STRINGSTRING
IL6 IL6 CALM1 CALM1 LOC105552669 LOC105552669 NFKB1 NFKB1 C4BPA C4BPA C3 C3 TLR4 TLR4 IRAK4 IRAK4 LOC105534152 LOC105534152 CASP3 CASP3 ENSMLEP00000008562 ENSMLEP00000008562 C1S C1S MAPK9 MAPK9 C1QB C1QB TMED7 TMED7 TICAM2 TICAM2 MAPK10 MAPK10 GNAI2 GNAI2 C1QC C1QC LOC105545893 LOC105545893 RHOC RHOC C1QA C1QA PYCARD PYCARD IL23A IL23A CALML3 CALML3 ENSMLEP00000003812 ENSMLEP00000003812 LOC105540811 LOC105540811 TRAF6 TRAF6 ENSMLEP00000002165 ENSMLEP00000002165 LY96 LY96 CFL2 CFL2 LOC105528457 LOC105528457 IL1A IL1A IL10 IL10 CXCL8 CXCL8 ITGAM ITGAM MYD88 MYD88 MAPK8 MAPK8 IL12A IL12A PVALEF PVALEF IL12B IL12B C5 C5 CALM2 CALM2 IRAK1 IRAK1 ENSMLEP00000019993 ENSMLEP00000019993 NLRP3 NLRP3 CALML4 CALML4 IRF1 IRF1 MAPK3 MAPK3 NOD1 NOD1 CASP1 CASP1 MAPK11 MAPK11 MAPK1 MAPK1 IL1B IL1B ITGA5 ITGA5 ITGB2 ITGB2 GNAI3 GNAI3 MAPK12 MAPK12 LOC105541822 LOC105541822 LOC105529698 LOC105529698 NOS2 NOS2 CCDC125 CCDC125 RHOA RHOA LOC105531511 LOC105531511 ITGB1 ITGB1 TICAM1 TICAM1 ENSMLEP00000029948 ENSMLEP00000029948 EFCAB13 EFCAB13 C4A C4A IRF3 IRF3 EFCAB3 EFCAB3 ENSMLEP00000031974 ENSMLEP00000031974 C1RL C1RL CD14 CD14 FOS FOS MAPK13 MAPK13 TMED3 TMED3 CALM3 CALM3 ENSMLEP00000033209 ENSMLEP00000033209 C4BPB C4BPB GNAI1 GNAI1 CXCL5 CXCL5 RELA RELA SERPING1 SERPING1 CASP7 CASP7 IRF8 IRF8 MAPK14 MAPK14 ENSMLEP00000038520 ENSMLEP00000038520 TIRAP TIRAP CXCL6 CXCL6 CALML6 CALML6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
IL6Interleukin 6. (226 aa)
CALM1Calmodulin 1; Belongs to the calmodulin family. (149 aa)
LOC105552669Uncharacterized protein; Belongs to the peptidase C14A family. (215 aa)
NFKB1Nuclear factor kappa B subunit 1. (969 aa)
C4BPAComplement component 4 binding protein alpha. (597 aa)
C3Complement C3. (1601 aa)
TLR4Toll like receptor 4; Belongs to the Toll-like receptor family. (843 aa)
IRAK4Interleukin 1 receptor associated kinase 4. (460 aa)
LOC105534152Uncharacterized protein; Belongs to the peptidase C14A family. (352 aa)
CASP3Uncharacterized protein; Belongs to the peptidase C14A family. (277 aa)
ENSMLEP00000008562Uncharacterized protein; Belongs to the peptidase S1 family. (734 aa)
C1SUncharacterized protein; Belongs to the peptidase S1 family. (688 aa)
MAPK9Mitogen-activated protein kinase. (395 aa)
C1QBComplement C1q B chain. (253 aa)
TMED7Transmembrane p24 trafficking protein 7. (224 aa)
TICAM2Toll like receptor adaptor molecule 2. (235 aa)
MAPK10Mitogen-activated protein kinase. (477 aa)
GNAI2G protein subunit alpha i2. (352 aa)
C1QCComplement C1q C chain. (245 aa)
LOC105545893ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (158 aa)
RHOCRas homolog family member C. (193 aa)
C1QAComplement C1q A chain. (245 aa)
PYCARDPYD and CARD domain containing. (195 aa)
IL23AInterleukin 23 subunit alpha. (189 aa)
CALML3Calmodulin like 3; Belongs to the calmodulin family. (149 aa)
ENSMLEP00000003812ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (158 aa)
LOC105540811Uncharacterized protein; Belongs to the calmodulin family. (128 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (522 aa)
ENSMLEP00000002165Uncharacterized protein; Belongs to the calmodulin family. (95 aa)
LY96Lymphocyte antigen 96. (160 aa)
CFL2Cofilin 2; Belongs to the actin-binding proteins ADF family. (166 aa)
LOC105528457ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (194 aa)
IL1AInterleukin-1; Belongs to the IL-1 family. (271 aa)
IL10Interleukin 10. (178 aa)
CXCL8Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (101 aa)
ITGAMIntegrin subunit alpha M; Belongs to the integrin alpha chain family. (1152 aa)
MYD88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (317 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
IL12AInterleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (253 aa)
PVALEFParvalbumin like EF-hand containing. (133 aa)
IL12BInterleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (328 aa)
C5Complement C5. (1676 aa)
CALM2Calmodulin 2. (149 aa)
IRAK1Interleukin 1 receptor associated kinase 1. (610 aa)
ENSMLEP00000019993ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (135 aa)
NLRP3NLR family pyrin domain containing 3. (1035 aa)
CALML4Calmodulin like 4. (193 aa)
IRF1Interferon regulatory factor. (325 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (364 aa)
NOD1Nucleotide binding oligomerization domain containing 1. (961 aa)
CASP1Caspase 1; Belongs to the peptidase C14A family. (404 aa)
MAPK11Mitogen-activated protein kinase. (224 aa)
MAPK1Mitogen-activated protein kinase. (343 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (268 aa)
ITGA5Integrin subunit alpha 5; Belongs to the integrin alpha chain family. (1053 aa)
ITGB2Integrin beta. (769 aa)
GNAI3G protein subunit alpha i3. (354 aa)
MAPK12Mitogen-activated protein kinase. (292 aa)
LOC105541822Complement C1r; Belongs to the peptidase S1 family. (719 aa)
LOC105529698Uncharacterized protein. (597 aa)
NOS2Nitric oxide synthase; Produces nitric oxide (NO). (1147 aa)
CCDC125Coiled-coil domain containing 125. (312 aa)
RHOARas homolog family member A. (193 aa)
LOC105531511NTR domain-containing protein. (131 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (748 aa)
TICAM1Toll like receptor adaptor molecule 1. (519 aa)
ENSMLEP00000029948EF-hand domain-containing protein; Belongs to the calmodulin family. (73 aa)
EFCAB13EF-hand calcium binding domain 13. (973 aa)
C4ANTR domain-containing protein. (131 aa)
IRF3Interferon regulatory factor 3. (422 aa)
EFCAB3EF-hand calcium binding domain 3. (488 aa)
ENSMLEP00000031974Uncharacterized protein; Belongs to the peptidase S1 family. (579 aa)
C1RLComplement C1r subcomponent like; Belongs to the peptidase S1 family. (487 aa)
CD14CD14 molecule. (383 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
MAPK13Mitogen-activated protein kinase. (397 aa)
TMED3Transmembrane p24 trafficking protein 3. (248 aa)
CALM3Calmodulin 3. (149 aa)
ENSMLEP00000033209ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (209 aa)
C4BPBComplement component 4 binding protein beta. (252 aa)
GNAI1G protein subunit alpha i1. (314 aa)
CXCL5C-X-C motif chemokine. (114 aa)
RELARELA proto-oncogene, NF-kB subunit. (550 aa)
SERPING1Serpin family G member 1; Belongs to the serpin family. (494 aa)
CASP7Caspase 7; Belongs to the peptidase C14A family. (336 aa)
IRF8Interferon regulatory factor 8. (434 aa)
MAPK14Mitogen-activated protein kinase. (350 aa)
ENSMLEP00000038520Uncharacterized protein; Belongs to the calmodulin family. (91 aa)
TIRAPTIR domain containing adaptor protein. (239 aa)
CXCL6C-X-C motif chemokine. (114 aa)
CALML6Calmodulin like 6. (181 aa)
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
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