STRINGSTRING
WDR90 WDR90 MSI1 MSI1 CPSF6 CPSF6 ENSMLEP00000001471 ENSMLEP00000001471 MKRN3 MKRN3 MKRN2 MKRN2 PPP2R5E PPP2R5E DDX39A DDX39A ZC3H4 ZC3H4 PYM1 PYM1 GLE1 GLE1 PPP2R2D PPP2R2D LOC105535476 LOC105535476 UPF3B UPF3B ENSMLEP00000003269 ENSMLEP00000003269 UPF3A UPF3A COPS5 COPS5 CSTF1 CSTF1 CZIB CZIB SAP18 SAP18 RNF141 RNF141 LOC105536411 LOC105536411 PCF11 PCF11 TWF1 TWF1 NEDD1 NEDD1 PPP2R5C PPP2R5C BOLL BOLL PPP2R2C PPP2R2C NXF1 NXF1 CPSF3 CPSF3 NXT1 NXT1 LOC105551588 LOC105551588 LOC105540517 LOC105540517 TWF2 TWF2 PABPC1 PABPC1 ENSMLEP00000007689 ENSMLEP00000007689 INTS9 INTS9 PPP2R5A PPP2R5A PABPC5 PABPC5 PPP4R4 PPP4R4 PPP1CA PPP1CA UPF1 UPF1 GSPT1 GSPT1 RBMX2 RBMX2 CASC3 CASC3 PPP2R2B PPP2R2B CPSF2 CPSF2 DCLRE1A DCLRE1A SMG6 SMG6 PPP2R3A PPP2R3A PPP2R1A PPP2R1A TMEM223 TMEM223 ZC3H8 ZC3H8 RBBP6 RBBP6 NXF3 NXF3 ST13 ST13 NCBP1 NCBP1 DDX19A DDX19A PPP1CB PPP1CB MORN1 MORN1 PPP4R1 PPP4R1 ETF1 ETF1 CPSF7 CPSF7 PPP2CA PPP2CA LOC105553827 LOC105553827 ENSMLEP00000015784 ENSMLEP00000015784 WDR82 WDR82 ENSMLEP00000016142 ENSMLEP00000016142 PAPOLA PAPOLA ENSMLEP00000016605 ENSMLEP00000016605 PABPN1L PABPN1L EIF2A EIF2A EIF4A3 EIF4A3 MSL1 MSL1 MKRN1 MKRN1 PNN PNN PIH1D3 PIH1D3 ENSMLEP00000018038 ENSMLEP00000018038 MSI2 MSI2 LOC105548167 LOC105548167 CPSF4 CPSF4 PPP2CB PPP2CB DAZAP1 DAZAP1 RNMT RNMT PPP2R5D PPP2R5D DCLRE1B DCLRE1B PARP12 PARP12 ENSMLEP00000023964 ENSMLEP00000023964 UPF2 UPF2 JAZF1 JAZF1 SMG1 SMG1 RNGTT RNGTT ENSMLEP00000024890 ENSMLEP00000024890 CSTF2 CSTF2 RNPS1 RNPS1 ACIN1 ACIN1 LOC105547341 LOC105547341 SMG7 SMG7 WDR33 WDR33 ZGRF1 ZGRF1 FUS FUS WDR77 WDR77 PPP1CC PPP1CC ZC3H3 ZC3H3 SRRM1 SRRM1 CIRBP CIRBP LOC105538326 LOC105538326 CPSF4L CPSF4L ZC3H6 ZC3H6 PELO PELO RBM8A RBM8A PAPOLG PAPOLG CSTF3 CSTF3 DUSP11 DUSP11 ENSMLEP00000031093 ENSMLEP00000031093 SERAC1 SERAC1 NCBP2 NCBP2 LOC105536165 LOC105536165 LOC105554868 LOC105554868 TUT1 TUT1 TMEM258 TMEM258 SYMPK SYMPK MAGOHB MAGOHB PABPC4 PABPC4 PPP2R2A PPP2R2A PPP1R42 PPP1R42 NXT2 NXT2 SMG5 SMG5 POLDIP3 POLDIP3 PPP2R5B PPP2R5B NUDT21 NUDT21 ENSMLEP00000034998 ENSMLEP00000034998 ENSMLEP00000035052 ENSMLEP00000035052 DDX25 DDX25 FNBP4 FNBP4 RBM3 RBM3 FIP1L1 FIP1L1 CFAP20 CFAP20 TARDBP TARDBP YTHDC1 YTHDC1 PABPC3 PABPC3 LOC105554415 LOC105554415 MAGOH MAGOH LOC105537224 LOC105537224 CPSF1 CPSF1 PABPC1L PABPC1L ENSMLEP00000038335 ENSMLEP00000038335 HBS1L HBS1L C3orf67 C3orf67 PPP2R1B PPP2R1B ALYREF ALYREF LOC105549824 LOC105549824 CLP1 CLP1 ENSMLEP00000039270 ENSMLEP00000039270 DDX39B DDX39B BCL2L2-PABPN1 BCL2L2-PABPN1 ENSMLEP00000040526 ENSMLEP00000040526 INTS11 INTS11
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
WDR90WD repeat domain 90. (1750 aa)
MSI1Musashi RNA binding protein 1. (328 aa)
CPSF6Cleavage and polyadenylation specific factor 6. (568 aa)
ENSMLEP00000001471RRM domain-containing protein. (317 aa)
MKRN3Uncharacterized protein. (182 aa)
MKRN2Makorin ring finger protein 2. (405 aa)
PPP2R5ESerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (468 aa)
DDX39ADExD-box helicase 39A. (435 aa)
ZC3H4Zinc finger CCCH-type containing 4. (1249 aa)
PYM1PYM homolog 1, exon junction complex associated factor. (204 aa)
GLE1GLE1 RNA export mediator. (674 aa)
PPP2R2DSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (466 aa)
LOC105535476Uncharacterized protein. (527 aa)
UPF3BUPF3B regulator of nonsense mediated mRNA decay. (483 aa)
ENSMLEP00000003269MPN domain-containing protein. (334 aa)
UPF3AUPF3A regulator of nonsense mediated mRNA decay. (419 aa)
COPS5MPN domain-containing protein. (334 aa)
CSTF1Cleavage stimulation factor subunit 1. (431 aa)
CZIBCXXC motif containing zinc binding protein. (158 aa)
SAP18Sin3A associated protein 18. (172 aa)
RNF141Ring finger protein 141. (230 aa)
LOC105536411STI1 domain-containing protein. (311 aa)
PCF11PCF11 cleavage and polyadenylation factor subunit. (1555 aa)
TWF1Twinfilin actin binding protein 1. (384 aa)
NEDD1NEDD1 gamma-tubulin ring complex targeting factor. (663 aa)
PPP2R5CSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (580 aa)
BOLLBoule homolog, RNA binding protein. (320 aa)
PPP2R2CSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (447 aa)
NXF1Nuclear RNA export factor 1. (619 aa)
CPSF3Cleavage and polyadenylation specific factor 3. (684 aa)
NXT1Nuclear transport factor 2 like export factor 1. (140 aa)
LOC105551588Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (455 aa)
LOC105540517Uncharacterized protein. (200 aa)
TWF2Twinfilin actin binding protein 2. (349 aa)
PABPC1Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (634 aa)
ENSMLEP00000007689RRM domain-containing protein. (157 aa)
INTS9Integrator complex subunit 9. (675 aa)
PPP2R5ASerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (525 aa)
PABPC5Poly(A) binding protein cytoplasmic 5. (382 aa)
PPP4R4Protein phosphatase 4 regulatory subunit 4. (843 aa)
PPP1CASerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (355 aa)
UPF1UPF1 RNA helicase and ATPase. (1052 aa)
GSPT1G1 to S phase transition 1. (519 aa)
RBMX2RNA binding motif protein X-linked 2. (322 aa)
CASC3CASC3 exon junction complex subunit. (634 aa)
PPP2R2BSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (509 aa)
CPSF2Cleavage and polyadenylation specificity factor subunit 2. (782 aa)
DCLRE1ADNA cross-link repair 1A. (1012 aa)
SMG6SMG6 nonsense mediated mRNA decay factor. (1379 aa)
PPP2R3AProtein phosphatase 2 regulatory subunit B''alpha. (1150 aa)
PPP2R1AProtein phosphatase 2 scaffold subunit Aalpha. (589 aa)
TMEM223Transmembrane protein 223. (194 aa)
ZC3H8Zinc finger CCCH-type containing 8. (295 aa)
RBBP6RB binding protein 6, ubiquitin ligase. (1792 aa)
NXF3Nuclear RNA export factor 3. (544 aa)
ST13ST13 Hsp70 interacting protein. (305 aa)
NCBP1Nuclear cap binding protein subunit 1. (790 aa)
DDX19ADEAD-box helicase 19A. (478 aa)
PPP1CBSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (322 aa)
MORN1MORN repeat containing 1. (437 aa)
PPP4R1Protein phosphatase 4 regulatory subunit 1. (919 aa)
ETF1eRF1_1 domain-containing protein. (423 aa)
CPSF7Cleavage and polyadenylation specific factor 7. (489 aa)
PPP2CASerine/threonine-protein phosphatase. (275 aa)
LOC105553827HipN domain-containing protein. (219 aa)
ENSMLEP00000015784Uncharacterized protein. (271 aa)
WDR82WD repeat domain 82. (314 aa)
ENSMLEP00000016142PWI domain-containing protein. (761 aa)
PAPOLAPoly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's. (745 aa)
ENSMLEP00000016605Uncharacterized protein. (119 aa)
PABPN1LPoly(A) binding protein nuclear 1 like, cytoplasmic. (275 aa)
EIF2AEukaryotic translation initiation factor 2A; Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl- tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner. (586 aa)
EIF4A3Eukaryotic translation initiation factor 4A3; Belongs to the DEAD box helicase family. (354 aa)
MSL1MSL complex subunit 1. (413 aa)
MKRN1Makorin ring finger protein 1. (420 aa)
PNNPinin, desmosome associated protein. (717 aa)
PIH1D3PIH1 domain containing 3. (209 aa)
ENSMLEP00000018038Uncharacterized protein. (427 aa)
MSI2Musashi RNA binding protein 2. (324 aa)
LOC105548167RRM domain-containing protein. (275 aa)
CPSF4Cleavage and polyadenylation specific factor 4. (269 aa)
PPP2CBSerine/threonine-protein phosphatase. (275 aa)
DAZAP1DAZ associated protein 1. (397 aa)
RNMTmRNA cap guanine-N7 methyltransferase. (504 aa)
PPP2R5DSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (605 aa)
DCLRE1BDNA cross-link repair 1B. (532 aa)
PARP12Poly(ADP-ribose) polymerase family member 12. (618 aa)
ENSMLEP00000023964Uncharacterized protein. (190 aa)
UPF2UPF2 regulator of nonsense mediated mRNA decay. (1262 aa)
JAZF1JAZF zinc finger 1. (219 aa)
SMG1SMG1 nonsense mediated mRNA decay associated PI3K related kinase; Belongs to the PI3/PI4-kinase family. (3635 aa)
RNGTTPolynucleotide 5'-triphosphatase; Bifunctional mRNA-capping enzyme exhibiting RNA 5'- triphosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the gmp moiety of GTP to the 5'-diphosphate terminus. (597 aa)
ENSMLEP00000024890Uncharacterized protein. (54 aa)
CSTF2Cleavage stimulation factor subunit 2. (597 aa)
RNPS1RNA binding protein with serine rich domain 1. (305 aa)
ACIN1Apoptotic chromatin condensation inducer 1. (1340 aa)
LOC105547341RRM domain-containing protein. (255 aa)
SMG7SMG7 nonsense mediated mRNA decay factor. (1170 aa)
WDR33WD repeat domain 33. (1336 aa)
ZGRF1Zinc finger GRF-type containing 1. (2046 aa)
FUSFUS RNA binding protein. (522 aa)
WDR77WD repeat domain 77. (342 aa)
PPP1CCSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (355 aa)
ZC3H3Zinc finger CCCH-type containing 3. (950 aa)
SRRM1PWI domain-containing protein. (898 aa)
CIRBPCold inducible RNA binding protein. (304 aa)
LOC105538326WRNPLPNID domain-containing protein. (953 aa)
CPSF4LCleavage and polyadenylation specific factor 4 like. (179 aa)
ZC3H6Zinc finger CCCH-type containing 6. (1188 aa)
PELOProtein pelota homolog; May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non- functional ribosomes and degrade damaged mRNAs. (385 aa)
RBM8ARNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. (174 aa)
PAPOLGPoly(A) polymerase gamma. (736 aa)
CSTF3Cleavage stimulation factor subunit 3. (717 aa)
DUSP11Dual specificity phosphatase 11. (378 aa)
ENSMLEP00000031093Uncharacterized protein. (136 aa)
SERAC1Serine active site containing 1. (654 aa)
NCBP2Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (89 aa)
LOC105536165RRM domain-containing protein. (256 aa)
LOC105554868eRF1_1 domain-containing protein. (420 aa)
TUT1RRM domain-containing protein. (908 aa)
TMEM258Transmembrane protein 258. (79 aa)
SYMPKSymplekin. (1304 aa)
MAGOHBMago homolog B, exon junction complex subunit. (148 aa)
PABPC4Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (660 aa)
PPP2R2ASerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (457 aa)
PPP1R42Protein phosphatase 1 regulatory subunit 42. (357 aa)
NXT2Nuclear transport factor 2 like export factor 2. (197 aa)
SMG5SMG5 nonsense mediated mRNA decay factor. (985 aa)
POLDIP3DNA polymerase delta interacting protein 3. (283 aa)
PPP2R5BSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (502 aa)
NUDT21Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...] (227 aa)
ENSMLEP00000034998Uncharacterized protein. (437 aa)
ENSMLEP00000035052Uncharacterized protein. (441 aa)
DDX25DEAD-box helicase 25. (483 aa)
FNBP4Formin binding protein 4. (1017 aa)
RBM3RRM domain-containing protein. (157 aa)
FIP1L1Factor interacting with PAPOLA and CPSF1. (594 aa)
CFAP20Cilia and flagella associated protein 20. (193 aa)
TARDBPTAR DNA binding protein. (414 aa)
YTHDC1YTH domain containing 1. (731 aa)
PABPC3Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (630 aa)
LOC105554415Uncharacterized protein. (139 aa)
MAGOHMago homolog, exon junction complex subunit. (149 aa)
LOC105537224Uncharacterized protein. (471 aa)
CPSF1Cleavage and polyadenylation specific factor 1. (1460 aa)
PABPC1LPolyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (614 aa)
ENSMLEP00000038335Uncharacterized protein. (575 aa)
HBS1LHBS1 like translational GTPase. (698 aa)
C3orf67Chromosome 3 open reading frame 67. (691 aa)
PPP2R1BProtein phosphatase 2 scaffold subunit Abeta. (637 aa)
ALYREFAly/REF export factor. (207 aa)
LOC105549824STI1 domain-containing protein. (344 aa)
CLP1Polyribonucleotide 5'-hydroxyl-kinase Clp1; Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double stranded DNA (dsDNA) and double-stranded DNA:RNA hybrids. dsRNA is phosphorylated more efficiently than dsDNA, and the RNA component of a DNA:RNA hybrid is phosphorylated more efficiently than the DNA component. Appears to have roles in both tRNA splicing and mRNA 3'-end formation. Component of the tRNA splicing endonuclease complex. Phosphorylates the 5'-terminus of the tRNA 3'-exon during tRNA splicing; thi [...] (436 aa)
ENSMLEP00000039270Uncharacterized protein. (139 aa)
DDX39BDExD-box helicase 39B. (428 aa)
BCL2L2-PABPN1BCL2L2-PABPN1 readthrough. (333 aa)
ENSMLEP00000040526TDP43_N domain-containing protein. (153 aa)
INTS11Integrator complex subunit 11. (515 aa)
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
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