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| | AGER | Advanced glycosylation end-product specific receptor. (403 aa) |
| | RPS27A | Ubiquitin-like domain-containing protein. (138 aa) |
| | ENSMLEP00000000931 | MPN domain-containing protein. (299 aa) |
| | ENSMLEP00000001074 | Uncharacterized protein. (172 aa) |
| | PELI3 | E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (469 aa) |
| | UBE2NL | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (89 aa) |
| | MAP3K3 | Mitogen-activated protein kinase kinase kinase 3. (659 aa) |
| | PSMD13 | Proteasome 26S subunit, non-ATPase 13. (351 aa) |
| | NKIRAS2 | NFKB inhibitor interacting Ras like 2. (207 aa) |
| | PSMB9 | Proteasome subunit beta. (196 aa) |
| | TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (522 aa) |
| | PSME3 | Proteasome activator subunit 3. (267 aa) |
| | IL36B | Interleukin 36 beta. (164 aa) |
| | PSMB11 | Proteasome subunit beta. (300 aa) |
| | PTPN5 | Protein tyrosine phosphatase non-receptor type 5. (566 aa) |
| | PSMA4 | Proteasome subunit alpha type. (261 aa) |
| | IL1RN | Interleukin-1. (159 aa) |
| | PSMB4 | Proteasome subunit beta; Belongs to the peptidase T1B family. (274 aa) |
| | LOC105541098 | Ubiquitin-like domain-containing protein. (156 aa) |
| | PSMB6 | Proteasome subunit beta. (242 aa) |
| | IL13 | Interleukin 13. (146 aa) |
| | ENSMLEP00000005424 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (142 aa) |
| | PSMC5 | Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa) |
| | ENSMLEP00000005586 | ATPase_AAA_core domain-containing protein; Belongs to the AAA ATPase family. (179 aa) |
| | PSMB3 | Proteasome subunit beta. (205 aa) |
| | NFKB2 | Nuclear factor kappa B subunit 2. (900 aa) |
| | IL1RL1 | Interleukin 1 receptor like 1. (556 aa) |
| | TIFA | TRAF interacting protein with forkhead associated domain. (185 aa) |
| | ENSMLEP00000006240 | Ubiquitin-like domain-containing protein. (127 aa) |
| | MAPK10 | Mitogen-activated protein kinase. (477 aa) |
| | ENSMLEP00000006413 | AAA domain-containing protein; Belongs to the AAA ATPase family. (423 aa) |
| | PTPN11 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (656 aa) |
| | LRRC14 | Leucine rich repeat containing 14. (493 aa) |
| | MFSD1 | Major facilitator superfamily domain containing 1. (514 aa) |
| | LOC105540679 | UBIQUITIN_CONJUGAT_2 domain-containing protein. (147 aa) |
| | GSDMD | Gasdermin D. (532 aa) |
| | SKP1 | S-phase kinase associated protein 1; Belongs to the SKP1 family. (165 aa) |
| | PELI1 | E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (418 aa) |
| | LOC105536598 | Ubiquitin-like domain-containing protein. (156 aa) |
| | ENSMLEP00000008311 | Uncharacterized protein; Belongs to the SKP1 family. (142 aa) |
| | LOC105548744 | Serum amyloid A protein; Major acute phase reactant. Apolipoprotein of the HDL complex. (122 aa) |
| | PSMB1 | Proteasome subunit beta. (241 aa) |
| | IL18R1 | Interleukin 18 receptor 1. (540 aa) |
| | PSMB8 | Proteasome subunit beta. (276 aa) |
| | LOC105548749 | Serum amyloid A protein; Major acute phase reactant. Apolipoprotein of the HDL complex. (122 aa) |
| | IL1RAP | Interleukin 1 receptor accessory protein. (687 aa) |
| | PTPN23 | Protein tyrosine phosphatase non-receptor type 23. (1634 aa) |
| | IRAK1 | Interleukin 1 receptor associated kinase 1. (610 aa) |
| | PTPN13 | Protein tyrosine phosphatase non-receptor type 13. (2092 aa) |
| | PSMD9 | PDZ domain-containing protein. (223 aa) |
| | USP14 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (491 aa) |
| | PELI2 | Pellino E3 ubiquitin protein ligase family member 2. (394 aa) |
| | ENSMLEP00000011388 | Ubiquitin-like domain-containing protein. (120 aa) |
| | IL1RAPL1 | Interleukin 1 receptor accessory protein like 1. (437 aa) |
| | ENSMLEP00000012128 | Uncharacterized protein. (234 aa) |
| | PSMD5 | Proteasome 26S subunit, non-ATPase 5. (508 aa) |
| | NLRP6 | NLR family pyrin domain containing 6. (1044 aa) |
| | STAT3 | Signal transducer and activator of transcription. (693 aa) |
| | LOC105534146 | Uncharacterized protein; Belongs to the peptidase C14A family. (410 aa) |
| | NFKB1 | Nuclear factor kappa B subunit 1. (969 aa) |
| | PSMA1 | Proteasome subunit alpha type. (269 aa) |
| | LOC105532112 | Uncharacterized protein. (188 aa) |
| | S100B | S_100 domain-containing protein; Belongs to the S-100 family. (94 aa) |
| | PSMA2 | Proteasome subunit alpha type. (234 aa) |
| | N4BP1 | NEDD4 binding protein 1. (863 aa) |
| | IRAK4 | Interleukin 1 receptor associated kinase 4. (460 aa) |
| | LOC105534152 | Uncharacterized protein; Belongs to the peptidase C14A family. (352 aa) |
| | NLRX1 | NLR family member X1. (972 aa) |
| | MAP2K6 | Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (335 aa) |
| | PTPN6 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (623 aa) |
| | IL1A | Interleukin-1; Belongs to the IL-1 family. (271 aa) |
| | ENSMLEP00000015464 | Uncharacterized protein. (189 aa) |
| | MYD88 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (317 aa) |
| | MAPK8 | Mitogen-activated protein kinase. (427 aa) |
| | TOLLIP | Toll interacting protein. (274 aa) |
| | CASP8 | Caspase 8; Belongs to the peptidase C14A family. (479 aa) |
| | IL18BP | Interleukin 18 binding protein. (207 aa) |
| | LRRC31 | Leucine rich repeat containing 31. (496 aa) |
| | PSMD10 | Proteasome 26S subunit, non-ATPase 10. (226 aa) |
| | IL18RAP | Interleukin 18 receptor accessory protein. (598 aa) |
| | ENSMLEP00000016378 | AAA domain-containing protein. (201 aa) |
| | ENSMLEP00000016528 | Uncharacterized protein. (191 aa) |
| | IL1R1 | Interleukin 1 receptor type 1. (569 aa) |
| | ENSMLEP00000016609 | Uncharacterized protein. (174 aa) |
| | LOC105548751 | Serum amyloid A protein; Major acute phase reactant. Apolipoprotein of the HDL complex. (130 aa) |
| | ENSMLEP00000016698 | AAA domain-containing protein; Belongs to the AAA ATPase family. (390 aa) |
| | SMAD3 | Mothers against decapentaplegic homolog. (425 aa) |
| | CASP12 | Caspase 12 (gene/pseudogene); Belongs to the peptidase C14A family. (421 aa) |
| | PSMD4 | Proteasome 26S subunit, non-ATPase 4. (378 aa) |
| | IKBKB | Inhibitor of nuclear factor kappa B kinase subunit beta. (706 aa) |
| | IL36A | Interleukin-1. (158 aa) |
| | PSMC3 | AAA domain-containing protein; Belongs to the AAA ATPase family. (446 aa) |
| | PTPN14 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily. (1187 aa) |
| | IL18 | Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (193 aa) |
| | ENSMLEP00000018394 | UBIQUITIN_CONJUGAT_2 domain-containing protein. (129 aa) |
| | PTPN9 | Protein tyrosine phosphatase non-receptor type 9. (590 aa) |
| | PSMA5 | Proteasome subunit alpha type. (241 aa) |
| | IRAK3 | Interleukin 1 receptor associated kinase 3. (582 aa) |
| | CARD16 | Caspase recruitment domain family member 16. (196 aa) |
| | PSMA7 | Proteasome endopeptidase complex. (178 aa) |
| | PSMF1 | Proteasome inhibitor subunit 1. (271 aa) |
| | LOC105545975 | Uncharacterized protein. (448 aa) |
| | ENSMLEP00000019789 | ANK_REP_REGION domain-containing protein. (165 aa) |
| | KHNYN | KH and NYN domain containing. (678 aa) |
| | MAP2K1 | Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa) |
| | SIGIRR | Single Ig and TIR domain containing. (475 aa) |
| | PTPN7 | Protein tyrosine phosphatase non-receptor type 7. (465 aa) |
| | PSMD11 | Proteasome 26S subunit, non-ATPase 11. (357 aa) |
| | PSMB7 | Proteasome subunit beta. (302 aa) |
| | ALOX5 | Arachidonate 5-lipoxygenase. (674 aa) |
| | TNIP2 | TNFAIP3 interacting protein 2. (322 aa) |
| | PSMD12 | Proteasome 26S subunit, non-ATPase 12. (456 aa) |
| | NOD1 | Nucleotide binding oligomerization domain containing 1. (961 aa) |
| | LOC105536463 | AAA domain-containing protein; Belongs to the AAA ATPase family. (366 aa) |
| | FBXW11 | F-box and WD repeat domain containing 11. (546 aa) |
| | MAP3K20 | Mitogen-activated protein kinase kinase kinase 20. (800 aa) |
| | ENSMLEP00000022706 | Zf-rbx1 domain-containing protein. (93 aa) |
| | S100A12 | S100 calcium binding protein A12; Belongs to the S-100 family. (90 aa) |
| | CASP1 | Caspase 1; Belongs to the peptidase C14A family. (404 aa) |
| | TBK1 | TANK binding kinase 1. (729 aa) |
| | PSMD1 | 26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa) |
| | PSMD2 | 26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (888 aa) |
| | LOC105539754 | CCHC NOA-type domain-containing protein. (361 aa) |
| | CHUK | Component of inhibitor of nuclear factor kappa B kinase complex. (745 aa) |
| | ENSMLEP00000024034 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (142 aa) |
| | TAB1 | TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (504 aa) |
| | RIPK2 | Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (540 aa) |
| | IRAK2 | Interleukin 1 receptor associated kinase 2. (625 aa) |
| | NLRP9 | NLR family pyrin domain containing 9. (873 aa) |
| | ENSMLEP00000024603 | UBIQUITIN_CONJUGAT_2 domain-containing protein. (102 aa) |
| | PSMD8 | Proteasome 26S subunit, non-ATPase 8. (350 aa) |
| | IL1B | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (268 aa) |
| | ENSMLEP00000024805 | Protein kinase domain-containing protein. (365 aa) |
| | NOD2 | Nucleotide binding oligomerization domain containing 2. (1012 aa) |
| | ENSMLEP00000025123 | CSN8_PSD8_EIF3K domain-containing protein. (254 aa) |
| | PTPN12 | Tyrosine-protein phosphatase non-receptor type 12; Dephosphorylates a range of proteins, and thereby regulates cellular signaling cascades. (661 aa) |
| | PSME4 | Proteasome activator subunit 4. (1795 aa) |
| | NKIRAS1 | NFKB inhibitor interacting Ras like 1. (192 aa) |
| | NLRP13 | NLR family pyrin domain containing 13. (937 aa) |
| | HMGB1 | High mobility group box 1. (215 aa) |
| | BTRC | Beta-transducin repeat containing E3 ubiquitin protein ligase. (605 aa) |
| | NFKBIA | ANK_REP_REGION domain-containing protein. (305 aa) |
| | PSME1 | Proteasome activator subunit 1. (284 aa) |
| | CTSG | Cathepsin G; Belongs to the peptidase S1 family. (255 aa) |
| | SQSTM1 | Sequestosome 1. (374 aa) |
| | ENSMLEP00000026884 | Uncharacterized protein. (211 aa) |
| | IL37 | Interleukin-1. (214 aa) |
| | IL33 | Interleukin 33. (270 aa) |
| | IL36RN | Interleukin-1. (155 aa) |
| | PSMC1 | Proteasome 26S subunit, ATPase 1; Belongs to the AAA ATPase family. (440 aa) |
| | NFKBIB | NFKB inhibitor beta. (286 aa) |
| | PTPN18 | Protein tyrosine phosphatase non-receptor type 18. (425 aa) |
| | IL36G | Interleukin-1. (134 aa) |
| | ENSMLEP00000027531 | KIND domain-containing protein. (226 aa) |
| | PSMC4 | Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa) |
| | IL1F10 | Interleukin-1. (152 aa) |
| | ENSMLEP00000028290 | Uncharacterized protein. (441 aa) |
| | LRRC71 | Leucine rich repeat containing 71. (559 aa) |
| | PSMA6 | Proteasome subunit alpha type. (252 aa) |
| | TAB3 | TGF-beta activated kinase 1 (MAP3K7) binding protein 3. (712 aa) |
| | ENSMLEP00000029127 | FERM domain-containing protein. (117 aa) |
| | UBA52 | Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa) |
| | PTPN2 | Tyrosine-protein phosphatase non-receptor type. (403 aa) |
| | IL4 | Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Belongs to the IL-4/IL-13 family. (153 aa) |
| | MAP3K7 | Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa) |
| | TAB2 | TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (693 aa) |
| | ALPK1 | Alpha kinase 1. (1244 aa) |
| | PSMC6 | AAA domain-containing protein; Belongs to the AAA ATPase family. (403 aa) |
| | PSMD3 | Proteasome 26S subunit, non-ATPase 3. (534 aa) |
| | NLRP12 | NLR family pyrin domain containing 12. (1031 aa) |
| | APP | Amyloid beta precursor protein. (772 aa) |
| | PSMB10 | Proteasome subunit beta. (273 aa) |
| | VWC2 | Von Willebrand factor C domain containing 2. (212 aa) |
| | PTPN4 | Tyrosine-protein phosphatase non-receptor type; May act at junctions between the membrane and the cytoskeleton. (926 aa) |
| | PSMC2 | Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (467 aa) |
| | MAP2K4 | Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (373 aa) |
| | IL1R2 | Interleukin 1 receptor type 2. (398 aa) |
| | LRRC74A | Leucine rich repeat containing 74A. (488 aa) |
| | LRRC34 | Leucine rich repeat containing 34. (421 aa) |
| | PSMB2 | Proteasome subunit beta. (201 aa) |
| | ENSMLEP00000034242 | Uncharacterized protein. (173 aa) |
| | PSME2 | Proteasome activator subunit 2. (239 aa) |
| | TONSL | Tonsoku like, DNA repair protein. (1350 aa) |
| | ENSMLEP00000035415 | Uncharacterized protein. (519 aa) |
| | RELA | RELA proto-oncogene, NF-kB subunit. (550 aa) |
| | PSMA3 | Proteasome subunit alpha type. (255 aa) |
| | NLRC5 | NLR family CARD domain containing 5. (1866 aa) |
| | PSMA8 | Proteasome subunit alpha type. (250 aa) |
| | ENSMLEP00000036559 | Uncharacterized protein. (336 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (402 aa) |
| | TRAF2 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa) |
| | ENSMLEP00000037519 | Uncharacterized protein. (87 aa) |
| | PSMB5 | Proteasome subunit beta. (263 aa) |
| | MAP3K8 | Mitogen-activated protein kinase kinase kinase 8. (467 aa) |
| | PSMD7 | Proteasome 26S subunit, non-ATPase 7. (324 aa) |
| | ENSMLEP00000038111 | Proteasome endopeptidase complex. (222 aa) |
| | ENSMLEP00000038668 | Prot_ATP_ID_OB domain-containing protein. (166 aa) |
| | PSMD14 | Proteasome 26S subunit, non-ATPase 14. (315 aa) |
| | PTPN20 | Protein tyrosine phosphatase non-receptor type 20. (420 aa) |
| | PSMD6 | Proteasome 26S subunit, non-ATPase 6. (442 aa) |
| | MAP3K2 | Mitogen-activated protein kinase kinase kinase 2. (619 aa) |
| | IL1RL2 | Interleukin 1 receptor like 2. (575 aa) |
| | RBX1 | RING-type domain-containing protein. (108 aa) |
| | CUL1 | Cullin 1; Belongs to the cullin family. (776 aa) |
