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SH3GLB1 | SH3 domain containing GRB2 like, endophilin B1. (394 aa) | ||||
TTC14 | Tetratricopeptide repeat domain 14. (771 aa) | ||||
RRAGD | Ras related GTP binding D. (400 aa) | ||||
ENSMLEP00000001074 | Uncharacterized protein. (172 aa) | ||||
RRAGB | Ras related GTP binding B. (374 aa) | ||||
ENSMLEP00000001381 | Uncharacterized protein. (188 aa) | ||||
RAB7B | RAB7B, member RAS oncogene family. (199 aa) | ||||
PIK3R2 | Uncharacterized protein. (587 aa) | ||||
STX17 | Syntaxin 17; Belongs to the syntaxin family. (302 aa) | ||||
EIF2AK3 | Eukaryotic translation initiation factor 2 alpha kinase 3. (1012 aa) | ||||
TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (522 aa) | ||||
TSSK6 | Testis specific serine kinase 6; Belongs to the protein kinase superfamily. (273 aa) | ||||
LAMP1 | Lysosomal associated membrane protein 1. (410 aa) | ||||
ENSMLEP00000003274 | Uncharacterized protein. (105 aa) | ||||
BAD | BCL2 associated agonist of cell death. (167 aa) | ||||
PRKAA2 | Non-specific serine/threonine protein kinase. (542 aa) | ||||
LOC105550167 | Uncharacterized protein. (298 aa) | ||||
MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa) | ||||
GABARAPL2 | GABA type A receptor associated protein like 2. (117 aa) | ||||
REM1 | GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (298 aa) | ||||
RRAGA | Ras related GTP binding A. (313 aa) | ||||
BCL2 | BCL2 apoptosis regulator. (239 aa) | ||||
RRAS | RAS related. (218 aa) | ||||
MAPK10 | Mitogen-activated protein kinase. (477 aa) | ||||
ZFYVE28 | Zinc finger FYVE-type containing 28. (889 aa) | ||||
PDIK1L | PDLIM1 interacting kinase 1 like; Belongs to the protein kinase superfamily. (341 aa) | ||||
HMGB4 | High mobility group box 4. (191 aa) | ||||
ERAS | ES cell expressed Ras. (233 aa) | ||||
ATG7 | Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] (704 aa) | ||||
DUS2 | Dihydrouridine synthase 2. (464 aa) | ||||
RPS6KB1 | Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa) | ||||
MAPK9 | Mitogen-activated protein kinase. (395 aa) | ||||
STK35 | Serine/threonine kinase 35. (363 aa) | ||||
ATG13 | Autophagy-related protein 13; Belongs to the ATG13 family. Metazoan subfamily. (550 aa) | ||||
SNAP47 | Synaptosome associated protein 47. (419 aa) | ||||
ENSMLEP00000008243 | Uncharacterized protein. (132 aa) | ||||
KRAS | KRAS proto-oncogene, GTPase. (189 aa) | ||||
ATG4B | Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (403 aa) | ||||
ENSMLEP00000008760 | Uncharacterized protein. (169 aa) | ||||
ATG16L1 | Autophagy related 16 like 1. (624 aa) | ||||
RPS6KB2 | Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (487 aa) | ||||
DAPK3 | Death associated protein kinase 3. (288 aa) | ||||
IRS4 | Insulin receptor substrate 4. (1245 aa) | ||||
RAB39B | RAB39B, member RAS oncogene family. (213 aa) | ||||
RHEB | Ras homolog, mTORC1 binding. (181 aa) | ||||
ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1. (2731 aa) | ||||
PRKX | Protein kinase X-linked. (304 aa) | ||||
LOC105545212 | Uncharacterized protein. (749 aa) | ||||
IRS1 | Insulin receptor substrate 1. (1242 aa) | ||||
CFLAR | CASP8 and FADD like apoptosis regulator; Belongs to the peptidase C14A family. (480 aa) | ||||
RAF1 | Raf-1 proto-oncogene, serine/threonine kinase. (668 aa) | ||||
PDPK1 | 3-phosphoinositide dependent protein kinase 1. (529 aa) | ||||
C9orf72 | C9orf72-SMCR8 complex subunit. (481 aa) | ||||
SUPT20H | SPT20 homolog, SAGA complex component. (779 aa) | ||||
SUPT20HL1 | Uncharacterized protein. (811 aa) | ||||
RIT1 | Ras like without CAAX 1. (236 aa) | ||||
ATG14 | Autophagy related 14. (486 aa) | ||||
TPTE2 | Uncharacterized protein. (550 aa) | ||||
LOC105532112 | Uncharacterized protein. (188 aa) | ||||
HIF3A | Hypoxia inducible factor 3 subunit alpha. (669 aa) | ||||
GEM | GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (295 aa) | ||||
ATG12 | Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (140 aa) | ||||
ENSMLEP00000013771 | PI3K/PI4K domain-containing protein; Belongs to the PI3/PI4-kinase family. (104 aa) | ||||
MTMR4 | Myotubularin related protein 4. (1199 aa) | ||||
PPP2CA | Serine/threonine-protein phosphatase. (275 aa) | ||||
ENSMLEP00000014760 | PI3K/PI4K domain-containing protein; Belongs to the PI3/PI4-kinase family. (94 aa) | ||||
MAP2K2 | Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (389 aa) | ||||
PRKCQ | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (706 aa) | ||||
RAB33A | RAB33A, member RAS oncogene family. (237 aa) | ||||
ENSMLEP00000015464 | Uncharacterized protein. (189 aa) | ||||
MAPK8 | Mitogen-activated protein kinase. (427 aa) | ||||
RB1CC1 | RB1 inducible coiled-coil 1. (1570 aa) | ||||
REM2 | GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (340 aa) | ||||
RAB19 | RAB19, member RAS oncogene family. (217 aa) | ||||
INS | Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa) | ||||
HIF1A | Hypoxia inducible factor 1 subunit alpha. (758 aa) | ||||
ATG2A | Autophagy related 2A. (1938 aa) | ||||
ENSMLEP00000016609 | Uncharacterized protein. (174 aa) | ||||
TSSK3 | Testis specific serine kinase 3. (268 aa) | ||||
ATG3 | Autophagy-related protein 3. (314 aa) | ||||
ENSMLEP00000016952 | Uncharacterized protein. (236 aa) | ||||
WIPI2 | WD repeat domain, phosphoinositide interacting 2. (258 aa) | ||||
BCL2L1 | BCL2 like 1. (233 aa) | ||||
HMGB3 | Uncharacterized protein. (155 aa) | ||||
RAB33B | RAB33B, member RAS oncogene family. (229 aa) | ||||
ENSMLEP00000018448 | Uncharacterized protein. (82 aa) | ||||
DAPK1 | Death associated protein kinase 1. (1430 aa) | ||||
IFITM10 | Interferon induced transmembrane protein 10. (192 aa) | ||||
DAPK2 | Death associated protein kinase 2; Belongs to the protein kinase superfamily. (488 aa) | ||||
ATG4A | Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (398 aa) | ||||
ERN1 | Endoplasmic reticulum to nucleus signaling 1. (959 aa) | ||||
TP53INP1 | Tumor protein p53 inducible nuclear protein 1. (241 aa) | ||||
PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) | ||||
ENSMLEP00000019711 | HMG box domain-containing protein. (175 aa) | ||||
RAB39A | RAB39A, member RAS oncogene family. (179 aa) | ||||
MAP2K1 | Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa) | ||||
ATG10 | Autophagy_act_C domain-containing protein. (112 aa) | ||||
ATG5 | Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa) | ||||
RASEF | RAS and EF-hand domain containing. (740 aa) | ||||
ENSMLEP00000020759 | Uncharacterized protein. (90 aa) | ||||
PRKACA | Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (352 aa) | ||||
MRAS | Muscle RAS oncogene homolog. (208 aa) | ||||
HMGB2 | Uncharacterized protein. (210 aa) | ||||
ENSMLEP00000021070 | C2 PI3K-type domain-containing protein; Belongs to the PI3/PI4-kinase family. (201 aa) | ||||
MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (364 aa) | ||||
ENSMLEP00000021326 | Uncharacterized protein. (200 aa) | ||||
LOC105529421 | Uncharacterized protein. (362 aa) | ||||
RUBCNL | Rubicon like autophagy enhancer. (661 aa) | ||||
NRBF2 | Nuclear receptor binding factor 2. (289 aa) | ||||
PPP2CB | Serine/threonine-protein phosphatase. (275 aa) | ||||
AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) | ||||
ATG9B | Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (921 aa) | ||||
VMP1 | Vacuole membrane protein 1. (406 aa) | ||||
ZFYVE1 | Zinc finger FYVE-type containing 1. (789 aa) | ||||
ATG16L2 | Autophagy related 16 like 2. (545 aa) | ||||
TBK1 | TANK binding kinase 1. (729 aa) | ||||
LMLN2 | Leishmanolysin-like peptidase. (768 aa) | ||||
DDIT4L | DNA damage inducible transcript 4 like. (193 aa) | ||||
BNIP3 | BCL2 interacting protein 3. (215 aa) | ||||
MAPK1 | Mitogen-activated protein kinase. (343 aa) | ||||
IGF1R | Tyrosine-protein kinase receptor. (1281 aa) | ||||
CRYGN | Crystallin gamma N; Belongs to the beta/gamma-crystallin family. (182 aa) | ||||
VAMP8 | Vesicle associated membrane protein 8. (100 aa) | ||||
ENSMLEP00000024805 | Protein kinase domain-containing protein. (365 aa) | ||||
CTSL | Cathepsin L; Belongs to the peptidase C1 family. (333 aa) | ||||
CTSB | Cathepsin B; Belongs to the peptidase C1 family. (339 aa) | ||||
TSC1 | TSC complex subunit 1. (1162 aa) | ||||
PTEN | Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa) | ||||
PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa) | ||||
HMGB1 | High mobility group box 1. (215 aa) | ||||
SQSTM1 | Sequestosome 1. (374 aa) | ||||
ENSMLEP00000026884 | Uncharacterized protein. (211 aa) | ||||
RUBCN | Rubicon autophagy regulator. (982 aa) | ||||
GABARAPL1 | GABA type A receptor associated protein like 1. (146 aa) | ||||
STK11 | Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (433 aa) | ||||
MTMR14 | Myotubularin related protein 14. (671 aa) | ||||
RIT2 | Ras like without CAAX 2. (217 aa) | ||||
AKT1 | Non-specific serine/threonine protein kinase. (432 aa) | ||||
EIF2AK4 | Eukaryotic translation initiation factor 2 alpha kinase 4. (1644 aa) | ||||
PIK3CB | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1073 aa) | ||||
GABARAP | GABA type A receptor-associated protein. (117 aa) | ||||
ATG9A | Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (850 aa) | ||||
ATG4D | Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (469 aa) | ||||
ENSMLEP00000029005 | ATG7_N domain-containing protein. (78 aa) | ||||
ENSMLEP00000029143 | Uncharacterized protein. (185 aa) | ||||
MTMR3 | Myotubularin related protein 3. (1207 aa) | ||||
CTSD | Cathepsin D; Belongs to the peptidase A1 family. (397 aa) | ||||
CSDE1 | Cold shock domain containing E1. (844 aa) | ||||
ENSMLEP00000029316 | PAS domain-containing protein. (190 aa) | ||||
ENSMLEP00000029567 | Uncharacterized protein. (158 aa) | ||||
SMCR8 | SMCR8-C9orf72 complex subunit. (936 aa) | ||||
MLST8 | MTOR associated protein, LST8 homolog. (335 aa) | ||||
TSC2 | TSC complex subunit 2. (1807 aa) | ||||
NRAS | NRAS proto-oncogene, GTPase. (189 aa) | ||||
DEPTOR | DEP domain containing MTOR interacting protein. (347 aa) | ||||
PPP1R14B | Uncharacterized protein. (127 aa) | ||||
MAP3K7 | Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa) | ||||
PIK3R3 | Phosphoinositide-3-kinase regulatory subunit 3. (461 aa) | ||||
WDR41 | WD repeat domain 41. (459 aa) | ||||
ATG4C | Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (458 aa) | ||||
RPTOR | Regulatory associated protein of MTOR complex 1. (1291 aa) | ||||
CRYBB3 | Uncharacterized protein; Belongs to the beta/gamma-crystallin family. (113 aa) | ||||
RRAS2 | RAS related 2. (176 aa) | ||||
KCNK1 | Potassium channel subfamily K member. (336 aa) | ||||
TANK | TRAF family member associated NFKB activator. (425 aa) | ||||
PRKACB | Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa) | ||||
ERN2 | Endoplasmic reticulum to nucleus signaling 2. (821 aa) | ||||
AMBRA1 | Autophagy and beclin 1 regulator 1. (1298 aa) | ||||
LAMP2 | Lysosomal associated membrane protein 2. (411 aa) | ||||
NOL4L | Nucleolar protein 4 like. (573 aa) | ||||
RAB7A | RAB7A, member RAS oncogene family. (207 aa) | ||||
RAB8A | RAB8A, member RAS oncogene family. (207 aa) | ||||
RAB43 | RAB43, member RAS oncogene family. (212 aa) | ||||
KIAA1671 | KIAA1671. (1758 aa) | ||||
NOL4 | Nucleolar protein 4. (638 aa) | ||||
PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (724 aa) | ||||
RRAGC | Ras related GTP binding C. (320 aa) | ||||
PRKCD | Protein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa) | ||||
DDIT4 | DNA damage inducible transcript 4. (233 aa) | ||||
PRKAA1 | Non-specific serine/threonine protein kinase. (559 aa) | ||||
ULK2 | Unc-51 like autophagy activating kinase 2. (1006 aa) | ||||
ENSMLEP00000034891 | Uncharacterized protein. (252 aa) | ||||
TSSK4 | Testis specific serine kinase 4. (338 aa) | ||||
EIF2S1 | Eukaryotic translation initiation factor 2 subunit alpha. (315 aa) | ||||
ENSMLEP00000035176 | Uncharacterized protein. (77 aa) | ||||
LMLN | Leishmanolysin-like peptidase. (692 aa) | ||||
RRAD | RRAD, Ras related glycolysis inhibitor and calcium channel regulator. (248 aa) | ||||
WIPI1 | WD repeat domain, phosphoinositide interacting 1. (446 aa) | ||||
PIK3R4 | Phosphoinositide-3-kinase regulatory subunit 4. (1358 aa) | ||||
HRAS | HRas proto-oncogene, GTPase. (189 aa) | ||||
AKT1S1 | AKT1 substrate 1. (276 aa) | ||||
ENSMLEP00000036883 | Uncharacterized protein. (205 aa) | ||||
RAB1A | Uncharacterized protein. (205 aa) | ||||
AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) | ||||
ULK1 | Unc-51 like autophagy activating kinase 1. (996 aa) | ||||
SNAP29 | Synaptosome associated protein 29. (258 aa) | ||||
ARID4A | AT-rich interaction domain 4A. (1262 aa) | ||||
RHEBL1 | RHEB like 1. (183 aa) | ||||
NPAS3 | Neuronal PAS domain protein 3. (931 aa) | ||||
ENSMLEP00000038778 | Uncharacterized protein. (300 aa) | ||||
ATG101 | Autophagy related 101. (218 aa) | ||||
TP53INP2 | Tumor protein p53 inducible nuclear protein 2. (220 aa) | ||||
UVRAG | UV radiation resistance associated. (681 aa) | ||||
ENSMLEP00000039335 | Uncharacterized protein. (147 aa) | ||||
ATG2B | Autophagy related 2B. (2079 aa) | ||||
ENSMLEP00000040499 | Uncharacterized protein. (147 aa) | ||||
CAMKK2 | Calcium/calmodulin dependent protein kinase kinase 2. (588 aa) | ||||
IGBP1 | Immunoglobulin binding protein 1. (339 aa) | ||||
BECN1 | Beclin 1. (450 aa) |