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| | MSH6 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1363 aa) |
| | MAP2K1 | Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | GADD45A | Growth arrest and DNA damage inducible alpha. (165 aa) |
| | BAK1 | BCL2 antagonist/killer 1. (211 aa) |
| | RAC2 | Rac family small GTPase 2. (192 aa) |
| | LOC105530438 | Ras-GEF domain-containing protein. (560 aa) |
| | GRB2 | Growth factor receptor bound protein 2. (217 aa) |
| | MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (454 aa) |
| | SMAD3 | Mothers against decapentaplegic homolog. (425 aa) |
| | DDB2 | Damage specific DNA binding protein 2. (427 aa) |
| | TGFA | Transforming growth factor alpha. (166 aa) |
| | AXIN1 | Axin 1. (859 aa) |
| | TCF7L2 | Transcription factor 7 like 2. (555 aa) |
| | MAPK8 | Mitogen-activated protein kinase. (427 aa) |
| | ENSMLEP00000015528 | Uncharacterized protein. (184 aa) |
| | MAP2K2 | Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (389 aa) |
| | GADD45G | Growth arrest and DNA damage inducible gamma. (159 aa) |
| | LOC105549769 | Uncharacterized protein. (182 aa) |
| | LOC105552366 | Ras-GEF domain-containing protein. (600 aa) |
| | EPGN | Epithelial mitogen. (154 aa) |
| | ENSMLEP00000014023 | Ras-GEF domain-containing protein. (387 aa) |
| | LOC105552669 | Uncharacterized protein; Belongs to the peptidase C14A family. (215 aa) |
| | ENSMLEP00000012301 | Protein kinase domain-containing protein. (294 aa) |
| | CDKN1A | Cyclin dependent kinase inhibitor 1A. (164 aa) |
| | RAF1 | Raf-1 proto-oncogene, serine/threonine kinase. (668 aa) |
| | RALA | RAS like proto-oncogene A. (206 aa) |
| | MLH1 | MutL homolog 1. (756 aa) |
| | AREG | Amphiregulin. (274 aa) |
| | AXIN2 | Axin 2. (843 aa) |
| | CTNNB1 | Catenin beta 1. (781 aa) |
| | CASP3 | Uncharacterized protein; Belongs to the peptidase C14A family. (277 aa) |
| | RPS6KB2 | Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (487 aa) |
| | KRAS | KRAS proto-oncogene, GTPase. (189 aa) |
| | ENSMLEP00000007765 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | SMAD4 | Mothers against decapentaplegic homolog. (552 aa) |
| | MAPK9 | Mitogen-activated protein kinase. (395 aa) |
| | RPS6KB1 | Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa) |
| | ERAS | ES cell expressed Ras. (233 aa) |
| | LEF1 | Lymphoid enhancer binding factor 1. (399 aa) |
| | ENSMLEP00000006706 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (96 aa) |
| | MSH2 | MutS homolog 2; Component of the post-replicative DNA mismatch repair system (MMR). (845 aa) |
| | LOC105533249 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (153 aa) |
| | MAPK10 | Mitogen-activated protein kinase. (477 aa) |
| | EGF | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1152 aa) |
| | BCL2 | BCL2 apoptosis regulator. (239 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa) |
| | RHOC | Ras homolog family member C. (193 aa) |
| | APPL1 | Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1. (694 aa) |
| | BAX | BCL2 associated X, apoptosis regulator. (203 aa) |
| | BAD | BCL2 associated agonist of cell death. (167 aa) |
| | ENSMLEP00000003362 | Uncharacterized protein. (185 aa) |
| | TGFB1 | Transforming growth factor beta 1. (226 aa) |
| | DCC | DCC netrin 1 receptor. (976 aa) |
| | RALB | RAS like proto-oncogene B. (212 aa) |
| | RALGDS | Uncharacterized protein. (911 aa) |
| | PIK3R2 | Uncharacterized protein. (587 aa) |
| | LOC105553485 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | LOC105553918 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | ENSMLEP00000001022 | Uncharacterized protein. (189 aa) |
| | RAC1 | Uncharacterized protein. (280 aa) |
| | ENSMLEP00000040499 | Uncharacterized protein. (147 aa) |
| | RAC3 | Rac family small GTPase 3. (212 aa) |
| | LOC105537660 | Uncharacterized protein. (140 aa) |
| | RGL4 | Ras-GEF domain-containing protein. (591 aa) |
| | POLK | DNA polymerase kappa. (870 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (402 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | TGFBR2 | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (560 aa) |
| | TGFB2 | Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa) |
| | HRAS | HRas proto-oncogene, GTPase. (189 aa) |
| | CASP9 | Caspase 9; Belongs to the peptidase C14A family. (400 aa) |
| | MSH3 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1125 aa) |
| | BRAF | B-Raf proto-oncogene, serine/threonine kinase. (745 aa) |
| | PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (724 aa) |
| | APC | APC regulator of WNT signaling pathway. (2806 aa) |
| | ENSMLEP00000033047 | Uncharacterized protein. (67 aa) |
| | FOS | Fos proto-oncogene, AP-1 transcription factor subunit. (380 aa) |
| | PMAIP1 | Uncharacterized protein. (133 aa) |
| | EREG | Epiregulin. (169 aa) |
| | TGFB3 | Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa) |
| | PIK3R3 | Phosphoinositide-3-kinase regulatory subunit 3. (461 aa) |
| | PPP1R14B | Uncharacterized protein. (127 aa) |
| | NRAS | NRAS proto-oncogene, GTPase. (189 aa) |
| | CSDE1 | Cold shock domain containing E1. (844 aa) |
| | ENSMLEP00000029067 | Uncharacterized protein. (101 aa) |
| | RHOA | Ras homolog family member A. (193 aa) |
| | LOC105540582 | Ras-GEF domain-containing protein. (407 aa) |
| | PIK3CB | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1073 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase. (432 aa) |
| | SMAD2 | Mothers against decapentaplegic homolog. (457 aa) |
| | TCF7 | Transcription factor 7. (269 aa) |
| | ENSMLEP00000026117 | annotation not available (172 aa) |
| | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa) |
| | ARAF | A-Raf proto-oncogene, serine/threonine kinase. (604 aa) |
| | LOC105533469 | Ras-GEF domain-containing protein. (540 aa) |
| | ENSMLEP00000024805 | Protein kinase domain-containing protein. (365 aa) |
| | C7orf31 | Chromosome 7 open reading frame 31. (590 aa) |
| | GSK3B | Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (478 aa) |
| | APC2 | APC regulator of WNT signaling pathway 2. (1668 aa) |
| | EGFR | Receptor protein-tyrosine kinase. (1188 aa) |
| | BCL2L11 | Bcl-2-like protein 11; Induces apoptosis and anoikis. Belongs to the Bcl-2 family. (198 aa) |
| | GADD45B | Growth arrest and DNA damage inducible beta. (176 aa) |
| | MAPK1 | Mitogen-activated protein kinase. (343 aa) |
| | SOS2 | SOS Ras/Rho guanine nucleotide exchange factor 2. (1317 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) |
| | SOS1 | SOS Ras/Rac guanine nucleotide exchange factor 1. (1299 aa) |
| | TGFBR1 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (502 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (364 aa) |
| | TCF7L1 | Transcription factor 7 like 1. (432 aa) |
