STRINGSTRING
RPS27A RPS27A RBFOX2 RBFOX2 FGF1 FGF1 LOC105549607 LOC105549607 POLR2E POLR2E ENSMLEP00000002991 ENSMLEP00000002991 GTF2F2 GTF2F2 PTBP1 PTBP1 ESRP1 ESRP1 LOC105541098 LOC105541098 HNRNPF HNRNPF ENSMLEP00000006240 ENSMLEP00000006240 PTPN11 PTPN11 FGF23 FGF23 ERAS ERAS FGFR2 FGFR2 GTF2F1 GTF2F1 LOC105536598 LOC105536598 FGF20 FGF20 KRAS KRAS FGF10 FGF10 FGF9 FGF9 PPP2R1A PPP2R1A ENSMLEP00000011184 ENSMLEP00000011184 FGF18 FGF18 ENSMLEP00000011388 ENSMLEP00000011388 ENSMLEP00000012128 ENSMLEP00000012128 ENSMLEP00000012301 ENSMLEP00000012301 NCBP1 NCBP1 POLR2A POLR2A ENSMLEP00000013226 ENSMLEP00000013226 PPP2CA PPP2CA PTBP2 PTBP2 FNDC3B FNDC3B POLR2C POLR2C GAB1 GAB1 FNDC3A FNDC3A POLR2G POLR2G GRB2 GRB2 POLR2F POLR2F FGF2 FGF2 POLR2J POLR2J FGF5 FGF5 FGF16 FGF16 PIK3CA PIK3CA MKNK2 MKNK2 TIAL1 TIAL1 MAPK3 MAPK3 PPP2CB PPP2CB SOS1 SOS1 FGF3 FGF3 POLR2D POLR2D MAPK1 MAPK1 FGF6 FGF6 CBL CBL PTBP3 PTBP3 ENSMLEP00000027485 ENSMLEP00000027485 POLR2K POLR2K ENSMLEP00000028290 ENSMLEP00000028290 PLCG1 PLCG1 UBA52 UBA52 CSDE1 CSDE1 FGF8 FGF8 POLR2B POLR2B NRAS NRAS POLR2I POLR2I LOC105554897 LOC105554897 POLR2H POLR2H FRS2 FRS2 SPRY2 SPRY2 NCBP2 NCBP2 LOC105531220 LOC105531220 ENSMLEP00000032493 ENSMLEP00000032493 FRS3 FRS3 FGF7 FGF7 PIK3R1 PIK3R1 ENSMLEP00000034242 ENSMLEP00000034242 BRAF BRAF ENSMLEP00000035415 ENSMLEP00000035415 SRC SRC ENSMLEP00000035771 ENSMLEP00000035771 SHC1 SHC1 HRAS HRAS HNRNPM HNRNPM MKNK1 MKNK1 FGF17 FGF17 ESRP2 ESRP2 HNRNPA1 HNRNPA1 TIA1 TIA1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RPS27AUbiquitin-like domain-containing protein. (138 aa)
RBFOX2RNA binding protein fox-1 homolog 2; RNA-binding protein that regulates alternative splicing events. (389 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
LOC105549607Uncharacterized protein. (482 aa)
POLR2ERNA polymerase II subunit E. (176 aa)
ENSMLEP00000002991Uncharacterized protein. (68 aa)
GTF2F2General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (249 aa)
PTBP1Polypyrimidine tract binding protein 1. (607 aa)
ESRP1Epithelial splicing regulatory protein 1. (681 aa)
LOC105541098Ubiquitin-like domain-containing protein. (156 aa)
HNRNPFHeterogeneous nuclear ribonucleoprotein F. (415 aa)
ENSMLEP00000006240Ubiquitin-like domain-containing protein. (127 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (656 aa)
FGF23Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (251 aa)
ERASES cell expressed Ras. (233 aa)
FGFR2Fibroblast growth factor receptor. (838 aa)
GTF2F1Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (545 aa)
LOC105536598Ubiquitin-like domain-containing protein. (156 aa)
FGF20Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
PPP2R1AProtein phosphatase 2 scaffold subunit Aalpha. (589 aa)
ENSMLEP00000011184Uncharacterized protein. (308 aa)
FGF18Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (288 aa)
ENSMLEP00000011388Ubiquitin-like domain-containing protein. (120 aa)
ENSMLEP00000012128Uncharacterized protein. (234 aa)
ENSMLEP00000012301Protein kinase domain-containing protein. (294 aa)
NCBP1Nuclear cap binding protein subunit 1. (790 aa)
POLR2ADNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1936 aa)
ENSMLEP00000013226RRM domain-containing protein. (256 aa)
PPP2CASerine/threonine-protein phosphatase. (275 aa)
PTBP2Polypyrimidine tract binding protein 2. (537 aa)
FNDC3BFibronectin type III domain containing 3B. (1206 aa)
POLR2CRNA polymerase II subunit C. (275 aa)
GAB1GRB2 associated binding protein 1. (724 aa)
FNDC3AFibronectin type III domain containing 3A. (1198 aa)
POLR2GRNA polymerase II subunit G. (172 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
POLR2FRNA polymerase II subunit F. (158 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
POLR2JRNA_pol_L_2 domain-containing protein. (159 aa)
FGF5Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (268 aa)
FGF16Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
MKNK2MAPK interacting serine/threonine kinase 2; Belongs to the protein kinase superfamily. (383 aa)
TIAL1TIA1 cytotoxic granule associated RNA binding protein like 1. (396 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (364 aa)
PPP2CBSerine/threonine-protein phosphatase. (275 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1299 aa)
FGF3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa)
POLR2DRNA polymerase II subunit D. (142 aa)
MAPK1Mitogen-activated protein kinase. (343 aa)
FGF6Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
CBLCbl proto-oncogene. (881 aa)
PTBP3Polypyrimidine tract binding protein 3. (558 aa)
ENSMLEP00000027485PID domain-containing protein. (488 aa)
POLR2KRNA polymerase II subunit K. (58 aa)
ENSMLEP00000028290Uncharacterized protein. (441 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1276 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
CSDE1Cold shock domain containing E1. (844 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (239 aa)
POLR2BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1167 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
POLR2IDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (125 aa)
LOC105554897Uncharacterized protein. (305 aa)
POLR2HDNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (150 aa)
FRS2Fibroblast growth factor receptor substrate 2. (522 aa)
SPRY2Sprouty RTK signaling antagonist 2. (338 aa)
NCBP2Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (89 aa)
LOC105531220RRM domain-containing protein. (264 aa)
ENSMLEP00000032493RRM domain-containing protein. (350 aa)
FRS3Fibroblast growth factor receptor substrate 3. (492 aa)
FGF7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
ENSMLEP00000034242Uncharacterized protein. (173 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (745 aa)
ENSMLEP00000035415Uncharacterized protein. (519 aa)
SRCTyrosine-protein kinase. (542 aa)
ENSMLEP00000035771Uncharacterized protein. (68 aa)
SHC1SHC adaptor protein 1. (584 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
HNRNPMHeterogeneous nuclear ribonucleoprotein M. (730 aa)
MKNK1MAPK interacting serine/threonine kinase 1; Belongs to the protein kinase superfamily. (465 aa)
FGF17Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa)
ESRP2Epithelial splicing regulatory protein 2. (618 aa)
HNRNPA1Heterogeneous nuclear ribonucleoprotein A1. (372 aa)
TIA1TIA1 cytotoxic granule associated RNA binding protein. (386 aa)
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
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