76 items (Mandrillus leucophaeus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSMLEP00000004779	Uncharacterized protein. (139 aa)
	RPS6KA2	Ribosomal protein S6 kinase. (728 aa)
	CALML3	Calmodulin like 3; Belongs to the calmodulin family. (149 aa)
	LOC105540811	Uncharacterized protein; Belongs to the calmodulin family. (128 aa)
	PPP3CC	Serine/threonine-protein phosphatase. (438 aa)
	RPS6KA6	Ribosomal protein S6 kinase. (744 aa)
	ENSMLEP00000002165	Uncharacterized protein; Belongs to the calmodulin family. (95 aa)
	ENSMLEP00000001003	CaM_bdg_C0 domain-containing protein. (124 aa)
	CREBBP	CREB binding protein. (2423 aa)
	CAMK2D	Calcium/calmodulin dependent protein kinase II delta. (441 aa)
	GRIN2D	Glutamate ionotropic receptor NMDA type subunit 2D. (747 aa)
	ADCY1	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (338 aa)
	MAPK1	Mitogen-activated protein kinase. (343 aa)
	PPP3CB	Serine/threonine-protein phosphatase. (524 aa)
	PRKCB	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (582 aa)
	PRKCG	Protein kinase C gamma; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (558 aa)
	ENSMLEP00000024790	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (294 aa)
	ENSMLEP00000024805	Protein kinase domain-containing protein. (365 aa)
	GRIA2	Glutamate ionotropic receptor AMPA type subunit 2. (883 aa)
	GRM1	Glutamate metabotropic receptor 1. (961 aa)
	ARAF	A-Raf proto-oncogene, serine/threonine kinase. (604 aa)
	CACNA1C	Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2169 aa)
	GRIN2C	Glutamate ionotropic receptor NMDA type subunit 2C; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (702 aa)
	GRIA1	Glutamate ionotropic receptor AMPA type subunit 1. (916 aa)
	RAP1B	Uncharacterized protein. (184 aa)
	PPP1CC	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (355 aa)
	GRIN2A	Glutamate ionotropic receptor NMDA type subunit 2A; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1422 aa)
	PPP3R1	Uncharacterized protein. (189 aa)
	LOC105553738	Uncharacterized protein. (160 aa)
	CSDE1	Cold shock domain containing E1. (844 aa)
	NRAS	NRAS proto-oncogene, GTPase. (189 aa)
	ARSI	Arylsulfatase family member I. (568 aa)
	EP300	E1A binding protein p300. (2411 aa)
	CAMK2A	Calcium/calmodulin dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (489 aa)
	PRKACB	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
	CALM3	Calmodulin 3. (149 aa)
	BRAF	B-Raf proto-oncogene, serine/threonine kinase. (745 aa)
	RAPGEF3	Rap guanine nucleotide exchange factor 3. (925 aa)
	HRAS	HRas proto-oncogene, GTPase. (189 aa)
	PPP1R1A	Protein phosphatase 1 regulatory inhibitor subunit 1A. (143 aa)
	GRM5	Glutamate metabotropic receptor 5. (1039 aa)
	RPS6KA1	Ribosomal protein S6 kinase. (744 aa)
	ENSMLEP00000038520	Uncharacterized protein; Belongs to the calmodulin family. (91 aa)
	PLCB3	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1245 aa)
	CALML6	Calmodulin like 6. (181 aa)
	CALML4	Calmodulin like 4. (193 aa)
	PRKACA	Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (352 aa)
	PRKCA	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (614 aa)
	MAPK3	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (364 aa)
	CAMK4	Calcium/calmodulin dependent protein kinase IV; Belongs to the protein kinase superfamily. (473 aa)
	ITPR3	Inositol 1,4,5-trisphosphate receptor type 3. (2675 aa)
	PLCB2	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1089 aa)
	MAP2K1	Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
	RPS6KA3	Ribosomal protein S6 kinase. (742 aa)
	CALM2	Calmodulin 2. (149 aa)
	ENSMLEP00000018922	ANF_receptor domain-containing protein. (356 aa)
	PVALEF	Parvalbumin like EF-hand containing. (133 aa)
	MAP2K2	Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (389 aa)
	PPP1CB	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (322 aa)
	ENSMLEP00000012301	Protein kinase domain-containing protein. (294 aa)
	RAF1	Raf-1 proto-oncogene, serine/threonine kinase. (668 aa)
	CALM1	Calmodulin 1; Belongs to the calmodulin family. (149 aa)
	PPP3CA	Serine/threonine-protein phosphatase. (501 aa)
	ITPR1	Inositol 1,4,5-trisphosphate receptor type 1. (2731 aa)
	GNAQ	G protein subunit alpha q. (313 aa)
	PLCB4	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1165 aa)
	RAP1A	RAP1A, member of RAS oncogene family. (184 aa)
	KRAS	KRAS proto-oncogene, GTPase. (189 aa)
	PPP1CA	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (355 aa)
	CAMK2G	Calcium/calmodulin dependent protein kinase II gamma. (546 aa)
	CAMK2B	Calcium/calmodulin dependent protein kinase II beta. (689 aa)
	PLCB1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1183 aa)
	ERAS	ES cell expressed Ras. (233 aa)
	ITPR2	Inositol 1,4,5-trisphosphate receptor type 2. (2663 aa)
	ATF4	Activating transcription factor 4. (351 aa)
	ADCY8	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1251 aa)

Your Current Organism:

Mandrillus leucophaeus

NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADCY1	ADCY8	ENSMLEP00000023897	ENSMLEP00000005323	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.569
ADCY1	CALM1	ENSMLEP00000023897	ENSMLEP00000010731	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Calmodulin 1; Belongs to the calmodulin family.	0.626
ADCY1	CALM2	ENSMLEP00000023897	ENSMLEP00000019375	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Calmodulin 2.	0.626
ADCY1	CALML3	ENSMLEP00000023897	ENSMLEP00000003840	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Calmodulin like 3; Belongs to the calmodulin family.	0.566
ADCY1	CALML4	ENSMLEP00000023897	ENSMLEP00000020605	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Calmodulin like 4.	0.659
ADCY1	CALML6	ENSMLEP00000023897	ENSMLEP00000040866	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Calmodulin like 6.	0.675
ADCY1	CAMK2A	ENSMLEP00000023897	ENSMLEP00000032105	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Calcium/calmodulin dependent protein kinase II alpha; Belongs to the protein kinase superfamily.	0.591
ADCY1	CAMK2B	ENSMLEP00000023897	ENSMLEP00000008074	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Calcium/calmodulin dependent protein kinase II beta.	0.606
ADCY1	CAMK2D	ENSMLEP00000023897	ENSMLEP00000000279	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Calcium/calmodulin dependent protein kinase II delta.	0.591
ADCY1	CAMK2G	ENSMLEP00000023897	ENSMLEP00000008222	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Calcium/calmodulin dependent protein kinase II gamma.	0.577
ADCY1	CAMK4	ENSMLEP00000023897	ENSMLEP00000022089	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Calcium/calmodulin dependent protein kinase IV; Belongs to the protein kinase superfamily.	0.569
ADCY1	PRKACA	ENSMLEP00000023897	ENSMLEP00000020813	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily.	0.639
ADCY1	PRKACB	ENSMLEP00000023897	ENSMLEP00000032707	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily.	0.639
ADCY1	PRKCA	ENSMLEP00000023897	ENSMLEP00000020958	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.592
ADCY1	PRKCB	ENSMLEP00000023897	ENSMLEP00000024458	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.575
ADCY1	PRKCG	ENSMLEP00000023897	ENSMLEP00000024708	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Protein kinase C gamma; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.581
ADCY1	PVALEF	ENSMLEP00000023897	ENSMLEP00000018231	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Parvalbumin like EF-hand containing.	0.575
ADCY1	RAPGEF3	ENSMLEP00000023897	ENSMLEP00000035086	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Rap guanine nucleotide exchange factor 3.	0.628
ADCY8	ADCY1	ENSMLEP00000005323	ENSMLEP00000023897	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.569
ADCY8	CALM1	ENSMLEP00000005323	ENSMLEP00000010731	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calmodulin 1; Belongs to the calmodulin family.	0.806