STRINGSTRING
GAPDHS GAPDHS ACO2 ACO2 PDHX PDHX PARP8 PARP8 GCK GCK PKLR PKLR SUCLG1 SUCLG1 PFKFB1 PFKFB1 G3QI31_GORGO G3QI31_GORGO HK3 HK3 IDH3A IDH3A DLAT DLAT GOT1 GOT1 G3QJI7_GORGO G3QJI7_GORGO PPM1K PPM1K G3QKR1_GORGO G3QKR1_GORGO GCDH GCDH NIT2 NIT2 PGLS PGLS TKTL1 TKTL1 G3QPE6_GORGO G3QPE6_GORGO PGD PGD IDH2 IDH2 G3QQC9_GORGO G3QQC9_GORGO ENO2 ENO2 FBP2 FBP2 FBP1 FBP1 GOT2 GOT2 PDK3 PDK3 HK2 HK2 PFKM PFKM BPGM BPGM SUCLA2 SUCLA2 PFKFB3 PFKFB3 GAPDH GAPDH ALDOC ALDOC TKT TKT IDH3B IDH3B IL4I1 IL4I1 ENO1 ENO1 G6PC3 G6PC3 LDHD LDHD TALDO1 TALDO1 HACL1 HACL1 ME2 ME2 PFKFB4 PFKFB4 PCK1 PCK1 G3R6B6_GORGO G3R6B6_GORGO RBKS RBKS DLST DLST MDH2 MDH2 TKTL2 TKTL2 HKDC1 HKDC1 ENO4 ENO4 IDH1 IDH1 GCKR GCKR G3RB77_GORGO G3RB77_GORGO PDHB PDHB G3RCP9_GORGO G3RCP9_GORGO PDHA2 PDHA2 ALDOA ALDOA RBM45 RBM45 GOT1L1 GOT1L1 G3REG2_GORGO G3REG2_GORGO PC PC G6PC2 G6PC2 G3RGX1_GORGO G3RGX1_GORGO G3RHG0_GORGO G3RHG0_GORGO PDK2 PDK2 LDHB LDHB GLYCTK GLYCTK HK1 HK1 ACO1 ACO1 PGK1 PGK1 TIGAR TIGAR TPI1 TPI1 G3RPH6_GORGO G3RPH6_GORGO G3RR71_GORGO G3RR71_GORGO G3RRJ9_GORGO G3RRJ9_GORGO G3RS64_GORGO G3RS64_GORGO G3RT40_GORGO G3RT40_GORGO PFKL PFKL G6PC G6PC ADPGK ADPGK URB2 URB2 SUCLG2 SUCLG2 DERA DERA G3S0B2_GORGO G3S0B2_GORGO G3S168_GORGO G3S168_GORGO G3S3Q5_GORGO G3S3Q5_GORGO CS CS LDHAL6B LDHAL6B G3S8N6_GORGO G3S8N6_GORGO PDP1 PDP1 G3SF60_GORGO G3SF60_GORGO RPIA RPIA DDO DDO PGM2 PGM2 BCAT1 BCAT1 PFKP PFKP BCKDHB BCKDHB ENSGGOP00000029105 ENSGGOP00000029105 ENSGGOP00000029477 ENSGGOP00000029477 ENSGGOP00000029632 ENSGGOP00000029632 ENSGGOP00000029928 ENSGGOP00000029928 TST TST ENSGGOP00000030296 ENSGGOP00000030296 ENSGGOP00000030311 ENSGGOP00000030311 ENSGGOP00000030878 ENSGGOP00000030878 H6PD H6PD ENO3 ENO3 ENSGGOP00000031881 ENSGGOP00000031881 ENSGGOP00000032112 ENSGGOP00000032112 MPST MPST PDK1 PDK1 ENSGGOP00000033095 ENSGGOP00000033095 GPI GPI PDHA1 PDHA1 ENSGGOP00000035788 ENSGGOP00000035788 ENSGGOP00000036007 ENSGGOP00000036007 ENSGGOP00000036009 ENSGGOP00000036009 ENSGGOP00000036277 ENSGGOP00000036277 LDHC LDHC ENSGGOP00000036397 ENSGGOP00000036397 ENSGGOP00000036404 ENSGGOP00000036404 ENSGGOP00000037365 ENSGGOP00000037365 MDH1 MDH1 DHTKD1 DHTKD1 OGDH OGDH ENSGGOP00000040974 ENSGGOP00000040974 PGK2 PGK2 ENSGGOP00000042193 ENSGGOP00000042193 LDHAL6A LDHAL6A ENSGGOP00000043657 ENSGGOP00000043657 DLD DLD ENSGGOP00000044363 ENSGGOP00000044363 ENSGGOP00000045942 ENSGGOP00000045942 ENSGGOP00000045956 ENSGGOP00000045956 ENSGGOP00000046396 ENSGGOP00000046396 ALDOB ALDOB ENSGGOP00000047308 ENSGGOP00000047308 ENSGGOP00000047839 ENSGGOP00000047839 ENSGGOP00000048087 ENSGGOP00000048087 PKM PKM ENSGGOP00000049071 ENSGGOP00000049071 ENSGGOP00000049142 ENSGGOP00000049142 ME3 ME3 ENSGGOP00000049959 ENSGGOP00000049959 ENSGGOP00000049961 ENSGGOP00000049961 OGDHL OGDHL RPE RPE ENSGGOP00000051025 ENSGGOP00000051025 ENSGGOP00000051824 ENSGGOP00000051824 ENSGGOP00000051851 ENSGGOP00000051851 IDH3G IDH3G ENSGGOP00000052223 ENSGGOP00000052223 PFKFB2 PFKFB2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GAPDHSGlyceraldehyde-3-phosphate dehydrogenase. (408 aa)
ACO2Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (780 aa)
PDHXDihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (501 aa)
PARP8Poly [ADP-ribose] polymerase. (837 aa)
GCKPhosphotransferase. (466 aa)
PKLRPyruvate kinase; Belongs to the pyruvate kinase family. (574 aa)
SUCLG1Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. (346 aa)
PFKFB16-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1. (471 aa)
G3QI31_GORGOMalate dehydrogenase 1B. (500 aa)
HK3Hexokinase 3. (923 aa)
IDH3AIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (366 aa)
DLATAcetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (645 aa)
GOT1Aspartate aminotransferase. (413 aa)
G3QJI7_GORGOTriosephosphate isomerase. (210 aa)
PPM1KProtein phosphatase, Mg2+/Mn2+ dependent 1K. (372 aa)
G3QKR1_GORGOUncharacterized protein. (244 aa)
GCDHGlutaryl-CoA dehydrogenase. (437 aa)
NIT2Nitrilase family member 2. (306 aa)
PGLSGlucosamine_iso domain-containing protein. (167 aa)
TKTL1Transketolase like 1. (596 aa)
G3QPE6_GORGOPhosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (253 aa)
PGD6-phosphogluconate dehydrogenase, decarboxylating; Belongs to the 6-phosphogluconate dehydrogenase family. (434 aa)
IDH2Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (452 aa)
G3QQC9_GORGOGlucose-6-phosphate dehydrogenase. (561 aa)
ENO2Enolase 2. (434 aa)
FBP2Fructose-bisphosphatase 2; Belongs to the FBPase class 1 family. (339 aa)
FBP1Fructose-bisphosphatase 1; Belongs to the FBPase class 1 family. (338 aa)
GOT2Aspartate aminotransferase. (430 aa)
PDK3Protein-serine/threonine kinase. (423 aa)
HK2Hexokinase 2. (917 aa)
PFKMATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (851 aa)
BPGMPhosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (259 aa)
SUCLA2Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (463 aa)
PFKFB36PF2K domain-containing protein. (644 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase. (335 aa)
ALDOCFructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (364 aa)
TKTTRANSKETOLASE_1 domain-containing protein. (631 aa)
IDH3BIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (385 aa)
IL4I1Amine oxidase. (589 aa)
ENO1Enolase 1. (434 aa)
G6PC3Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (346 aa)
LDHDLactate dehydrogenase D. (484 aa)
TALDO1Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (337 aa)
HACL12-hydroxyacyl-CoA lyase 1; Belongs to the TPP enzyme family. (578 aa)
ME2Malic enzyme. (584 aa)
PFKFB46-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4. (469 aa)
PCK1Phosphoenolpyruvate carboxykinase 1. (622 aa)
G3R6B6_GORGOUncharacterized protein. (202 aa)
RBKSRibokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (322 aa)
DLSTDihydrolipoamide S-succinyltransferase. (453 aa)
MDH2Malate dehydrogenase. (338 aa)
TKTL2Transketolase like 2. (625 aa)
HKDC1Hexokinase domain containing 1. (917 aa)
ENO4Enolase 4. (628 aa)
IDH1Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (414 aa)
GCKRGlucokinase regulator. (625 aa)
G3RB77_GORGO2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). (448 aa)
PDHBPyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (359 aa)
G3RCP9_GORGODihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (507 aa)
PDHA2Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (388 aa)
ALDOAFructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (418 aa)
RBM45RNA binding motif protein 45. (474 aa)
GOT1L1Glutamic-oxaloacetic transaminase 1 like 1. (421 aa)
G3REG2_GORGOGlutamic--pyruvic transaminase. (496 aa)
PCPyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1178 aa)
G6PC2Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (355 aa)
G3RGX1_GORGOL-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (361 aa)
G3RHG0_GORGOPoly [ADP-ribose] polymerase. (559 aa)
PDK2Protein-serine/threonine kinase. (407 aa)
LDHBL-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (291 aa)
GLYCTKGlycerate kinase. (523 aa)
HK1Hexokinase 1. (921 aa)
ACO1Aconitase 1; Belongs to the aconitase/IPM isomerase family. (889 aa)
PGK1Phosphoglycerate kinase. (394 aa)
TIGARTP53 induced glycolysis regulatory phosphatase. (270 aa)
TPI1Triosephosphate isomerase; Triosephosphate isomerase is an extremely efficient metabolic enzyme that catalyzes the interconversion between dihydroxyacetone phosphate (DHAP) and D-glyceraldehyde-3-phosphate (G3P) in glycolysis and gluconeogenesis. (249 aa)
G3RPH6_GORGOL-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (359 aa)
G3RR71_GORGOMalic enzyme. (545 aa)
G3RRJ9_GORGOPyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (428 aa)
G3RS64_GORGOGp_dh_N domain-containing protein; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (122 aa)
G3RT40_GORGOPyruvate kinase; Belongs to the pyruvate kinase family. (469 aa)
PFKLATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (780 aa)
G6PCGlucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (357 aa)
ADPGKADP dependent glucokinase. (442 aa)
URB2URB2 ribosome biogenesis homolog. (1524 aa)
SUCLG2Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (440 aa)
DERADeoxyribose-phosphate aldolase. (322 aa)
G3S0B2_GORGOL-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (358 aa)
G3S168_GORGOGp_dh_N domain-containing protein. (330 aa)
G3S3Q5_GORGOUncharacterized protein. (706 aa)
CSCitrate synthase; Belongs to the citrate synthase family. (466 aa)
LDHAL6BL-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (381 aa)
G3S8N6_GORGOGp_dh_C domain-containing protein. (175 aa)
PDP1Pyruvate dehyrogenase phosphatase catalytic subunit 1. (596 aa)
G3SF60_GORGOUncharacterized protein. (160 aa)
RPIARibose 5-phosphate isomerase A. (311 aa)
DDOD-aspartate oxidase. (369 aa)
PGM2Phosphoglucomutase 2. (612 aa)
BCAT1Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (420 aa)
PFKPPFK domain-containing protein. (275 aa)
BCKDHBBranched chain keto acid dehydrogenase E1 subunit beta. (343 aa)
ENSGGOP00000029105Uncharacterized protein. (416 aa)
ENSGGOP00000029477PFK domain-containing protein. (202 aa)
ENSGGOP00000029632L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (340 aa)
ENSGGOP00000029928Uncharacterized protein. (145 aa)
TSTRhodanese domain-containing protein. (243 aa)
ENSGGOP00000030296Gp_dh_N domain-containing protein. (360 aa)
ENSGGOP00000030311Transket_pyr domain-containing protein. (575 aa)
ENSGGOP00000030878Gp_dh_N domain-containing protein. (239 aa)
H6PDHexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase. (802 aa)
ENO3Enolase 3. (434 aa)
ENSGGOP00000031881Phosphoglycerate kinase. (384 aa)
ENSGGOP00000032112MYCBP associated protein. (976 aa)
MPSTSulfurtransferase. (317 aa)
PDK1Protein-serine/threonine kinase. (456 aa)
ENSGGOP00000033095Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (403 aa)
GPIGlucose-6-phosphate isomerase; Belongs to the GPI family. (573 aa)
PDHA1Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial isoform X1. (109 aa)
ENSGGOP00000035788Gp_dh_N domain-containing protein; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (260 aa)
ENSGGOP00000036007Uncharacterized protein. (314 aa)
ENSGGOP00000036009Uncharacterized protein. (311 aa)
ENSGGOP000000362776PGD domain-containing protein. (432 aa)
LDHCL-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (332 aa)
ENSGGOP00000036397Uncharacterized protein. (250 aa)
ENSGGOP00000036404Uncharacterized protein. (648 aa)
ENSGGOP00000037365Uncharacterized protein. (137 aa)
MDH1Malate dehydrogenase. (352 aa)
DHTKD1Dehydrogenase E1 and transketolase domain containing 1. (919 aa)
OGDHOxoglutarate dehydrogenase. (1018 aa)
ENSGGOP00000040974Uncharacterized protein. (318 aa)
PGK2Phosphoglycerate kinase. (417 aa)
ENSGGOP00000042193Pyruvate kinase; Belongs to the pyruvate kinase family. (310 aa)
LDHAL6AL-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (332 aa)
ENSGGOP00000043657Pyruvate kinase; Belongs to the pyruvate kinase family. (299 aa)
DLDDihydrolipoyl dehydrogenase. (515 aa)
ENSGGOP00000044363Iso_dh domain-containing protein. (65 aa)
ENSGGOP00000045942Gp_dh_N domain-containing protein. (310 aa)
ENSGGOP00000045956Triosephosphate isomerase. (273 aa)
ENSGGOP00000046396Uncharacterized protein. (74 aa)
ALDOBFructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (364 aa)
ENSGGOP00000047308Uncharacterized protein. (231 aa)
ENSGGOP00000047839L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (351 aa)
ENSGGOP00000048087Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (445 aa)
PKMPyruvate kinase; Belongs to the pyruvate kinase family. (556 aa)
ENSGGOP00000049071Phosphoglycerate kinase. (215 aa)
ENSGGOP00000049142ATP-grasp_2 domain-containing protein. (350 aa)
ME3Malic enzyme. (604 aa)
ENSGGOP00000049959Transket_pyr domain-containing protein. (400 aa)
ENSGGOP00000049961Uncharacterized protein; Belongs to the LDH/MDH superfamily. (308 aa)
OGDHLOxoglutarate dehydrogenase like. (1019 aa)
RPEUncharacterized protein. (82 aa)
ENSGGOP00000051025Aminotran_1_2 domain-containing protein. (389 aa)
ENSGGOP00000051824Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (415 aa)
ENSGGOP00000051851Uncharacterized protein; Belongs to the LDH/MDH superfamily. (336 aa)
IDH3GIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (393 aa)
ENSGGOP00000052223Triosephosphate isomerase. (137 aa)
PFKFB26-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2. (522 aa)
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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