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| | BRAF | B-Raf proto-oncogene, serine/threonine kinase. (745 aa) |
| | CREB3L1 | cAMP responsive element binding protein 3 like 1. (466 aa) |
| | ENSMLEP00000040499 | Uncharacterized protein. (147 aa) |
| | CREB3L2 | cAMP responsive element binding protein 3 like 2. (520 aa) |
| | MMP3 | Matrix metallopeptidase 3. (477 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (402 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | MDM2 | E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (497 aa) |
| | HRAS | HRas proto-oncogene, GTPase. (189 aa) |
| | CASP9 | Caspase 9; Belongs to the peptidase C14A family. (400 aa) |
| | RELA | RELA proto-oncogene, NF-kB subunit. (550 aa) |
| | MMP9 | Matrix metallopeptidase 9. (707 aa) |
| | ENSMLEP00000035176 | Uncharacterized protein. (77 aa) |
| | IL1R2 | Interleukin 1 receptor type 2. (398 aa) |
| | ZEB1 | Zinc finger E-box binding homeobox 1. (1127 aa) |
| | PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (724 aa) |
| | ENSMLEP00000033047 | Uncharacterized protein. (67 aa) |
| | HSP90AA1 | Heat shock protein 90 alpha family class A member 1. (823 aa) |
| | EP300 | E1A binding protein p300. (2411 aa) |
| | PIK3R3 | Phosphoinositide-3-kinase regulatory subunit 3. (461 aa) |
| | PDGFB | Platelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (241 aa) |
| | CCNE1 | Cyclin E1; Belongs to the cyclin family. (407 aa) |
| | PLAU | Plasminogen activator, urokinase. (428 aa) |
| | PPP1R14B | Uncharacterized protein. (127 aa) |
| | ETV5 | ETS variant 5. (510 aa) |
| | NRAS | NRAS proto-oncogene, GTPase. (189 aa) |
| | PDGFA | PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (287 aa) |
| | CREB5 | Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription. (508 aa) |
| | AR | Androgen receptor. (894 aa) |
| | CSDE1 | Cold shock domain containing E1. (844 aa) |
| | PIK3CB | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1073 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase. (432 aa) |
| | PDGFC | Platelet derived growth factor C; Belongs to the PDGF/VEGF growth factor family. (345 aa) |
| | LOC105542545 | HATPase_c domain-containing protein. (626 aa) |
| | TCF7 | Transcription factor 7. (269 aa) |
| | NFKBIA | ANK_REP_REGION domain-containing protein. (305 aa) |
| | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa) |
| | ARAF | A-Raf proto-oncogene, serine/threonine kinase. (604 aa) |
| | PTEN | Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa) |
| | ENSMLEP00000024805 | Protein kinase domain-containing protein. (365 aa) |
| | LOC105538379 | HATPase_c domain-containing protein. (673 aa) |
| | GSK3B | Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (478 aa) |
| | IGF1R | Tyrosine-protein kinase receptor. (1281 aa) |
| | EGFR | Receptor protein-tyrosine kinase. (1188 aa) |
| | E2F3 | E2F transcription factor 3. (375 aa) |
| | MAPK1 | Mitogen-activated protein kinase. (343 aa) |
| | CHUK | Component of inhibitor of nuclear factor kappa B kinase complex. (745 aa) |
| | SOS2 | SOS Ras/Rho guanine nucleotide exchange factor 2. (1317 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) |
| | RB1 | RB transcriptional corepressor 1. (891 aa) |
| | SOS1 | SOS Ras/Rac guanine nucleotide exchange factor 1. (1299 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (364 aa) |
| | TCF7L1 | Transcription factor 7 like 1. (432 aa) |
| | MAP2K1 | Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | ERG | ETS transcription factor ERG. (486 aa) |
| | CREB1 | cAMP responsive element binding protein 1. (341 aa) |
| | GRB2 | Growth factor receptor bound protein 2. (217 aa) |
| | IKBKB | Inhibitor of nuclear factor kappa B kinase subunit beta. (706 aa) |
| | ERBB2 | Receptor protein-tyrosine kinase. (1260 aa) |
| | LOC105534642 | Uncharacterized protein. (401 aa) |
| | IKBKG | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (396 aa) |
| | TGFA | Transforming growth factor alpha. (166 aa) |
| | INS | Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa) |
| | TCF7L2 | Transcription factor 7 like 2. (555 aa) |
| | ENSMLEP00000015404 | Fork-head domain-containing protein. (531 aa) |
| | MAP2K2 | Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (389 aa) |
| | E2F2 | E2F transcription factor 2. (437 aa) |
| | MMP10 | Matrix metallopeptidase 10. (476 aa) |
| | CCNE2 | Cyclin E2; Belongs to the cyclin family. (404 aa) |
| | CREB3L4 | cAMP responsive element binding protein 3 like 4. (422 aa) |
| | TPTE2 | Uncharacterized protein. (550 aa) |
| | ENSMLEP00000012897 | Uncharacterized protein. (303 aa) |
| | NFKB1 | Nuclear factor kappa B subunit 1. (969 aa) |
| | ENSMLEP00000012301 | Protein kinase domain-containing protein. (294 aa) |
| | PDPK1 | 3-phosphoinositide dependent protein kinase 1. (529 aa) |
| | CDKN1A | Cyclin dependent kinase inhibitor 1A. (164 aa) |
| | LOC105531803 | Uncharacterized protein. (734 aa) |
| | ENSMLEP00000011359 | Uncharacterized protein. (384 aa) |
| | RAF1 | Raf-1 proto-oncogene, serine/threonine kinase. (668 aa) |
| | FGFR1 | Fibroblast growth factor receptor. (853 aa) |
| | TMPRSS2 | Transmembrane serine protease 2; Belongs to the peptidase S1 family. (481 aa) |
| | PDGFRA | Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa) |
| | INSRR | Tyrosine-protein kinase receptor. (1301 aa) |
| | CDKN1B | Cyclin dependent kinase inhibitor 1B. (198 aa) |
| | CTNNB1 | Catenin beta 1. (781 aa) |
| | PDGFD | Platelet derived growth factor D. (353 aa) |
| | KRAS | KRAS proto-oncogene, GTPase. (189 aa) |
| | FGFR2 | Fibroblast growth factor receptor. (838 aa) |
| | ERAS | ES cell expressed Ras. (233 aa) |
| | LEF1 | Lymphoid enhancer binding factor 1. (399 aa) |
| | CREB3L3 | cAMP responsive element binding protein 3 like 3. (321 aa) |
| | EGF | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1152 aa) |
| | IGF1 | Insulin like growth factor 1. (159 aa) |
| | BCL2 | BCL2 apoptosis regulator. (239 aa) |
| | HSP90AB1 | Heat shock protein 90 alpha family class B member 1. (724 aa) |
| | ATF4 | Activating transcription factor 4. (351 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa) |
| | HSP90B1 | Heat shock protein 90 beta family member 1. (804 aa) |
| | SRD5A2 | 3-oxo-5-alpha-steroid 4-dehydrogenase; Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a central role in sexual differentiation and androgen physiology. (254 aa) |
| | PDGFRB | Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1106 aa) |
| | PLAT | Plasminogen activator; Belongs to the peptidase S1 family. (562 aa) |
| | SPINT1 | Serine peptidase inhibitor, Kunitz type 1. (519 aa) |
| | BAD | BCL2 associated agonist of cell death. (167 aa) |
| | CREB3 | cAMP responsive element binding protein 3. (372 aa) |
| | GSTP1 | Glutathione S-transferase pi 1; Belongs to the GST superfamily. (210 aa) |
| | PIK3R2 | Uncharacterized protein. (587 aa) |
| | NKX2-3 | NK2 homeobox 3. (282 aa) |
| | E2F1 | E2F transcription factor 1. (381 aa) |
| | CDK2 | Cyclin dependent kinase 2; Belongs to the protein kinase superfamily. (346 aa) |
| | CREBBP | CREB binding protein. (2423 aa) |
| | LOC105554720 | HATPase_c domain-containing protein. (658 aa) |
