STRINGSTRING
GUCY1B1 GUCY1B1 GUCY1A1 GUCY1A1 GNG4 GNG4 ENSMLEP00000030524 ENSMLEP00000030524 ATP2A2 ATP2A2 PTGIR PTGIR GNG3 GNG3 GNG5 GNG5 GNG12 GNG12 ATP2B1 ATP2B1 ENSMLEP00000028684 ENSMLEP00000028684 ENSMLEP00000028401 ENSMLEP00000028401 ENSMLEP00000028290 ENSMLEP00000028290 MRVI1 MRVI1 NOS2 NOS2 TRPC6 TRPC6 REEP2 REEP2 KCNMA1 KCNMA1 KCNMB2 KCNMB2 GNGT2 GNGT2 PDE10A PDE10A ORAI3 ORAI3 GNB2 GNB2 ATP2B4 ATP2B4 PPP2R5D PPP2R5D ITPR3 ITPR3 KCNMB1 KCNMB1 REEP4 REEP4 LOC105549269 LOC105549269 PPP2CB PPP2CB PDE1A PDE1A APOB APOB ENSMLEP00000020744 ENSMLEP00000020744 P2RX2 P2RX2 GUCY1A2 GUCY1A2 GNB1 GNB1 ENSMLEP00000018038 ENSMLEP00000018038 ORAI1 ORAI1 PDE5A PDE5A ATP2B3 ATP2B3 PECAM1 PECAM1 TRPC3 TRPC3 FGR FGR STIM1 STIM1 SLC8A1 SLC8A1 REEP3 REEP3 ATP2A1 ATP2A1 LRP8 LRP8 ENSMLEP00000001760 ENSMLEP00000001760 PPP2R5E PPP2R5E ENSMLEP00000001951 ENSMLEP00000001951 ATP2B2 ATP2B2 ORAI2 ORAI2 P2RX4 P2RX4 GNB4 GNB4 PRKG1 PRKG1 GNAS GNAS P2RX1 P2RX1 PPP2R5C PPP2R5C ITPR2 ITPR2 GNB3 GNB3 PTPN11 PTPN11 LOC105551588 LOC105551588 ENSMLEP00000007417 ENSMLEP00000007417 PDE9A PDE9A PPP2R5A PPP2R5A KCNMB4 KCNMB4 GNG2 GNG2 ITPR1 ITPR1 ATP2A3 ATP2A3 PPP2R1A PPP2R1A NOS1 NOS1 ENSMLEP00000012128 ENSMLEP00000012128 ENSMLEP00000012959 ENSMLEP00000012959 PRKG2 PRKG2 NOS3 NOS3 PAFAH2 PAFAH2 PLA2G4A PLA2G4A PPP2CA PPP2CA PTPN6 PTPN6 SLC8A3 SLC8A3 TRPC7 TRPC7 GNGT1 GNGT1 P2RX3 P2RX3 PPP2R5B PPP2R5B ENSMLEP00000035415 ENSMLEP00000035415 P2RX6 P2RX6 GNG8 GNG8 SLC8A2 SLC8A2 SRI SRI PDE2A PDE2A GNG13 GNG13 MAPK14 MAPK14 P2RX7 P2RX7 PPP2R1B PPP2R1B PDE1B PDE1B PDE11A PDE11A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GUCY1B1Guanylate cyclase 1 soluble subunit beta 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (554 aa)
GUCY1A1Guanylate cyclase 1 soluble subunit alpha 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (690 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
ENSMLEP00000030524XRCC1_N domain-containing protein. (142 aa)
ATP2A2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1024 aa)
PTGIRProstaglandin I2 receptor. (386 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
GNG5Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
ATP2B1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1220 aa)
ENSMLEP00000028684P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (417 aa)
ENSMLEP00000028401Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (65 aa)
ENSMLEP00000028290Uncharacterized protein. (441 aa)
MRVI1Murine retrovirus integration site 1 homolog. (912 aa)
NOS2Nitric oxide synthase; Produces nitric oxide (NO). (1147 aa)
TRPC6Transient receptor potential cation channel subfamily C member 6; Belongs to the transient receptor (TC 1.A.4) family. (931 aa)
REEP2Receptor expression-enhancing protein. (214 aa)
KCNMA1Potassium calcium-activated channel subfamily M alpha 1. (1264 aa)
KCNMB2KcnmB2_inactiv domain-containing protein. (235 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (88 aa)
PDE10APhosphodiesterase. (779 aa)
ORAI3ORAI calcium release-activated calcium modulator 3. (295 aa)
GNB2G protein subunit beta 2. (340 aa)
ATP2B4Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1241 aa)
PPP2R5DSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (605 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2675 aa)
KCNMB1Potassium calcium-activated channel subfamily M regulatory beta subunit 1. (191 aa)
REEP4Receptor expression-enhancing protein. (257 aa)
LOC105549269TRP_2 domain-containing protein. (780 aa)
PPP2CBSerine/threonine-protein phosphatase. (275 aa)
PDE1APhosphodiesterase. (545 aa)
APOBApolipoprotein B. (4531 aa)
ENSMLEP00000020744Uncharacterized protein. (107 aa)
P2RX2Purinergic receptor P2X 2. (343 aa)
GUCY1A2Guanylate cyclase 1 soluble subunit alpha 2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (631 aa)
GNB1G protein subunit beta 1. (340 aa)
ENSMLEP00000018038Uncharacterized protein. (427 aa)
ORAI1ORAI calcium release-activated calcium modulator 1. (238 aa)
PDE5APhosphodiesterase. (875 aa)
ATP2B3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1220 aa)
PECAM1Platelet and endothelial cell adhesion molecule 1. (625 aa)
TRPC3Transient receptor potential cation channel subfamily C member 3; Belongs to the transient receptor (TC 1.A.4) family. (849 aa)
FGRTyrosine-protein kinase. (529 aa)
STIM1Stromal interaction molecule 1. (790 aa)
SLC8A1Solute carrier family 8 member A1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (973 aa)
REEP3Receptor expression-enhancing protein. (240 aa)
ATP2A1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1027 aa)
LRP8LDL receptor related protein 8. (844 aa)
ENSMLEP00000001760Uncharacterized protein. (98 aa)
PPP2R5ESerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (468 aa)
ENSMLEP00000001951Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (60 aa)
ATP2B2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1230 aa)
ORAI2ORAI calcium release-activated calcium modulator 2. (254 aa)
P2RX4P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (359 aa)
GNB4G protein subunit beta 4. (340 aa)
PRKG1cGMP-dependent protein kinase. (686 aa)
GNASGNAS complex locus. (998 aa)
P2RX1P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (399 aa)
PPP2R5CSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (580 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2663 aa)
GNB3G protein subunit beta 3. (340 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (656 aa)
LOC105551588Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (455 aa)
ENSMLEP00000007417Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
PDE9APhosphodiesterase. (570 aa)
PPP2R5ASerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (525 aa)
KCNMB4Potassium calcium-activated channel subfamily M regulatory beta subunit 4. (210 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (110 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2731 aa)
ATP2A3ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (900 aa)
PPP2R1AProtein phosphatase 2 scaffold subunit Aalpha. (589 aa)
NOS1Nitric oxide synthase; Produces nitric oxide (NO). (1404 aa)
ENSMLEP00000012128Uncharacterized protein. (234 aa)
ENSMLEP00000012959Uncharacterized protein. (3119 aa)
PRKG2cGMP-dependent protein kinase. (762 aa)
NOS3Nitric oxide synthase; Produces nitric oxide (NO). (1155 aa)
PAFAH2Platelet-activating factor acetylhydrolase. (392 aa)
PLA2G4APhospholipase A2. (749 aa)
PPP2CASerine/threonine-protein phosphatase. (275 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (623 aa)
SLC8A3Solute carrier family 8 member A3; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (927 aa)
TRPC7Transient receptor potential cation channel subfamily C member 7; Belongs to the transient receptor (TC 1.A.4) family. (863 aa)
GNGT1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
P2RX3P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (397 aa)
PPP2R5BSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (502 aa)
ENSMLEP00000035415Uncharacterized protein. (519 aa)
P2RX6P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (408 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
SLC8A2Solute carrier family 8 member A2; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (921 aa)
SRISorcin. (191 aa)
PDE2APhosphodiesterase. (953 aa)
GNG13Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (67 aa)
MAPK14Mitogen-activated protein kinase. (350 aa)
P2RX7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (595 aa)
PPP2R1BProtein phosphatase 2 scaffold subunit Abeta. (637 aa)
PDE1BPhosphodiesterase. (538 aa)
PDE11APhosphodiesterase. (933 aa)
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
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