STRINGSTRING
ENSMLEP00000002280 ENSMLEP00000002280 PPP1R3B PPP1R3B PIK3R2 PIK3R2 MLX MLX PTPRS PTPRS CREB3L1 CREB3L1 G6PC G6PC NR1H3 NR1H3 PCK1 PCK1 PYGL PYGL RPS6KA1 RPS6KA1 CREB3L2 CREB3L2 G6PC2 G6PC2 PTPA PTPA AKT3 AKT3 PCK2 PCK2 RELA RELA ENSMLEP00000035415 ENSMLEP00000035415 ENSMLEP00000035176 ENSMLEP00000035176 TNFRSF1A TNFRSF1A TRIB3 TRIB3 PRKAA1 PRKAA1 PRKCD PRKCD PIK3R1 PIK3R1 PRKAB2 PRKAB2 PPARGC1B PPARGC1B GFPT2 GFPT2 PRKAG1 PRKAG1 SLC27A3 SLC27A3 SREBF1 SREBF1 PIK3R3 PIK3R3 TBC1D4 TBC1D4 CREB5 CREB5 SLC27A6 SLC27A6 MLXIPL MLXIPL ENSMLEP00000028290 ENSMLEP00000028290 PIK3CB PIK3CB AKT1 AKT1 PPP1CC PPP1CC PRKAG2 PRKAG2 CPT1B CPT1B NFKBIA NFKBIA PIK3CD PIK3CD PTEN PTEN GSK3B GSK3B SLC2A2 SLC2A2 PRKCB PRKCB ENSMLEP00000023947 ENSMLEP00000023947 NFU1 NFU1 PYGB PYGB CPT1A CPT1A AKT2 AKT2 PPARA PPARA G6PC3 G6PC3 OGA OGA PPARGC1A PPARGC1A RPS6KA3 RPS6KA3 IL6 IL6 PIK3CA PIK3CA CREB1 CREB1 AGT AGT PYGM PYGM SLC27A4 SLC27A4 GYS2 GYS2 IKBKB IKBKB INSR INSR CRTC2 CRTC2 PRKCZ PRKCZ INS INS MAPK8 MAPK8 PRKCE PRKCE ENSMLEP00000015404 ENSMLEP00000015404 PRKCQ PRKCQ TNIK TNIK NOS3 NOS3 CREB3L4 CREB3L4 CD36 CD36 TPTE2 TPTE2 PPP1CB PPP1CB NFKB1 NFKB1 STAT3 STAT3 ENSMLEP00000012128 ENSMLEP00000012128 PDPK1 PDPK1 PTPRF PTPRF OGT OGT PPP1R3A PPP1R3A SLC27A1 SLC27A1 SLC2A4 SLC2A4 IRS1 IRS1 SLC27A5 SLC27A5 PPP1R3C PPP1R3C RPS6KB2 RPS6KB2 ENSMLEP00000008990 ENSMLEP00000008990 GFPT1 GFPT1 PPP1CA PPP1CA PRKAG3 PRKAG3 MAPK9 MAPK9 RPS6KB1 RPS6KB1 PPP1R3D PPP1R3D PTPN11 PTPN11 NR1H2 NR1H2 MAPK10 MAPK10 GYS1 GYS1 CREB3L3 CREB3L3 PTPN1 PTPN1 MLXIP MLXIP PRKAB1 PRKAB1 MTOR MTOR RPS6KA2 RPS6KA2 SLC2A1 SLC2A1 PRKAA2 PRKAA2 SLC27A2 SLC27A2 RPS6KA6 RPS6KA6 CREB3 CREB3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSMLEP00000002280Biotin carboxylation domain-containing protein. (205 aa)
PPP1R3BProtein phosphatase 1 regulatory subunit. (285 aa)
PIK3R2Uncharacterized protein. (587 aa)
MLXMAX dimerization protein MLX. (298 aa)
PTPRSProtein tyrosine phosphatase receptor type S. (1704 aa)
CREB3L1cAMP responsive element binding protein 3 like 1. (466 aa)
G6PCGlucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (357 aa)
NR1H3Nuclear receptor subfamily 1 group H member 3. (428 aa)
PCK1Phosphoenolpyruvate carboxykinase 1. (622 aa)
PYGLAlpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (766 aa)
RPS6KA1Ribosomal protein S6 kinase. (744 aa)
CREB3L2cAMP responsive element binding protein 3 like 2. (520 aa)
G6PC2Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (354 aa)
PTPASerine/threonine-protein phosphatase 2A activator; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. (358 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
PCK2Phosphoenolpyruvate carboxykinase 2, mitochondrial. (645 aa)
RELARELA proto-oncogene, NF-kB subunit. (550 aa)
ENSMLEP00000035415Uncharacterized protein. (519 aa)
ENSMLEP00000035176Uncharacterized protein. (77 aa)
TNFRSF1ATNF receptor superfamily member 1A. (455 aa)
TRIB3Tribbles pseudokinase 3. (385 aa)
PRKAA1Non-specific serine/threonine protein kinase. (559 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
PRKAB2Protein kinase AMP-activated non-catalytic subunit beta 2. (272 aa)
PPARGC1BPPARG coactivator 1 beta. (997 aa)
GFPT2Glutamine-fructose-6-phosphate transaminase 2. (637 aa)
PRKAG1Protein kinase AMP-activated non-catalytic subunit gamma 1. (326 aa)
SLC27A3Solute carrier family 27 member 3. (796 aa)
SREBF1Sterol regulatory element binding transcription factor 1. (1124 aa)
PIK3R3Phosphoinositide-3-kinase regulatory subunit 3. (461 aa)
TBC1D4TBC1 domain family member 4. (1132 aa)
CREB5Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription. (508 aa)
SLC27A6Solute carrier family 27 member 6. (619 aa)
MLXIPLMLX interacting protein like. (784 aa)
ENSMLEP00000028290Uncharacterized protein. (441 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1073 aa)
AKT1Non-specific serine/threonine protein kinase. (432 aa)
PPP1CCSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (355 aa)
PRKAG2Protein kinase AMP-activated non-catalytic subunit gamma 2. (506 aa)
CPT1BCarnitine palmitoyltransferase 1B; Belongs to the carnitine/choline acetyltransferase family. (642 aa)
NFKBIAANK_REP_REGION domain-containing protein. (305 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (478 aa)
SLC2A2Solute carrier family 2 member 2; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (525 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (582 aa)
ENSMLEP00000023947Nfu_N domain-containing protein. (232 aa)
NFU1NFU1 iron-sulfur cluster scaffold. (230 aa)
PYGBAlpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (762 aa)
CPT1ACarnitine palmitoyltransferase 1A; Belongs to the carnitine/choline acetyltransferase family. (753 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
PPARAPeroxisome proliferator activated receptor alpha. (365 aa)
G6PC3Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (346 aa)
OGAO-GlcNAcase. (926 aa)
PPARGC1APPARG coactivator 1 alpha. (798 aa)
RPS6KA3Ribosomal protein S6 kinase. (742 aa)
IL6Interleukin 6. (226 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
AGTAngiotensinogen; Belongs to the serpin family. (485 aa)
PYGMAlpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (842 aa)
SLC27A4Solute carrier family 27 member 4. (651 aa)
GYS2Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan. (703 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (706 aa)
INSRTyrosine-protein kinase receptor. (1301 aa)
CRTC2CREB regulated transcription coactivator 2. (694 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (596 aa)
INSInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
PRKCEProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (620 aa)
ENSMLEP00000015404Fork-head domain-containing protein. (531 aa)
PRKCQProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (706 aa)
TNIKTRAF2 and NCK interacting kinase. (1359 aa)
NOS3Nitric oxide synthase; Produces nitric oxide (NO). (1155 aa)
CREB3L4cAMP responsive element binding protein 3 like 4. (422 aa)
CD36CD36 molecule; Belongs to the CD36 family. (472 aa)
TPTE2Uncharacterized protein. (550 aa)
PPP1CBSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (322 aa)
NFKB1Nuclear factor kappa B subunit 1. (969 aa)
STAT3Signal transducer and activator of transcription. (693 aa)
ENSMLEP00000012128Uncharacterized protein. (234 aa)
PDPK13-phosphoinositide dependent protein kinase 1. (529 aa)
PTPRFProtein tyrosine phosphatase receptor type F. (1913 aa)
OGTO-linked N-acetylglucosamine (GlcNAc) transferase. (1046 aa)
PPP1R3AProtein phosphatase 1 regulatory subunit 3A. (1120 aa)
SLC27A1Solute carrier family 27 member 1. (626 aa)
SLC2A4Solute carrier family 2 member 4; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (509 aa)
IRS1Insulin receptor substrate 1. (1242 aa)
SLC27A5Solute carrier family 27 member 5. (690 aa)
PPP1R3CProtein phosphatase 1 regulatory subunit 3C; Acts as a glycogen-targeting subunit for PP1 and regulates its activity. Activates glycogen synthase, reduces glycogen phosphorylase activity and limits glycogen breakdown. (317 aa)
RPS6KB2Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (487 aa)
ENSMLEP00000008990Uncharacterized protein. (858 aa)
GFPT1Glutamine--fructose-6-phosphate transaminase 1. (699 aa)
PPP1CASerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (355 aa)
PRKAG3Protein kinase AMP-activated non-catalytic subunit gamma 3. (489 aa)
MAPK9Mitogen-activated protein kinase. (395 aa)
RPS6KB1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa)
PPP1R3DProtein phosphatase 1 regulatory subunit 3D. (246 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (656 aa)
NR1H2Nuclear receptor subfamily 1 group H member 2. (463 aa)
MAPK10Mitogen-activated protein kinase. (477 aa)
GYS1Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan. (737 aa)
CREB3L3cAMP responsive element binding protein 3 like 3. (321 aa)
PTPN1Tyrosine-protein phosphatase non-receptor type. (435 aa)
MLXIPMLX interacting protein. (856 aa)
PRKAB1Protein kinase AMP-activated non-catalytic subunit beta 1. (270 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa)
RPS6KA2Ribosomal protein S6 kinase. (728 aa)
SLC2A1Solute carrier family 2 member 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (506 aa)
PRKAA2Non-specific serine/threonine protein kinase. (542 aa)
SLC27A2Solute carrier family 27 member 2. (620 aa)
RPS6KA6Ribosomal protein S6 kinase. (744 aa)
CREB3cAMP responsive element binding protein 3. (372 aa)
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
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