16 items (Mandrillus leucophaeus) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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Your Input:
	FTH1	Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (199 aa)
	CLCN2	Chloride voltage-gated channel 2. (898 aa)
	ATOX1	HMA domain-containing protein. (73 aa)
	CALM1	Calmodulin 1; Belongs to the calmodulin family. (149 aa)
	TLR4	Toll like receptor 4; Belongs to the Toll-like receptor family. (843 aa)
	PDLIM3	PDZ and LIM domain 3. (326 aa)
	SCN8A	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1980 aa)
	VDAC2	Voltage dependent anion channel 2. (308 aa)
	CALM2	Calmodulin 2. (149 aa)
	CACNA1G	Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2360 aa)
	TRPM6	Transient receptor potential cation channel subfamily M member 6. (2032 aa)
	ADCY1	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (338 aa)
	ICAM2	Intercellular adhesion molecule 2. (275 aa)
	CCKBR	Cholecystokinin B receptor; Belongs to the G-protein coupled receptor 1 family. (447 aa)
	MCU	Mitochondrial calcium uniporter. (318 aa)
	KCNC2	Potassium voltage-gated channel subfamily C member 2; Belongs to the potassium channel family. (638 aa)

Your Current Organism:

Mandrillus leucophaeus

NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADCY1	CACNA1G	ENSMLEP00000023897	ENSMLEP00000022108	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...]	0.714
ADCY1	CALM1	ENSMLEP00000023897	ENSMLEP00000010731	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Calmodulin 1; Belongs to the calmodulin family.	0.626
ADCY1	CALM2	ENSMLEP00000023897	ENSMLEP00000019375	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Calmodulin 2.	0.626
ADCY1	CCKBR	ENSMLEP00000023897	ENSMLEP00000032834	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Cholecystokinin B receptor; Belongs to the G-protein coupled receptor 1 family.	0.722
ADCY1	CLCN2	ENSMLEP00000023897	ENSMLEP00000007827	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Chloride voltage-gated channel 2.	0.474
ADCY1	KCNC2	ENSMLEP00000023897	ENSMLEP00000000805	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Potassium voltage-gated channel subfamily C member 2; Belongs to the potassium channel family.	0.449
ADCY1	PDLIM3	ENSMLEP00000023897	ENSMLEP00000015957	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	PDZ and LIM domain 3.	0.441
ADCY1	SCN8A	ENSMLEP00000023897	ENSMLEP00000016945	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	0.424
ADCY1	TRPM6	ENSMLEP00000023897	ENSMLEP00000023522	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Transient receptor potential cation channel subfamily M member 6.	0.415
ADCY1	VDAC2	ENSMLEP00000023897	ENSMLEP00000018690	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Voltage dependent anion channel 2.	0.706
ATOX1	CACNA1G	ENSMLEP00000010446	ENSMLEP00000022108	HMA domain-containing protein.	Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...]	0.605
ATOX1	CALM1	ENSMLEP00000010446	ENSMLEP00000010731	HMA domain-containing protein.	Calmodulin 1; Belongs to the calmodulin family.	0.427
ATOX1	CALM2	ENSMLEP00000010446	ENSMLEP00000019375	HMA domain-containing protein.	Calmodulin 2.	0.427
ATOX1	CCKBR	ENSMLEP00000010446	ENSMLEP00000032834	HMA domain-containing protein.	Cholecystokinin B receptor; Belongs to the G-protein coupled receptor 1 family.	0.616
ATOX1	CLCN2	ENSMLEP00000010446	ENSMLEP00000007827	HMA domain-containing protein.	Chloride voltage-gated channel 2.	0.645
ATOX1	ICAM2	ENSMLEP00000010446	ENSMLEP00000025033	HMA domain-containing protein.	Intercellular adhesion molecule 2.	0.420
ATOX1	KCNC2	ENSMLEP00000010446	ENSMLEP00000000805	HMA domain-containing protein.	Potassium voltage-gated channel subfamily C member 2; Belongs to the potassium channel family.	0.673
ATOX1	MCU	ENSMLEP00000010446	ENSMLEP00000036537	HMA domain-containing protein.	Mitochondrial calcium uniporter.	0.483
ATOX1	PDLIM3	ENSMLEP00000010446	ENSMLEP00000015957	HMA domain-containing protein.	PDZ and LIM domain 3.	0.637
ATOX1	SCN8A	ENSMLEP00000010446	ENSMLEP00000016945	HMA domain-containing protein.	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	0.555