(58 nodes) Regulation of lipolysis in adipocytes network (Mandrillus leucophaeus)

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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experimentally determined

Predicted Interactions

gene neighborhood

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textmining

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protein homology

Your Input:
	PLIN1	Perilipin; Belongs to the perilipin family. (431 aa)
	PIK3R2	Uncharacterized protein. (587 aa)
	ADCY4	Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
	ADRB2	Adrenoceptor beta 2. (415 aa)
	ADCY9	Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa)
	ADCY7	Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1082 aa)
	PRKG1	cGMP-dependent protein kinase. (686 aa)
	GNAS	GNAS complex locus. (998 aa)
	ADCY8	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1251 aa)
	PTGS1	Prostaglandin-endoperoxide synthase 1. (632 aa)
	GNAI2	G protein subunit alpha i2. (352 aa)
	AQP7	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (342 aa)
	ABHD5	Abhydrolase domain containing 5. (349 aa)
	SYCP1	Synaptonemal complex protein 1. (976 aa)
	NPY1R	Neuropeptide Y receptor Y1; Belongs to the G-protein coupled receptor 1 family. (383 aa)
	IRS4	Insulin receptor substrate 4. (1245 aa)
	ENSMLEP00000009558	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (279 aa)
	IRS1	Insulin receptor substrate 1. (1242 aa)
	FABP12	Fatty acid binding protein 12; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (140 aa)
	PRKG2	cGMP-dependent protein kinase. (762 aa)
	INS	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa)
	ADCY2	Adenylate cyclase 2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (901 aa)
	INSR	Tyrosine-protein kinase receptor. (1301 aa)
	PIK3CA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	NPY	Neuropeptide Y. (97 aa)
	NPPA	Natriuretic peptide A. (153 aa)
	PRKACA	Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (352 aa)
	CGA	Glycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. (150 aa)
	PMP2	Peripheral myelin protein 2; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (132 aa)
	PTGER3	Prostaglandin E receptor 3. (415 aa)
	AKT2	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
	ADCY1	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (338 aa)
	LOC105548340	Uncharacterized protein. (246 aa)
	PLAAT3	Phospholipase A and acyltransferase 3. (162 aa)
	ENSMLEP00000024790	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (294 aa)
	ADCY5	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1064 aa)
	PIK3CD	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
	GNAI3	G protein subunit alpha i3. (354 aa)
	LIPE	Lipase E, hormone sensitive type. (1041 aa)
	ADCY3	Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1146 aa)
	AKT1	Non-specific serine/threonine protein kinase. (432 aa)
	PIK3CB	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1073 aa)
	FABP9	Fatty acid binding protein 9; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (132 aa)
	MGLL	Monoglyceride lipase. (313 aa)
	PIK3R3	Phosphoinositide-3-kinase regulatory subunit 3. (461 aa)
	PRKACB	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
	TSHB	Thyroid stimulating hormone subunit beta. (138 aa)
	PIK3R1	Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
	GNAI1	G protein subunit alpha i1. (314 aa)
	NPR1	Guanylate cyclase. (900 aa)
	ADORA1	Adenosine receptor A1; Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (326 aa)
	PNPLA2	Patatin like phospholipase domain containing 2. (409 aa)
	AKT3	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
	ADCY6	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1168 aa)
	FABP4	Fatty acid binding protein 4; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (132 aa)
	PDE3B	Phosphodiesterase. (1113 aa)
	TSHR	Thyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (764 aa)
	PTGS2	Prostaglandin-endoperoxide synthase 2. (604 aa)

Your Current Organism:

Mandrillus leucophaeus

NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABHD5	LIPE	ENSMLEP00000007176	ENSMLEP00000026260	Abhydrolase domain containing 5.	Lipase E, hormone sensitive type.	0.505
ABHD5	MGLL	ENSMLEP00000007176	ENSMLEP00000029017	Abhydrolase domain containing 5.	Monoglyceride lipase.	0.479
ABHD5	PLIN1	ENSMLEP00000007176	ENSMLEP00000022502	Abhydrolase domain containing 5.	Perilipin; Belongs to the perilipin family.	0.880
ABHD5	PNPLA2	ENSMLEP00000007176	ENSMLEP00000036215	Abhydrolase domain containing 5.	Patatin like phospholipase domain containing 2.	0.960
ADCY1	ADCY2	ENSMLEP00000023897	ENSMLEP00000016572	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Adenylate cyclase 2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.409
ADCY1	ADCY7	ENSMLEP00000023897	ENSMLEP00000003573	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.427
ADCY1	ADCY8	ENSMLEP00000023897	ENSMLEP00000005323	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.569
ADCY1	ADCY9	ENSMLEP00000023897	ENSMLEP00000003506	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.584
ADCY1	AKT1	ENSMLEP00000023897	ENSMLEP00000027863	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Non-specific serine/threonine protein kinase.	0.586
ADCY1	AKT2	ENSMLEP00000023897	ENSMLEP00000021914	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.586
ADCY1	AKT3	ENSMLEP00000023897	ENSMLEP00000036989	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.586
ADCY1	GNAI1	ENSMLEP00000023897	ENSMLEP00000033846	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	G protein subunit alpha i1.	0.462
ADCY1	GNAI2	ENSMLEP00000023897	ENSMLEP00000005997	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	G protein subunit alpha i2.	0.620
ADCY1	GNAI3	ENSMLEP00000023897	ENSMLEP00000026254	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	G protein subunit alpha i3.	0.462
ADCY1	GNAS	ENSMLEP00000023897	ENSMLEP00000004090	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	GNAS complex locus.	0.746
ADCY1	LOC105548340	ENSMLEP00000023897	ENSMLEP00000024031	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Uncharacterized protein.	0.776
ADCY1	NPPA	ENSMLEP00000023897	ENSMLEP00000019977	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Natriuretic peptide A.	0.466
ADCY1	PDE3B	ENSMLEP00000023897	ENSMLEP00000039752	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Phosphodiesterase.	0.651
ADCY1	PRKACA	ENSMLEP00000023897	ENSMLEP00000020813	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily.	0.639
ADCY1	PRKACB	ENSMLEP00000023897	ENSMLEP00000032707	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily.	0.639