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| | PSMD3 | Proteasome 26S subunit, non-ATPase 3. (534 aa) |
| | CUL1 | Cullin 1; Belongs to the cullin family. (776 aa) |
| | ENSMLEP00000040613 | Protein kinase domain-containing protein. (286 aa) |
| | PSMD6 | Proteasome 26S subunit, non-ATPase 6. (442 aa) |
| | LIN37 | Lin-37 DREAM MuvB core complex component. (246 aa) |
| | PSMD14 | Proteasome 26S subunit, non-ATPase 14. (315 aa) |
| | ENSMLEP00000038668 | Prot_ATP_ID_OB domain-containing protein. (166 aa) |
| | MCM6 | DNA helicase; Belongs to the MCM family. (821 aa) |
| | PPP2R1B | Protein phosphatase 2 scaffold subunit Abeta. (637 aa) |
| | CDK1 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (297 aa) |
| | HDAC1 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (482 aa) |
| | ENSMLEP00000038171 | Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (66 aa) |
| | ENSMLEP00000038111 | Proteasome endopeptidase complex. (222 aa) |
| | PSMD7 | Proteasome 26S subunit, non-ATPase 7. (324 aa) |
| | PSMB5 | Proteasome subunit beta. (263 aa) |
| | MCM5 | DNA helicase; Belongs to the MCM family. (734 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | LOC105541671 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (252 aa) |
| | MAX | MYC associated factor X. (160 aa) |
| | POLE | DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2288 aa) |
| | LOC105548097 | WD_REPEATS_REGION domain-containing protein. (401 aa) |
| | PSMA3 | Proteasome subunit alpha type. (255 aa) |
| | MCM3 | DNA helicase; Belongs to the MCM family. (853 aa) |
| | CDC25A | Cell division cycle 25A. (524 aa) |
| | CDT1 | Chromatin licensing and DNA replication factor 1. (470 aa) |
| | FNBP4 | Formin binding protein 4. (1017 aa) |
| | PSME2 | Proteasome activator subunit 2. (239 aa) |
| | CCNA2 | Cyclin A2; Belongs to the cyclin family. (432 aa) |
| | ENSMLEP00000034242 | Uncharacterized protein. (173 aa) |
| | PSMB2 | Proteasome subunit beta. (201 aa) |
| | ORC4 | Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (436 aa) |
| | GMNN | Geminin DNA replication inhibitor. (209 aa) |
| | CDC45 | Cell division cycle 45. (598 aa) |
| | ENSMLEP00000033047 | Uncharacterized protein. (67 aa) |
| | CREBZF | CREB/ATF bZIP transcription factor. (358 aa) |
| | PSMC2 | Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (467 aa) |
| | ORC2 | Origin recognition complex subunit 2. (577 aa) |
| | ENSMLEP00000031844 | Uncharacterized protein. (347 aa) |
| | PSMB10 | Proteasome subunit beta. (273 aa) |
| | PSMC6 | AAA domain-containing protein; Belongs to the AAA ATPase family. (403 aa) |
| | PRIM2 | DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. (509 aa) |
| | ENSMLEP00000030942 | Dpoe2NT domain-containing protein. (96 aa) |
| | CCNE1 | Cyclin E1; Belongs to the cyclin family. (407 aa) |
| | RBBP4 | WD_REPEATS_REGION domain-containing protein. (432 aa) |
| | ORC1 | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (861 aa) |
| | UBA52 | Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa) |
| | POLA2 | Uncharacterized protein. (548 aa) |
| | RPA1 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (595 aa) |
| | PSMA6 | Proteasome subunit alpha type. (252 aa) |
| | LOC105538326 | WRNPLPNID domain-containing protein. (953 aa) |
| | RBL2 | RB transcriptional corepressor like 2. (1139 aa) |
| | LIN54 | Lin-54 DREAM MuvB core complex component. (749 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase. (432 aa) |
| | CCNA1 | Cyclin A1; Belongs to the cyclin family. (465 aa) |
| | MCM2 | DNA helicase; Belongs to the MCM family. (757 aa) |
| | PSMC4 | Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa) |
| | POLA1 | DNA polymerase. (1420 aa) |
| | LOC105529488 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (458 aa) |
| | PSMC1 | Proteasome 26S subunit, ATPase 1; Belongs to the AAA ATPase family. (440 aa) |
| | MCM10 | Minichromosome maintenance 10 replication initiation factor. (822 aa) |
| | ENSMLEP00000026600 | Uncharacterized protein. (360 aa) |
| | PSME1 | Proteasome activator subunit 1. (284 aa) |
| | CDK4 | Cyclin dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa) |
| | ENSMLEP00000025412 | Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (69 aa) |
| | ENSMLEP00000025123 | CSN8_PSD8_EIF3K domain-containing protein. (254 aa) |
| | E2F4 | E2F transcription factor 4. (416 aa) |
| | PSMD8 | Proteasome 26S subunit, non-ATPase 8. (350 aa) |
| | LOC105541595 | RPA_C domain-containing protein. (250 aa) |
| | RPA3 | Replication protein A3. (121 aa) |
| | SKP2 | S-phase kinase associated protein 2. (424 aa) |
| | CDC7 | Protein kinase domain-containing protein. (574 aa) |
| | ENSMLEP00000023964 | Uncharacterized protein. (190 aa) |
| | PSMD2 | 26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (888 aa) |
| | PSMD1 | 26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa) |
| | CKS2 | Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa) |
| | MEIOB | Meiosis specific with OB-fold. (407 aa) |
| | E2F5 | E2F transcription factor 5. (312 aa) |
| | RRM2 | Ribonucleotide reductase regulatory subunit M2. (407 aa) |
| | RELCH | RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing. (1195 aa) |
| | MNAT1 | MNAT1 component of CDK activating kinase. (234 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) |
| | LOC105536463 | AAA domain-containing protein; Belongs to the AAA ATPase family. (366 aa) |
| | RPS27A | Ubiquitin-like domain-containing protein. (138 aa) |
| | ENSMLEP00000000931 | MPN domain-containing protein. (299 aa) |
| | CDK2 | Cyclin dependent kinase 2; Belongs to the protein kinase superfamily. (346 aa) |
| | E2F1 | E2F transcription factor 1. (381 aa) |
| | MCM8 | MCM domain-containing protein; Belongs to the MCM family. (880 aa) |
| | PSMD13 | Proteasome 26S subunit, non-ATPase 13. (351 aa) |
| | PRIM1 | DNA primase; Belongs to the eukaryotic-type primase small subunit family. (420 aa) |
| | PSMB9 | Proteasome subunit beta. (196 aa) |
| | PSME3 | Proteasome activator subunit 3. (267 aa) |
| | PCNA | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa) |
| | CDC6 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (559 aa) |
| | PSMA4 | Proteasome subunit alpha type. (261 aa) |
| | PSMB4 | Proteasome subunit beta; Belongs to the peptidase T1B family. (274 aa) |
| | LOC105541098 | Ubiquitin-like domain-containing protein. (156 aa) |
| | PSMB6 | Proteasome subunit beta. (242 aa) |
| | WEE2 | Wee1-like protein kinase. (568 aa) |
| | PSMC5 | Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa) |
| | ENSMLEP00000005586 | ATPase_AAA_core domain-containing protein; Belongs to the AAA ATPase family. (179 aa) |
| | PSMB3 | Proteasome subunit beta. (205 aa) |
| | ENSMLEP00000006240 | Ubiquitin-like domain-containing protein. (127 aa) |
| | ENSMLEP00000006413 | AAA domain-containing protein; Belongs to the AAA ATPase family. (423 aa) |
| | DBF4 | DBF4 zinc finger. (674 aa) |
| | ENSMLEP00000006951 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (268 aa) |
| | CDK3 | Cyclin dependent kinase 3; Belongs to the protein kinase superfamily. (305 aa) |
| | SKP1 | S-phase kinase associated protein 1; Belongs to the SKP1 family. (165 aa) |
| | LOC105536598 | Ubiquitin-like domain-containing protein. (156 aa) |
| | ENSMLEP00000008311 | Uncharacterized protein; Belongs to the SKP1 family. (142 aa) |
| | PPP4R4 | Protein phosphatase 4 regulatory subunit 4. (843 aa) |
| | PSMB1 | Proteasome subunit beta. (241 aa) |
| | RBL1 | RB transcriptional corepressor like 1. (1038 aa) |
| | PSMB8 | Proteasome subunit beta. (276 aa) |
| | CCNB1 | Cyclin B1; Belongs to the cyclin family. (433 aa) |
| | PSMD9 | PDZ domain-containing protein. (223 aa) |
| | PTK6 | Tyrosine-protein kinase. (451 aa) |
| | ENSMLEP00000010500 | WD_REPEATS_REGION domain-containing protein. (410 aa) |
| | LOC105554521 | DNA_pol_E_B domain-containing protein. (252 aa) |
| | CDKN1B | Cyclin dependent kinase inhibitor 1B. (198 aa) |
| | PPP2R3A | Protein phosphatase 2 regulatory subunit B''alpha. (1150 aa) |
| | ENSMLEP00000010931 | Uncharacterized protein. (79 aa) |
| | MCM7 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (719 aa) |
| | PPP2R1A | Protein phosphatase 2 scaffold subunit Aalpha. (589 aa) |
| | ENSMLEP00000011388 | Ubiquitin-like domain-containing protein. (120 aa) |
| | POLE4 | DNA polymerase epsilon 4, accessory subunit. (119 aa) |
| | CDKN1A | Cyclin dependent kinase inhibitor 1A. (164 aa) |
| | KIAA2012 | KIAA2012. (1180 aa) |
| | LIN9 | Lin-9 DREAM MuvB core complex component. (615 aa) |
| | CKS1B | Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa) |
| | TFDP1 | Transcription factor. (410 aa) |
| | PSMD5 | Proteasome 26S subunit, non-ATPase 5. (508 aa) |
| | PSMA1 | Proteasome subunit alpha type. (269 aa) |
| | MCM9 | Minichromosome maintenance 9 homologous recombination repair factor; Belongs to the MCM family. (1141 aa) |
| | PPP4R1 | Protein phosphatase 4 regulatory subunit 1. (919 aa) |
| | PSMA2 | Proteasome subunit alpha type. (234 aa) |
| | MCM4 | DNA helicase; Belongs to the MCM family. (863 aa) |
| | CCNH | Cyclin H; Belongs to the cyclin family. (325 aa) |
| | E2F6 | E2F transcription factor 6. (281 aa) |
| | CCNE2 | Cyclin E2; Belongs to the cyclin family. (404 aa) |
| | FBXO5 | F-box protein 5. (448 aa) |
| | ORC3 | Origin recognition complex subunit 3. (646 aa) |
| | PPP2CA | Serine/threonine-protein phosphatase. (275 aa) |
| | CABLES1 | Cdk5 and Abl enzyme substrate 1. (363 aa) |
| | RPA2 | Replication protein A2. (356 aa) |
| | LIN52 | Lin-52 DREAM MuvB core complex component. (102 aa) |
| | TM4SF19 | Uncharacterized protein. (209 aa) |
| | PSMD10 | Proteasome 26S subunit, non-ATPase 10. (226 aa) |
| | ENSMLEP00000016378 | AAA domain-containing protein. (201 aa) |
| | ENSMLEP00000016498 | Transcription factor. (393 aa) |
| | ENSMLEP00000016528 | Uncharacterized protein. (191 aa) |
| | ENSMLEP00000016698 | AAA domain-containing protein; Belongs to the AAA ATPase family. (390 aa) |
| | LOC105555268 | Protein kinase domain-containing protein. (542 aa) |
| | ENSMLEP00000017044 | Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (86 aa) |
| | PSMD4 | Proteasome 26S subunit, non-ATPase 4. (378 aa) |
| | MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (454 aa) |
| | PSMC3 | AAA domain-containing protein; Belongs to the AAA ATPase family. (446 aa) |
| | TYMS | Thymidylate synthetase. (163 aa) |
| | POLE3 | DNA polymerase epsilon 3, accessory subunit. (147 aa) |
| | ENSMLEP00000018319 | WD_REPEATS_REGION domain-containing protein. (418 aa) |
| | LOC105545834 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (470 aa) |
| | LOC105548148 | Protein kinase domain-containing protein. (312 aa) |
| | CDK7 | Cyclin dependent kinase 7; Belongs to the protein kinase superfamily. (346 aa) |
| | ORC5 | Origin recognition complex subunit 5. (421 aa) |
| | PSMA5 | Proteasome subunit alpha type. (241 aa) |
| | ENSMLEP00000018790 | Uncharacterized protein. (416 aa) |
| | ORC6 | Origin recognition complex subunit 6. (203 aa) |
| | PSMA7 | Proteasome endopeptidase complex. (178 aa) |
| | PSMF1 | Proteasome inhibitor subunit 1. (271 aa) |
| | ENSMLEP00000019789 | ANK_REP_REGION domain-containing protein. (165 aa) |
| | PSMD11 | Proteasome 26S subunit, non-ATPase 11. (357 aa) |
| | PSMB7 | Proteasome subunit beta. (302 aa) |
| | ENSMLEP00000021044 | WD_REPEATS_REGION domain-containing protein. (259 aa) |
| | TK1 | Thymidine kinase. (275 aa) |
| | PSMD12 | Proteasome 26S subunit, non-ATPase 12. (456 aa) |
| | PPP2CB | Serine/threonine-protein phosphatase. (275 aa) |
| | RB1 | RB transcriptional corepressor 1. (891 aa) |
