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SLC25A1 SLC25A1 NAPA NAPA ATP6V0D1 ATP6V0D1 SLC1A2 SLC1A2 RAB3B RAB3B AP2B1 AP2B1 ATP6V1B2 ATP6V1B2 CLTB CLTB SLC1A1 SLC1A1 ATP6V0A4 ATP6V0A4 STX1A STX1A SLC6A1 SLC6A1 SLC6A7 SLC6A7 SNAP25 SNAP25 RAB3A RAB3A RIMS1 RIMS1 STX3 STX3 ATP6V1B1 ATP6V1B1 CACNA1B CACNA1B CACNA1A CACNA1A SLC17A8 SLC17A8 ATP6V1D ATP6V1D STX2 STX2 SLC18A1 SLC18A1 ATP6V0A2 ATP6V0A2 ENSMLEP00000027162 ENSMLEP00000027162 ATP6V1F ATP6V1F NAPB NAPB STXBP1 STXBP1 CPLX2 CPLX2 AP2M1 AP2M1 ENSMLEP00000025432 ENSMLEP00000025432 ATP6V1G1 ATP6V1G1 ATP6V1E1 ATP6V1E1 ATP6V1G3 ATP6V1G3 SLC17A6 SLC17A6 ATP6V0C ATP6V0C STX1B STX1B CPLX1 CPLX1 ENSMLEP00000022700 ENSMLEP00000022700 UNC13B UNC13B CLTA CLTA SLC6A3 SLC6A3 CPLX3 CPLX3 UNC13A UNC13A AP2S1 AP2S1 ATP6V0B ATP6V0B SLC17A7 SLC17A7 ATP6V1G2 ATP6V1G2 SLC18A2 SLC18A2 ATP6V1A ATP6V1A ENSMLEP00000017851 ENSMLEP00000017851 UNC13C UNC13C SLC32A1 SLC32A1 DNM1 DNM1 CLTCL1 CLTCL1 LOC105533912 LOC105533912 DNM2 DNM2 ATP6V0D2 ATP6V0D2 SLC6A5 SLC6A5 CPLX4 CPLX4 CLTC CLTC ENSMLEP00000013122 ENSMLEP00000013122 ATP6V0E1 ATP6V0E1 RAB3C RAB3C AP2A2 AP2A2 ATP6V0A1 ATP6V0A1 SYT1 SYT1 SLC6A12 SLC6A12 DUXA DUXA SLC6A13 SLC6A13 NSF NSF SLC18A3 SLC18A3 SLC1A3 SLC1A3 ATP6V1C1 ATP6V1C1 SLC1A7 SLC1A7 SYT2 SYT2 ATP6V1C2 ATP6V1C2 SLC6A2 SLC6A2 SLC6A11 SLC6A11 ATP6V1E2 ATP6V1E2 ATP6V1H ATP6V1H SLC6A9 SLC6A9 TCIRG1 TCIRG1 DNM3 DNM3 ENSMLEP00000002144 ENSMLEP00000002144 VAMP2 VAMP2 SLC6A4 SLC6A4 AP2A1 AP2A1 SLC1A6 SLC1A6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SLC25A1Solute carrier family 25 member 1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (208 aa)
NAPANSF attachment protein alpha. (295 aa)
ATP6V0D1V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family. (392 aa)
SLC1A2Amino acid transporter. (574 aa)
RAB3BRAB3B, member RAS oncogene family. (228 aa)
AP2B1AP complex subunit beta. (942 aa)
ATP6V1B2Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (498 aa)
CLTBClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (203 aa)
SLC1A1Solute carrier family 1 member 1. (524 aa)
ATP6V0A4V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (750 aa)
STX1ASyntaxin 1A; Belongs to the syntaxin family. (288 aa)
SLC6A1Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (599 aa)
SLC6A7Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (666 aa)
SNAP25Synaptosomal-associated protein; Belongs to the SNAP-25 family. (206 aa)
RAB3ARAB3A, member RAS oncogene family. (220 aa)
RIMS1Regulating synaptic membrane exocytosis 1. (1692 aa)
STX3Syntaxin 3; Belongs to the syntaxin family. (290 aa)
ATP6V1B1Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (513 aa)
CACNA1BCalcium voltage-gated channel subunit alpha1 B. (2001 aa)
CACNA1ACalcium voltage-gated channel subunit alpha1 A. (1985 aa)
SLC17A8Solute carrier family 17 member 8. (589 aa)
ATP6V1DATPase H+ transporting V1 subunit D. (249 aa)
STX2Syntaxin 2; Belongs to the syntaxin family. (278 aa)
SLC18A1Solute carrier family 18 member A1. (525 aa)
ATP6V0A2V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (822 aa)
ENSMLEP00000027162Uncharacterized protein. (195 aa)
ATP6V1FV-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (147 aa)
NAPBNSF attachment protein beta. (269 aa)
STXBP1Syntaxin binding protein 1; Belongs to the STXBP/unc-18/SEC1 family. (597 aa)
CPLX2Complexin 2. (134 aa)
AP2M1AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...] (458 aa)
ENSMLEP00000025432B2-adapt-app_C domain-containing protein. (224 aa)
ATP6V1G1V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (118 aa)
ATP6V1E1Uncharacterized protein. (204 aa)
ATP6V1G3V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (124 aa)
SLC17A6Solute carrier family 17 member 6. (582 aa)
ATP6V0CV-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (128 aa)
STX1BSyntaxin 1B; Belongs to the syntaxin family. (245 aa)
CPLX1Complexin 1. (134 aa)
ENSMLEP00000022700Uncharacterized protein. (104 aa)
UNC13BUncharacterized protein. (4338 aa)
CLTAClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (248 aa)
SLC6A3Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (620 aa)
CPLX3Complexin 3. (158 aa)
UNC13AUnc-13 homolog A. (1520 aa)
AP2S1AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (158 aa)
ATP6V0BATPase H+ transporting V0 subunit b; Belongs to the V-ATPase proteolipid subunit family. (255 aa)
SLC17A7Solute carrier family 17 member 7. (560 aa)
ATP6V1G2V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (158 aa)
SLC18A2Solute carrier family 18 member A2. (517 aa)
ATP6V1AATPase H+ transporting V1 subunit A. (617 aa)
ENSMLEP00000017851V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (107 aa)
UNC13CUnc-13 homolog C. (2186 aa)
SLC32A1Solute carrier family 32 member 1. (525 aa)
DNM1Dynamin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (797 aa)
CLTCL1Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1572 aa)
LOC105533912Uncharacterized protein. (218 aa)
DNM2Dynamin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (810 aa)
ATP6V0D2ATPase H+ transporting V0 subunit d2. (306 aa)
SLC6A5Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (797 aa)
CPLX4Complexin 4. (160 aa)
CLTCClathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1679 aa)
ENSMLEP00000013122Uncharacterized protein. (179 aa)
ATP6V0E1V-type proton ATPase subunit; Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (81 aa)
RAB3CRAB3C, member RAS oncogene family. (165 aa)
AP2A2AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (939 aa)
ATP6V0A1V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (775 aa)
SYT1Synaptotagmin 1. (422 aa)
SLC6A12Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (530 aa)
DUXADouble homeobox A. (204 aa)
SLC6A13Solute carrier family 6 member 13. (594 aa)
NSFN-ethylmaleimide sensitive factor, vesicle fusing ATPase. (740 aa)
SLC18A3Solute carrier family 18 member A3. (518 aa)
SLC1A3Amino acid transporter. (542 aa)
ATP6V1C1V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (382 aa)
SLC1A7Amino acid transporter. (619 aa)
SYT2Synaptotagmin 2. (419 aa)
ATP6V1C2V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (417 aa)
SLC6A2Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (628 aa)
SLC6A11Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (604 aa)
ATP6V1E2ATPase H+ transporting V1 subunit E2. (226 aa)
ATP6V1HV-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. (483 aa)
SLC6A9Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (706 aa)
TCIRG1V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (830 aa)
DNM3Dynamin 3; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (864 aa)
ENSMLEP00000002144V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (142 aa)
VAMP2V-SNARE coiled-coil homology domain-containing protein. (118 aa)
SLC6A4Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (630 aa)
AP2A1AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (912 aa)
SLC1A6Amino acid transporter. (564 aa)
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
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