(22 nodes) Mixed, incl. Lactate/malate dehydrogenase, N-terminal, and Phenylalanine, tyrosine and tryptophan biosynthesis network (Gorilla gorilla)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	GOT1	Aspartate aminotransferase. (413 aa)
	NIT2	Nitrilase family member 2. (306 aa)
	GOT2	Aspartate aminotransferase. (430 aa)
	IL4I1	Amine oxidase. (589 aa)
	LDHD	Lactate dehydrogenase D. (484 aa)
	ME2	Malic enzyme. (584 aa)
	MDH2	Malate dehydrogenase. (338 aa)
	GOT1L1	Glutamic-oxaloacetic transaminase 1 like 1. (421 aa)
	PC	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1178 aa)
	G3RGX1_GORGO	L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (361 aa)
	LDHB	L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (291 aa)
	G3S0B2_GORGO	L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (358 aa)
	LDHAL6B	L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (381 aa)
	DDO	D-aspartate oxidase. (369 aa)
	BCAT1	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (420 aa)
	TST	Rhodanese domain-containing protein. (243 aa)
	MPST	Sulfurtransferase. (317 aa)
	LDHC	L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (332 aa)
	MDH1	Malate dehydrogenase. (352 aa)
	LDHAL6A	L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (332 aa)
	ENSGGOP00000047839	L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (351 aa)
	ME3	Malic enzyme. (604 aa)

Your Current Organism:

Gorilla gorilla

NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BCAT1	ENSGGOP00000047839	ENSGGOP00000027946	ENSGGOP00000047839	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.	L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily.	0.827
BCAT1	G3RGX1_GORGO	ENSGGOP00000027946	ENSGGOP00000014883	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.	L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily.	0.836
BCAT1	G3S0B2_GORGO	ENSGGOP00000027946	ENSGGOP00000021506	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.	L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily.	0.829
BCAT1	IL4I1	ENSGGOP00000027946	ENSGGOP00000009980	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.	Amine oxidase.	0.911
BCAT1	LDHAL6A	ENSGGOP00000027946	ENSGGOP00000043001	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.	L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily.	0.827
BCAT1	LDHAL6B	ENSGGOP00000027946	ENSGGOP00000023993	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.	L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily.	0.827
BCAT1	LDHB	ENSGGOP00000027946	ENSGGOP00000015376	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.	L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily.	0.826
BCAT1	LDHC	ENSGGOP00000027946	ENSGGOP00000036371	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.	L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily.	0.826
BCAT1	NIT2	ENSGGOP00000027946	ENSGGOP00000003662	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.	Nitrilase family member 2.	0.480
DDO	GOT1	ENSGGOP00000027320	ENSGGOP00000002510	D-aspartate oxidase.	Aspartate aminotransferase.	0.927
DDO	GOT1L1	ENSGGOP00000027320	ENSGGOP00000013875	D-aspartate oxidase.	Glutamic-oxaloacetic transaminase 1 like 1.	0.942
DDO	GOT2	ENSGGOP00000027320	ENSGGOP00000005648	D-aspartate oxidase.	Aspartate aminotransferase.	0.917
DDO	IL4I1	ENSGGOP00000027320	ENSGGOP00000009980	D-aspartate oxidase.	Amine oxidase.	0.912
DDO	MDH1	ENSGGOP00000027320	ENSGGOP00000039797	D-aspartate oxidase.	Malate dehydrogenase.	0.825
DDO	MDH2	ENSGGOP00000027320	ENSGGOP00000011503	D-aspartate oxidase.	Malate dehydrogenase.	0.805
DDO	NIT2	ENSGGOP00000027320	ENSGGOP00000003662	D-aspartate oxidase.	Nitrilase family member 2.	0.918
DDO	PC	ENSGGOP00000027320	ENSGGOP00000014135	D-aspartate oxidase.	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	0.836
ENSGGOP00000047839	BCAT1	ENSGGOP00000047839	ENSGGOP00000027946	L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily.	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.	0.827
ENSGGOP00000047839	GOT1	ENSGGOP00000047839	ENSGGOP00000002510	L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily.	Aspartate aminotransferase.	0.797
ENSGGOP00000047839	GOT1L1	ENSGGOP00000047839	ENSGGOP00000013875	L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily.	Glutamic-oxaloacetic transaminase 1 like 1.	0.787