STRINGSTRING
CALML6 CALML6 CAMK2D CAMK2D GRIA3 GRIA3 DDC DDC MAOA MAOA KCNJ6 KCNJ6 PPP2R5E PPP2R5E DRD5 DRD5 ENSMLEP00000001951 ENSMLEP00000001951 KIF5B KIF5B ENSMLEP00000002165 ENSMLEP00000002165 PPP2R2D PPP2R2D PPP1R1B PPP1R1B CREB3 CREB3 GNB4 GNB4 PPP3CC PPP3CC LOC105540811 LOC105540811 CALML3 CALML3 GNAS GNAS PPP2R5C PPP2R5C ATF4 ATF4 GNAI2 GNAI2 ITPR2 ITPR2 GNB3 GNB3 CREB3L3 CREB3L3 MAPK10 MAPK10 PPP2R2C PPP2R2C LOC105551588 LOC105551588 ENSMLEP00000007417 ENSMLEP00000007417 PLCB1 PLCB1 MAPK9 MAPK9 CAMK2B CAMK2B PPP2R5A PPP2R5A CAMK2G CAMK2G DRD1 DRD1 PPP1CA PPP1CA GNG2 GNG2 LOC105550079 LOC105550079 PLCB4 PLCB4 GNAQ GNAQ ITPR1 ITPR1 PPP2R2B PPP2R2B PPP3CA PPP3CA CALM1 CALM1 PPP2R3A PPP2R3A PPP2R1A PPP2R1A DRD3 DRD3 SCN1A SCN1A PPP1CB PPP1CB ARRB2 ARRB2 CREB3L4 CREB3L4 GRIA4 GRIA4 PPP2CA PPP2CA COMT COMT MAPK8 MAPK8 CLOCK CLOCK KIF5A KIF5A ENSMLEP00000018038 ENSMLEP00000018038 PVALEF PVALEF KCNJ9 KCNJ9 SLC18A2 SLC18A2 ATF6B ATF6B CALM2 CALM2 CREB1 CREB1 CACNA1D CACNA1D TH TH GNB1 GNB1 CALML4 CALML4 PRKACA PRKACA PRKCA PRKCA PPP2CB PPP2CB SLC6A3 SLC6A3 AKT2 AKT2 ITPR3 ITPR3 PPP2R5D PPP2R5D ATF2 ATF2 GNB5 GNB5 PLCB2 PLCB2 MAPK11 MAPK11 GNB2 GNB2 ENSMLEP00000023964 ENSMLEP00000023964 LOC105548340 LOC105548340 PPP3CB PPP3CB PRKCB PRKCB GSK3B GSK3B PRKCG PRKCG KCNJ3 KCNJ3 ADCY5 ADCY5 GRIA2 GRIA2 ARR3 ARR3 GNGT2 GNGT2 LOC105549238 LOC105549238 GNAI3 GNAI3 CACNA1C CACNA1C MAPK12 MAPK12 GRIA1 GRIA1 PPP1CC PPP1CC AKT1 AKT1 GRIN2A GRIN2A ENSMLEP00000028401 ENSMLEP00000028401 GNAO1 GNAO1 GNG12 GNG12 SLC18A1 SLC18A1 KIF5C KIF5C ARRB1 ARRB1 MAOB MAOB GNG5 GNG5 CREB5 CREB5 GNG3 GNG3 ARSI ARSI GNG4 GNG4 ARNTL ARNTL CAMK2A CAMK2A CACNA1A CACNA1A CACNA1B CACNA1B FOS FOS MAPK13 MAPK13 PRKACB PRKACB CALM3 CALM3 PPP2R2A PPP2R2A GNGT1 GNGT1 GNAI1 GNAI1 PPP2R5B PPP2R5B GNG8 GNG8 KCNJ5 KCNJ5 CALY CALY AKT3 AKT3 GNG13 GNG13 GNAL GNAL CREB3L2 CREB3L2 MAPK14 MAPK14 ENSMLEP00000038520 ENSMLEP00000038520 PPP2R1B PPP2R1B PLCB3 PLCB3 DRD2 DRD2 CREB3L1 CREB3L1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CALML6Calmodulin like 6. (181 aa)
CAMK2DCalcium/calmodulin dependent protein kinase II delta. (441 aa)
GRIA3Glutamate ionotropic receptor AMPA type subunit 3. (894 aa)
DDCDopa decarboxylase. (480 aa)
MAOAAmine oxidase. (527 aa)
KCNJ6Potassium voltage-gated channel subfamily J member 6. (423 aa)
PPP2R5ESerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (468 aa)
DRD5Dopamine receptor D5; Belongs to the G-protein coupled receptor 1 family. (478 aa)
ENSMLEP00000001951Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (60 aa)
KIF5BKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (958 aa)
ENSMLEP00000002165Uncharacterized protein; Belongs to the calmodulin family. (95 aa)
PPP2R2DSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (466 aa)
PPP1R1BProtein phosphatase 1 regulatory inhibitor subunit 1B. (204 aa)
CREB3cAMP responsive element binding protein 3. (372 aa)
GNB4G protein subunit beta 4. (340 aa)
PPP3CCSerine/threonine-protein phosphatase. (438 aa)
LOC105540811Uncharacterized protein; Belongs to the calmodulin family. (128 aa)
CALML3Calmodulin like 3; Belongs to the calmodulin family. (149 aa)
GNASGNAS complex locus. (998 aa)
PPP2R5CSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (580 aa)
ATF4Activating transcription factor 4. (351 aa)
GNAI2G protein subunit alpha i2. (352 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2663 aa)
GNB3G protein subunit beta 3. (340 aa)
CREB3L3cAMP responsive element binding protein 3 like 3. (321 aa)
MAPK10Mitogen-activated protein kinase. (477 aa)
PPP2R2CSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (447 aa)
LOC105551588Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (455 aa)
ENSMLEP00000007417Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1183 aa)
MAPK9Mitogen-activated protein kinase. (395 aa)
CAMK2BCalcium/calmodulin dependent protein kinase II beta. (689 aa)
PPP2R5ASerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (525 aa)
CAMK2GCalcium/calmodulin dependent protein kinase II gamma. (546 aa)
DRD1Dopamine receptor D1; Belongs to the G-protein coupled receptor 1 family. (446 aa)
PPP1CASerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (355 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (110 aa)
LOC105550079Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1165 aa)
GNAQG protein subunit alpha q. (313 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2731 aa)
PPP2R2BSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (509 aa)
PPP3CASerine/threonine-protein phosphatase. (501 aa)
CALM1Calmodulin 1; Belongs to the calmodulin family. (149 aa)
PPP2R3AProtein phosphatase 2 regulatory subunit B''alpha. (1150 aa)
PPP2R1AProtein phosphatase 2 scaffold subunit Aalpha. (589 aa)
DRD3Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family. (400 aa)
SCN1ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1912 aa)
PPP1CBSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (322 aa)
ARRB2Arrestin beta 2. (478 aa)
CREB3L4cAMP responsive element binding protein 3 like 4. (422 aa)
GRIA4Glutamate ionotropic receptor AMPA type subunit 4. (902 aa)
PPP2CASerine/threonine-protein phosphatase. (275 aa)
COMTCatechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. (221 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
CLOCKClock circadian regulator. (847 aa)
KIF5AKinesin family member 5A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1032 aa)
ENSMLEP00000018038Uncharacterized protein. (427 aa)
PVALEFParvalbumin like EF-hand containing. (133 aa)
KCNJ9Potassium voltage-gated channel subfamily J member 9. (411 aa)
SLC18A2Solute carrier family 18 member A2. (517 aa)
ATF6BActivating transcription factor 6 beta. (711 aa)
CALM2Calmodulin 2. (149 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2181 aa)
THTyrosine hydroxylase. (549 aa)
GNB1G protein subunit beta 1. (340 aa)
CALML4Calmodulin like 4. (193 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (352 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (614 aa)
PPP2CBSerine/threonine-protein phosphatase. (275 aa)
SLC6A3Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (620 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2675 aa)
PPP2R5DSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (605 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
GNB5G protein subunit beta 5. (357 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1089 aa)
MAPK11Mitogen-activated protein kinase. (224 aa)
GNB2G protein subunit beta 2. (340 aa)
ENSMLEP00000023964Uncharacterized protein. (190 aa)
LOC105548340Uncharacterized protein. (246 aa)
PPP3CBSerine/threonine-protein phosphatase. (524 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (582 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (478 aa)
PRKCGProtein kinase C gamma; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (558 aa)
KCNJ3Potassium voltage-gated channel subfamily J member 3. (501 aa)
ADCY5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1064 aa)
GRIA2Glutamate ionotropic receptor AMPA type subunit 2. (883 aa)
ARR3Arrestin 3. (389 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (88 aa)
LOC105549238Uncharacterized protein. (293 aa)
GNAI3G protein subunit alpha i3. (354 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2169 aa)
MAPK12Mitogen-activated protein kinase. (292 aa)
GRIA1Glutamate ionotropic receptor AMPA type subunit 1. (916 aa)
PPP1CCSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (355 aa)
AKT1Non-specific serine/threonine protein kinase. (432 aa)
GRIN2AGlutamate ionotropic receptor NMDA type subunit 2A; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1422 aa)
ENSMLEP00000028401Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (65 aa)
GNAO1G protein subunit alpha o1. (354 aa)
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
SLC18A1Solute carrier family 18 member A1. (525 aa)
KIF5CKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (917 aa)
ARRB1Arrestin beta 1. (417 aa)
MAOBAmine oxidase. (520 aa)
GNG5Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
CREB5Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription. (508 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
ARSIArylsulfatase family member I. (568 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
ARNTLAryl hydrocarbon receptor nuclear translocator like. (628 aa)
CAMK2ACalcium/calmodulin dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (489 aa)
CACNA1ACalcium voltage-gated channel subunit alpha1 A. (1985 aa)
CACNA1BCalcium voltage-gated channel subunit alpha1 B. (2001 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
MAPK13Mitogen-activated protein kinase. (397 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
CALM3Calmodulin 3. (149 aa)
PPP2R2ASerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (457 aa)
GNGT1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
GNAI1G protein subunit alpha i1. (314 aa)
PPP2R5BSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (502 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
KCNJ5Potassium voltage-gated channel subfamily J member 5. (419 aa)
CALYCalcyon neuron specific vesicular protein. (220 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
GNG13Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (67 aa)
GNALG protein subunit alpha L. (309 aa)
CREB3L2cAMP responsive element binding protein 3 like 2. (520 aa)
MAPK14Mitogen-activated protein kinase. (350 aa)
ENSMLEP00000038520Uncharacterized protein; Belongs to the calmodulin family. (91 aa)
PPP2R1BProtein phosphatase 2 scaffold subunit Abeta. (637 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1245 aa)
DRD2Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (443 aa)
CREB3L1cAMP responsive element binding protein 3 like 1. (466 aa)
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
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