STRINGSTRING
SPECC1 SPECC1 IL6 IL6 PIK3CA PIK3CA ARG2 ARG2 GNA15 GNA15 ENSMLEP00000019251 ENSMLEP00000019251 IL12B IL12B ENSMLEP00000018490 ENSMLEP00000018490 DCLK2 DCLK2 IL12A IL12A IL1R1 IL1R1 C8B C8B ACTN4 ACTN4 ITGAM ITGAM CXCL8 CXCL8 IL10 IL10 GNA14 GNA14 PTK2 PTK2 CD1E CD1E TLR4 TLR4 LOC105535159 LOC105535159 MFF MFF CD1A CD1A NFKB1 NFKB1 LOC105552669 LOC105552669 ENSMLEP00000011508 ENSMLEP00000011508 CD1B CD1B VCL VCL GNAQ GNAQ SERPINB9 SERPINB9 RAB5A RAB5A PLCB4 PLCB4 CD1C CD1C CASP3 CASP3 PLCB1 PLCB1 LAMA2 LAMA2 COL4A3 COL4A3 CXCL2 CXCL2 GNAS GNAS SERPINB6 SERPINB6 SERPINB8 SERPINB8 C9 C9 TGFB1 TGFB1 LOC105531130 LOC105531130 PRDX2 PRDX2 PIK3R2 PIK3R2 RAB7B RAB7B LOC105536632 LOC105536632 GNA11 GNA11 TLR2 TLR2 COL3A1 COL3A1 ENSMLEP00000040171 ENSMLEP00000040171 LOC105531126 LOC105531126 LAMB4 LAMB4 PLCB3 PLCB3 LAMB1 LAMB1 GNAL GNAL COL4A2 COL4A2 PRDX1 PRDX1 CD1D CD1D TGFB2 TGFB2 SMTN SMTN RELA RELA C8G C8G IL1R2 IL1R2 PIK3R1 PIK3R1 HMSD HMSD RAB17 RAB17 LOC105535158 LOC105535158 COL4A5 COL4A5 SMTNL2 SMTNL2 ACTN1 ACTN1 ENSMLEP00000033059 ENSMLEP00000033059 SERPINB10 SERPINB10 RAB7A RAB7A PRKACB PRKACB CD14 CD14 LAMC1 LAMC1 TGFB3 TGFB3 LAMA4 LAMA4 ENSMLEP00000031588 ENSMLEP00000031588 COL4A1 COL4A1 PIK3R3 PIK3R3 SMTNL1 SMTNL1 SPECC1L SPECC1L LAMC2 LAMC2 COL4A6 COL4A6 LAMA3 LAMA3 SERPINB13 SERPINB13 COL1A2 COL1A2 TRANK1 TRANK1 PIK3CB PIK3CB NOS2 NOS2 FN1 FN1 CTSG CTSG CSF2 CSF2 PIK3CD PIK3CD ITGB2 ITGB2 CXCL1 CXCL1 MUC2 MUC2 ENSMLEP00000024790 ENSMLEP00000024790 IL1B IL1B PRKCG PRKCG ARG1 ARG1 LAMA1 LAMA1 LAMA5 LAMA5 PRKCB PRKCB COL4A4 COL4A4 RAB5C RAB5C LOC105548340 LOC105548340 ADCY1 ADCY1 ENSMLEP00000023777 ENSMLEP00000023777 PLCB2 PLCB2 LAMB3 LAMB3 IFNG IFNG LAMC3 LAMC3 PRKCA PRKCA PRKACA PRKACA RAB5B RAB5B COL1A1 COL1A1 C8A C8A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SPECC1Sperm antigen with calponin homology and coiled-coil domains 1. (1068 aa)
IL6Interleukin 6. (226 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
ARG2Arginase. (354 aa)
GNA15G protein subunit alpha 15. (374 aa)
ENSMLEP00000019251Thioredoxin domain-containing protein. (192 aa)
IL12BInterleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (328 aa)
ENSMLEP00000018490Uncharacterized protein. (145 aa)
DCLK2Doublecortin like kinase 2. (755 aa)
IL12AInterleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (253 aa)
IL1R1Interleukin 1 receptor type 1. (569 aa)
C8BComplement C8 beta chain. (542 aa)
ACTN4Actinin alpha 4. (892 aa)
ITGAMIntegrin subunit alpha M; Belongs to the integrin alpha chain family. (1152 aa)
CXCL8Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (101 aa)
IL10Interleukin 10. (178 aa)
GNA14G protein subunit alpha 14. (355 aa)
PTK2Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1096 aa)
CD1ECD1e molecule. (387 aa)
TLR4Toll like receptor 4; Belongs to the Toll-like receptor family. (843 aa)
LOC105535159SERPIN domain-containing protein; Belongs to the serpin family. (379 aa)
MFFMitochondrial fission factor. (342 aa)
CD1ACD1a molecule. (292 aa)
NFKB1Nuclear factor kappa B subunit 1. (969 aa)
LOC105552669Uncharacterized protein; Belongs to the peptidase C14A family. (215 aa)
ENSMLEP00000011508C-X-C motif chemokine. (86 aa)
CD1BCD1b molecule. (333 aa)
VCLVinculin. (1134 aa)
GNAQG protein subunit alpha q. (313 aa)
SERPINB9Serpin family B member 9; Belongs to the serpin family. (376 aa)
RAB5ARAB5A, member RAS oncogene family. (215 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1165 aa)
CD1CCD1c molecule. (332 aa)
CASP3Uncharacterized protein; Belongs to the peptidase C14A family. (277 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1183 aa)
LAMA2Laminin subunit alpha 2. (2528 aa)
COL4A3Collagen type IV alpha 3 chain. (1635 aa)
CXCL2C-X-C motif chemokine. (107 aa)
GNASGNAS complex locus. (998 aa)
SERPINB6Serpin family B member 6; Belongs to the serpin family. (395 aa)
SERPINB8Serpin family B member 8; Belongs to the serpin family. (374 aa)
C9Complement C9. (561 aa)
TGFB1Transforming growth factor beta 1. (226 aa)
LOC105531130C-X-C motif chemokine. (154 aa)
PRDX2Peroxiredoxin 2. (198 aa)
PIK3R2Uncharacterized protein. (587 aa)
RAB7BRAB7B, member RAS oncogene family. (199 aa)
LOC105536632Uncharacterized protein. (598 aa)
GNA11G protein subunit alpha 11. (307 aa)
TLR2Toll-like receptor. (784 aa)
COL3A1Collagen type III alpha 1 chain. (1466 aa)
ENSMLEP00000040171Ig-like domain-containing protein. (156 aa)
LOC105531126C-X-C motif chemokine. (107 aa)
LAMB4Laminin subunit beta 4. (1729 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1245 aa)
LAMB1Laminin subunit beta 1. (1786 aa)
GNALG protein subunit alpha L. (309 aa)
COL4A2Collagen type IV alpha 2 chain. (1673 aa)
PRDX1Peroxiredoxin 1. (199 aa)
CD1DCD1d molecule. (331 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
SMTNSmoothelin. (1002 aa)
RELARELA proto-oncogene, NF-kB subunit. (550 aa)
C8GComplement C8 gamma chain. (201 aa)
IL1R2Interleukin 1 receptor type 2. (398 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
HMSDHistocompatibility minor serpin domain containing; Belongs to the serpin family. (147 aa)
RAB17RAB17, member RAS oncogene family. (212 aa)
LOC105535158SERPIN domain-containing protein; Belongs to the serpin family. (379 aa)
COL4A5Collagen type IV alpha 5 chain. (1661 aa)
SMTNL2Smoothelin like 2. (317 aa)
ACTN1Actinin alpha 1. (914 aa)
ENSMLEP00000033059Ig-like domain-containing protein. (153 aa)
SERPINB10Serpin family B member 10; Belongs to the serpin family. (397 aa)
RAB7ARAB7A, member RAS oncogene family. (207 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
CD14CD14 molecule. (383 aa)
LAMC1Laminin subunit gamma 1. (1575 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
LAMA4Laminin subunit alpha 4. (1823 aa)
ENSMLEP00000031588Ig-like domain-containing protein. (117 aa)
COL4A1Collagen type IV alpha 1 chain. (1641 aa)
PIK3R3Phosphoinositide-3-kinase regulatory subunit 3. (461 aa)
SMTNL1Smoothelin like 1. (496 aa)
SPECC1LSperm antigen with calponin homology and coiled-coil domains 1 like. (1117 aa)
LAMC2Laminin subunit gamma 2. (1193 aa)
COL4A6Collagen type IV alpha 6 chain. (1705 aa)
LAMA3Laminin subunit alpha 3. (3333 aa)
SERPINB13Serpin family B member 13; Belongs to the serpin family. (352 aa)
COL1A2Collagen type I alpha 2 chain. (1366 aa)
TRANK1Tetratricopeptide repeat and ankyrin repeat containing 1. (2925 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1073 aa)
NOS2Nitric oxide synthase; Produces nitric oxide (NO). (1147 aa)
FN1Fibronectin 1. (2384 aa)
CTSGCathepsin G; Belongs to the peptidase S1 family. (255 aa)
CSF2Colony stimulating factor 2. (144 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
ITGB2Integrin beta. (769 aa)
CXCL1C-X-C motif chemokine. (107 aa)
MUC2Uncharacterized protein. (2754 aa)
ENSMLEP00000024790Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (294 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (268 aa)
PRKCGProtein kinase C gamma; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (558 aa)
ARG1Arginase. (322 aa)
LAMA1Laminin subunit alpha 1. (3008 aa)
LAMA5Laminin subunit alpha 5. (3494 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (582 aa)
COL4A4Collagen type IV alpha 4 chain. (1692 aa)
RAB5CRAB5C, member RAS oncogene family. (249 aa)
LOC105548340Uncharacterized protein. (246 aa)
ADCY1Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (338 aa)
ENSMLEP00000023777Uncharacterized protein. (177 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1089 aa)
LAMB3Laminin subunit beta 3. (1172 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (165 aa)
LAMC3Laminin subunit gamma 3. (1423 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (614 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (352 aa)
RAB5BRAB5B, member RAS oncogene family. (221 aa)
COL1A1Collagen type I alpha 1 chain. (1464 aa)
C8AComplement C8 alpha chain. (584 aa)
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
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