STRINGSTRING
LOC105548167 LOC105548167 ZNF473 ZNF473 CPSF1 CPSF1 CPSF4 CPSF4 ENSMLEP00000024071 ENSMLEP00000024071 CSTF2 CSTF2 ENSMLEP00000025623 ENSMLEP00000025623 SNRPE SNRPE CLP1 CLP1 BCL2L2-PABPN1 BCL2L2-PABPN1 WDR33 WDR33 NCBP2 NCBP2 CSTF3 CSTF3 FIP1L1 FIP1L1 CPSF4L CPSF4L SNRPD3 SNRPD3 NUDT21 NUDT21 SYMPK SYMPK ENSMLEP00000000335 ENSMLEP00000000335 CPSF6 CPSF6 CSTF1 CSTF1 ENSMLEP00000004386 ENSMLEP00000004386 SNRPB SNRPB PCF11 PCF11 ENSMLEP00000005622 ENSMLEP00000005622 SLBP SLBP LSM10 LSM10 CPSF3 CPSF3 LSM11 LSM11 ENSMLEP00000008607 ENSMLEP00000008607 CPSF2 CPSF2 NCBP1 NCBP1 ENSMLEP00000013046 ENSMLEP00000013046 CPSF7 CPSF7 SNRPG SNRPG ENSMLEP00000016299 ENSMLEP00000016299 PAPOLA PAPOLA SNRPF SNRPF ENSMLEP00000020013 ENSMLEP00000020013
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC105548167RRM domain-containing protein. (275 aa)
ZNF473Zinc finger protein 473. (871 aa)
CPSF1Cleavage and polyadenylation specific factor 1. (1460 aa)
CPSF4Cleavage and polyadenylation specific factor 4. (269 aa)
ENSMLEP00000024071Sm domain-containing protein. (71 aa)
CSTF2Cleavage stimulation factor subunit 2. (597 aa)
ENSMLEP00000025623Small nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. (90 aa)
SNRPESmall nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. (92 aa)
CLP1Polyribonucleotide 5'-hydroxyl-kinase Clp1; Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double stranded DNA (dsDNA) and double-stranded DNA:RNA hybrids. dsRNA is phosphorylated more efficiently than dsDNA, and the RNA component of a DNA:RNA hybrid is phosphorylated more efficiently than the DNA component. Appears to have roles in both tRNA splicing and mRNA 3'-end formation. Component of the tRNA splicing endonuclease complex. Phosphorylates the 5'-terminus of the tRNA 3'-exon during tRNA splicing; thi [...] (436 aa)
BCL2L2-PABPN1BCL2L2-PABPN1 readthrough. (333 aa)
WDR33WD repeat domain 33. (1336 aa)
NCBP2Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (89 aa)
CSTF3Cleavage stimulation factor subunit 3. (717 aa)
FIP1L1Factor interacting with PAPOLA and CPSF1. (594 aa)
CPSF4LCleavage and polyadenylation specific factor 4 like. (179 aa)
SNRPD3Small nuclear ribonucleoprotein Sm D3; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing. (126 aa)
NUDT21Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...] (227 aa)
SYMPKSymplekin. (1304 aa)
ENSMLEP00000000335Small nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (76 aa)
CPSF6Cleavage and polyadenylation specific factor 6. (568 aa)
CSTF1Cleavage stimulation factor subunit 1. (431 aa)
ENSMLEP00000004386Small nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. (85 aa)
SNRPBSmall nuclear ribonucleoprotein-associated protein. (240 aa)
PCF11PCF11 cleavage and polyadenylation factor subunit. (1555 aa)
ENSMLEP00000005622Small nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. (85 aa)
SLBPStem-loop binding protein. (257 aa)
LSM10LSM10, U7 small nuclear RNA associated. (123 aa)
CPSF3Cleavage and polyadenylation specific factor 3. (684 aa)
LSM11LSM11, U7 small nuclear RNA associated. (210 aa)
ENSMLEP00000008607Small nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (70 aa)
CPSF2Cleavage and polyadenylation specificity factor subunit 2. (782 aa)
NCBP1Nuclear cap binding protein subunit 1. (790 aa)
ENSMLEP00000013046Small nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (74 aa)
CPSF7Cleavage and polyadenylation specific factor 7. (489 aa)
SNRPGSmall nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (96 aa)
ENSMLEP00000016299Uncharacterized protein. (54 aa)
PAPOLAPoly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's. (745 aa)
SNRPFSm domain-containing protein. (127 aa)
ENSMLEP00000020013annotation not available (74 aa)
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
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