STRINGSTRING
LOC105533249 LOC105533249 ENSMLEP00000040085 ENSMLEP00000040085 COX5A COX5A LRPPRC LRPPRC GLS GLS COX8A COX8A DESI1 DESI1 RHEBL1 RHEBL1 LOC105534886 LOC105534886 ENSMLEP00000037960 ENSMLEP00000037960 GLS2 GLS2 PRDX1 PRDX1 TP53 TP53 AKT3 AKT3 LOC105533155 LOC105533155 TXNRD3 TXNRD3 COX6B2 COX6B2 LAMTOR5 LAMTOR5 TNRC6B TNRC6B NME9 NME9 LOC105537866 LOC105537866 ENSMLEP00000034545 ENSMLEP00000034545 PRKAA1 PRKAA1 DDIT4 DDIT4 RRAGC RRAGC PRKAB2 PRKAB2 LOC105538345 LOC105538345 KIAA1671 KIAA1671 G6PD G6PD TIGAR TIGAR LOC105528871 LOC105528871 PRKAG1 PRKAG1 COX6A2 COX6A2 ENSMLEP00000032494 ENSMLEP00000032494 ENSMLEP00000032441 ENSMLEP00000032441 NPVF NPVF CRYBB3 CRYBB3 RPTOR RPTOR GATC GATC YWHAB YWHAB AGO4 AGO4 DESI2 DESI2 COX7B COX7B TSC2 TSC2 MLST8 MLST8 AGO2 AGO2 ENSMLEP00000028979 ENSMLEP00000028979 COX11 COX11 AGO1 AGO1 LAMTOR4 LAMTOR4 ENSMLEP00000028457 ENSMLEP00000028457 AKT1 AKT1 PRKAG2 PRKAG2 ENSMLEP00000027047 ENSMLEP00000027047 LAMTOR1 LAMTOR1 TACO1 TACO1 PTEN PTEN TSC1 TSC1 LOC105528170 LOC105528170 LOC105544325 LOC105544325 PRDX5 PRDX5 CRYGN CRYGN SESN2 SESN2 DDIT4L DDIT4L YWHAH YWHAH ENSMLEP00000022340 ENSMLEP00000022340 AKT2 AKT2 LAMTOR3 LAMTOR3 COX6C COX6C SLC38A9 SLC38A9 COX20 COX20 ENSMLEP00000019251 ENSMLEP00000019251 YWHAE YWHAE YWHAZ YWHAZ ENSMLEP00000017703 ENSMLEP00000017703 NME8 NME8 GPX2 GPX2 COX16 COX16 TXNDC2 TXNDC2 C1orf198 C1orf198 LOC105538427 LOC105538427 ENSMLEP00000014083 ENSMLEP00000014083 ENSMLEP00000013926 ENSMLEP00000013926 ENSMLEP00000013869 ENSMLEP00000013869 SURF1 SURF1 COX6B1 COX6B1 TXNRD1 TXNRD1 YWHAQ YWHAQ TXNDC8 TXNDC8 NDUFA4 NDUFA4 SCO1 SCO1 ENSMLEP00000010938 ENSMLEP00000010938 LOC105531657 LOC105531657 TXN TXN RHEB RHEB RRM2B RRM2B PRKAG3 PRKAG3 COX18 COX18 AGO3 AGO3 ENSMLEP00000007765 ENSMLEP00000007765 TXNDC11 TXNDC11 ENSMLEP00000006859 ENSMLEP00000006859 COX7B2 COX7B2 ENSMLEP00000006706 ENSMLEP00000006706 RRAGA RRAGA ENSMLEP00000005642 ENSMLEP00000005642 PRKAB1 PRKAB1 MTOR MTOR SESN1 SESN1 ENSMLEP00000005144 ENSMLEP00000005144 LOC105532385 LOC105532385 LAMTOR2 LAMTOR2 COX4I2 COX4I2 COX6A1 COX6A1 PRKAA2 PRKAA2 ENSMLEP00000003563 ENSMLEP00000003563 LOC105549520 LOC105549520 GPI GPI ENSMLEP00000002675 ENSMLEP00000002675 GSR GSR PRDX2 PRDX2 LOC105540906 LOC105540906 LOC105553485 LOC105553485 ENSMLEP00000001347 ENSMLEP00000001347 RRAGB RRAGB H6PD H6PD LOC105553918 LOC105553918 SESN3 SESN3 LOC105540905 LOC105540905 RRAGD RRAGD MOV10 MOV10 TP63 TP63 LOC105535203 LOC105535203 MT-CO3 MT-CO3 MT-CO2 MT-CO2 MT-CO1 MT-CO1
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
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gene fusions
gene co-occurrence
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LOC105533249Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (153 aa)
ENSMLEP00000040085Uncharacterized protein. (106 aa)
COX5ACytochrome c oxidase subunit 5A. (157 aa)
LRPPRCLeucine rich pentatricopeptide repeat containing. (1397 aa)
GLSGlutaminase. (491 aa)
COX8ACytochrome c oxidase subunit 8A. (69 aa)
DESI1Desumoylating isopeptidase 1. (168 aa)
RHEBL1RHEB like 1. (183 aa)
LOC105534886Uncharacterized protein. (72 aa)
ENSMLEP00000037960Uncharacterized protein. (153 aa)
GLS2Glutaminase 2. (602 aa)
PRDX1Peroxiredoxin 1. (199 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (402 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
LOC105533155Uncharacterized protein. (139 aa)
TXNRD3Thioredoxin reductase 3. (561 aa)
COX6B2Cytochrome c oxidase subunit 6B2. (63 aa)
LAMTOR5Late endosomal/lysosomal adaptor, MAPK and MTOR activator 5. (169 aa)
TNRC6BTrinucleotide repeat containing adaptor 6B. (1832 aa)
NME9NME/NM23 family member 9; Belongs to the NDK family. (330 aa)
LOC105537866CHCH domain-containing protein. (90 aa)
ENSMLEP00000034545Uncharacterized protein. (71 aa)
PRKAA1Non-specific serine/threonine protein kinase. (559 aa)
DDIT4DNA damage inducible transcript 4. (233 aa)
RRAGCRas related GTP binding C. (320 aa)
PRKAB2Protein kinase AMP-activated non-catalytic subunit beta 2. (272 aa)
LOC105538345Uncharacterized protein. (114 aa)
KIAA1671KIAA1671. (1758 aa)
G6PDGlucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (498 aa)
TIGARTP53 induced glycolysis regulatory phosphatase. (270 aa)
LOC105528871Uncharacterized protein. (115 aa)
PRKAG1Protein kinase AMP-activated non-catalytic subunit gamma 1. (326 aa)
COX6A2Cytochrome c oxidase subunit 6A, mitochondrial. (97 aa)
ENSMLEP00000032494Thioredoxin; Belongs to the thioredoxin family. (101 aa)
ENSMLEP00000032441Cytochrome c oxidase subunit; Belongs to the cytochrome c oxidase subunit 6B. (86 aa)
NPVFNeuropeptide VF precursor. (196 aa)
CRYBB3Uncharacterized protein; Belongs to the beta/gamma-crystallin family. (113 aa)
RPTORRegulatory associated protein of MTOR complex 1. (1291 aa)
GATCGlutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). Belongs to the GatC family. (136 aa)
YWHABTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta; Belongs to the 14-3-3 family. (246 aa)
AGO4Protein argonaute-4; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. (854 aa)
DESI2Desumoylating isopeptidase 2. (194 aa)
COX7BCytochrome c oxidase subunit 7B. (80 aa)
TSC2TSC complex subunit 2. (1807 aa)
MLST8MTOR associated protein, LST8 homolog. (335 aa)
AGO2Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] (888 aa)
ENSMLEP00000028979Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (99 aa)
COX11Cytochrome c oxidase copper chaperone COX11. (276 aa)
AGO1Argonaute RISC component 1; Belongs to the argonaute family. (857 aa)
LAMTOR4Late endosomal/lysosomal adaptor, MAPK and MTOR activator 4. (112 aa)
ENSMLEP00000028457Uncharacterized protein. (107 aa)
AKT1Non-specific serine/threonine protein kinase. (432 aa)
PRKAG2Protein kinase AMP-activated non-catalytic subunit gamma 2. (506 aa)
ENSMLEP00000027047Uncharacterized protein. (125 aa)
LAMTOR1Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1. (161 aa)
TACO1Translational activator of cytochrome c oxidase I. (297 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
TSC1TSC complex subunit 1. (1162 aa)
LOC10552817014_3_3 domain-containing protein; Belongs to the 14-3-3 family. (208 aa)
LOC105544325Thioredoxin; Belongs to the thioredoxin family. (101 aa)
PRDX5Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. (215 aa)
CRYGNCrystallin gamma N; Belongs to the beta/gamma-crystallin family. (182 aa)
SESN2Sestrin 2. (450 aa)
DDIT4LDNA damage inducible transcript 4 like. (193 aa)
YWHAHTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta; Belongs to the 14-3-3 family. (223 aa)
ENSMLEP00000022340Uncharacterized protein. (117 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
LAMTOR3Late endosomal/lysosomal adaptor, MAPK and MTOR activator 3. (124 aa)
COX6CCytochrome c oxidase subunit 6C. (75 aa)
SLC38A9Solute carrier family 38 member 9. (561 aa)
COX20Cytochrome c oxidase assembly factor COX20. (116 aa)
ENSMLEP00000019251Thioredoxin domain-containing protein. (192 aa)
YWHAETyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon; Belongs to the 14-3-3 family. (255 aa)
YWHAZ14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (245 aa)
ENSMLEP0000001770314_3_3 domain-containing protein; Belongs to the 14-3-3 family. (255 aa)
NME8NME/NM23 family member 8. (588 aa)
GPX2Glutathione peroxidase; Belongs to the glutathione peroxidase family. (150 aa)
COX16Cytochrome c oxidase assembly factor COX16. (106 aa)
TXNDC2Thioredoxin domain containing 2. (448 aa)
C1orf198Chromosome 1 open reading frame 198. (327 aa)
LOC105538427Uncharacterized protein. (138 aa)
ENSMLEP00000014083Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (86 aa)
ENSMLEP00000013926Uncharacterized protein. (138 aa)
ENSMLEP0000001386914_3_3 domain-containing protein; Belongs to the 14-3-3 family. (214 aa)
SURF1SURF1-like protein; Component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex, that regulates cytochrome c oxidase assembly. Belongs to the SURF1 family. (300 aa)
COX6B1Cytochrome c oxidase subunit; Belongs to the cytochrome c oxidase subunit 6B. (87 aa)
TXNRD1Thioredoxin reductase 1. (647 aa)
YWHAQ14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (248 aa)
TXNDC8Thioredoxin domain containing 8. (127 aa)
NDUFA4NDUFA4 mitochondrial complex associated. (81 aa)
SCO1SCO cytochrome c oxidase assembly protein 1. (303 aa)
ENSMLEP0000001093814_3_3 domain-containing protein. (68 aa)
LOC105531657Uncharacterized protein. (129 aa)
TXNThioredoxin domain-containing protein. (83 aa)
RHEBRas homolog, mTORC1 binding. (181 aa)
RRM2BRibonucleotide reductase regulatory TP53 inducible subunit M2B. (352 aa)
PRKAG3Protein kinase AMP-activated non-catalytic subunit gamma 3. (489 aa)
COX18Cytochrome c oxidase assembly factor COX18. (333 aa)
AGO3Protein argonaute-3; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. (860 aa)
ENSMLEP00000007765Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
TXNDC11Thioredoxin domain containing 11. (919 aa)
ENSMLEP0000000685914_3_3 domain-containing protein; Belongs to the 14-3-3 family. (196 aa)
COX7B2Cytochrome c oxidase subunit 7B2. (81 aa)
ENSMLEP00000006706Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (96 aa)
RRAGARas related GTP binding A. (313 aa)
ENSMLEP00000005642Uncharacterized protein. (57 aa)
PRKAB1Protein kinase AMP-activated non-catalytic subunit beta 1. (270 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa)
SESN1Sestrin 1. (551 aa)
ENSMLEP00000005144Thioredoxin; Belongs to the thioredoxin family. (105 aa)
LOC105532385Cytochrome c oxidase subunit 6A, mitochondrial. (98 aa)
LAMTOR2Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2. (177 aa)
COX4I2Cytochrome c oxidase subunit 4I2. (171 aa)
COX6A1Cytochrome c oxidase subunit 6A, mitochondrial. (109 aa)
PRKAA2Non-specific serine/threonine protein kinase. (542 aa)
ENSMLEP00000003563Uncharacterized protein. (63 aa)
LOC105549520Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa)
GPIGlucose-6-phosphate isomerase; Belongs to the GPI family. (564 aa)
ENSMLEP00000002675Uncharacterized protein. (63 aa)
GSRGlutathione-disulfide reductase. (448 aa)
PRDX2Peroxiredoxin 2. (198 aa)
LOC10554090614-3-3 protein sigma. (248 aa)
LOC105553485Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
ENSMLEP00000001347Uncharacterized protein. (63 aa)
RRAGBRas related GTP binding B. (374 aa)
H6PDHexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase. (802 aa)
LOC105553918Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
SESN3Sestrin 3. (530 aa)
LOC10554090514_3_3 domain-containing protein; Belongs to the 14-3-3 family. (248 aa)
RRAGDRas related GTP binding D. (400 aa)
MOV10Mov10 RISC complex RNA helicase. (1003 aa)
TP63Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (595 aa)
LOC105535203Uncharacterized protein. (63 aa)
MT-CO3Cytochrome c oxidase subunit 3; Subunits I, II and III form the functional core of the enzyme complex. (261 aa)
MT-CO2Cytochrome c oxidase subunit 2; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...] (227 aa)
MT-CO1Cytochrome c oxidase subunit 1; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B. (522 aa)
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
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