STRINGSTRING
ENSMLEP00000029948 ENSMLEP00000029948 ENSMLEP00000008990 ENSMLEP00000008990 PRKAR2A PRKAR2A NRAS NRAS EFCAB13 EFCAB13 PPP1R14B PPP1R14B GCK GCK PIK3R3 PIK3R3 PRKCI PRKCI EFCAB3 EFCAB3 SREBF1 SREBF1 BUD23 BUD23 RPTOR RPTOR ENSMLEP00000031736 ENSMLEP00000031736 CRYBB3 CRYBB3 RPS6 RPS6 PRKAR2B PRKAR2B PRKACB PRKACB PHKG2 PHKG2 RPS6KB2 RPS6KB2 IRS4 IRS4 RHEB RHEB PPP1R3C PPP1R3C CALM1 CALM1 IRS1 IRS1 PRKAR1B PRKAR1B PHKA2 PHKA2 SLC2A4 SLC2A4 RAF1 RAF1 CALML6 CALML6 SH2B1 SH2B1 G6PC G6PC ENSMLEP00000040499 ENSMLEP00000040499 PPP1R3A PPP1R3A PTPRF PTPRF PDPK1 PDPK1 CALM3 CALM3 PRKAG1 PRKAG1 KIAA1671 KIAA1671 PRKAB2 PRKAB2 PIK3R1 PIK3R1 CBLB CBLB PRKAA1 PRKAA1 BRAF BRAF PTPRD PTPRD RRAD RRAD SHC1 SHC1 HRAS HRAS PCK2 PCK2 SHC2 SHC2 AKT3 AKT3 ENSMLEP00000037200 ENSMLEP00000037200 RHOQ RHOQ G6PC2 G6PC2 RHEBL1 RHEBL1 MKNK1 MKNK1 ENSMLEP00000038520 ENSMLEP00000038520 PYGL PYGL PCK1 PCK1 PDE3B PDE3B SREBF2 SREBF2 HK1 HK1 ENSMLEP00000012301 ENSMLEP00000012301 BMT2 BMT2 PPP1CB PPP1CB FLOT2 FLOT2 GEM GEM SHC4 SHC4 FLOT1 FLOT1 MAP2K2 MAP2K2 ENSMLEP00000015404 ENSMLEP00000015404 HK3 HK3 MAPK8 MAPK8 FBP1 FBP1 KRAS KRAS PPP1CA PPP1CA ELK1 ELK1 PRKAG3 PRKAG3 ACACA ACACA ALKBH4 ALKBH4 MAPK9 MAPK9 RPS6KB1 RPS6KB1 FASN FASN PPP1R3D PPP1R3D ERAS ERAS SOCS2 SOCS2 MAPK10 MAPK10 GYS1 GYS1 PTPN1 PTPN1 REM1 REM1 PRKAB1 PRKAB1 MTOR MTOR MYO9A MYO9A HKDC1 HKDC1 EIF4E EIF4E CRK CRK TBCA TBCA ENSMLEP00000004236 ENSMLEP00000004236 CALML3 CALML3 ENSMLEP00000003823 ENSMLEP00000003823 LOC105540811 LOC105540811 PRKAA2 PRKAA2 BAD BAD HK2 HK2 EXOC7 EXOC7 ENSMLEP00000002280 ENSMLEP00000002280 ENSMLEP00000002165 ENSMLEP00000002165 INPPL1 INPPL1 ELK3 ELK3 PPP1R3B PPP1R3B PIK3R2 PIK3R2 INPP5A INPP5A SHC3 SHC3 PTPRS PTPRS EIF4EBP1 EIF4EBP1 SOCS4 SOCS4 PRKAR1A PRKAR1A CEP152 CEP152 INS INS ENSMLEP00000016272 ENSMLEP00000016272 SORBS2 SORBS2 PRKCZ PRKCZ FBP2 FBP2 INSR INSR IKBKB IKBKB GRB2 GRB2 PVALEF PVALEF GYS2 GYS2 PPP1R3F PPP1R3F PYGM PYGM CALM2 CALM2 CRKL CRKL PIK3CA PIK3CA MAP2K1 MAP2K1 PPARGC1A PPARGC1A MKNK2 MKNK2 MYO9B MYO9B SH2B2 SH2B2 G6PC3 G6PC3 CALML4 CALML4 PRKACA PRKACA TMEM145 TMEM145 MAPK3 MAPK3 RAPGEF1 RAPGEF1 ENSMLEP00000021430 ENSMLEP00000021430 SOS1 SOS1 AKT2 AKT2 SOS2 SOS2 PYGB PYGB PKLR PKLR PHKA1 PHKA1 MAPK1 MAPK1 PHKB PHKB CBL CBL CRYGN CRYGN GSK3B GSK3B ENSMLEP00000024805 ENSMLEP00000024805 EIF4E2 EIF4E2 ENSMLEP00000025175 ENSMLEP00000025175 SORBS1 SORBS1 TSC1 TSC1 ARAF ARAF PIK3CD PIK3CD EIF4E1B EIF4E1B LIPE LIPE TRIP10 TRIP10 PRKAG2 PRKAG2 PHKG1 PHKG1 ENSMLEP00000027485 ENSMLEP00000027485 PPP1CC PPP1CC AKT1 AKT1 PIK3CB PIK3CB SORBS3 SORBS3 CSDE1 CSDE1 LOC105549202 LOC105549202 TSC2 TSC2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSMLEP00000029948EF-hand domain-containing protein; Belongs to the calmodulin family. (73 aa)
ENSMLEP00000008990Uncharacterized protein. (858 aa)
PRKAR2AUncharacterized protein. (211 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
EFCAB13EF-hand calcium binding domain 13. (973 aa)
PPP1R14BUncharacterized protein. (127 aa)
GCKPhosphotransferase. (466 aa)
PIK3R3Phosphoinositide-3-kinase regulatory subunit 3. (461 aa)
PRKCIProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (583 aa)
EFCAB3EF-hand calcium binding domain 3. (488 aa)
SREBF1Sterol regulatory element binding transcription factor 1. (1124 aa)
BUD23BUD23 rRNA methyltransferase and ribosome maturation factor. (297 aa)
RPTORRegulatory associated protein of MTOR complex 1. (1291 aa)
ENSMLEP0000003173640S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (222 aa)
CRYBB3Uncharacterized protein; Belongs to the beta/gamma-crystallin family. (113 aa)
RPS640S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (218 aa)
PRKAR2BProtein kinase cAMP-dependent type II regulatory subunit beta. (378 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
PHKG2Phosphorylase kinase catalytic subunit gamma 2; Belongs to the protein kinase superfamily. (410 aa)
RPS6KB2Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (487 aa)
IRS4Insulin receptor substrate 4. (1245 aa)
RHEBRas homolog, mTORC1 binding. (181 aa)
PPP1R3CProtein phosphatase 1 regulatory subunit 3C; Acts as a glycogen-targeting subunit for PP1 and regulates its activity. Activates glycogen synthase, reduces glycogen phosphorylase activity and limits glycogen breakdown. (317 aa)
CALM1Calmodulin 1; Belongs to the calmodulin family. (149 aa)
IRS1Insulin receptor substrate 1. (1242 aa)
PRKAR1BProtein kinase cAMP-dependent type I regulatory subunit beta. (381 aa)
PHKA2Phosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. (1235 aa)
SLC2A4Solute carrier family 2 member 4; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (509 aa)
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (668 aa)
CALML6Calmodulin like 6. (181 aa)
SH2B1SH2B adaptor protein 1. (666 aa)
G6PCGlucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (357 aa)
ENSMLEP00000040499Uncharacterized protein. (147 aa)
PPP1R3AProtein phosphatase 1 regulatory subunit 3A. (1120 aa)
PTPRFProtein tyrosine phosphatase receptor type F. (1913 aa)
PDPK13-phosphoinositide dependent protein kinase 1. (529 aa)
CALM3Calmodulin 3. (149 aa)
PRKAG1Protein kinase AMP-activated non-catalytic subunit gamma 1. (326 aa)
KIAA1671KIAA1671. (1758 aa)
PRKAB2Protein kinase AMP-activated non-catalytic subunit beta 2. (272 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
CBLBCbl proto-oncogene B. (982 aa)
PRKAA1Non-specific serine/threonine protein kinase. (559 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (745 aa)
PTPRDProtein tyrosine phosphatase receptor type D. (1912 aa)
RRADRRAD, Ras related glycolysis inhibitor and calcium channel regulator. (248 aa)
SHC1SHC adaptor protein 1. (584 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
PCK2Phosphoenolpyruvate carboxykinase 2, mitochondrial. (645 aa)
SHC2Uncharacterized protein. (483 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
ENSMLEP00000037200Uncharacterized protein. (71 aa)
RHOQRas homolog family member Q. (192 aa)
G6PC2Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (354 aa)
RHEBL1RHEB like 1. (183 aa)
MKNK1MAPK interacting serine/threonine kinase 1; Belongs to the protein kinase superfamily. (465 aa)
ENSMLEP00000038520Uncharacterized protein; Belongs to the calmodulin family. (91 aa)
PYGLAlpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (766 aa)
PCK1Phosphoenolpyruvate carboxykinase 1. (622 aa)
PDE3BPhosphodiesterase. (1113 aa)
SREBF2Sterol regulatory element binding transcription factor 2. (1138 aa)
HK1Hexokinase 1. (921 aa)
ENSMLEP00000012301Protein kinase domain-containing protein. (294 aa)
BMT2Base methyltransferase of 25S rRNA 2 homolog. (247 aa)
PPP1CBSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (322 aa)
FLOT2Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (502 aa)
GEMGTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (295 aa)
SHC4SHC adaptor protein 4. (630 aa)
FLOT1Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (427 aa)
MAP2K2Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (389 aa)
ENSMLEP00000015404Fork-head domain-containing protein. (531 aa)
HK3Hexokinase 3. (923 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
FBP1Fructose-bisphosphatase 1; Belongs to the FBPase class 1 family. (298 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
PPP1CASerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (355 aa)
ELK1ETS transcription factor ELK1. (428 aa)
PRKAG3Protein kinase AMP-activated non-catalytic subunit gamma 3. (489 aa)
ACACAAcetyl-CoA carboxylase alpha. (2383 aa)
ALKBH4AlkB homolog 4, lysine demethylase. (302 aa)
MAPK9Mitogen-activated protein kinase. (395 aa)
RPS6KB1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa)
FASNFatty acid synthase. (2510 aa)
PPP1R3DProtein phosphatase 1 regulatory subunit 3D. (246 aa)
ERASES cell expressed Ras. (233 aa)
SOCS2Suppressor of cytokine signaling 2. (198 aa)
MAPK10Mitogen-activated protein kinase. (477 aa)
GYS1Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan. (737 aa)
PTPN1Tyrosine-protein phosphatase non-receptor type. (435 aa)
REM1GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (298 aa)
PRKAB1Protein kinase AMP-activated non-catalytic subunit beta 1. (270 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa)
MYO9AMyosin IXA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2535 aa)
HKDC1Hexokinase domain containing 1. (917 aa)
EIF4EEukaryotic translation initiation factor 4E. (247 aa)
CRKCRK proto-oncogene, adaptor protein. (245 aa)
TBCATubulin-specific chaperone A; Belongs to the TBCA family. (131 aa)
ENSMLEP00000004236SRCR domain-containing protein; Belongs to the eukaryotic initiation factor 4E family. (184 aa)
CALML3Calmodulin like 3; Belongs to the calmodulin family. (149 aa)
ENSMLEP00000003823Uncharacterized protein. (201 aa)
LOC105540811Uncharacterized protein; Belongs to the calmodulin family. (128 aa)
PRKAA2Non-specific serine/threonine protein kinase. (542 aa)
BADBCL2 associated agonist of cell death. (167 aa)
HK2Hexokinase 2. (901 aa)
EXOC7Exocyst complex component 7; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. (690 aa)
ENSMLEP00000002280Biotin carboxylation domain-containing protein. (205 aa)
ENSMLEP00000002165Uncharacterized protein; Belongs to the calmodulin family. (95 aa)
INPPL1Inositol polyphosphate phosphatase like 1. (1235 aa)
ELK3ETS transcription factor ELK3. (407 aa)
PPP1R3BProtein phosphatase 1 regulatory subunit. (285 aa)
PIK3R2Uncharacterized protein. (587 aa)
INPP5AInositol polyphosphate-5-phosphatase A. (408 aa)
SHC3SHC adaptor protein 3. (444 aa)
PTPRSProtein tyrosine phosphatase receptor type S. (1704 aa)
EIF4EBP1Eukaryotic translation initiation factor 4E binding protein 1. (73 aa)
SOCS4Suppressor of cytokine signaling 4. (440 aa)
PRKAR1AUncharacterized protein. (381 aa)
CEP152Centrosomal protein 152. (1709 aa)
INSInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa)
ENSMLEP00000016272Uncharacterized protein. (374 aa)
SORBS2Sorbin and SH3 domain containing 2. (1200 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (596 aa)
FBP2Fructose-bisphosphatase 2; Belongs to the FBPase class 1 family. (339 aa)
INSRTyrosine-protein kinase receptor. (1301 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (706 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
PVALEFParvalbumin like EF-hand containing. (133 aa)
GYS2Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan. (703 aa)
PPP1R3FProtein phosphatase 1 regulatory subunit 3F. (453 aa)
PYGMAlpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (842 aa)
CALM2Calmodulin 2. (149 aa)
CRKLCRK like proto-oncogene, adaptor protein. (303 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
PPARGC1APPARG coactivator 1 alpha. (798 aa)
MKNK2MAPK interacting serine/threonine kinase 2; Belongs to the protein kinase superfamily. (383 aa)
MYO9BMyosin IXB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1906 aa)
SH2B2SH2B adaptor protein 2. (434 aa)
G6PC3Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (346 aa)
CALML4Calmodulin like 4. (193 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (352 aa)
TMEM145Transmembrane protein 145. (453 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (364 aa)
RAPGEF1Rap guanine nucleotide exchange factor 1. (1100 aa)
ENSMLEP0000002143040S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (210 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1299 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
SOS2SOS Ras/Rho guanine nucleotide exchange factor 2. (1317 aa)
PYGBAlpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (762 aa)
PKLRPyruvate kinase; Belongs to the pyruvate kinase family. (528 aa)
PHKA1Phosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. (1240 aa)
MAPK1Mitogen-activated protein kinase. (343 aa)
PHKBPhosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. Belongs to the phosphorylase b kinase regulatory chain family. (900 aa)
CBLCbl proto-oncogene. (881 aa)
CRYGNCrystallin gamma N; Belongs to the beta/gamma-crystallin family. (182 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (478 aa)
ENSMLEP00000024805Protein kinase domain-containing protein. (365 aa)
EIF4E2Eukaryotic translation initiation factor 4E family member 2; Belongs to the eukaryotic initiation factor 4E family. (249 aa)
ENSMLEP00000025175Phosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. Belongs to the phosphorylase b kinase regulatory chain family. (171 aa)
SORBS1Sorbin and SH3 domain containing 1. (1294 aa)
TSC1TSC complex subunit 1. (1162 aa)
ARAFA-Raf proto-oncogene, serine/threonine kinase. (604 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
EIF4E1BEukaryotic translation initiation factor 4E family member 1B; Belongs to the eukaryotic initiation factor 4E family. (246 aa)
LIPELipase E, hormone sensitive type. (1041 aa)
TRIP10Thyroid hormone receptor interactor 10. (589 aa)
PRKAG2Protein kinase AMP-activated non-catalytic subunit gamma 2. (506 aa)
PHKG1Phosphorylase kinase catalytic subunit gamma 1; Belongs to the protein kinase superfamily. (421 aa)
ENSMLEP00000027485PID domain-containing protein. (488 aa)
PPP1CCSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (355 aa)
AKT1Non-specific serine/threonine protein kinase. (432 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1073 aa)
SORBS3Sorbin and SH3 domain containing 3. (626 aa)
CSDE1Cold shock domain containing E1. (844 aa)
LOC10554920240S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (244 aa)
TSC2TSC complex subunit 2. (1807 aa)
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
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