STRINGSTRING
CX3CL1 CX3CL1 CALML6 CALML6 CREB3L1 CREB3L1 RAC3 RAC3 PTGS2 PTGS2 CCL3 CCL3 IL6R IL6R PLCB3 PLCB3 ENSMLEP00000038520 ENSMLEP00000038520 MAPK14 MAPK14 PTGER1 PTGER1 RHEBL1 RHEBL1 CREB3L2 CREB3L2 ADCY6 ADCY6 CALR CALR GNG13 GNG13 TRAF2 TRAF2 ROCK1 ROCK1 SP1 SP1 TP53 TP53 AKT3 AKT3 MDM2 MDM2 HRAS HRAS CASP9 CASP9 TAP1 TAP1 GNG8 GNG8 ENSMLEP00000035626 ENSMLEP00000035626 RELA RELA SRC SRC TNFRSF1A TNFRSF1A GNAI1 GNAI1 PIK3R1 PIK3R1 GNGT1 GNGT1 TRAF5 TRAF5 BCAR1 BCAR1 CALM3 CALM3 ENSMLEP00000033047 ENSMLEP00000033047 CGAS CGAS PRKACB PRKACB MAPK13 MAPK13 IL10RB IL10RB GNA13 GNA13 TAP2 TAP2 LOC105548563 LOC105548563 GNG4 GNG4 FAS FAS ENSMLEP00000031001 ENSMLEP00000031001 PIK3R3 PIK3R3 IRF3 IRF3 NRAS NRAS TSC2 TSC2 GNG3 GNG3 CREB5 CREB5 GNG5 GNG5 CSDE1 CSDE1 GNG12 GNG12 VEGFA VEGFA GNAO1 GNAO1 ENSMLEP00000028401 ENSMLEP00000028401 ENSMLEP00000028396 ENSMLEP00000028396 GNA12 GNA12 JAK1 JAK1 RHOA RHOA PIK3CB PIK3CB PPP3R1 PPP3R1 AKT1 AKT1 FADD FADD MAPK12 MAPK12 ADCY3 ADCY3 FASLG FASLG ENSMLEP00000026510 ENSMLEP00000026510 GNAI3 GNAI3 LOC105537894 LOC105537894 CDK4 CDK4 NFKBIA NFKBIA PIK3CD PIK3CD NFATC1 NFATC1 CDK6 CDK6 TSC1 TSC1 GNGT2 GNGT2 ADCY5 ADCY5 ENSMLEP00000024805 ENSMLEP00000024805 C7orf31 C7orf31 ENSMLEP00000024790 ENSMLEP00000024790 IL1B IL1B PRKCG PRKCG GSK3B GSK3B PRKCB PRKCB PPP3CB PPP3CB EGFR EGFR LOC105548340 LOC105548340 E2F3 E2F3 ADCY1 ADCY1 GNB2 GNB2 MAPK1 MAPK1 CHUK CHUK MAPK11 MAPK11 PLCB2 PLCB2 TBK1 TBK1 GNB5 GNB5 ATF2 ATF2 ITPR3 ITPR3 SOS2 SOS2 AKT2 AKT2 PTGER3 PTGER3 RB1 RB1 SOS1 SOS1 MAPK3 MAPK3 TRADD TRADD PRKCA PRKCA PRKACA PRKACA NFATC2 NFATC2 CALML4 CALML4 GNB1 GNB1 MAP2K1 MAP2K1 ENSMLEP00000019778 ENSMLEP00000019778 IL6 IL6 PIK3CA PIK3CA CRKL CRKL CREB1 CREB1 CALM2 CALM2 CCL2 CCL2 ATF6B ATF6B BID BID BAK1 BAK1 RAC2 RAC2 CCL4L2 CCL4L2 STING1 STING1 PVALEF PVALEF CCL5 CCL5 CDKN2A CDKN2A IL10RA IL10RA GRB2 GRB2 MYC MYC IKBKB IKBKB PTGER2 PTGER2 ENSMLEP00000017019 ENSMLEP00000017019 ADCY2 ADCY2 IL1R1 IL1R1 IKBKG IKBKG ENSMLEP00000016260 ENSMLEP00000016260 CASP8 CASP8 AKAP13 AKAP13 ENSMLEP00000015528 ENSMLEP00000015528 CXCL8 CXCL8 MAP2K2 MAP2K2 ITGB3 ITGB3 PTK2 PTK2 ENSMLEP00000014987 ENSMLEP00000014987 LOC105549769 LOC105549769 E2F2 E2F2 MAP2K6 MAP2K6 CCR3 CCR3 PTK2B PTK2B CREB3L4 CREB3L4 PTGER4 PTGER4 NFKB1 NFKB1 LOC105552669 LOC105552669 STAT3 STAT3 ENSMLEP00000012226 ENSMLEP00000012226 CXCL12 CXCL12 CDKN1A CDKN1A RAF1 RAF1 PDGFRA PDGFRA NFATC4 NFATC4 CALM1 CALM1 NFATC3 NFATC3 B2M B2M PDIA3 PDIA3 PPP3CA PPP3CA LPXN LPXN ROCK2 ROCK2 ITPR1 ITPR1 LOC105533269 LOC105533269 RHEB RHEB GNAQ GNAQ PLCB4 PLCB4 LOC105550079 LOC105550079 CTNNB1 CTNNB1 CASP3 CASP3 GNG2 GNG2 RPS6KB2 RPS6KB2 ARHGEF1 ARHGEF1 LOC105535298 LOC105535298 LOC105548879 LOC105548879 KRAS KRAS ELK1 ELK1 ENSMLEP00000007765 ENSMLEP00000007765 LOC105533615 LOC105533615 PLCB1 PLCB1 ENSMLEP00000007417 ENSMLEP00000007417 RPS6KB1 RPS6KB1 RUFY4 RUFY4 ERAS ERAS ENSMLEP00000006706 ENSMLEP00000006706 CCR5 CCR5 LOC105533249 LOC105533249 ARHGEF12 ARHGEF12 CREB3L3 CREB3L3 TAPBP TAPBP GNB3 GNB3 ITPR2 ITPR2 RIPK1 RIPK1 GNAI2 GNAI2 ENSMLEP00000005644 ENSMLEP00000005644 ATF4 ATF4 MTOR MTOR ADCY8 ADCY8 RHOC RHOC CRK CRK ARHGEF11 ARHGEF11 ITGAV ITGAV GNAS GNAS CALML3 CALML3 BAX BAX LOC105540811 LOC105540811 ADCY7 ADCY7 PPP3CC PPP3CC CXCR4 CXCR4 ADCY9 ADCY9 GNB4 GNB4 ADCY4 ADCY4 CREB3 CREB3 ENSMLEP00000002165 ENSMLEP00000002165 ENSMLEP00000001951 ENSMLEP00000001951 PXN PXN PIK3R2 PIK3R2 LOC105553485 LOC105553485 HLA-E HLA-E LOC105533617 LOC105533617 GNA11 GNA11 E2F1 E2F1 LOC105553918 LOC105553918 ENSMLEP00000001022 ENSMLEP00000001022 RAC1 RAC1 EIF4EBP1 EIF4EBP1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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CX3CL1C-X3-C motif chemokine ligand 1. (402 aa)
CALML6Calmodulin like 6. (181 aa)
CREB3L1cAMP responsive element binding protein 3 like 1. (466 aa)
RAC3Rac family small GTPase 3. (212 aa)
PTGS2Prostaglandin-endoperoxide synthase 2. (604 aa)
CCL3C-C motif chemokine. (92 aa)
IL6RInterleukin 6 receptor. (468 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1245 aa)
ENSMLEP00000038520Uncharacterized protein; Belongs to the calmodulin family. (91 aa)
MAPK14Mitogen-activated protein kinase. (350 aa)
PTGER1Prostaglandin E receptor 1. (402 aa)
RHEBL1RHEB like 1. (183 aa)
CREB3L2cAMP responsive element binding protein 3 like 2. (520 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1168 aa)
CALRCalreticulin. (417 aa)
GNG13Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (67 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1368 aa)
SP1Uncharacterized protein. (661 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (402 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
MDM2E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (497 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
CASP9Caspase 9; Belongs to the peptidase C14A family. (400 aa)
TAP1Transporter 1, ATP binding cassette subfamily B member. (738 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
ENSMLEP00000035626Ig-like domain-containing protein; Belongs to the MHC class I family. (313 aa)
RELARELA proto-oncogene, NF-kB subunit. (550 aa)
SRCTyrosine-protein kinase. (542 aa)
TNFRSF1ATNF receptor superfamily member 1A. (455 aa)
GNAI1G protein subunit alpha i1. (314 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
GNGT1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
TRAF5TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (557 aa)
BCAR1BCAR1 scaffold protein, Cas family member. (916 aa)
CALM3Calmodulin 3. (149 aa)
ENSMLEP00000033047Uncharacterized protein. (67 aa)
CGASCyclic GMP-AMP synthase. (447 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
MAPK13Mitogen-activated protein kinase. (397 aa)
IL10RBInterleukin 10 receptor subunit beta. (325 aa)
GNA13G protein subunit alpha 13. (282 aa)
TAP2Transporter 2, ATP binding cassette subfamily B member. (703 aa)
LOC105548563Uncharacterized protein. (245 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
FASFas cell surface death receptor. (331 aa)
ENSMLEP00000031001Ig-like domain-containing protein; Belongs to the MHC class I family. (333 aa)
PIK3R3Phosphoinositide-3-kinase regulatory subunit 3. (461 aa)
IRF3Interferon regulatory factor 3. (422 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
TSC2TSC complex subunit 2. (1807 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
CREB5Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription. (508 aa)
GNG5Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
CSDE1Cold shock domain containing E1. (844 aa)
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
VEGFAVascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (210 aa)
GNAO1G protein subunit alpha o1. (354 aa)
ENSMLEP00000028401Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (65 aa)
ENSMLEP00000028396IGc1 domain-containing protein. (205 aa)
GNA12G protein subunit alpha 12. (319 aa)
JAK1Tyrosine-protein kinase. (1154 aa)
RHOARas homolog family member A. (193 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1073 aa)
PPP3R1Uncharacterized protein. (189 aa)
AKT1Non-specific serine/threonine protein kinase. (432 aa)
FADDFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa)
MAPK12Mitogen-activated protein kinase. (292 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1146 aa)
FASLGFas ligand; Belongs to the tumor necrosis factor family. (280 aa)
ENSMLEP00000026510Ig-like domain-containing protein; Belongs to the MHC class I family. (301 aa)
GNAI3G protein subunit alpha i3. (354 aa)
LOC105537894Uncharacterized protein. (192 aa)
CDK4Cyclin dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa)
NFKBIAANK_REP_REGION domain-containing protein. (305 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
NFATC1Nuclear factor of activated T cells 1. (755 aa)
CDK6Cyclin dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa)
TSC1TSC complex subunit 1. (1162 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (88 aa)
ADCY5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1064 aa)
ENSMLEP00000024805Protein kinase domain-containing protein. (365 aa)
C7orf31Chromosome 7 open reading frame 31. (590 aa)
ENSMLEP00000024790Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (294 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (268 aa)
PRKCGProtein kinase C gamma; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (558 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (478 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (582 aa)
PPP3CBSerine/threonine-protein phosphatase. (524 aa)
EGFRReceptor protein-tyrosine kinase. (1188 aa)
LOC105548340Uncharacterized protein. (246 aa)
E2F3E2F transcription factor 3. (375 aa)
ADCY1Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (338 aa)
GNB2G protein subunit beta 2. (340 aa)
MAPK1Mitogen-activated protein kinase. (343 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (745 aa)
MAPK11Mitogen-activated protein kinase. (224 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1089 aa)
TBK1TANK binding kinase 1. (729 aa)
GNB5G protein subunit beta 5. (357 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2675 aa)
SOS2SOS Ras/Rho guanine nucleotide exchange factor 2. (1317 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
PTGER3Prostaglandin E receptor 3. (415 aa)
RB1RB transcriptional corepressor 1. (891 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1299 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (364 aa)
TRADDTNFRSF1A associated via death domain. (308 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (614 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (352 aa)
NFATC2Nuclear factor of activated T cells 2. (921 aa)
CALML4Calmodulin like 4. (193 aa)
GNB1G protein subunit beta 1. (340 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
ENSMLEP00000019778IGc1 domain-containing protein; Belongs to the MHC class I family. (327 aa)
IL6Interleukin 6. (226 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
CRKLCRK like proto-oncogene, adaptor protein. (303 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
CALM2Calmodulin 2. (149 aa)
CCL2C-C motif chemokine. (99 aa)
ATF6BActivating transcription factor 6 beta. (711 aa)
BIDBH3 interacting domain death agonist. (244 aa)
BAK1BCL2 antagonist/killer 1. (211 aa)
RAC2Rac family small GTPase 2. (192 aa)
CCL4L2SCY domain-containing protein. (75 aa)
STING1Transmembrane protein 173. (379 aa)
PVALEFParvalbumin like EF-hand containing. (133 aa)
CCL5C-C motif chemokine. (91 aa)
CDKN2ACyclin dependent kinase inhibitor 2A. (159 aa)
IL10RAInterleukin 10 receptor subunit alpha. (576 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (454 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (706 aa)
PTGER2Prostaglandin E receptor 2; Belongs to the G-protein coupled receptor 1 family. (358 aa)
ENSMLEP00000017019MHC_I-like_Ag-recog domain-containing protein. (157 aa)
ADCY2Adenylate cyclase 2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (901 aa)
IL1R1Interleukin 1 receptor type 1. (569 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (396 aa)
ENSMLEP00000016260MHC_I-like_Ag-recog domain-containing protein. (163 aa)
CASP8Caspase 8; Belongs to the peptidase C14A family. (479 aa)
AKAP13A-kinase anchoring protein 13. (2785 aa)
ENSMLEP00000015528Uncharacterized protein. (184 aa)
CXCL8Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (101 aa)
MAP2K2Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (389 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (788 aa)
PTK2Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1096 aa)
ENSMLEP00000014987IGc1 domain-containing protein; Belongs to the MHC class I family. (327 aa)
LOC105549769Uncharacterized protein. (182 aa)
E2F2E2F transcription factor 2. (437 aa)
MAP2K6Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (335 aa)
CCR3C-C motif chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (376 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
CREB3L4cAMP responsive element binding protein 3 like 4. (422 aa)
PTGER4Prostaglandin E receptor 4; Belongs to the G-protein coupled receptor 1 family. (470 aa)
NFKB1Nuclear factor kappa B subunit 1. (969 aa)
LOC105552669Uncharacterized protein; Belongs to the peptidase C14A family. (215 aa)
STAT3Signal transducer and activator of transcription. (693 aa)
ENSMLEP00000012226Uncharacterized protein. (198 aa)
CXCL12SCY domain-containing protein; Belongs to the intercrine alpha (chemokine CxC) family. (458 aa)
CDKN1ACyclin dependent kinase inhibitor 1A. (164 aa)
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (668 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa)
NFATC4Nuclear factor of activated T cells 4. (914 aa)
CALM1Calmodulin 1; Belongs to the calmodulin family. (149 aa)
NFATC3Nuclear factor of activated T cells 3. (1068 aa)
B2MBeta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. (119 aa)
PDIA3Protein disulfide-isomerase. (485 aa)
PPP3CASerine/threonine-protein phosphatase. (501 aa)
LPXNLeupaxin; Transcriptional coactivator for androgen receptor (AR) and serum response factor (SRF). Contributes to the regulation of cell adhesion, spreading and cell migration and acts as a negative regulator in integrin-mediated cell adhesion events. Suppresses the integrin- induced tyrosine phosphorylation of paxillin (PXN). (400 aa)
ROCK2Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1375 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2731 aa)
LOC105533269MHC_I_C domain-containing protein. (93 aa)
RHEBRas homolog, mTORC1 binding. (181 aa)
GNAQG protein subunit alpha q. (313 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1165 aa)
LOC105550079Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
CTNNB1Catenin beta 1. (781 aa)
CASP3Uncharacterized protein; Belongs to the peptidase C14A family. (277 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (110 aa)
RPS6KB2Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (487 aa)
ARHGEF1Rho guanine nucleotide exchange factor 1. (968 aa)
LOC105535298Ig-like domain-containing protein; Belongs to the MHC class I family. (345 aa)
LOC105548879C-C motif chemokine. (83 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
ELK1ETS transcription factor ELK1. (428 aa)
ENSMLEP00000007765Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
LOC105533615SCY domain-containing protein. (102 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1183 aa)
ENSMLEP00000007417Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
RPS6KB1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa)
RUFY4RUN and FYVE domain containing 4. (530 aa)
ERASES cell expressed Ras. (233 aa)
ENSMLEP00000006706Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (96 aa)
CCR5C-C chemokine receptor type 5; Receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation (By similarity). (352 aa)
LOC105533249Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (153 aa)
ARHGEF12Rho guanine nucleotide exchange factor 12. (1544 aa)
CREB3L3cAMP responsive element binding protein 3 like 3. (321 aa)
TAPBPTAP binding protein. (504 aa)
GNB3G protein subunit beta 3. (340 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2663 aa)
RIPK1Receptor interacting serine/threonine kinase 1. (620 aa)
GNAI2G protein subunit alpha i2. (352 aa)
ENSMLEP00000005644Ig-like domain-containing protein; Belongs to the MHC class I family. (216 aa)
ATF4Activating transcription factor 4. (351 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1251 aa)
RHOCRas homolog family member C. (193 aa)
CRKCRK proto-oncogene, adaptor protein. (245 aa)
ARHGEF11Rho guanine nucleotide exchange factor 11. (1562 aa)
ITGAVIntegrin subunit alpha V; Belongs to the integrin alpha chain family. (1048 aa)
GNASGNAS complex locus. (998 aa)
CALML3Calmodulin like 3; Belongs to the calmodulin family. (149 aa)
BAXBCL2 associated X, apoptosis regulator. (203 aa)
LOC105540811Uncharacterized protein; Belongs to the calmodulin family. (128 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1082 aa)
PPP3CCSerine/threonine-protein phosphatase. (438 aa)
CXCR4C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family. (408 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa)
GNB4G protein subunit beta 4. (340 aa)
ADCY4Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
CREB3cAMP responsive element binding protein 3. (372 aa)
ENSMLEP00000002165Uncharacterized protein; Belongs to the calmodulin family. (95 aa)
ENSMLEP00000001951Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (60 aa)
PXNPaxillin. (1079 aa)
PIK3R2Uncharacterized protein. (587 aa)
LOC105553485Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
HLA-EMajor histocompatibility complex, class I, E; Belongs to the MHC class I family. (364 aa)
LOC105533617C-C motif chemokine. (92 aa)
GNA11G protein subunit alpha 11. (307 aa)
E2F1E2F transcription factor 1. (381 aa)
LOC105553918Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
ENSMLEP00000001022Uncharacterized protein. (189 aa)
RAC1Uncharacterized protein. (280 aa)
EIF4EBP1Eukaryotic translation initiation factor 4E binding protein 1. (73 aa)
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
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