(8 nodes) Atherosclerotic plaque network (Gorilla gorilla)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ABCA1	ATP binding cassette subfamily A member 1. (2264 aa)
	CRP	Pentaxin. (224 aa)
	ABCG1	ABC transporter domain-containing protein. (810 aa)
	SCARB1	Scavenger receptor class B member 1; Belongs to the CD36 family. (509 aa)
	VCAM1	Vascular cell adhesion molecule 1. (739 aa)
	APOE	Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...] (317 aa)
	IL6	Interleukin 6. (234 aa)
	APOB	Apolipoprotein B. (4566 aa)

Your Current Organism:

Gorilla gorilla

NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABCA1	APOB	ENSGGOP00000031163	ENSGGOP00000020316	ATP binding cassette subfamily A member 1.	Apolipoprotein B.	0.700
ABCA1	APOE	ENSGGOP00000031163	ENSGGOP00000006232	ATP binding cassette subfamily A member 1.	Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...]	0.825
ABCA1	IL6	ENSGGOP00000031163	ENSGGOP00000018546	ATP binding cassette subfamily A member 1.	Interleukin 6.	0.441
ABCA1	SCARB1	ENSGGOP00000031163	ENSGGOP00000046383	ATP binding cassette subfamily A member 1.	Scavenger receptor class B member 1; Belongs to the CD36 family.	0.681
ABCG1	APOB	ENSGGOP00000032150	ENSGGOP00000020316	ABC transporter domain-containing protein.	Apolipoprotein B.	0.497
ABCG1	APOE	ENSGGOP00000032150	ENSGGOP00000006232	ABC transporter domain-containing protein.	Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...]	0.674
ABCG1	SCARB1	ENSGGOP00000032150	ENSGGOP00000046383	ABC transporter domain-containing protein.	Scavenger receptor class B member 1; Belongs to the CD36 family.	0.657
APOB	ABCA1	ENSGGOP00000020316	ENSGGOP00000031163	Apolipoprotein B.	ATP binding cassette subfamily A member 1.	0.700
APOB	ABCG1	ENSGGOP00000020316	ENSGGOP00000032150	Apolipoprotein B.	ABC transporter domain-containing protein.	0.497
APOB	APOE	ENSGGOP00000020316	ENSGGOP00000006232	Apolipoprotein B.	Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...]	0.998
APOB	CRP	ENSGGOP00000020316	ENSGGOP00000022682	Apolipoprotein B.	Pentaxin.	0.672
APOB	IL6	ENSGGOP00000020316	ENSGGOP00000018546	Apolipoprotein B.	Interleukin 6.	0.569
APOB	SCARB1	ENSGGOP00000020316	ENSGGOP00000046383	Apolipoprotein B.	Scavenger receptor class B member 1; Belongs to the CD36 family.	0.927
APOB	VCAM1	ENSGGOP00000020316	ENSGGOP00000003220	Apolipoprotein B.	Vascular cell adhesion molecule 1.	0.455
APOE	ABCA1	ENSGGOP00000006232	ENSGGOP00000031163	Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...]	ATP binding cassette subfamily A member 1.	0.825
APOE	ABCG1	ENSGGOP00000006232	ENSGGOP00000032150	Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...]	ABC transporter domain-containing protein.	0.674
APOE	APOB	ENSGGOP00000006232	ENSGGOP00000020316	Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...]	Apolipoprotein B.	0.998
APOE	CRP	ENSGGOP00000006232	ENSGGOP00000022682	Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...]	Pentaxin.	0.672
APOE	IL6	ENSGGOP00000006232	ENSGGOP00000018546	Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...]	Interleukin 6.	0.621
APOE	SCARB1	ENSGGOP00000006232	ENSGGOP00000046383	Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...]	Scavenger receptor class B member 1; Belongs to the CD36 family.	0.798