(12 nodes) Phosphatidylinositol 3-kinase complex, class IA, and Fc-gamma receptor I complex binding network (Gorilla gorilla)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	FGR	Tyrosine-protein kinase. (529 aa)
	PIK3R5	Phosphoinositide-3-kinase regulatory subunit 5. (881 aa)
	ITK	Tyrosine-protein kinase. (620 aa)
	PIK3CA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	PIK3CB	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1041 aa)
	G3R9L0_GORGO	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta; Belongs to the PI3/PI4-kinase family. (1072 aa)
	SHC3	SHC adaptor protein 3. (598 aa)
	PIK3R3	Uncharacterized protein. (507 aa)
	PIK3CG	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1102 aa)
	HCK	Tyrosine-protein kinase. (526 aa)
	ENSGGOP00000030268	Uncharacterized protein. (596 aa)
	PIK3R1	Phosphoinositide-3-kinase regulatory subunit 1. (723 aa)

Your Current Organism:

Gorilla gorilla

NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSGGOP00000030268	G3R9L0_GORGO	ENSGGOP00000030268	ENSGGOP00000012094	Uncharacterized protein.	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta; Belongs to the PI3/PI4-kinase family.	0.996
ENSGGOP00000030268	HCK	ENSGGOP00000030268	ENSGGOP00000028067	Uncharacterized protein.	Tyrosine-protein kinase.	0.470
ENSGGOP00000030268	PIK3CA	ENSGGOP00000030268	ENSGGOP00000009158	Uncharacterized protein.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.998
ENSGGOP00000030268	PIK3CB	ENSGGOP00000030268	ENSGGOP00000009368	Uncharacterized protein.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.999
ENSGGOP00000030268	PIK3CG	ENSGGOP00000030268	ENSGGOP00000023989	Uncharacterized protein.	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family.	0.973
ENSGGOP00000030268	PIK3R1	ENSGGOP00000030268	ENSGGOP00000050489	Uncharacterized protein.	Phosphoinositide-3-kinase regulatory subunit 1.	0.984
ENSGGOP00000030268	PIK3R3	ENSGGOP00000030268	ENSGGOP00000019086	Uncharacterized protein.	Uncharacterized protein.	0.985
ENSGGOP00000030268	PIK3R5	ENSGGOP00000030268	ENSGGOP00000002742	Uncharacterized protein.	Phosphoinositide-3-kinase regulatory subunit 5.	0.872
ENSGGOP00000030268	SHC3	ENSGGOP00000030268	ENSGGOP00000012215	Uncharacterized protein.	SHC adaptor protein 3.	0.520
FGR	G3R9L0_GORGO	ENSGGOP00000000763	ENSGGOP00000012094	Tyrosine-protein kinase.	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta; Belongs to the PI3/PI4-kinase family.	0.434
FGR	HCK	ENSGGOP00000000763	ENSGGOP00000028067	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.699
FGR	ITK	ENSGGOP00000000763	ENSGGOP00000003555	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.925
FGR	PIK3CA	ENSGGOP00000000763	ENSGGOP00000009158	Tyrosine-protein kinase.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.937
FGR	PIK3CB	ENSGGOP00000000763	ENSGGOP00000009368	Tyrosine-protein kinase.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.937
FGR	PIK3CG	ENSGGOP00000000763	ENSGGOP00000023989	Tyrosine-protein kinase.	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family.	0.936
FGR	PIK3R1	ENSGGOP00000000763	ENSGGOP00000050489	Tyrosine-protein kinase.	Phosphoinositide-3-kinase regulatory subunit 1.	0.938
FGR	PIK3R3	ENSGGOP00000000763	ENSGGOP00000019086	Tyrosine-protein kinase.	Uncharacterized protein.	0.934
FGR	PIK3R5	ENSGGOP00000000763	ENSGGOP00000002742	Tyrosine-protein kinase.	Phosphoinositide-3-kinase regulatory subunit 5.	0.940
FGR	SHC3	ENSGGOP00000000763	ENSGGOP00000012215	Tyrosine-protein kinase.	SHC adaptor protein 3.	0.939
G3R9L0_GORGO	ENSGGOP00000030268	ENSGGOP00000012094	ENSGGOP00000030268	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.996