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KCNJ5 KCNJ5 GPER1 GPER1 AKT3 AKT3 KCNN1 KCNN1 HCN3 HCN3 PLCB3 PLCB3 GABBR2 GABBR2 KCNN2 KCNN2 GNA11 GNA11 KCNJ6 KCNJ6 KCNJ11 KCNJ11 PIK3R2 PIK3R2 CACNA1H CACNA1H ITPR2 ITPR2 ERAS ERAS KISS1 KISS1 PLCB1 PLCB1 KRAS KRAS PLCB4 PLCB4 GNAQ GNAQ ITPR1 ITPR1 SPP1 SPP1 RAF1 RAF1 TRPC5 TRPC5 TRPC4 TRPC4 ARRB2 ARRB2 GNRH2 GNRH2 MAP2K2 MAP2K2 KCNJ9 KCNJ9 PIK3CA PIK3CA KCNN4 KCNN4 CACNA1D CACNA1D MAP2K1 MAP2K1 PRKCA PRKCA CGA CGA MAPK3 MAPK3 HCN1 HCN1 CACNA1F CACNA1F AKT2 AKT2 CACNA1G CACNA1G ITPR3 ITPR3 GABBR1 GABBR1 PLCB2 PLCB2 MAPK1 MAPK1 ESR2 ESR2 PRKCB PRKCB PRKCG PRKCG ENSMLEP00000024805 ENSMLEP00000024805 KCNJ3 KCNJ3 ARR3 ARR3 PIK3CD PIK3CD CACNA1C CACNA1C AKT1 AKT1 PIK3CB PIK3CB CACNA1I CACNA1I ARRB1 ARRB1 CSDE1 CSDE1 LHB LHB NRAS NRAS PIK3R3 PIK3R3 TRPC1 TRPC1 PIK3R1 PIK3R1 CACNA1S CACNA1S KCNN3 KCNN3 HRAS HRAS GNRH1 GNRH1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KCNJ5Potassium voltage-gated channel subfamily J member 5. (419 aa)
GPER1G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (400 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
KCNN1Potassium calcium-activated channel subfamily N member 1. (523 aa)
HCN3Hyperpolarization activated cyclic nucleotide gated potassium channel 3. (763 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1245 aa)
GABBR2Gamma-aminobutyric acid type B receptor subunit 2. (890 aa)
KCNN2Potassium calcium-activated channel subfamily N member 2. (540 aa)
GNA11G protein subunit alpha 11. (307 aa)
KCNJ6Potassium voltage-gated channel subfamily J member 6. (423 aa)
KCNJ11Potassium voltage-gated channel subfamily J member 11. (390 aa)
PIK3R2Uncharacterized protein. (587 aa)
CACNA1HCalcium voltage-gated channel subunit alpha1 H. (2170 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2663 aa)
ERASES cell expressed Ras. (233 aa)
KISS1KiSS-1 metastasis suppressor. (146 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1183 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1165 aa)
GNAQG protein subunit alpha q. (313 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2731 aa)
SPP1Secreted phosphoprotein 1. (314 aa)
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (668 aa)
TRPC5Transient receptor potential cation channel subfamily C member 5; Belongs to the transient receptor (TC 1.A.4) family. (974 aa)
TRPC4Transient receptor potential cation channel subfamily C member 4; Belongs to the transient receptor (TC 1.A.4) family. (982 aa)
ARRB2Arrestin beta 2. (478 aa)
GNRH2Gonadoliberin; Stimulates the secretion of gonadotropins. Belongs to the GnRH family. (121 aa)
MAP2K2Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (389 aa)
KCNJ9Potassium voltage-gated channel subfamily J member 9. (411 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
KCNN4Potassium calcium-activated channel subfamily N member 4. (375 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2181 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (614 aa)
CGAGlycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. (150 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (364 aa)
HCN1Hyperpolarization activated cyclic nucleotide gated potassium channel 1. (748 aa)
CACNA1FVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1960 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
CACNA1GVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2360 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2675 aa)
GABBR1Gamma-aminobutyric acid type B receptor subunit 1. (966 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1089 aa)
MAPK1Mitogen-activated protein kinase. (343 aa)
ESR2Estrogen receptor 2. (530 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (582 aa)
PRKCGProtein kinase C gamma; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (558 aa)
ENSMLEP00000024805Protein kinase domain-containing protein. (365 aa)
KCNJ3Potassium voltage-gated channel subfamily J member 3. (501 aa)
ARR3Arrestin 3. (389 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2169 aa)
AKT1Non-specific serine/threonine protein kinase. (432 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1073 aa)
CACNA1IVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2080 aa)
ARRB1Arrestin beta 1. (417 aa)
CSDE1Cold shock domain containing E1. (844 aa)
LHBCys_knot domain-containing protein. (141 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
PIK3R3Phosphoinositide-3-kinase regulatory subunit 3. (461 aa)
TRPC1Transient receptor potential cation channel subfamily C member 1; Belongs to the transient receptor (TC 1.A.4) family. (809 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1846 aa)
KCNN3Potassium calcium-activated channel subfamily N member 3. (748 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
GNRH1Gonadoliberin; Stimulates the secretion of gonadotropins. Belongs to the GnRH family. (92 aa)
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
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