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| | GAB1 | GRB2 associated binding protein 1. (724 aa) |
| | HBEGF | Heparin binding EGF like growth factor. (208 aa) |
| | INPP5D | Inositol polyphosphate-5-phosphatase D. (1066 aa) |
| | FGR | Tyrosine-protein kinase. (529 aa) |
| | FLT3 | Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (993 aa) |
| | FGF21 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (209 aa) |
| | GRAP2 | GRB2 related adaptor protein 2. (330 aa) |
| | G3QHV0_GORGO | Linker for activation of T cells. (268 aa) |
| | PDGFD | Platelet derived growth factor D. (370 aa) |
| | FGF16 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa) |
| | SORBS3 | Sorbin and SH3 domain containing 3. (671 aa) |
| | FRS3 | Fibroblast growth factor receptor substrate 3. (492 aa) |
| | PIK3R5 | Phosphoinositide-3-kinase regulatory subunit 5. (881 aa) |
| | VEGFD | Vascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. (354 aa) |
| | FGF5 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (268 aa) |
| | FGF23 | Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (251 aa) |
| | ITK | Tyrosine-protein kinase. (620 aa) |
| | EREG | EGF-like domain-containing protein. (222 aa) |
| | G3QMP2_GORGO | Protein tyrosine phosphatase non-receptor type 22. (693 aa) |
| | ERBB2 | Receptor protein-tyrosine kinase. (1255 aa) |
| | FGF10 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa) |
| | IGF1 | IlGF domain-containing protein. (196 aa) |
| | FGF9 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) |
| | G3QRG5_GORGO | Neurotrophin 4; Belongs to the NGF-beta family. (210 aa) |
| | FGF7 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa) |
| | EGF | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1183 aa) |
| | GRB2 | Growth factor receptor bound protein 2. (217 aa) |
| | LCTL | Lactase like; Belongs to the glycosyl hydrolase 1 family. (567 aa) |
| | GRB10 | Growth factor receptor bound protein 10. (594 aa) |
| | SORT1 | Sortilin. (831 aa) |
| | LCP2 | Lymphocyte cytosolic protein 2. (533 aa) |
| | CRK | CRK proto-oncogene, adaptor protein. (304 aa) |
| | FLT4 | Fms related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1319 aa) |
| | PTPN1 | Tyrosine-protein phosphatase non-receptor type. (435 aa) |
| | FGF17 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa) |
| | FGF18 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa) |
| | PDGFRB | Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1106 aa) |
| | KL | Uncharacterized protein; Belongs to the glycosyl hydrolase 1 family. (739 aa) |
| | TLN1 | FERM domain-containing protein. (261 aa) |
| | FGF6 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) |
| | PLCG1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1290 aa) |
| | G3QZ51_GORGO | Fibroblast growth factor receptor. (822 aa) |
| | NGFR | Nerve growth factor receptor. (427 aa) |
| | G3QZR8_GORGO | Uncharacterized protein. (533 aa) |
| | PDGFC | Platelet derived growth factor C; Belongs to the PDGF/VEGF growth factor family. (345 aa) |
| | TIE1 | Tyrosine kinase with immunoglobulin like and EGF like domains 1. (1138 aa) |
| | FLT1 | Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1302 aa) |
| | TXK | Tyrosine-protein kinase. (527 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | PIK3CB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1041 aa) |
| | FGF20 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (214 aa) |
| | FER | Tyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa) |
| | ANGPT2 | Angiopoietin 2. (496 aa) |
| | FGF4 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa) |
| | GAB2 | GRB2 associated binding protein 2. (675 aa) |
| | FLT3LG | Fms related tyrosine kinase 3 ligand. (235 aa) |
| | PAG1 | Phosphoprotein membrane anchor with glycosphingolipid microdomains 1. (432 aa) |
| | SYK | Tyrosine-protein kinase. (635 aa) |
| | SHC4 | SHC adaptor protein 4. (630 aa) |
| | APBB1IP | Amyloid beta precursor protein binding family B member 1 interacting protein. (664 aa) |
| | ABL1 | Tyrosine-protein kinase. (1149 aa) |
| | PDGFRA | Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa) |
| | G3R689_GORGO | Vinculin. (1134 aa) |
| | SPRY2 | Sprouty RTK signaling antagonist 2. (315 aa) |
| | CSK | Tyrosine-protein kinase. (450 aa) |
| | NRG3 | Neuregulin 3. (720 aa) |
| | VEGFB | PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (168 aa) |
| | VAV1 | Vav guanine nucleotide exchange factor 1. (788 aa) |
| | G3R9C2_GORGO | Proline-serine-threonine phosphatase interacting protein 1. (418 aa) |
| | G3R9L0_GORGO | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta; Belongs to the PI3/PI4-kinase family. (1072 aa) |
| | SHC3 | SHC adaptor protein 3. (598 aa) |
| | G3RAC9_GORGO | Vascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (395 aa) |
| | GRAP | GRB2 related adaptor protein. (217 aa) |
| | KDR | Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa) |
| | IGF1R | Tyrosine-protein kinase receptor. (1367 aa) |
| | GAB4 | GRB2 associated binding protein family member 4. (575 aa) |
| | G3RBA4_GORGO | Interleukin 34. (216 aa) |
| | FGFR1 | Fibroblast growth factor receptor. (820 aa) |
| | SHC1 | SHC adaptor protein 1. (584 aa) |
| | KLB | Klotho beta. (1044 aa) |
| | INSRR | Tyrosine-protein kinase receptor. (1297 aa) |
| | BTC | Betacellulin. (178 aa) |
| | NTRK2 | Tyrosine-protein kinase receptor. (767 aa) |
| | PDGFRL | Platelet derived growth factor receptor like. (375 aa) |
| | G3RFH4_GORGO | Tyrosine-protein kinase. (508 aa) |
| | PGF | PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (221 aa) |
| | FGF8 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa) |
| | KIT | Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (976 aa) |
| | IRS2 | Insulin receptor substrate 2. (1220 aa) |
| | PDGFB | Platelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (220 aa) |
| | PTK2B | Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa) |
| | SORCS2 | Sortilin related VPS10 domain containing receptor 2. (1097 aa) |
| | G3RIK8_GORGO | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (167 aa) |
| | TEK | TEK receptor tyrosine kinase. (1124 aa) |
| | FGFBP1 | Fibroblast growth factor binding protein 1. (234 aa) |
| | CSF1 | Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...] (554 aa) |
| | PTPN18 | Protein tyrosine phosphatase non-receptor type 18. (458 aa) |
| | ANGPT4 | Angiopoietin 4. (503 aa) |
| | G3RLC3_GORGO | SH2 domain-containing protein. (568 aa) |
| | CSF1R | Colony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (972 aa) |
| | CBL | Cbl proto-oncogene. (906 aa) |
| | FGFR4 | Fibroblast growth factor receptor. (802 aa) |
| | FGF1 | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa) |
| | ITGA1 | Integrin subunit alpha 1; Belongs to the integrin alpha chain family. (1179 aa) |
| | INSR | Tyrosine-protein kinase receptor. (1347 aa) |
| | SRC | Tyrosine-protein kinase. (542 aa) |
| | TEC | Tyrosine-protein kinase. (631 aa) |
| | G3RS61_GORGO | Cbl proto-oncogene B. (860 aa) |
| | G3RSU6_GORGO | Uncharacterized protein. (499 aa) |
| | PIK3R3 | Uncharacterized protein. (507 aa) |
| | G3RV02_GORGO | SH3 domain containing kinase binding protein 1. (671 aa) |
| | FGF3 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (239 aa) |
| | FGF11 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (227 aa) |
| | G3RZ13_GORGO | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa) |
| | SPRY3 | Sprouty RTK signaling antagonist 3. (288 aa) |
| | AREG | EGF-like domain-containing protein. (274 aa) |
| | PTK2 | Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1096 aa) |
| | ANGPT1 | Angiopoietin 1. (498 aa) |
| | G3S355_GORGO | SH2 domain-containing protein. (85 aa) |
| | SOS1 | SOS Ras/Rac guanine nucleotide exchange factor 1. (1333 aa) |
| | KITLG | Kit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (273 aa) |
| | G3S653_GORGO | Uncharacterized protein. (443 aa) |
| | PIK3CG | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1102 aa) |
| | FCGR2B | Uncharacterized protein. (310 aa) |
| | YES1 | Tyrosine-protein kinase. (558 aa) |
| | BTK | Tyrosine-protein kinase. (693 aa) |
| | NCK1 | Cytoplasmic protein. (377 aa) |
| | BLNK | B cell linker. (456 aa) |
| | G3SE26_GORGO | Talin 2. (2467 aa) |
| | VAV2 | Vav guanine nucleotide exchange factor 2. (878 aa) |
| | PTPN12 | Tyrosine-protein phosphatase non-receptor type 12; Dephosphorylates a range of proteins, and thereby regulates cellular signaling cascades. (780 aa) |
| | PLCG2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa) |
| | HCK | Tyrosine-protein kinase. (526 aa) |
| | FGFRL1 | Fibroblast growth factor receptor like 1. (539 aa) |
| | PTPN11 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa) |
| | G3SKI0_GORGO | Uncharacterized protein. (1294 aa) |
| | FRS2 | Fibroblast growth factor receptor substrate 2. (522 aa) |
| | NCK2 | Cytoplasmic protein. (380 aa) |
| | ENSGGOP00000030268 | Uncharacterized protein. (596 aa) |
| | IRS1 | Insulin receptor substrate 1. (1241 aa) |
| | EPGN | Epithelial mitogen. (154 aa) |
| | ENSGGOP00000031915 | Uncharacterized protein. (110 aa) |
| | BDNF | Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. (329 aa) |
| | TGFB1I1 | Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways. (461 aa) |
| | FGF2 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (258 aa) |
| | NGF | Beta-nerve growth factor; Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades to regulate neuronal proliferation, differentiation and survival (By similarity). The immature NGF precursor (proNGF) functions as ligand for the heterodimeric receptor formed by SORCS2 and NGFR, and activates cellular signaling cascades that lead to inactivation of RAC1 and/or RAC2, reorganization of the actin cytoskeleton and neuronal growth cone colla [...] (123 aa) |
| | ENSGGOP00000034632 | Recep_L_domain domain-containing protein. (183 aa) |
| | INS | Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (200 aa) |
| | ENSGGOP00000036103 | Uncharacterized protein. (509 aa) |
| | ENSGGOP00000037095 | Uncharacterized protein. (575 aa) |
| | ERBB3 | Protein kinase domain-containing protein. (593 aa) |
| | HGF | Hepatocyte growth factor; Belongs to the peptidase S1 family. (733 aa) |
| | PDGFA | PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (234 aa) |
| | CRKL | Uncharacterized protein. (201 aa) |
| | NTRK1 | Tyrosine-protein kinase receptor. (796 aa) |
| | INPPL1 | Inositol polyphosphate phosphatase like 1. (1253 aa) |
| | EGFR | Receptor protein-tyrosine kinase. (1205 aa) |
| | ENSGGOP00000041668 | Fibroblast growth factor receptor. (808 aa) |
| | MET | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] (1409 aa) |
| | NRG1 | Neuregulin 1. (713 aa) |
| | ERBB4 | Receptor protein-tyrosine kinase. (1308 aa) |
| | NRG4 | Neuregulin 4. (117 aa) |
| | NTF3 | Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (275 aa) |
| | ENSGGOP00000044113 | Uncharacterized protein. (1081 aa) |
| | TGFA | Transforming growth factor alpha. (166 aa) |
| | ENSGGOP00000048050 | SH2 domain-containing protein. (132 aa) |
| | VAV3 | Vav guanine nucleotide exchange factor 3. (875 aa) |
| | ENSGGOP00000048385 | Rap guanine nucleotide exchange factor 1. (1095 aa) |
| | SOS2 | SOS Ras/Rho guanine nucleotide exchange factor 2. (1331 aa) |
| | PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (723 aa) |
| | LPXN | Leupaxin; Transcriptional coactivator for androgen receptor (AR) and serum response factor (SRF). Contributes to the regulation of cell adhesion, spreading and cell migration and acts as a negative regulator in integrin-mediated cell adhesion events. Suppresses the integrin- induced tyrosine phosphorylation of paxillin (PXN). (391 aa) |
| | VEGFC | PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (230 aa) |
| | BCAR1 | BCAR1 scaffold protein, Cas family member. (916 aa) |
