STRINGSTRING
PRKAR1A PRKAR1A GPR25 GPR25 TAAR1 TAAR1 GPR173 GPR173 DRD5 DRD5 ENSMLEP00000001951 ENSMLEP00000001951 GPBAR1 GPBAR1 POMC POMC THAP6 THAP6 ADCY4 ADCY4 LHCGR LHCGR GPR20 GPR20 PDE3A PDE3A GNB4 GNB4 ADRB2 ADRB2 CRHR1 CRHR1 GRK5 GRK5 ADCY9 ADCY9 ADCY7 ADCY7 CALCR CALCR GNAS GNAS VIPR1 VIPR1 LOC105548555 LOC105548555 CRH CRH ADCYAP1R1 ADCYAP1R1 ADCY8 ADCY8 PTGDR PTGDR TAAR5 TAAR5 LOC105535058 LOC105535058 CALCRL CALCRL GNAI2 GNAI2 MC4R MC4R GNB3 GNB3 GPR15 GPR15 GPR45 GPR45 TAAR6 TAAR6 ADM ADM ENSMLEP00000006827 ENSMLEP00000006827 PDE4D PDE4D GPR63 GPR63 THAP7 THAP7 LOC105548556 LOC105548556 ENSMLEP00000007417 ENSMLEP00000007417 PTH2 PTH2 DRD1 DRD1 GNG2 GNG2 LOC105550079 LOC105550079 ADORA2A ADORA2A ENSMLEP00000009558 ENSMLEP00000009558 VIPR2 VIPR2 SCTR SCTR FAM83G FAM83G PRKAR1B PRKAR1B RAMP1 RAMP1 GPHA2 GPHA2 PTGER4 PTGER4 HTR7 HTR7 ARRB2 ARRB2 PDE4A PDE4A GNAT3 GNAT3 GPR39 GPR39 GRK6 GRK6 NPS NPS FAP FAP GPR83 GPR83 ENSMLEP00000016272 ENSMLEP00000016272 PTH1R PTH1R ADCY2 ADCY2 PTGER2 PTGER2 HTR4 HTR4 GIP GIP P2RY11 P2RY11 GHRHR GHRHR GNB1 GNB1 HRH2 HRH2 PRKACA PRKACA PDE7A PDE7A GRK2 GRK2 GLP2R GLP2R TAAR2 TAAR2 FSHR FSHR PDE1A PDE1A PTHLH PTHLH TAAR8 TAAR8 ADM2 ADM2 GHRH GHRH GCG GCG RXFP1 RXFP1 GRK3 GRK3 PTH PTH GPHB5 GPHB5 GNB2 GNB2 ADCY1 ADCY1 GNAZ GNAZ ENSMLEP00000024790 ENSMLEP00000024790 PDE10A PDE10A ADCY5 ADCY5 ITGA5 ITGA5 ARR3 ARR3 GNGT2 GNGT2 FSHB FSHB GNAI3 GNAI3 GCGR GCGR CALCB CALCB PTH2R PTH2R ADCY3 ADCY3 RAMP2 RAMP2 FN1 FN1 ENSMLEP00000027485 ENSMLEP00000027485 PDE7B PDE7B ENSMLEP00000028401 ENSMLEP00000028401 ADORA2B ADORA2B ITGB1 ITGB1 GNG12 GNG12 ARRB1 ARRB1 GNG5 GNG5 GNG3 GNG3 PTGIR PTGIR PRKAR2A PRKAR2A RAMP3 RAMP3 RLN2 RLN2 GNG4 GNG4 GPR32 GPR32 PRKAR2B PRKAR2B PDE8B PDE8B PRKACB PRKACB GLP1R GLP1R HTR6 HTR6 TSHB TSHB GNGT1 GNGT1 ADCYAP1 ADCYAP1 GNAI1 GNAI1 PDE8A PDE8A CNBD2 CNBD2 SRC SRC GNG8 GNG8 ENSMLEP00000035658 ENSMLEP00000035658 SHC1 SHC1 IAPP IAPP GPR176 GPR176 GPER1 GPER1 PDE2A PDE2A GNG13 GNG13 AVPR2 AVPR2 ADCY6 ADCY6 PDE4C PDE4C RLN3 RLN3 PDE1B PDE1B GIPR GIPR CRHR2 CRHR2 PDE3B PDE3B TSHR TSHR RXFP2 RXFP2 CALCA CALCA PDE11A PDE11A NPSR1 NPSR1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PRKAR1AUncharacterized protein. (381 aa)
GPR25G protein-coupled receptor 25; Belongs to the G-protein coupled receptor 1 family. (361 aa)
TAAR1Trace amine associated receptor 1; Belongs to the G-protein coupled receptor 1 family. (339 aa)
GPR173G protein-coupled receptor 173. (373 aa)
DRD5Dopamine receptor D5; Belongs to the G-protein coupled receptor 1 family. (478 aa)
ENSMLEP00000001951Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (60 aa)
GPBAR1G protein-coupled bile acid receptor 1. (330 aa)
POMCProopiomelanocortin. (265 aa)
THAP6THAP domain containing 6. (221 aa)
ADCY4Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
LHCGRLutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (657 aa)
GPR20G protein-coupled receptor 20; Belongs to the G-protein coupled receptor 1 family. (359 aa)
PDE3APhosphodiesterase. (1054 aa)
GNB4G protein subunit beta 4. (340 aa)
ADRB2Adrenoceptor beta 2. (415 aa)
CRHR1Corticotropin releasing hormone receptor 1; Belongs to the G-protein coupled receptor 2 family. (433 aa)
GRK5G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (590 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1082 aa)
CALCRCalcitonin receptor; Belongs to the G-protein coupled receptor 2 family. (489 aa)
GNASGNAS complex locus. (998 aa)
VIPR1Vasoactive intestinal peptide receptor 1; Belongs to the G-protein coupled receptor 2 family. (440 aa)
LOC105548555G_PROTEIN_RECEP_F1_2 domain-containing protein. (396 aa)
CRHCorticotropin releasing hormone. (196 aa)
ADCYAP1R1ADCYAP receptor type I; Belongs to the G-protein coupled receptor 2 family. (523 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1251 aa)
PTGDRProstaglandin D2 receptor. (359 aa)
TAAR5Trace amine associated receptor 5; Belongs to the G-protein coupled receptor 1 family. (337 aa)
LOC105535058G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (343 aa)
CALCRLCalcitonin receptor like receptor; Belongs to the G-protein coupled receptor 2 family. (461 aa)
GNAI2G protein subunit alpha i2. (352 aa)
MC4RMelanocortin 4 receptor. (332 aa)
GNB3G protein subunit beta 3. (340 aa)
GPR15G protein-coupled receptor 15; Belongs to the G-protein coupled receptor 1 family. (360 aa)
GPR45G protein-coupled receptor 45. (372 aa)
TAAR6Trace amine associated receptor 6; Belongs to the G-protein coupled receptor 1 family. (345 aa)
ADMAdrenomedullin. (200 aa)
ENSMLEP00000006827G_PROTEIN_RECEP_F1_2 domain-containing protein. (178 aa)
PDE4DPhosphodiesterase. (748 aa)
GPR63G protein-coupled receptor 63. (419 aa)
THAP7THAP domain containing 7. (309 aa)
LOC105548556G_PROTEIN_RECEP_F1_2 domain-containing protein. (396 aa)
ENSMLEP00000007417Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
PTH2Parathyroid hormone 2. (98 aa)
DRD1Dopamine receptor D1; Belongs to the G-protein coupled receptor 1 family. (446 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (110 aa)
LOC105550079Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
ADORA2AAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (412 aa)
ENSMLEP00000009558G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (279 aa)
VIPR2Vasoactive intestinal peptide receptor 2; Belongs to the G-protein coupled receptor 2 family. (499 aa)
SCTRSecretin receptor; Belongs to the G-protein coupled receptor 2 family. (443 aa)
FAM83GFamily with sequence similarity 83 member G. (823 aa)
PRKAR1BProtein kinase cAMP-dependent type I regulatory subunit beta. (381 aa)
RAMP1Receptor activity modifying protein 1. (130 aa)
GPHA2Glycoprotein hormone subunit alpha 2. (127 aa)
PTGER4Prostaglandin E receptor 4; Belongs to the G-protein coupled receptor 1 family. (470 aa)
HTR75-hydroxytryptamine receptor 7. (432 aa)
ARRB2Arrestin beta 2. (478 aa)
PDE4APhosphodiesterase 4A; Belongs to the cyclic nucleotide phosphodiesterase family. (766 aa)
GNAT3G protein subunit alpha transducin 3. (354 aa)
GPR39G protein-coupled receptor 39; Belongs to the G-protein coupled receptor 1 family. (450 aa)
GRK6G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (597 aa)
NPSNeuropeptide S. (89 aa)
FAPFibroblast activation protein alpha; Belongs to the peptidase S9B family. (760 aa)
GPR83G protein-coupled receptor 83; Belongs to the G-protein coupled receptor 1 family. (423 aa)
ENSMLEP00000016272Uncharacterized protein. (374 aa)
PTH1RParathyroid hormone 1 receptor; Belongs to the G-protein coupled receptor 2 family. (782 aa)
ADCY2Adenylate cyclase 2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (901 aa)
PTGER2Prostaglandin E receptor 2; Belongs to the G-protein coupled receptor 1 family. (358 aa)
HTR45-hydroxytryptamine receptor 4; Belongs to the G-protein coupled receptor 1 family. (428 aa)
GIPGastric inhibitory polypeptide. (150 aa)
P2RY11Purinergic receptor P2Y11; Belongs to the G-protein coupled receptor 1 family. (374 aa)
GHRHRGrowth hormone releasing hormone receptor; Belongs to the G-protein coupled receptor 2 family. (423 aa)
GNB1G protein subunit beta 1. (340 aa)
HRH2Histamine receptor H2; Belongs to the G-protein coupled receptor 1 family. (422 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (352 aa)
PDE7APhosphodiesterase. (458 aa)
GRK2G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (701 aa)
GLP2RGlucagon like peptide 2 receptor; Belongs to the G-protein coupled receptor 2 family. (553 aa)
TAAR2Trace amine associated receptor 2 (gene/pseudogene); Belongs to the G-protein coupled receptor 1 family. (350 aa)
FSHRFollicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. (695 aa)
PDE1APhosphodiesterase. (545 aa)
PTHLHParathyroid hormone like hormone. (209 aa)
TAAR8Trace amine associated receptor 8; Belongs to the G-protein coupled receptor 1 family. (281 aa)
ADM2Adrenomedullin 2. (145 aa)
GHRHGrowth hormone releasing hormone. (108 aa)
GCGGlucagon. (180 aa)
RXFP1Relaxin family peptide receptor 1. (779 aa)
GRK3G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (669 aa)
PTHParathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family. (115 aa)
GPHB5Glycoprotein hormone subunit beta 5. (130 aa)
GNB2G protein subunit beta 2. (340 aa)
ADCY1Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (338 aa)
GNAZG protein subunit alpha z. (355 aa)
ENSMLEP00000024790Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (294 aa)
PDE10APhosphodiesterase. (779 aa)
ADCY5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1064 aa)
ITGA5Integrin subunit alpha 5; Belongs to the integrin alpha chain family. (1053 aa)
ARR3Arrestin 3. (389 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (88 aa)
FSHBFollicle stimulating hormone subunit beta. (129 aa)
GNAI3G protein subunit alpha i3. (354 aa)
GCGRGlucagon receptor; Belongs to the G-protein coupled receptor 2 family. (491 aa)
CALCBCalcitonin related polypeptide beta. (138 aa)
PTH2RParathyroid hormone 2 receptor; Belongs to the G-protein coupled receptor 2 family. (550 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1146 aa)
RAMP2Receptor activity modifying protein 2. (216 aa)
FN1Fibronectin 1. (2384 aa)
ENSMLEP00000027485PID domain-containing protein. (488 aa)
PDE7BPhosphodiesterase. (505 aa)
ENSMLEP00000028401Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (65 aa)
ADORA2BAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (331 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (748 aa)
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
ARRB1Arrestin beta 1. (417 aa)
GNG5Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
PTGIRProstaglandin I2 receptor. (386 aa)
PRKAR2AUncharacterized protein. (211 aa)
RAMP3Receptor activity modifying protein 3. (151 aa)
RLN2Relaxin 2. (185 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
GPR32G protein-coupled receptor 32; Belongs to the G-protein coupled receptor 1 family. (346 aa)
PRKAR2BProtein kinase cAMP-dependent type II regulatory subunit beta. (378 aa)
PDE8BPhosphodiesterase. (798 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
GLP1RGlucagon like peptide 1 receptor; Belongs to the G-protein coupled receptor 2 family. (463 aa)
HTR65-hydroxytryptamine receptor 6; Belongs to the G-protein coupled receptor 1 family. (414 aa)
TSHBThyroid stimulating hormone subunit beta. (138 aa)
GNGT1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
ADCYAP1Adenylate cyclase activating polypeptide 1. (176 aa)
GNAI1G protein subunit alpha i1. (314 aa)
PDE8APhosphodiesterase. (794 aa)
CNBD2Cyclic nucleotide binding domain containing 2. (577 aa)
SRCTyrosine-protein kinase. (542 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
ENSMLEP00000035658Uncharacterized protein. (111 aa)
SHC1SHC adaptor protein 1. (584 aa)
IAPPIslet amyloid polypeptide. (89 aa)
GPR176G protein-coupled receptor 176. (515 aa)
GPER1G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (400 aa)
PDE2APhosphodiesterase. (953 aa)
GNG13Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (67 aa)
AVPR2Vasopressin V2 receptor; Involved in renal water reabsorption. Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (368 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1168 aa)
PDE4CPhosphodiesterase. (612 aa)
RLN3Relaxin 3. (142 aa)
PDE1BPhosphodiesterase. (538 aa)
GIPRGastric inhibitory polypeptide receptor; Belongs to the G-protein coupled receptor 2 family. (433 aa)
CRHR2Corticotropin releasing hormone receptor 2; Belongs to the G-protein coupled receptor 2 family. (431 aa)
PDE3BPhosphodiesterase. (1113 aa)
TSHRThyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (764 aa)
RXFP2Relaxin family peptide receptor 2. (746 aa)
CALCACalcitonin related polypeptide alpha. (140 aa)
PDE11APhosphodiesterase. (933 aa)
NPSR1Neuropeptide S receptor 1; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (391 aa)
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
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