STRINGSTRING
MMP3 MMP3 ZDHHC7 ZDHHC7 GNG13 GNG13 AKT3 AKT3 PRMT1 PRMT1 HRAS HRAS SHC1 SHC1 GNG8 GNG8 SRC SRC MMP9 MMP9 GNAI1 GNAI1 PIK3R1 PIK3R1 GNGT1 GNGT1 ENSMLEP00000033047 ENSMLEP00000033047 HBEGF HBEGF CAV2 CAV2 HSP90AA1 HSP90AA1 FOS FOS ESR1 ESR1 EREG EREG STRN4 STRN4 GNG4 GNG4 LOC105546715 LOC105546715 PIK3R3 PIK3R3 NRAS NRAS GNG3 GNG3 GNG5 GNG5 UHMK1 UHMK1 CSDE1 CSDE1 GNG12 GNG12 ENSMLEP00000028401 ENSMLEP00000028401 MMP2 MMP2 AKT1 AKT1 ENSMLEP00000027485 ENSMLEP00000027485 GNAI3 GNAI3 GNGT2 GNGT2 SPHK1 SPHK1 IGF1R IGF1R EGFR EGFR ESR2 ESR2 GNB2 GNB2 MAPK1 MAPK1 ZDHHC21 ZDHHC21 FOXO3 FOXO3 AKT2 AKT2 MAPK3 MAPK3 GNB1 GNB1 PIK3CA PIK3CA WDR64 WDR64 CREB1 CREB1 STRN STRN PRKCZ PRKCZ TGFA TGFA XPO1 XPO1 PTK2 PTK2 NOS3 NOS3 EPGN EPGN GNAT3 GNAT3 MMP7 MMP7 PDPK1 PDPK1 CDKN1B CDKN1B CAV1 CAV1 ENSMLEP00000009841 ENSMLEP00000009841 AREG AREG LOC105550079 LOC105550079 GNG2 GNG2 S1PR3 S1PR3 KRAS KRAS ELK1 ELK1 ENSMLEP00000007417 ENSMLEP00000007417 ERAS ERAS GNB3 GNB3 EGF EGF GNAI2 GNAI2 BCL2 BCL2 BTC BTC GNB4 GNB4 SRF SRF PRMT8 PRMT8 ENSMLEP00000001951 ENSMLEP00000001951 PIK3R2 PIK3R2 STRN3 STRN3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MMP3Matrix metallopeptidase 3. (477 aa)
ZDHHC7Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (344 aa)
GNG13Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (67 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
PRMT1Protein arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (371 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
SHC1SHC adaptor protein 1. (584 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
SRCTyrosine-protein kinase. (542 aa)
MMP9Matrix metallopeptidase 9. (707 aa)
GNAI1G protein subunit alpha i1. (314 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
GNGT1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
ENSMLEP00000033047Uncharacterized protein. (67 aa)
HBEGFHeparin binding EGF like growth factor. (208 aa)
CAV2Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (140 aa)
HSP90AA1Heat shock protein 90 alpha family class A member 1. (823 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
ESR1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (595 aa)
EREGEpiregulin. (169 aa)
STRN4Striatin 4. (666 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
LOC105546715Uncharacterized protein. (319 aa)
PIK3R3Phosphoinositide-3-kinase regulatory subunit 3. (461 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
GNG5Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
UHMK1U2AF homology motif kinase 1. (419 aa)
CSDE1Cold shock domain containing E1. (844 aa)
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
ENSMLEP00000028401Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (65 aa)
MMP2Matrix metallopeptidase 2. (660 aa)
AKT1Non-specific serine/threonine protein kinase. (432 aa)
ENSMLEP00000027485PID domain-containing protein. (488 aa)
GNAI3G protein subunit alpha i3. (354 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (88 aa)
SPHK1Sphingosine kinase 1. (470 aa)
IGF1RTyrosine-protein kinase receptor. (1281 aa)
EGFRReceptor protein-tyrosine kinase. (1188 aa)
ESR2Estrogen receptor 2. (530 aa)
GNB2G protein subunit beta 2. (340 aa)
MAPK1Mitogen-activated protein kinase. (343 aa)
ZDHHC21Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (265 aa)
FOXO3Forkhead box O3. (670 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (364 aa)
GNB1G protein subunit beta 1. (340 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
WDR64WD repeat domain 64. (983 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
STRNStriatin. (702 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (596 aa)
TGFATransforming growth factor alpha. (166 aa)
XPO1Exportin 1. (1070 aa)
PTK2Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1096 aa)
NOS3Nitric oxide synthase; Produces nitric oxide (NO). (1155 aa)
EPGNEpithelial mitogen. (154 aa)
GNAT3G protein subunit alpha transducin 3. (354 aa)
MMP7Matrix metallopeptidase 7. (267 aa)
PDPK13-phosphoinositide dependent protein kinase 1. (529 aa)
CDKN1BCyclin dependent kinase inhibitor 1B. (198 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (147 aa)
ENSMLEP00000009841Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (310 aa)
AREGAmphiregulin. (274 aa)
LOC105550079Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (110 aa)
S1PR3Sphingosine-1-phosphate receptor 3; Belongs to the G-protein coupled receptor 1 family. (378 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
ELK1ETS transcription factor ELK1. (428 aa)
ENSMLEP00000007417Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
ERASES cell expressed Ras. (233 aa)
GNB3G protein subunit beta 3. (340 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1152 aa)
GNAI2G protein subunit alpha i2. (352 aa)
BCL2BCL2 apoptosis regulator. (239 aa)
BTCBetacellulin. (178 aa)
GNB4G protein subunit beta 4. (340 aa)
SRFSerum response factor. (434 aa)
PRMT8Protein arginine methyltransferase 8; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (394 aa)
ENSMLEP00000001951Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (60 aa)
PIK3R2Uncharacterized protein. (587 aa)
STRN3Striatin 3. (797 aa)
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
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