000001951 GNA11 GNA11 FBXW5 FBXW5 CCT3 CCT3 GNGT2 GNGT2 FBXW9 FBXW9 CCT6B CCT6B TUBAL3 TUBAL3 TUBB1 TUBB1 RGS7 RGS7 CCT4 CCT4 CSNK2A1 CSNK2A1 TUBB2B TUBB2B FBXL3 FBXL3 ENSMLEP00000027682 ENSMLEP00000027682 HDAC3 HDAC3 PDC PDC ENSMLEP00000028401 ENSMLEP00000028401 PFDN2 PFDN2 GNG12 GNG12 ACTB ACTB GNG5 GNG5 GNG3 GNG3 LOC105549611 LOC105549611 CCNE1 CCNE1 GNG4 GNG4 KIF13A KIF13A FBXW4 FBXW4 LOC105551879 LOC105551879 ARL2 ARL2 ENSMLEP00000040266 ENSMLEP00000040266 GAPDHS GAPDHS FBXW2 FBXW2 ENSMLEP00000039395 ENSMLEP00000039395 TUBA1C TUBA1C ARFGEF1 ARFGEF1 ENSMLEP00000038971 ENSMLEP00000038971 TUBA8 TUBA8 FKBP10 FKBP10 FBXO6 FBXO6 LOC105532182 LOC105532182 GNG13 GNG13 GBA GBA TP53 TP53 PFDN1 PFDN1 PFDN4 PFDN4 CSNK2B CSNK2B FBXO44 FBXO44 GNG8 GNG8 XRN2 XRN2 CCT5 CCT5 GNGT1 GNGT1 ENSMLEP00000024944 ENSMLEP00000024944 ENSMLEP00000024580 ENSMLEP00000024580 TBCD TBCD TUBB6 TUBB6 CCT8 CCT8 GNB2 GNB2 AP3M2 AP3M2 FBXL5 FBXL5 LOC105551099 LOC105551099 LOC105543661 LOC105543661 CCT6A CCT6A FBXW7 FBXW7 GNB5 GNB5 PFDN5 PFDN5 LONP2 LONP2 FBXO4 FBXO4 ENSMLEP00000020419 ENSMLEP00000020419 TBCB TBCB GNB1 GNB1 TUBB2A TUBB2A GNA15 GNA15 CCT2 CCT2 PFDN6 PFDN6 KIFC3 KIFC3 RGS6 RGS6 FBXW10 FBXW10 ENSMLEP00000015708 ENSMLEP00000015708 AP3M1 AP3M1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GNA14G protein subunit alpha 14. (355 aa)
CCNE2Cyclin E2; Belongs to the cyclin family. (404 aa)
FKBP9Peptidylprolyl isomerase. (593 aa)
ENSMLEP00000012920Uncharacterized protein. (361 aa)
RGS9Regulator of G protein signaling 9. (617 aa)
SKIV2LSki2 like RNA helicase. (1246 aa)
STAT3Signal transducer and activator of transcription. (693 aa)
SPHK1Sphingosine kinase 1. (470 aa)
PDCLPhosducin like. (301 aa)
TUBA4ATubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (448 aa)
ARFGEF2ADP ribosylation factor guanine nucleotide exchange factor 2. (1713 aa)
GNAQG protein subunit alpha q. (313 aa)
LOC105550079Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (110 aa)
USP11Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (978 aa)
DCAF7DDB1 and CUL4 associated factor 7. (342 aa)
ENSMLEP00000007417Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
TBCCTubulin folding cofactor C. (346 aa)
CSNK2A2Casein kinase 2 alpha 2; Belongs to the protein kinase superfamily. (323 aa)
ENSMLEP00000006361Uncharacterized protein. (520 aa)
LOC105544901Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
GNB3G protein subunit beta 3. (340 aa)
ERMARDER membrane associated RNA degradation. (438 aa)
VBP1Prefoldin subunit 3; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins; Belongs to the prefoldin subunit alpha family. (197 aa)
CCT7T-complex protein 1 subunit eta; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin. (543 aa)
TBCATubulin-specific chaperone A; Belongs to the TBCA family. (131 aa)
NOP56NOP56 ribonucleoprotein. (594 aa)
WRAP53WD repeat containing antisense to TP53. (531 aa)
RGS11Regulator of G protein signaling 11. (446 aa)
GNB4G protein subunit beta 4. (340 aa)
TCP1Uncharacterized protein. (556 aa)
TUBB4BTubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (373 aa)
ENSMLEP00000001951Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (60 aa)
GNA11G protein subunit alpha 11. (307 aa)
FBXW5F-box and WD repeat domain containing 5. (457 aa)
CCT3T-complex protein 1 subunit gamma. (545 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (88 aa)
FBXW9F-box and WD repeat domain containing 9. (458 aa)
CCT6BChaperonin containing TCP1 subunit 6B. (535 aa)
TUBAL3Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (446 aa)
TUBB1Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
RGS7Regulator of G protein signaling 7. (374 aa)
CCT4T-complex protein 1 subunit delta. (573 aa)
CSNK2A1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (391 aa)
TUBB2BTubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (445 aa)
FBXL3F-box and leucine rich repeat protein 3. (428 aa)
ENSMLEP00000027682Uncharacterized protein. (525 aa)
HDAC3Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (428 aa)
PDCPhosducin. (246 aa)
ENSMLEP00000028401Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (65 aa)
PFDN2Prefoldin subunit 2. (154 aa)
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
ACTBActin beta. (375 aa)
GNG5Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
LOC105549611T-complex protein 1 subunit eta; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin. (467 aa)
CCNE1Cyclin E1; Belongs to the cyclin family. (407 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
KIF13AKinesin family member 13A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1713 aa)
FBXW4F-box and WD repeat domain containing 4. (325 aa)
LOC105551879Uncharacterized protein. (447 aa)
ARL2ADP ribosylation factor like GTPase 2; Belongs to the small GTPase superfamily. Arf family. (182 aa)
ENSMLEP00000040266Uncharacterized protein. (456 aa)
GAPDHSGlyceraldehyde-3-phosphate dehydrogenase. (409 aa)
FBXW2F-box and WD repeat domain containing 2. (454 aa)
ENSMLEP00000039395Glucosylceramidase. (464 aa)
TUBA1CTubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (489 aa)
ARFGEF1ADP ribosylation factor guanine nucleotide exchange factor 1. (1816 aa)
ENSMLEP00000038971T-complex protein 1 subunit eta; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin. (459 aa)
TUBA8Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (467 aa)
FKBP10Peptidylprolyl isomerase. (582 aa)
FBXO6F-box protein 6. (293 aa)
LOC105532182Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (450 aa)
GNG13Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (67 aa)
GBAGlucosylceramidase. (533 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (402 aa)
PFDN1Prefoldin subunit 1. (122 aa)
PFDN4Prefoldin subunit 4; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins; Belongs to the prefoldin subunit beta family. (134 aa)
CSNK2BUncharacterized protein. (298 aa)
FBXO44Uncharacterized protein. (255 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
XRN25'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II. (951 aa)
CCT5Chaperonin containing TCP1 subunit 5. (503 aa)
GNGT1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
ENSMLEP00000024944Tubulin domain-containing protein. (119 aa)
ENSMLEP00000024580Uncharacterized protein. (51 aa)
TBCDTubulin folding cofactor D. (1095 aa)
TUBB6Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (390 aa)
CCT8Chaperonin containing TCP1 subunit 8. (467 aa)
GNB2G protein subunit beta 2. (340 aa)
AP3M2AP-3 complex subunit mu-2. (418 aa)
FBXL5F-box and leucine rich repeat protein 5. (673 aa)
LOC105551099Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (450 aa)
LOC105543661Uncharacterized protein. (152 aa)
CCT6AUncharacterized protein. (570 aa)
FBXW7F-box and WD repeat domain containing 7. (707 aa)
GNB5G protein subunit beta 5. (357 aa)
PFDN5Uncharacterized protein. (160 aa)
LONP2Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import. May indirectly regulate peroxisomal fatty acid beta- oxidation through degradation of the self-processed forms of TYSND1. (852 aa)
FBXO4F-box protein 4. (324 aa)
ENSMLEP00000020419Ubiquitin-like domain-containing protein. (66 aa)
TBCBTubulin folding cofactor B. (244 aa)
GNB1G protein subunit beta 1. (340 aa)
TUBB2ATubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (438 aa)
GNA15G protein subunit alpha 15. (374 aa)
CCT2Chaperonin containing TCP1 subunit 2. (535 aa)
PFDN6Prefoldin subunit 6. (129 aa)
KIFC3Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (849 aa)
RGS6Regulator of G protein signaling 6. (538 aa)
FBXW10WD_REPEATS_REGION domain-containing protein. (1038 aa)
ENSMLEP00000015708Uncharacterized protein; Belongs to the TCP-1 chaperonin family. (140 aa)
AP3M1AP-3 complex subunit mu-1; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes; Belongs to the adaptor complexes medium subunit family. (418 aa)
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
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