STRINGSTRING
ENSMLEP00000000335 ENSMLEP00000000335 THOC3 THOC3 CPSF6 CPSF6 U2AF1L4 U2AF1L4 DDX39A DDX39A THOC6 THOC6 ZC3H11A ZC3H11A UPF3B UPF3B WDR25 WDR25 LOC105535221 LOC105535221 CSTF1 CSTF1 ENSMLEP00000004386 ENSMLEP00000004386 SNRPB SNRPB PCF11 PCF11 ENSMLEP00000005622 ENSMLEP00000005622 SLBP SLBP LSM10 LSM10 SRSF2 SRSF2 CPSF3 CPSF3 LSM11 LSM11 ENSMLEP00000008607 ENSMLEP00000008607 CASC3 CASC3 CPSF2 CPSF2 LOC105555555 LOC105555555 DHX38 DHX38 SRSF5 SRSF5 LUZP4 LUZP4 ENSMLEP00000011876 ENSMLEP00000011876 NCBP1 NCBP1 ENSMLEP00000013046 ENSMLEP00000013046 CPSF7 CPSF7 SNRPG SNRPG THOC5 THOC5 SRSF6 SRSF6 SRSF4 SRSF4 CHTOP CHTOP U2AF2 U2AF2 ENSMLEP00000016142 ENSMLEP00000016142 ENSMLEP00000016299 ENSMLEP00000016299 TPRG1 TPRG1 PAPOLA PAPOLA EIF4A3 EIF4A3 FYTTD1 FYTTD1 SNRPF SNRPF ENSMLEP00000020013 ENSMLEP00000020013 THOC1 THOC1 LOC105548167 LOC105548167 CPSF4 CPSF4 ENSMLEP00000021496 ENSMLEP00000021496 THOC2 THOC2 TPRG1L TPRG1L CDC40 CDC40 ENSMLEP00000024071 ENSMLEP00000024071 ENSMLEP00000024216 ENSMLEP00000024216 ZNF318 ZNF318 CSTF2 CSTF2 RNPS1 RNPS1 ENSMLEP00000025623 ENSMLEP00000025623 WDR33 WDR33 SNRPD3 SNRPD3 SLU7 SLU7 LOC105548633 LOC105548633 SRRM1 SRRM1 CPSF4L CPSF4L SARNP SARNP SRSF7 SRSF7 SREK1 SREK1 RBM8A RBM8A ZC3H13 ZC3H13 ENSMLEP00000030703 ENSMLEP00000030703 CSTF3 CSTF3 ENSMLEP00000031093 ENSMLEP00000031093 NCBP2 NCBP2 C12orf50 C12orf50 LOC105536165 LOC105536165 SRSF1 SRSF1 SYMPK SYMPK MAGOHB MAGOHB SRSF9 SRSF9 SRSF3 SRSF3 THOC7 THOC7 POLDIP3 POLDIP3 NUDT21 NUDT21 SRSF11 SRSF11 FIP1L1 FIP1L1 LOC105554415 LOC105554415 ZNF473 ZNF473 MAGOH MAGOH CPSF1 CPSF1 ALYREF ALYREF SNRPE SNRPE CLP1 CLP1 DDX39B DDX39B BCL2L2-PABPN1 BCL2L2-PABPN1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSMLEP00000000335Small nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (76 aa)
THOC3THO complex 3. (351 aa)
CPSF6Cleavage and polyadenylation specific factor 6. (568 aa)
U2AF1L4Uncharacterized protein. (220 aa)
DDX39ADExD-box helicase 39A. (435 aa)
THOC6THO complex 6. (341 aa)
ZC3H11AUncharacterized protein. (810 aa)
UPF3BUPF3B regulator of nonsense mediated mRNA decay. (483 aa)
WDR25WD repeat domain 25. (544 aa)
LOC105535221Uncharacterized protein. (248 aa)
CSTF1Cleavage stimulation factor subunit 1. (431 aa)
ENSMLEP00000004386Small nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. (85 aa)
SNRPBSmall nuclear ribonucleoprotein-associated protein. (240 aa)
PCF11PCF11 cleavage and polyadenylation factor subunit. (1555 aa)
ENSMLEP00000005622Small nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. (85 aa)
SLBPStem-loop binding protein. (257 aa)
LSM10LSM10, U7 small nuclear RNA associated. (123 aa)
SRSF2Serine and arginine rich splicing factor 2. (189 aa)
CPSF3Cleavage and polyadenylation specific factor 3. (684 aa)
LSM11LSM11, U7 small nuclear RNA associated. (210 aa)
ENSMLEP00000008607Small nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (70 aa)
CASC3CASC3 exon junction complex subunit. (634 aa)
CPSF2Cleavage and polyadenylation specificity factor subunit 2. (782 aa)
LOC105555555Uncharacterized protein. (237 aa)
DHX38DEAH-box helicase 38. (1234 aa)
SRSF5Serine and arginine rich splicing factor 5. (272 aa)
LUZP4Leucine zipper protein 4. (306 aa)
ENSMLEP00000011876Uncharacterized protein. (213 aa)
NCBP1Nuclear cap binding protein subunit 1. (790 aa)
ENSMLEP00000013046Small nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (74 aa)
CPSF7Cleavage and polyadenylation specific factor 7. (489 aa)
SNRPGSmall nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (96 aa)
THOC5THO complex 5. (683 aa)
SRSF6Serine and arginine rich splicing factor 6. (214 aa)
SRSF4Serine and arginine rich splicing factor 4. (494 aa)
CHTOPChromatin target of PRMT1. (277 aa)
U2AF2U2 snRNP auxiliary factor large subunit; Necessary for the splicing of pre-mRNA. Belongs to the splicing factor SR family. (512 aa)
ENSMLEP00000016142PWI domain-containing protein. (761 aa)
ENSMLEP00000016299Uncharacterized protein. (54 aa)
TPRG1Tumor protein p63 regulated 1. (279 aa)
PAPOLAPoly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's. (745 aa)
EIF4A3Eukaryotic translation initiation factor 4A3; Belongs to the DEAD box helicase family. (354 aa)
FYTTD1Forty-two-three domain containing 1. (286 aa)
SNRPFSm domain-containing protein. (127 aa)
ENSMLEP00000020013annotation not available (74 aa)
THOC1THO complex 1. (660 aa)
LOC105548167RRM domain-containing protein. (275 aa)
CPSF4Cleavage and polyadenylation specific factor 4. (269 aa)
ENSMLEP00000021496Uncharacterized protein. (136 aa)
THOC2THO complex 2. (1593 aa)
TPRG1LHSac2 domain-containing protein. (77 aa)
CDC40Cell division cycle 40. (579 aa)
ENSMLEP00000024071Sm domain-containing protein. (71 aa)
ENSMLEP00000024216Uncharacterized protein. (64 aa)
ZNF318Zinc finger protein 318. (2203 aa)
CSTF2Cleavage stimulation factor subunit 2. (597 aa)
RNPS1RNA binding protein with serine rich domain 1. (305 aa)
ENSMLEP00000025623Small nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. (90 aa)
WDR33WD repeat domain 33. (1336 aa)
SNRPD3Small nuclear ribonucleoprotein Sm D3; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing. (126 aa)
SLU7SLU7 homolog, splicing factor. (586 aa)
LOC105548633SAP domain-containing protein. (202 aa)
SRRM1PWI domain-containing protein. (898 aa)
CPSF4LCleavage and polyadenylation specific factor 4 like. (179 aa)
SARNPSAP domain-containing protein. (162 aa)
SRSF7Serine and arginine rich splicing factor 7. (238 aa)
SREK1Splicing regulatory glutamic acid and lysine rich protein 1. (626 aa)
RBM8ARNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. (174 aa)
ZC3H13Zinc finger CCCH-type containing 13. (1625 aa)
ENSMLEP00000030703SAP domain-containing protein. (173 aa)
CSTF3Cleavage stimulation factor subunit 3. (717 aa)
ENSMLEP00000031093Uncharacterized protein. (136 aa)
NCBP2Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (89 aa)
C12orf50Chromosome 12 open reading frame 50. (414 aa)
LOC105536165RRM domain-containing protein. (256 aa)
SRSF1Serine and arginine rich splicing factor 1. (248 aa)
SYMPKSymplekin. (1304 aa)
MAGOHBMago homolog B, exon junction complex subunit. (148 aa)
SRSF9Serine and arginine rich splicing factor 9. (208 aa)
SRSF3Serine and arginine rich splicing factor 3. (164 aa)
THOC7THO complex 7. (201 aa)
POLDIP3DNA polymerase delta interacting protein 3. (283 aa)
NUDT21Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...] (227 aa)
SRSF11Serine and arginine rich splicing factor 11. (483 aa)
FIP1L1Factor interacting with PAPOLA and CPSF1. (594 aa)
LOC105554415Uncharacterized protein. (139 aa)
ZNF473Zinc finger protein 473. (871 aa)
MAGOHMago homolog, exon junction complex subunit. (149 aa)
CPSF1Cleavage and polyadenylation specific factor 1. (1460 aa)
ALYREFAly/REF export factor. (207 aa)
SNRPESmall nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. (92 aa)
CLP1Polyribonucleotide 5'-hydroxyl-kinase Clp1; Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double stranded DNA (dsDNA) and double-stranded DNA:RNA hybrids. dsRNA is phosphorylated more efficiently than dsDNA, and the RNA component of a DNA:RNA hybrid is phosphorylated more efficiently than the DNA component. Appears to have roles in both tRNA splicing and mRNA 3'-end formation. Component of the tRNA splicing endonuclease complex. Phosphorylates the 5'-terminus of the tRNA 3'-exon during tRNA splicing; thi [...] (436 aa)
DDX39BDExD-box helicase 39B. (428 aa)
BCL2L2-PABPN1BCL2L2-PABPN1 readthrough. (333 aa)
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
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