STRINGSTRING
SSPO SSPO RASGRP1 RASGRP1 ACTL8 ACTL8 LYN LYN GP9 GP9 PIK3R2 PIK3R2 VWF VWF TBXAS1 TBXAS1 F2 F2 PLCB3 PLCB3 MAPK14 MAPK14 ADCY6 ADCY6 MYLK4 MYLK4 SRMS SRMS ROCK1 ROCK1 FERMT3 FERMT3 AKT3 AKT3 ARHGAP35 ARHGAP35 ACTG1 ACTG1 RASGRP2 RASGRP2 GP1BA GP1BA SRC SRC LRRC15 LRRC15 BTK BTK VASP VASP FGG FGG TLN1 TLN1 GNAI1 GNAI1 PIK3R1 PIK3R1 GUCY1B1 GUCY1B1 FCER1G FCER1G TBXA2R TBXA2R PRKACB PRKACB MAPK13 MAPK13 SNAP23 SNAP23 PPP1R12A PPP1R12A GNA13 GNA13 SYK SYK GUCY1A1 GUCY1A1 RDH13 RDH13 FCGR2A FCGR2A PRKCI PRKCI PIK3R3 PIK3R3 PLA2G4B PLA2G4B PTGIR PTGIR ACTB ACTB TLN2 TLN2 JMJD7 JMJD7 ITGB1 ITGB1 LOC105553738 LOC105553738 RHOA RHOA COL1A2 COL1A2 PIK3CB PIK3CB AKT1 AKT1 PPP1CC PPP1CC RAP1B RAP1B MAPK12 MAPK12 ENSMLEP00000027131 ENSMLEP00000027131 ADCY3 ADCY3 GNAI3 GNAI3 PIK3CD PIK3CD ADCY5 ADCY5 LCP2 LCP2 ENSMLEP00000024790 ENSMLEP00000024790 VAMP8 VAMP8 PLCG2 PLCG2 LOC105548340 LOC105548340 ADCY1 ADCY1 MAPK1 MAPK1 MAPK11 MAPK11 PLCB2 PLCB2 PLA2G4C PLA2G4C ITPR3 ITPR3 LOC105548088 LOC105548088 ITGA2B ITGA2B AKT2 AKT2 PIK3R6 PIK3R6 MAPK3 MAPK3 PRKACA PRKACA COL1A1 COL1A1 GUCY1A2 GUCY1A2 LOC105540399 LOC105540399 F2R F2R PIK3CA PIK3CA ORAI1 ORAI1 FGA FGA ADCY2 ADCY2 STIM1 STIM1 PRKCZ PRKCZ FYN FYN ITGB3 ITGB3 MYLK MYLK PLA2G4A PLA2G4A NOS3 NOS3 MYLK3 MYLK3 PRKG2 PRKG2 PPP1CB PPP1CB ENSMLEP00000011903 ENSMLEP00000011903 GP6 GP6 LOC105553882 LOC105553882 LOC105542926 LOC105542926 PIK3CG PIK3CG MYLK2 MYLK2 PTK6 PTK6 ROCK2 ROCK2 ITPR1 ITPR1 GNAQ GNAQ PLCB4 PLCB4 PIK3R5 PIK3R5 ARHGEF1 ARHGEF1 RAP1A RAP1A PPP1CA PPP1CA PLCB1 PLCB1 MYL12A MYL12A ACTL7A ACTL7A ARHGEF12 ARHGEF12 P2RY1 P2RY1 ITPR2 ITPR2 GNAI2 GNAI2 ACTRT1 ACTRT1 PTGS1 PTGS1 APBB1IP APBB1IP ADCY8 ADCY8 RHOC RHOC P2RY12 P2RY12 MYL12B MYL12B ENSMLEP00000004779 ENSMLEP00000004779 P2RX1 P2RX1 ITGA2 ITGA2 FGB FGB GNAS GNAS PRKG1 PRKG1 ADCY7 ADCY7 ADCY9 ADCY9 FCGR2B FCGR2B ENSMLEP00000003080 ENSMLEP00000003080 DHRSX DHRSX ADCY4 ADCY4 ACTRT2 ACTRT2 ACTL7B ACTL7B PLA2G4F PLA2G4F PLA2G4E PLA2G4E COL3A1 COL3A1 PLA2G4D PLA2G4D ZNF408 ZNF408
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SSPOSCO-spondin. (5120 aa)
RASGRP1RAS guanyl releasing protein 1. (832 aa)
ACTL8Actin like 8; Belongs to the actin family. (366 aa)
LYNTyrosine-protein kinase. (470 aa)
GP9Glycoprotein IX platelet. (177 aa)
PIK3R2Uncharacterized protein. (587 aa)
VWFVon Willebrand factor. (2813 aa)
TBXAS1Thromboxane A synthase 1; Belongs to the cytochrome P450 family. (562 aa)
F2Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (623 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1245 aa)
MAPK14Mitogen-activated protein kinase. (350 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1168 aa)
MYLK4Myosin light chain kinase family member 4; Belongs to the protein kinase superfamily. (388 aa)
SRMSTyrosine-protein kinase. (489 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1368 aa)
FERMT3Fermitin family member 3. (663 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
ARHGAP35Rho GTPase activating protein 35. (1499 aa)
ACTG1Actin gamma 1. (376 aa)
RASGRP2RAS guanyl releasing protein 2. (609 aa)
GP1BAUncharacterized protein. (644 aa)
SRCTyrosine-protein kinase. (542 aa)
LRRC15Leucine rich repeat containing 15. (584 aa)
BTKTyrosine-protein kinase. (659 aa)
VASPVasodilator stimulated phosphoprotein. (432 aa)
FGGFibrinogen gamma chain. (453 aa)
TLN1Talin 1. (2547 aa)
GNAI1G protein subunit alpha i1. (314 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
GUCY1B1Guanylate cyclase 1 soluble subunit beta 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (554 aa)
FCER1GFc fragment of IgE receptor Ig. (112 aa)
TBXA2RThromboxane A2 receptor. (329 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
MAPK13Mitogen-activated protein kinase. (397 aa)
SNAP23Synaptosomal-associated protein; Belongs to the SNAP-25 family. (211 aa)
PPP1R12AProtein phosphatase 1 regulatory subunit. (990 aa)
GNA13G protein subunit alpha 13. (282 aa)
SYKTyrosine-protein kinase. (618 aa)
GUCY1A1Guanylate cyclase 1 soluble subunit alpha 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (690 aa)
RDH13Retinol dehydrogenase 13; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (328 aa)
FCGR2AUncharacterized protein. (276 aa)
PRKCIProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (583 aa)
PIK3R3Phosphoinositide-3-kinase regulatory subunit 3. (461 aa)
PLA2G4BPhospholipase A2. (781 aa)
PTGIRProstaglandin I2 receptor. (386 aa)
ACTBActin beta. (375 aa)
TLN2Talin 2. (2544 aa)
JMJD7Jumonji domain containing 7. (316 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (748 aa)
LOC105553738Uncharacterized protein. (160 aa)
RHOARas homolog family member A. (193 aa)
COL1A2Collagen type I alpha 2 chain. (1366 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1073 aa)
AKT1Non-specific serine/threonine protein kinase. (432 aa)
PPP1CCSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (355 aa)
RAP1BUncharacterized protein. (184 aa)
MAPK12Mitogen-activated protein kinase. (292 aa)
ENSMLEP00000027131Uncharacterized protein. (130 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1146 aa)
GNAI3G protein subunit alpha i3. (354 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
ADCY5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1064 aa)
LCP2Lymphocyte cytosolic protein 2. (533 aa)
ENSMLEP00000024790Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (294 aa)
VAMP8Vesicle associated membrane protein 8. (100 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1221 aa)
LOC105548340Uncharacterized protein. (246 aa)
ADCY1Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (338 aa)
MAPK1Mitogen-activated protein kinase. (343 aa)
MAPK11Mitogen-activated protein kinase. (224 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1089 aa)
PLA2G4CPhospholipase A2 group IVC. (469 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2675 aa)
LOC105548088Titin. (30818 aa)
ITGA2BIntegrin subunit alpha 2b; Belongs to the integrin alpha chain family. (1039 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
PIK3R6Phosphoinositide-3-kinase regulatory subunit 6. (754 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (364 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (352 aa)
COL1A1Collagen type I alpha 1 chain. (1464 aa)
GUCY1A2Guanylate cyclase 1 soluble subunit alpha 2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (631 aa)
LOC105540399Uncharacterized protein; Belongs to the actin family. (362 aa)
F2RCoagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family. (425 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
ORAI1ORAI calcium release-activated calcium modulator 1. (238 aa)
FGAFibrinogen alpha chain. (861 aa)
ADCY2Adenylate cyclase 2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (901 aa)
STIM1Stromal interaction molecule 1. (790 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (596 aa)
FYNTyrosine-protein kinase. (537 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (788 aa)
MYLKMyosin light chain kinase. (1912 aa)
PLA2G4APhospholipase A2. (749 aa)
NOS3Nitric oxide synthase; Produces nitric oxide (NO). (1155 aa)
MYLK3Myosin light chain kinase 3. (819 aa)
PRKG2cGMP-dependent protein kinase. (762 aa)
PPP1CBSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (322 aa)
ENSMLEP00000011903Uncharacterized protein. (183 aa)
GP6Glycoprotein VI platelet. (536 aa)
LOC105553882Uncharacterized protein. (356 aa)
LOC105542926Uncharacterized protein. (356 aa)
PIK3CGPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1082 aa)
MYLK2Myosin light chain kinase 2. (595 aa)
PTK6Tyrosine-protein kinase. (451 aa)
ROCK2Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1375 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2731 aa)
GNAQG protein subunit alpha q. (313 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1165 aa)
PIK3R5Phosphoinositide-3-kinase regulatory subunit 5. (881 aa)
ARHGEF1Rho guanine nucleotide exchange factor 1. (968 aa)
RAP1ARAP1A, member of RAS oncogene family. (184 aa)
PPP1CASerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (355 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1183 aa)
MYL12AMyosin light chain 12A. (177 aa)
ACTL7AActin like 7A; Belongs to the actin family. (435 aa)
ARHGEF12Rho guanine nucleotide exchange factor 12. (1544 aa)
P2RY1Purinergic receptor P2Y1; Belongs to the G-protein coupled receptor 1 family. (373 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2663 aa)
GNAI2G protein subunit alpha i2. (352 aa)
ACTRT1Actin related protein T1; Belongs to the actin family. (375 aa)
PTGS1Prostaglandin-endoperoxide synthase 1. (632 aa)
APBB1IPAmyloid beta precursor protein binding family B member 1 interacting protein. (547 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1251 aa)
RHOCRas homolog family member C. (193 aa)
P2RY12Purinergic receptor P2Y12. (342 aa)
MYL12BMyosin light chain 12B. (172 aa)
ENSMLEP00000004779Uncharacterized protein. (139 aa)
P2RX1P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (399 aa)
ITGA2Integrin subunit alpha 2; Belongs to the integrin alpha chain family. (1152 aa)
FGBFibrinogen beta chain. (491 aa)
GNASGNAS complex locus. (998 aa)
PRKG1cGMP-dependent protein kinase. (686 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1082 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa)
FCGR2BUncharacterized protein. (313 aa)
ENSMLEP00000003080Uncharacterized protein. (149 aa)
DHRSXDehydrogenase/reductase X-linked; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (293 aa)
ADCY4Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
ACTRT2Actin related protein T2; Belongs to the actin family. (377 aa)
ACTL7BActin like 7B; Belongs to the actin family. (415 aa)
PLA2G4FPhospholipase A2. (849 aa)
PLA2G4EPhospholipase A2. (869 aa)
COL3A1Collagen type III alpha 1 chain. (1466 aa)
PLA2G4DPhospholipase A2. (817 aa)
ZNF408Zinc finger protein 408. (719 aa)
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
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