STRINGSTRING
GTF2H5 GTF2H5 ATAD5 ATAD5 COPS2 COPS2 ENSMLEP00000000876 ENSMLEP00000000876 RPS27A RPS27A WDR76 WDR76 UBE2NL UBE2NL PCNA PCNA PARP1 PARP1 LIG3 LIG3 ENSMLEP00000003269 ENSMLEP00000003269 WBP1 WBP1 COPS5 COPS5 LOC105541098 LOC105541098 LOC105534329 LOC105534329 ENSMLEP00000005277 ENSMLEP00000005277 CETN3 CETN3 ENSMLEP00000005424 ENSMLEP00000005424 LIG1 LIG1 LOC105552923 LOC105552923 RAD23A RAD23A ENSMLEP00000006240 ENSMLEP00000006240 LOC105537674 LOC105537674 ENSMLEP00000006951 ENSMLEP00000006951 VWA5B2 VWA5B2 BIVM BIVM INO80E INO80E LOC105536598 LOC105536598 LOC105553920 LOC105553920 RAD23B RAD23B LOC105554521 LOC105554521 CUL4B CUL4B ENSMLEP00000010931 ENSMLEP00000010931 ERCC1 ERCC1 LOC105543372 LOC105543372 ENSMLEP00000011388 ENSMLEP00000011388 POLE4 POLE4 RFC5 RFC5 RCBTB1 RCBTB1 ENSMLEP00000013375 ENSMLEP00000013375 CHD1L CHD1L USP45 USP45 TFPT TFPT CCNH CCNH VTCN1 VTCN1 ENSMLEP00000014667 ENSMLEP00000014667 VWA5A VWA5A ENSMLEP00000015845 ENSMLEP00000015845 ENSMLEP00000015948 ENSMLEP00000015948 DDB2 DDB2 SUMO2 SUMO2 CUL4A CUL4A PARP2 PARP2 POLE3 POLE3 RFC4 RFC4 INO80C INO80C ENSMLEP00000018394 ENSMLEP00000018394 UBE2V2 UBE2V2 LOC105548148 LOC105548148 CDK7 CDK7 GPS1 GPS1 RFC3 RFC3 YY1 YY1 ACTL6A ACTL6A RCBTB2 RCBTB2 SUMO1 SUMO1 COPS4 COPS4 PARP3 PARP3 MNAT1 MNAT1 ENSMLEP00000022706 ENSMLEP00000022706 MEIOB MEIOB RPAP3 RPAP3 POLD3 POLD3 ENSMLEP00000024034 ENSMLEP00000024034 RPA3 RPA3 COPS8 COPS8 RFC2 RFC2 ENSMLEP00000024489 ENSMLEP00000024489 ENSMLEP00000024890 ENSMLEP00000024890 CETN2 CETN2 NFRKB NFRKB COPS7A COPS7A UBE2I UBE2I VWA5B1 VWA5B1 GTF2H3 GTF2H3 POLD1 POLD1 COPS3 COPS3 ACTR5 ACTR5 RUVBL1 RUVBL1 RPA1 RPA1 UBA52 UBA52 ACTB ACTB LOC105541173 LOC105541173 ENSMLEP00000030622 ENSMLEP00000030622 ENSMLEP00000030942 ENSMLEP00000030942 INO80D INO80D XRCC1 XRCC1 POLD4 POLD4 POLD2 POLD2 COPS7B COPS7B MCRS1 MCRS1 ENSMLEP00000033961 ENSMLEP00000033961 ACTR8 ACTR8 ENSMLEP00000034242 ENSMLEP00000034242 SUMO3 SUMO3 INO80B INO80B XPC XPC POLE POLE ERCC3 ERCC3 INO80 INO80 LOC105538134 LOC105538134 GTF2H1 GTF2H1 PIAS1 PIAS1 LOC105541671 LOC105541671 ENSMLEP00000037330 ENSMLEP00000037330 POLK POLK PIAS3 PIAS3 GTF2H4 GTF2H4 KCTD2 KCTD2 NFATC2IP NFATC2IP ERCC4 ERCC4 ERCC2 ERCC2 COPS6 COPS6 XPA XPA RNF111 RNF111 DDB1 DDB1 RBX1 RBX1 RFC1 RFC1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GTF2H5General transcription factor IIH subunit 5. (71 aa)
ATAD5ATPase family AAA domain containing 5. (1834 aa)
COPS2COP9 signalosome subunit 2. (450 aa)
ENSMLEP00000000876Ubiquitin-like domain-containing protein. (132 aa)
RPS27AUbiquitin-like domain-containing protein. (138 aa)
WDR76WD repeat-containing protein 76; Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC. Belongs to the WD repeat DDB2/WDR76 family. (598 aa)
UBE2NLUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (89 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
PARP1Poly [ADP-ribose] polymerase. (1017 aa)
LIG3DNA ligase. (1009 aa)
ENSMLEP00000003269MPN domain-containing protein. (334 aa)
WBP1WW domain binding protein 1. (302 aa)
COPS5MPN domain-containing protein. (334 aa)
LOC105541098Ubiquitin-like domain-containing protein. (156 aa)
LOC105534329UBIQUITIN_CONJUGAT_2 domain-containing protein. (145 aa)
ENSMLEP00000005277Small ubiquitin-related modifier. (103 aa)
CETN3Centrin 3. (191 aa)
ENSMLEP00000005424UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (142 aa)
LIG1DNA ligase. (918 aa)
LOC105552923Small ubiquitin-related modifier. (95 aa)
RAD23ARAD23 homolog A, nucleotide excision repair protein. (363 aa)
ENSMLEP00000006240Ubiquitin-like domain-containing protein. (127 aa)
LOC105537674UBIQUITIN_CONJUGAT_2 domain-containing protein. (145 aa)
ENSMLEP00000006951Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (268 aa)
VWA5B2Von Willebrand factor A domain containing 5B2. (1243 aa)
BIVMBIVM-ERCC5 readthrough. (1638 aa)
INO80EINO80 complex subunit E. (227 aa)
LOC105536598Ubiquitin-like domain-containing protein. (156 aa)
LOC105553920BSD domain-containing protein. (430 aa)
RAD23BRAD23 homolog B, nucleotide excision repair protein. (392 aa)
LOC105554521DNA_pol_E_B domain-containing protein. (252 aa)
CUL4BCullin 4B; Belongs to the cullin family. (931 aa)
ENSMLEP00000010931Uncharacterized protein. (79 aa)
ERCC1ERCC excision repair 1, endonuclease non-catalytic subunit. (323 aa)
LOC105543372General transcription factor IIH subunit. (380 aa)
ENSMLEP00000011388Ubiquitin-like domain-containing protein. (120 aa)
POLE4DNA polymerase epsilon 4, accessory subunit. (119 aa)
RFC5Replication factor C subunit 5. (340 aa)
RCBTB1RCC1 and BTB domain containing protein 1. (531 aa)
ENSMLEP00000013375Small ubiquitin-related modifier. (100 aa)
CHD1LChromodomain helicase DNA binding protein 1 like. (900 aa)
USP45Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (815 aa)
TFPTTCF3 fusion partner. (253 aa)
CCNHCyclin H; Belongs to the cyclin family. (325 aa)
VTCN1V-set domain containing T cell activation inhibitor 1. (285 aa)
ENSMLEP00000014667Uncharacterized protein. (140 aa)
VWA5AVon Willebrand factor A domain containing 5A. (786 aa)
ENSMLEP00000015845Rad60-SLD domain-containing protein. (78 aa)
ENSMLEP00000015948Uncharacterized protein. (90 aa)
DDB2Damage specific DNA binding protein 2. (427 aa)
SUMO2Rad60-SLD domain-containing protein. (70 aa)
CUL4ACullin 4A; Belongs to the cullin family. (587 aa)
PARP2Poly [ADP-ribose] polymerase. (583 aa)
POLE3DNA polymerase epsilon 3, accessory subunit. (147 aa)
RFC4Replication factor C subunit 4. (363 aa)
INO80CYL1_C domain-containing protein. (228 aa)
ENSMLEP00000018394UBIQUITIN_CONJUGAT_2 domain-containing protein. (129 aa)
UBE2V2Ubiquitin conjugating enzyme E2 V2. (155 aa)
LOC105548148Protein kinase domain-containing protein. (312 aa)
CDK7Cyclin dependent kinase 7; Belongs to the protein kinase superfamily. (346 aa)
GPS1G protein pathway suppressor 1. (483 aa)
RFC3Replication factor C subunit 3. (356 aa)
YY1Uncharacterized protein. (189 aa)
ACTL6AActin like 6A; Belongs to the actin family. (430 aa)
RCBTB2RCC1 and BTB domain containing protein 2. (556 aa)
SUMO1Ubiquitin-like domain-containing protein. (62 aa)
COPS4COP9 signalosome subunit 4. (426 aa)
PARP3Poly [ADP-ribose] polymerase. (531 aa)
MNAT1MNAT1 component of CDK activating kinase. (234 aa)
ENSMLEP00000022706Zf-rbx1 domain-containing protein. (93 aa)
MEIOBMeiosis specific with OB-fold. (407 aa)
RPAP3RNA polymerase II associated protein 3. (665 aa)
POLD3Uncharacterized protein. (454 aa)
ENSMLEP00000024034UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (142 aa)
RPA3Replication protein A3. (121 aa)
COPS8COP9 signalosome subunit 8. (209 aa)
RFC2Replication factor C subunit 2. (352 aa)
ENSMLEP00000024489Ubiquitin-like domain-containing protein. (115 aa)
ENSMLEP00000024890Uncharacterized protein. (54 aa)
CETN2Centrin 2. (172 aa)
NFRKBNuclear factor related to kappaB binding protein. (1324 aa)
COPS7ACOP9 signalosome subunit 7A. (275 aa)
UBE2IUbiquitin conjugating enzyme E2 I; Belongs to the ubiquitin-conjugating enzyme family. (194 aa)
VWA5B1Von Willebrand factor A domain containing 5B1. (1190 aa)
GTF2H3General transcription factor IIH subunit 3. (308 aa)
POLD1DNA polymerase. (1134 aa)
COPS3COP9 signalosome subunit 3. (394 aa)
ACTR5Actin related protein 5; Belongs to the actin family. (532 aa)
RUVBL1RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (595 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
ACTBActin beta. (375 aa)
LOC105541173MPN domain-containing protein. (322 aa)
ENSMLEP00000030622Small ubiquitin-related modifier. (81 aa)
ENSMLEP00000030942Dpoe2NT domain-containing protein. (96 aa)
INO80DINO80 complex subunit D. (1027 aa)
XRCC1X-ray repair cross complementing 1. (645 aa)
POLD4Uncharacterized protein. (107 aa)
POLD2DNA polymerase delta 2, accessory subunit. (504 aa)
COPS7BCOP9 signalosome subunit 7B. (273 aa)
MCRS1Microspherule protein 1. (475 aa)
ENSMLEP00000033961Uncharacterized protein. (78 aa)
ACTR8Actin-related protein 8; Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize; Belongs to the actin family. ARP8 subfamily. (624 aa)
ENSMLEP00000034242Uncharacterized protein. (173 aa)
SUMO3Ubiquitin-like domain-containing protein. (189 aa)
INO80BPAPA-1 domain-containing protein. (356 aa)
XPCXPC complex subunit, DNA damage recognition and repair factor. (939 aa)
POLEDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2288 aa)
ERCC3ERCC excision repair 3, TFIIH core complex helicase subunit. (782 aa)
INO80INO80 complex ATPase subunit. (1556 aa)
LOC105538134Ubiquitin-like domain-containing protein. (342 aa)
GTF2H1General transcription factor IIH subunit 1. (548 aa)
PIAS1Protein inhibitor of activated STAT 1. (653 aa)
LOC105541671Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (252 aa)
ENSMLEP00000037330Small ubiquitin-related modifier. (103 aa)
POLKDNA polymerase kappa. (870 aa)
PIAS3Protein inhibitor of activated STAT 3. (634 aa)
GTF2H4General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (462 aa)
KCTD2Uncharacterized protein. (64 aa)
NFATC2IPNuclear factor of activated T cells 2 interacting protein. (419 aa)
ERCC4ERCC excision repair 4, endonuclease catalytic subunit. (916 aa)
ERCC2ERCC excision repair 2, TFIIH core complex helicase subunit. (760 aa)
COPS6MPN domain-containing protein. (332 aa)
XPAXPA, DNA damage recognition and repair factor. (273 aa)
RNF111Ring finger protein 111. (994 aa)
DDB1Damage specific DNA binding protein 1. (1147 aa)
RBX1RING-type domain-containing protein. (108 aa)
RFC1Replication factor C subunit 1. (1148 aa)
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
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