STRINGSTRING
GAB1 GAB1 INPP5D INPP5D FGR FGR GRAP2 GRAP2 G3QHV0_GORGO G3QHV0_GORGO SORBS3 SORBS3 FRS3 FRS3 PIK3R5 PIK3R5 ITK ITK G3QMP2_GORGO G3QMP2_GORGO GRB2 GRB2 LCP2 LCP2 CRK CRK TLN1 TLN1 PLCG1 PLCG1 TXK TXK PIK3CA PIK3CA PIK3CB PIK3CB FER FER GAB2 GAB2 PAG1 PAG1 SYK SYK SHC4 SHC4 APBB1IP APBB1IP ABL1 ABL1 G3R689_GORGO G3R689_GORGO CSK CSK VAV1 VAV1 G3R9C2_GORGO G3R9C2_GORGO G3R9L0_GORGO G3R9L0_GORGO SHC3 SHC3 GRAP GRAP GAB4 GAB4 SHC1 SHC1 G3RFH4_GORGO G3RFH4_GORGO PTK2B PTK2B PTPN18 PTPN18 CBL CBL ITGA1 ITGA1 SRC SRC TEC TEC G3RSU6_GORGO G3RSU6_GORGO PIK3R3 PIK3R3 PTK2 PTK2 G3S355_GORGO G3S355_GORGO SOS1 SOS1 PIK3CG PIK3CG FCGR2B FCGR2B YES1 YES1 BTK BTK NCK1 NCK1 BLNK BLNK G3SE26_GORGO G3SE26_GORGO VAV2 VAV2 PTPN12 PTPN12 PLCG2 PLCG2 HCK HCK PTPN11 PTPN11 G3SKI0_GORGO G3SKI0_GORGO FRS2 FRS2 NCK2 NCK2 ENSGGOP00000030268 ENSGGOP00000030268 ENSGGOP00000031915 ENSGGOP00000031915 TGFB1I1 TGFB1I1 ENSGGOP00000036103 ENSGGOP00000036103 ENSGGOP00000037095 ENSGGOP00000037095 CRKL CRKL INPPL1 INPPL1 ENSGGOP00000044113 ENSGGOP00000044113 ENSGGOP00000048050 ENSGGOP00000048050 VAV3 VAV3 ENSGGOP00000048385 ENSGGOP00000048385 SOS2 SOS2 PIK3R1 PIK3R1 LPXN LPXN BCAR1 BCAR1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GAB1GRB2 associated binding protein 1. (724 aa)
INPP5DInositol polyphosphate-5-phosphatase D. (1066 aa)
FGRTyrosine-protein kinase. (529 aa)
GRAP2GRB2 related adaptor protein 2. (330 aa)
G3QHV0_GORGOLinker for activation of T cells. (268 aa)
SORBS3Sorbin and SH3 domain containing 3. (671 aa)
FRS3Fibroblast growth factor receptor substrate 3. (492 aa)
PIK3R5Phosphoinositide-3-kinase regulatory subunit 5. (881 aa)
ITKTyrosine-protein kinase. (620 aa)
G3QMP2_GORGOProtein tyrosine phosphatase non-receptor type 22. (693 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
LCP2Lymphocyte cytosolic protein 2. (533 aa)
CRKCRK proto-oncogene, adaptor protein. (304 aa)
TLN1FERM domain-containing protein. (261 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1290 aa)
TXKTyrosine-protein kinase. (527 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1041 aa)
FERTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa)
GAB2GRB2 associated binding protein 2. (675 aa)
PAG1Phosphoprotein membrane anchor with glycosphingolipid microdomains 1. (432 aa)
SYKTyrosine-protein kinase. (635 aa)
SHC4SHC adaptor protein 4. (630 aa)
APBB1IPAmyloid beta precursor protein binding family B member 1 interacting protein. (664 aa)
ABL1Tyrosine-protein kinase. (1149 aa)
G3R689_GORGOVinculin. (1134 aa)
CSKTyrosine-protein kinase. (450 aa)
VAV1Vav guanine nucleotide exchange factor 1. (788 aa)
G3R9C2_GORGOProline-serine-threonine phosphatase interacting protein 1. (418 aa)
G3R9L0_GORGOPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta; Belongs to the PI3/PI4-kinase family. (1072 aa)
SHC3SHC adaptor protein 3. (598 aa)
GRAPGRB2 related adaptor protein. (217 aa)
GAB4GRB2 associated binding protein family member 4. (575 aa)
SHC1SHC adaptor protein 1. (584 aa)
G3RFH4_GORGOTyrosine-protein kinase. (508 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
PTPN18Protein tyrosine phosphatase non-receptor type 18. (458 aa)
CBLCbl proto-oncogene. (906 aa)
ITGA1Integrin subunit alpha 1; Belongs to the integrin alpha chain family. (1179 aa)
SRCTyrosine-protein kinase. (542 aa)
TECTyrosine-protein kinase. (631 aa)
G3RSU6_GORGOUncharacterized protein. (499 aa)
PIK3R3Uncharacterized protein. (507 aa)
PTK2Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1096 aa)
G3S355_GORGOSH2 domain-containing protein. (85 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1333 aa)
PIK3CGPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1102 aa)
FCGR2BUncharacterized protein. (310 aa)
YES1Tyrosine-protein kinase. (558 aa)
BTKTyrosine-protein kinase. (693 aa)
NCK1Cytoplasmic protein. (377 aa)
BLNKB cell linker. (456 aa)
G3SE26_GORGOTalin 2. (2467 aa)
VAV2Vav guanine nucleotide exchange factor 2. (878 aa)
PTPN12Tyrosine-protein phosphatase non-receptor type 12; Dephosphorylates a range of proteins, and thereby regulates cellular signaling cascades. (780 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
HCKTyrosine-protein kinase. (526 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
G3SKI0_GORGOUncharacterized protein. (1294 aa)
FRS2Fibroblast growth factor receptor substrate 2. (522 aa)
NCK2Cytoplasmic protein. (380 aa)
ENSGGOP00000030268Uncharacterized protein. (596 aa)
ENSGGOP00000031915Uncharacterized protein. (110 aa)
TGFB1I1Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways. (461 aa)
ENSGGOP00000036103Uncharacterized protein. (509 aa)
ENSGGOP00000037095Uncharacterized protein. (575 aa)
CRKLUncharacterized protein. (201 aa)
INPPL1Inositol polyphosphate phosphatase like 1. (1253 aa)
ENSGGOP00000044113Uncharacterized protein. (1081 aa)
ENSGGOP00000048050SH2 domain-containing protein. (132 aa)
VAV3Vav guanine nucleotide exchange factor 3. (875 aa)
ENSGGOP00000048385Rap guanine nucleotide exchange factor 1. (1095 aa)
SOS2SOS Ras/Rho guanine nucleotide exchange factor 2. (1331 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (723 aa)
LPXNLeupaxin; Transcriptional coactivator for androgen receptor (AR) and serum response factor (SRF). Contributes to the regulation of cell adhesion, spreading and cell migration and acts as a negative regulator in integrin-mediated cell adhesion events. Suppresses the integrin- induced tyrosine phosphorylation of paxillin (PXN). (391 aa)
BCAR1BCAR1 scaffold protein, Cas family member. (916 aa)
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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