STRINGSTRING
MAP2K6 MAP2K6 CYP4B1 CYP4B1 PPP1CB PPP1CB PTGER4 PTGER4 MAP2K3 MAP2K3 ENSMLEP00000012041 ENSMLEP00000012041 CALM1 CALM1 ITPR1 ITPR1 IL1RAP IL1RAP GNAQ GNAQ ENSMLEP00000009479 ENSMLEP00000009479 PLCB4 PLCB4 CYP2J2 CYP2J2 LOC105536685 LOC105536685 PPP1CA PPP1CA CAMK2G CAMK2G HTR2A HTR2A CAMK2B CAMK2B ASIC1 ASIC1 MAPK9 MAPK9 PLCB1 PLCB1 HRH1 HRH1 MAPK10 MAPK10 ITPR2 ITPR2 IGF1 IGF1 HTR2B HTR2B ADCY8 ADCY8 TRPM8 TRPM8 GNAS GNAS CALML3 CALML3 LOC105540811 LOC105540811 ADCY7 ADCY7 ADCY9 ADCY9 KNG1 KNG1 ALOX12 ALOX12 P2RY2 P2RY2 ADCY4 ADCY4 BDKRB1 BDKRB1 ENSMLEP00000002165 ENSMLEP00000002165 PLA2G4F PLA2G4F PLA2G4E PLA2G4E ASIC3 ASIC3 PIK3R2 PIK3R2 AADAC AADAC CAMK2D CAMK2D CALML6 CALML6 PLA2G4D PLA2G4D LOC105553718 LOC105553718 PLCB3 PLCB3 ENSMLEP00000038520 ENSMLEP00000038520 MAPK14 MAPK14 ADCY6 ADCY6 NGF NGF PRKCH PRKCH SRC SRC PLA2G6 PLA2G6 PRKCD PRKCD PIK3R1 PIK3R1 LOC105553702 LOC105553702 CALM3 CALM3 PRKACB PRKACB MAPK13 MAPK13 BDKRB2 BDKRB2 CAMK2A CAMK2A PIK3R3 PIK3R3 ARSI ARSI PLA2G4B PLA2G4B NTRK1 NTRK1 ASIC5 ASIC5 JMJD7 JMJD7 PLCG1 PLCG1 PIK3CB PIK3CB PPP1CC PPP1CC MAPK12 MAPK12 ADCY3 ADCY3 ASIC4 ASIC4 TRPA1 TRPA1 PIK3CD PIK3CD ADCY5 ADCY5 ENSMLEP00000024867 ENSMLEP00000024867 ENSMLEP00000024790 ENSMLEP00000024790 IL1B IL1B PRKCG PRKCG PRKCB PRKCB PLCG2 PLCG2 LOC105548340 LOC105548340 ADCY1 ADCY1 AADACL2 AADACL2 TRPV4 TRPV4 MAPK11 MAPK11 PLCB2 PLCB2 PLA2G4C PLA2G4C ITPR3 ITPR3 TRPV2 TRPV2 PRKCA PRKCA PRKACA PRKACA CALML4 CALML4 HTR2C HTR2C PIK3CA PIK3CA CALM2 CALM2 TRPV3 TRPV3 TRPV1 TRPV1 ENSMLEP00000018955 ENSMLEP00000018955 CYP2W1 CYP2W1 PVALEF PVALEF PTGER2 PTGER2 ADCY2 ADCY2 IL1R1 IL1R1 MAPK8 MAPK8 PRKCE PRKCE PRKCQ PRKCQ PLA2G4A PLA2G4A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MAP2K6Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (335 aa)
CYP4B1Cytochrome P450 family 4 subfamily B member 1; Belongs to the cytochrome P450 family. (326 aa)
PPP1CBSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (322 aa)
PTGER4Prostaglandin E receptor 4; Belongs to the G-protein coupled receptor 1 family. (470 aa)
MAP2K3Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (347 aa)
ENSMLEP00000012041C2 domain-containing protein. (121 aa)
CALM1Calmodulin 1; Belongs to the calmodulin family. (149 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2731 aa)
IL1RAPInterleukin 1 receptor accessory protein. (687 aa)
GNAQG protein subunit alpha q. (313 aa)
ENSMLEP00000009479Uncharacterized protein. (347 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1165 aa)
CYP2J2Cytochrome P450 family 2 subfamily J member 2; Belongs to the cytochrome P450 family. (502 aa)
LOC105536685Uncharacterized protein. (188 aa)
PPP1CASerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (355 aa)
CAMK2GCalcium/calmodulin dependent protein kinase II gamma. (546 aa)
HTR2A5-hydroxytryptamine receptor 2A. (471 aa)
CAMK2BCalcium/calmodulin dependent protein kinase II beta. (689 aa)
ASIC1Acid sensing ion channel subunit 1; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (574 aa)
MAPK9Mitogen-activated protein kinase. (395 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1183 aa)
HRH1Histamine receptor H1; Belongs to the G-protein coupled receptor 1 family. (487 aa)
MAPK10Mitogen-activated protein kinase. (477 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2663 aa)
IGF1Insulin like growth factor 1. (159 aa)
HTR2B5-hydroxytryptamine receptor 2B. (481 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1251 aa)
TRPM8Transient receptor potential cation channel subfamily M member 8. (1104 aa)
GNASGNAS complex locus. (998 aa)
CALML3Calmodulin like 3; Belongs to the calmodulin family. (149 aa)
LOC105540811Uncharacterized protein; Belongs to the calmodulin family. (128 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1082 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa)
KNG1Kininogen 1. (644 aa)
ALOX12Arachidonate 12-lipoxygenase, 12S type. (618 aa)
P2RY2Purinergic receptor P2Y2; Belongs to the G-protein coupled receptor 1 family. (377 aa)
ADCY4Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
BDKRB1Bradykinin receptor B1. (282 aa)
ENSMLEP00000002165Uncharacterized protein; Belongs to the calmodulin family. (95 aa)
PLA2G4FPhospholipase A2. (849 aa)
PLA2G4EPhospholipase A2. (869 aa)
ASIC3Acid sensing ion channel subunit 3; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (547 aa)
PIK3R2Uncharacterized protein. (587 aa)
AADACArylacetamide deacetylase. (399 aa)
CAMK2DCalcium/calmodulin dependent protein kinase II delta. (441 aa)
CALML6Calmodulin like 6. (181 aa)
PLA2G4DPhospholipase A2. (817 aa)
LOC105553718Uncharacterized protein; Belongs to the cytochrome P450 family. (489 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1245 aa)
ENSMLEP00000038520Uncharacterized protein; Belongs to the calmodulin family. (91 aa)
MAPK14Mitogen-activated protein kinase. (350 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1168 aa)
NGFNerve growth factor; Belongs to the NGF-beta family. (123 aa)
PRKCHProtein kinase C eta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that is involved in the regulation of cell differentiation in keratinocytes and pre-B cell receptor, mediates regulation of epithelial tight junction integrity and foam cell formation, and is required for glioblastoma proliferation and apoptosis prevention in MCF-7 cells. In keratinocytes, binds and activates the tyrosine kinase FYN, which in turn blocks epidermal growth factor receptor (EGFR) signaling and leads to keratinocyte growth arrest and differentia [...] (683 aa)
SRCTyrosine-protein kinase. (542 aa)
PLA2G6Phospholipase A2 group VI. (806 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
LOC105553702Uncharacterized protein; Belongs to the cytochrome P450 family. (489 aa)
CALM3Calmodulin 3. (149 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
MAPK13Mitogen-activated protein kinase. (397 aa)
BDKRB2Bradykinin receptor B2; Belongs to the G-protein coupled receptor 1 family. (391 aa)
CAMK2ACalcium/calmodulin dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (489 aa)
PIK3R3Phosphoinositide-3-kinase regulatory subunit 3. (461 aa)
ARSIArylsulfatase family member I. (568 aa)
PLA2G4BPhospholipase A2. (781 aa)
NTRK1Tyrosine-protein kinase receptor. (796 aa)
ASIC5Acid sensing ion channel subunit family member 5; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (505 aa)
JMJD7Jumonji domain containing 7. (316 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1276 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1073 aa)
PPP1CCSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (355 aa)
MAPK12Mitogen-activated protein kinase. (292 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1146 aa)
ASIC4Acid sensing ion channel subunit family member 4; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (666 aa)
TRPA1Transient receptor potential cation channel subfamily A member 1; Belongs to the transient receptor (TC 1.A.4) family. (1119 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
ADCY5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1064 aa)
ENSMLEP00000024867Uncharacterized protein; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (196 aa)
ENSMLEP00000024790Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (294 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (268 aa)
PRKCGProtein kinase C gamma; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (558 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (582 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1221 aa)
LOC105548340Uncharacterized protein. (246 aa)
ADCY1Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (338 aa)
AADACL2Arylacetamide deacetylase like 2. (401 aa)
TRPV4Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (871 aa)
MAPK11Mitogen-activated protein kinase. (224 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1089 aa)
PLA2G4CPhospholipase A2 group IVC. (469 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2675 aa)
TRPV2Transient receptor potential cation channel subfamily V member 2; Belongs to the transient receptor (TC 1.A.4) family. (764 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (614 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (352 aa)
CALML4Calmodulin like 4. (193 aa)
HTR2C5-hydroxytryptamine receptor 2C. (458 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
CALM2Calmodulin 2. (149 aa)
TRPV3Transient receptor potential cation channel subfamily V member 3; Belongs to the transient receptor (TC 1.A.4) family. (794 aa)
TRPV1Transient receptor potential cation channel subfamily V member 1; Belongs to the transient receptor (TC 1.A.4) family. (850 aa)
ENSMLEP00000018955Uncharacterized protein. (413 aa)
CYP2W1Cytochrome P450 family 2 subfamily W member 1; Belongs to the cytochrome P450 family. (462 aa)
PVALEFParvalbumin like EF-hand containing. (133 aa)
PTGER2Prostaglandin E receptor 2; Belongs to the G-protein coupled receptor 1 family. (358 aa)
ADCY2Adenylate cyclase 2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (901 aa)
IL1R1Interleukin 1 receptor type 1. (569 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
PRKCEProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (620 aa)
PRKCQProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (706 aa)
PLA2G4APhospholipase A2. (749 aa)
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
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