29 items (Mandrillus leucophaeus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	VAV1	Vav guanine nucleotide exchange factor 1. (766 aa)
	MTOR	Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa)
	PAK2	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (477 aa)
	CDH5	Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. (705 aa)
	CTNNB1	Catenin beta 1. (781 aa)
	VAV3	Vav guanine nucleotide exchange factor 3. (875 aa)
	CAV1	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (147 aa)
	VAV2	Vav guanine nucleotide exchange factor 2. (787 aa)
	PDPK1	3-phosphoinositide dependent protein kinase 1. (529 aa)
	JUP	Junction plakoglobin. (745 aa)
	NOS3	Nitric oxide synthase; Produces nitric oxide (NO). (1155 aa)
	LOC105532771	Uncharacterized protein. (665 aa)
	PAK1	Non-specific serine/threonine protein kinase. (545 aa)
	ARVCF	ARVCF delta catenin family member. (962 aa)
	AKT2	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
	RICTOR	RPTOR independent companion of MTOR complex 2. (1699 aa)
	STX7	Syntaxin 7; Belongs to the syntaxin family. (261 aa)
	AKT1	Non-specific serine/threonine protein kinase. (432 aa)
	STX12	Syntaxin 12; Belongs to the syntaxin family. (276 aa)
	MLST8	MTOR associated protein, LST8 homolog. (335 aa)
	PRR5	Proline rich 5. (384 aa)
	PAK3	P21 (RAC1) activated kinase 3. (580 aa)
	HSP90AA1	Heat shock protein 90 alpha family class A member 1. (823 aa)
	TRIB3	Tribbles pseudokinase 3. (385 aa)
	THEM4	Thioesterase superfamily member 4. (240 aa)
	CTNND1	Catenin delta 1. (968 aa)
	AKT3	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
	CTNNA1	Catenin alpha 1. (906 aa)
	MAPKAP1	MAPK associated protein 1. (522 aa)

Your Current Organism:

Mandrillus leucophaeus

NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKT1	AKT2	ENSMLEP00000027863	ENSMLEP00000021914	Non-specific serine/threonine protein kinase.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.967
AKT1	AKT3	ENSMLEP00000027863	ENSMLEP00000036989	Non-specific serine/threonine protein kinase.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.914
AKT1	CAV1	ENSMLEP00000027863	ENSMLEP00000009962	Non-specific serine/threonine protein kinase.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.463
AKT1	CTNNB1	ENSMLEP00000027863	ENSMLEP00000009207	Non-specific serine/threonine protein kinase.	Catenin beta 1.	0.766
AKT1	HSP90AA1	ENSMLEP00000027863	ENSMLEP00000032859	Non-specific serine/threonine protein kinase.	Heat shock protein 90 alpha family class A member 1.	0.987
AKT1	JUP	ENSMLEP00000027863	ENSMLEP00000014041	Non-specific serine/threonine protein kinase.	Junction plakoglobin.	0.561
AKT1	MAPKAP1	ENSMLEP00000027863	ENSMLEP00000039915	Non-specific serine/threonine protein kinase.	MAPK associated protein 1.	0.873
AKT1	MLST8	ENSMLEP00000027863	ENSMLEP00000029859	Non-specific serine/threonine protein kinase.	MTOR associated protein, LST8 homolog.	0.736
AKT1	MTOR	ENSMLEP00000027863	ENSMLEP00000005374	Non-specific serine/threonine protein kinase.	Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family.	0.992
AKT1	NOS3	ENSMLEP00000027863	ENSMLEP00000014301	Non-specific serine/threonine protein kinase.	Nitric oxide synthase; Produces nitric oxide (NO).	0.976
AKT1	PAK1	ENSMLEP00000027863	ENSMLEP00000018772	Non-specific serine/threonine protein kinase.	Non-specific serine/threonine protein kinase.	0.737
AKT1	PAK3	ENSMLEP00000027863	ENSMLEP00000032480	Non-specific serine/threonine protein kinase.	P21 (RAC1) activated kinase 3.	0.453
AKT1	PDPK1	ENSMLEP00000027863	ENSMLEP00000011703	Non-specific serine/threonine protein kinase.	3-phosphoinositide dependent protein kinase 1.	0.989
AKT1	RICTOR	ENSMLEP00000027863	ENSMLEP00000024740	Non-specific serine/threonine protein kinase.	RPTOR independent companion of MTOR complex 2.	0.950
AKT1	THEM4	ENSMLEP00000027863	ENSMLEP00000035456	Non-specific serine/threonine protein kinase.	Thioesterase superfamily member 4.	0.997
AKT1	TRIB3	ENSMLEP00000027863	ENSMLEP00000034910	Non-specific serine/threonine protein kinase.	Tribbles pseudokinase 3.	0.958
AKT1	VAV1	ENSMLEP00000027863	ENSMLEP00000010686	Non-specific serine/threonine protein kinase.	Vav guanine nucleotide exchange factor 1.	0.553
AKT1	VAV2	ENSMLEP00000027863	ENSMLEP00000010369	Non-specific serine/threonine protein kinase.	Vav guanine nucleotide exchange factor 2.	0.450
AKT1	VAV3	ENSMLEP00000027863	ENSMLEP00000009261	Non-specific serine/threonine protein kinase.	Vav guanine nucleotide exchange factor 3.	0.553
AKT2	AKT1	ENSMLEP00000021914	ENSMLEP00000027863	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase.	0.967