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ENSMLEP00000001003 ENSMLEP00000001003 GRIA3 GRIA3 CAMK2D CAMK2D RASD1 RASD1 PRKG1 PRKG1 LOC105540811 LOC105540811 CALML3 CALML3 GNAS GNAS ADCYAP1R1 ADCYAP1R1 ADCY8 ADCY8 CACNA1H CACNA1H GNAI2 GNAI2 GNB3 GNB3 ENSMLEP00000007417 ENSMLEP00000007417 PLCB1 PLCB1 ADCY7 ADCY7 CAMK2B CAMK2B CAMK2G CAMK2G GNG2 GNG2 LOC105550079 LOC105550079 PLCB4 PLCB4 GNAQ GNAQ ITPR1 ITPR1 RYR2 RYR2 CALM1 CALM1 NOS1 NOS1 PRKG2 PRKG2 GRIA4 GRIA4 C1orf226 C1orf226 ADCY2 ADCY2 PVALEF PVALEF ADCY10 ADCY10 KCNJ9 KCNJ9 ENSMLEP00000018922 ENSMLEP00000018922 CALM2 CALM2 CREB1 CREB1 CACNA1D CACNA1D PER1 PER1 GNB1 GNB1 GUCY1A2 GUCY1A2 CALML4 CALML4 PRKACA PRKACA PRKCA PRKCA MAPK3 MAPK3 CACNA1G CACNA1G ITPR3 ITPR3 GNB5 GNB5 PLCB2 PLCB2 MAPK1 MAPK1 GNB2 GNB2 ADCY1 ADCY1 LOC105548340 LOC105548340 GRIN2D GRIN2D PRKCB PRKCB PRKCG PRKCG ENSMLEP00000024790 ENSMLEP00000024790 KCNJ3 KCNJ3 ADCY5 ADCY5 GRIA2 GRIA2 GNGT2 GNGT2 GNAI3 GNAI3 MTNR1A MTNR1A CACNA1C CACNA1C ADCY3 ADCY3 GRIN2C GRIN2C GRIA1 GRIA1 GRIN2A GRIN2A ENSMLEP00000028401 ENSMLEP00000028401 GNAO1 GNAO1 CACNA1I CACNA1I GNG12 GNG12 GNG5 GNG5 GNG3 GNG3 RYR1 RYR1 ARSI ARSI GNG4 GNG4 MTNR1B MTNR1B GUCY1A1 GUCY1A1 CAMK2A CAMK2A FOS FOS PRKACB PRKACB FBXO21 FBXO21 CALM3 CALM3 GUCY1B1 GUCY1B1 GNGT1 GNGT1 ADCYAP1 ADCYAP1 GNAI1 GNAI1 NOS1AP NOS1AP GNG8 GNG8 PER3 PER3 KCNJ5 KCNJ5 GNG13 GNG13 ADCY6 ADCY6 ENSMLEP00000038520 ENSMLEP00000038520 RYR3 RYR3 PLCB3 PLCB3 RPS6KA5 RPS6KA5 CALML6 CALML6 ADCY9 ADCY9 GNB4 GNB4 ADCY4 ADCY4 ENSMLEP00000002165 ENSMLEP00000002165 ENSMLEP00000001951 ENSMLEP00000001951 PER2 PER2 KCNJ6 KCNJ6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSMLEP00000001003CaM_bdg_C0 domain-containing protein. (124 aa)
GRIA3Glutamate ionotropic receptor AMPA type subunit 3. (894 aa)
CAMK2DCalcium/calmodulin dependent protein kinase II delta. (441 aa)
RASD1Uncharacterized protein. (122 aa)
PRKG1cGMP-dependent protein kinase. (686 aa)
LOC105540811Uncharacterized protein; Belongs to the calmodulin family. (128 aa)
CALML3Calmodulin like 3; Belongs to the calmodulin family. (149 aa)
GNASGNAS complex locus. (998 aa)
ADCYAP1R1ADCYAP receptor type I; Belongs to the G-protein coupled receptor 2 family. (523 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1251 aa)
CACNA1HCalcium voltage-gated channel subunit alpha1 H. (2170 aa)
GNAI2G protein subunit alpha i2. (352 aa)
GNB3G protein subunit beta 3. (340 aa)
ENSMLEP00000007417Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1183 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1082 aa)
CAMK2BCalcium/calmodulin dependent protein kinase II beta. (689 aa)
CAMK2GCalcium/calmodulin dependent protein kinase II gamma. (546 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (110 aa)
LOC105550079Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1165 aa)
GNAQG protein subunit alpha q. (313 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2731 aa)
RYR2Ryanodine receptor 2. (4862 aa)
CALM1Calmodulin 1; Belongs to the calmodulin family. (149 aa)
NOS1Nitric oxide synthase; Produces nitric oxide (NO). (1404 aa)
PRKG2cGMP-dependent protein kinase. (762 aa)
GRIA4Glutamate ionotropic receptor AMPA type subunit 4. (902 aa)
C1orf226Chromosome 1 open reading frame 226. (272 aa)
ADCY2Adenylate cyclase 2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (901 aa)
PVALEFParvalbumin like EF-hand containing. (133 aa)
ADCY10Adenylate cyclase 10. (1517 aa)
KCNJ9Potassium voltage-gated channel subfamily J member 9. (411 aa)
ENSMLEP00000018922ANF_receptor domain-containing protein. (356 aa)
CALM2Calmodulin 2. (149 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2181 aa)
PER1Period circadian regulator 1. (1292 aa)
GNB1G protein subunit beta 1. (340 aa)
GUCY1A2Guanylate cyclase 1 soluble subunit alpha 2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (631 aa)
CALML4Calmodulin like 4. (193 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (352 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (614 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (364 aa)
CACNA1GVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2360 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2675 aa)
GNB5G protein subunit beta 5. (357 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1089 aa)
MAPK1Mitogen-activated protein kinase. (343 aa)
GNB2G protein subunit beta 2. (340 aa)
ADCY1Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (338 aa)
LOC105548340Uncharacterized protein. (246 aa)
GRIN2DGlutamate ionotropic receptor NMDA type subunit 2D. (747 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (582 aa)
PRKCGProtein kinase C gamma; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (558 aa)
ENSMLEP00000024790Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (294 aa)
KCNJ3Potassium voltage-gated channel subfamily J member 3. (501 aa)
ADCY5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1064 aa)
GRIA2Glutamate ionotropic receptor AMPA type subunit 2. (883 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (88 aa)
GNAI3G protein subunit alpha i3. (354 aa)
MTNR1AMelatonin receptor 1A; Belongs to the G-protein coupled receptor 1 family. (328 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2169 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1146 aa)
GRIN2CGlutamate ionotropic receptor NMDA type subunit 2C; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (702 aa)
GRIA1Glutamate ionotropic receptor AMPA type subunit 1. (916 aa)
GRIN2AGlutamate ionotropic receptor NMDA type subunit 2A; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1422 aa)
ENSMLEP00000028401Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (65 aa)
GNAO1G protein subunit alpha o1. (354 aa)
CACNA1IVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2080 aa)
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
GNG5Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
RYR1Ryanodine receptor 1. (4628 aa)
ARSIArylsulfatase family member I. (568 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
MTNR1BMelatonin receptor 1B; Belongs to the G-protein coupled receptor 1 family. (362 aa)
GUCY1A1Guanylate cyclase 1 soluble subunit alpha 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (690 aa)
CAMK2ACalcium/calmodulin dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (489 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
FBXO21F-box protein 21. (537 aa)
CALM3Calmodulin 3. (149 aa)
GUCY1B1Guanylate cyclase 1 soluble subunit beta 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (554 aa)
GNGT1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
ADCYAP1Adenylate cyclase activating polypeptide 1. (176 aa)
GNAI1G protein subunit alpha i1. (314 aa)
NOS1APNitric oxide synthase 1 adaptor protein. (506 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
PER3Period circadian regulator 3. (1169 aa)
KCNJ5Potassium voltage-gated channel subfamily J member 5. (419 aa)
GNG13Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (67 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1168 aa)
ENSMLEP00000038520Uncharacterized protein; Belongs to the calmodulin family. (91 aa)
RYR3Ryanodine receptor 3. (4804 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1245 aa)
RPS6KA5Ribosomal protein S6 kinase. (801 aa)
CALML6Calmodulin like 6. (181 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa)
GNB4G protein subunit beta 4. (340 aa)
ADCY4Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
ENSMLEP00000002165Uncharacterized protein; Belongs to the calmodulin family. (95 aa)
ENSMLEP00000001951Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (60 aa)
PER2Period circadian regulator 2. (1254 aa)
KCNJ6Potassium voltage-gated channel subfamily J member 6. (423 aa)
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
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